In a breast cancer series (n = 54), preoperative fine needle aspiration (FNA) was compared with biopsy at primary surgery as a source of material for the determination of progesterone receptor (PgR) ...content by enzyme immuno assay. The respective results manifested a strong correlation (r(s) = 0.82). The fact that PgR content was usually higher in FNA samples than in the corresponding biopsy samples and the finding that 11% of the tumours were PgR positive in FNA but PgR negative in the corresponding biopsy samples suggest a greater proportion of malignant cells to be obtained with FNA than in surgical biopsy. In another breast cancer series (n = 50), corresponding comparisons for DNA flow cytometry showed concordance in ploidy status (diploid vs. non-diploid) in 84% of cases and a strong correlation in S-phase fraction values (r(s) = 0.70). At DNA image cytometry, concordant results (Auer I + II vs. Auer III + IV) were obtained in 87% of the cases. To sum up, FNA seems to be a useful sampling technique for PgR determination and DNA cytometry.
The introduction of titanium and its alloys in dental medicine highlighted various technological problems. Titanium and its alloys metallurgy is extremely difficult and thorough due to its chemical ...reactivity as well as the difficult conditions of processing. However, after 1980, the titanium and its alloys melting and casting technology have been improved continuously, very important facilities being currently available. Thus, in this paper we tried to bring into question a number of applications of metallurgy titanium and its alloys in dentistry, focusing in particular on this subspecialty, namely oral implantology.
On the Secure Sharing of Legacy Data Russell, D.; Power, D.; Slaymaker, M. ...
2009 Sixth International Conference on Information Technology: New Generations,
2009-April
Conference Proceeding
We describe a framework for the secure sharing and aggregation of legacy data. The framework, sif (for service-oriented interoperability framework), has two key principles at its core: that it should ...be possible to expose data from any legacy data source, irrespective of the underlying technologies or data models, and that data owners should be afforded the opportunity for expressive access control policies. sif abstracts issues such as secure transport and heterogeneous federation from application developers via a Java API. Our particular focus in this paper is sif's plug-in mechanism, which gives rise to a simple and elegant means of facilitating interoperability.
Objectif : Les mécanismes de toxicité et de génotoxicité induits par la Para-phénylèneDiamine (p-PD), un composant de la teinture pour cheveux suspecté d’être carcinogène, sur des cellules tumorales ...murines, type P3X63Ag8.653 ont été étudiés. Méthodes : L’effet de la p-PD sur la viabilité et celui sur la prolifération cellulaire ont été évalués par la méthode d’exclusion du bleu de trypan. Son effet sur l’ADN des cellules P3X63Ag8.653 a été analysé après une extraction d’ADN et une électrophorèse sur gel d’agarose puis confirmé par la technique TUNEL en cytométrie en flux. Résultats : Un blocage de la prolifération avec diminution de la viabilité cellulaire ont été observés. La fragmentation de l’ADN dose-dépendante témoignant de l’effet apoptotique a été détectée sur gel d’agarose et confirmée par cytométrie en flux (technique TUNEL). Conclusion : Les résultats obtenus montrent que la p-PD induit in vitro un blocage de la prolifération cellulaire et une apoptose dose-dépendante des cellules tumorales murines.
Aims: The mechanism of toxicity and genotoxicity of p-Phenylenediamine (p-PD), a component of human permanent hair dye and suspected to be a carcinogen, on the growth of murine tumor cells (P3X63Ag8.653) was investigated. Methods: The effect of p-PD on cell viability and proliferation was evaluated by the trypan blue exclusion method. The effect on the P3X63Ag8.653 cell DNA was analyzed by gel electrophoresis and confirmed by flow cytometry analysis (TUNEL technique). Results: A dose-dependent DNA fragmentation analyzed by gel electrophoresis shows a strong correlation with the flow cytometry analysis (TUNEL technique), suggesting that the effect of p-PD on overall viability and proliferation is mediated by DNA damage and an increase in apoptosis. Conclusion: The results suggest that the effect of p-PD on overall viability and proliferation of murine tumor cells is mediated by DNA damage and an increase in apoptosis in a dose-dependent manner.
RBS analysis of Au/Cr contact on GaAs Pantelica, D.; Drafta, G.; Borcan, C. ...
1996 International Semiconductor Conference. 19th Edition. CAS'96 Proceedings,
1996, Letnik:
2
Conference Proceeding
This paper investigates the mass transport in Au/Cr contacts deposited on GaAs. Such contacts are commonly used as ohmic contacts on p-type GaAs. For characterisation we used the RBS technique, ...replacing the classical /spl alpha/ particles with /sup 7/Li ions. This allows a great improvement in depth and mass resolution.
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