Context.
Thanks to the relative ease of finding and characterizing small planets around M-dwarf stars, these objects have become cornerstones in the field of exoplanet studies. The current paucity of ...planets in long-period orbits around M dwarfs makes such objects particularly compelling as they provide clues about the formation and evolution of these systems.
Aims.
In this study we present the discovery of TOI-2257 b (TIC 198485881), a long-period (35 d) sub-Neptune orbiting an M3 star at 57.8 pc. Its transit depth is about 0.4%, large enough to be detected with medium-size, ground-based telescopes. The long transit duration suggests the planet is in a highly eccentric orbit (
e
~ 0.5), which would make it the most eccentric planet known to be transiting an M-dwarf star.
Methods.
We combined TESS and ground-based data obtained with the 1.0-meter SAINT-EX, 0.60-meter TRAPPIST-North, and 1.2-meter FLWO telescopes to find a planetary size of 2.2
R
⊕
and an orbital period of 35.19 days. In addition, we make use of archival data, high-resolution imaging, and vetting packages to support our planetary interpretation.
Results.
With its long period and high eccentricity, TOI-2257 b falls into a novel slice of parameter space. Despite the planet’s low equilibrium temperature (~256 K), its host star’s small size (
R
*
= 0.311 ± 0.015) and relative infrared brightness (
K
mag
= 10.7) make it a suitable candidate for atmospheric exploration via transmission spectroscopy.
Sialic acids (Sias) are a class of sugar molecules with a parent nine-carbon neuraminic acid, generally present at the ends of carbohydrate chains, either attached to cellular surfaces or as secreted ...glycoconjugates. Given their position and structural diversity, Sias modulate a wide variety of biological processes. However, little is known about the role of Sias in human adipose tissue, or their implications for health and disease, particularly among individuals following different dietary patterns. The goal of this study was to measure N-Acetylneuraminic acid (Neu5Ac), N-Glycolylneuraminic acid (Neu5Gc), and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN) concentrations in adipose tissue samples from participants in the Adventist Health Study-2 (AHS-2) and to compare the abundance of these Sias in individuals following habitual, long-term vegetarian or non-vegetarian dietary patterns. A method was successfully developed for the extraction and detection of Sias in adipose tissue. Sias levels were quantified in 52 vegans, 56 lacto-vegetarians, and 48 non-vegetarians using LC-MS/MS with Neu5Ac-D-1,2,3-
C
as an internal standard. Dietary groups were compared using linear regression. Vegans and lacto-ovo-vegetarians had significantly higher concentrations of Neu5Ac relative to non-vegetarians. While KDN levels tended to be higher in vegans and lacto-ovo-vegetarians, these differences were not statistically significant. However, KDN levels were significantly inversely associated with body mass index. In contrast, Neu5Gc was not detected in human adipose samples. It is plausible that different Neu5Ac concentrations in adipose tissues of vegetarians, compared to those of non-vegetarians, reflect a difference in the baseline inflammatory status between the two groups. Epidemiologic studies examining levels of Sias in human adipose tissue and other biospecimens will help to further explore their roles in development and progression of inflammatory conditions and chronic diseases.
This article deals with the vector control in dq axes of a three-phase grid-connected photovoltaic system with single-stage topology and low-voltage-ride-through capability. The photovoltaic ...generator is built using an array of several series-parallel Suntech PV modules and is modeled as a Lookup Table (two-dimensional; 2-D). The requirements adopted when grid voltage sags occur are based in both the IEC 61400-21 European normative and the allowed amount of reactive power to be delivered according to the Spanish grid code, which avoids the disconnection of the inverter under grid faults by a limitation in the magnitude of the three-phase output inverter currents. For this, the calculation of the positive- and negative-sequences of the grid voltages is made and a conventional three-phase Phase-Locked Loop is used for the inverter-grid synchronization, allowing the control of the active and reactive powers solely with the dq components of the inverter currents. A detailed enhanced flowchart of the control algorithm with low-voltage-ride-through capability is presented and several simulations and experiments using Matlab/SIMULINK and the Controller Hardware-in-the-Loop simulation technique, respectively, are run for several types of one- and three-phase voltage sags in order to validate its behavior.
•An adaptive-frequency Harmonic-Compensation structure is used.•The frequency spectrum of the grid current is analyzed for different scenarios.•A comparison with the normative of the harmonic ...distortions is carried out.•The algorithms can be used in any country regardless its nominal frequency.
In this paper, an adaptive-frequency Harmonic-Compensation structure for a Voltage Source Inverter used in a 3-phase grid-connected Photovoltaic system is presented. The main purpose is to show the frequency adaptation of the used control algorithm in order to improve the compensation of the low-order utility grid current harmonics when frequency variations occur, which can be seen as an outstanding feature when comparing to conventional non-adaptive Harmonic-Compensator structures, and can be used in any country regardless its nominal frequency and maintaining its Harmonic Compensation capability without making any change in the control algorithm.
The frequency spectrum of the utility grid current is analyzed for three different scenarios: Proportional Resonant Controller without Harmonic Compensation, Proportional Resonant Controller with Harmonic Compensation, and adaptive-frequency Proportional Resonant Controller with Harmonic Compensation; a comparison with the normative of its individual and total harmonic amplitude distortions is carried out for the three situations.
In order to validate the algorithms, some simulations using MATLAB/SIMULINK from The MathWorks, Inc. are shown firstly, and secondly, some real-time digital simulations are carried out.
Abstract Several studies have shown circadian variations in the response of the immune system suggesting a role of the suprachiasmatic nucleus (SCN). Here we show that lipopolysaccharide (LPS) ...administration in the beginning of the active period induced more severe responses in temperature and cytokines than LPS given in the rest period. Moreover night administered LPS increased SCN basal neuronal activity indicating a direct influence of inflammation on the SCN. Bilateral lesions of the SCN resulted in an increased inflammatory response to LPS demonstrating that an interaction between the SCN and the immune system modulates the intensity of the inflammatory response.
We report the discovery of a hot Jupiter on a 3.28-day orbit around a 1.08
M
⊙
G0 star that is the secondary component in a loose binary system. Based on follow-up radial velocity observations of ...TOI-858 B with CORALIE on the Swiss 1.2 m telescope and CHIRON on the 1.5 m telescope at the Cerro Tololo Inter-American Observatory (CTIO), we measured the planet mass to be 1.10
−0.07
+0.08
M
J
. Two transits were further observed with CORALIE to determine the alignment of TOI-858 B b with respect to its host star. Analysis of the Rossiter-McLaughlin signal from the planet shows that the sky-projected obliquity is
λ
= 99.3
−3.7
+3.8°
. Numerical simulations show that the neighbour star TOI-858 A is too distant to have trapped the planet in a Kozai–Lidov resonance, suggesting a different dynamical evolution or a primordial origin to explain this misalignment. The 1.15
M
⊙
primary F9 star of the system (TYC 8501-01597-1, at
ρ
~11″) was also observed with CORALIE in order to provide upper limits for the presence of aplanetary companion orbiting that star.
Multi-port beam splitters are cornerstone devices for high-dimensional quantum information tasks, which can outperform the two-dimensional ones. Nonetheless, the fabrication of such devices has ...proven to be challenging with progress only recently achieved with the advent of integrated photonics. Here, we report on the production of high-quality N × N (with N = 4 , 7 ) multi-port beam splitters based on a new scheme for manipulating multi-core optical fibers. By exploring their compatibility with optical fiber components, we create four-dimensional quantum systems and implement the measurement-device-independent random number generation task with a programmable four-arm interferometer operating at a 2 MHz repetition rate. Due to the high visibilities observed, we surpass the one-bit limit of binary protocols and attain 1.23 bits of certified private randomness per experimental round. Our result demonstrates that fast switching, low loss, and high optical quality for high-dimensional quantum information can be simultaneously achieved with multi-core fiber technology.
This work proposes a Double Differential (DD) amplifier topology which exploits the advantages of the current-mode approach. DD amplifiers are useful as front-ends in standalone active electrodes for ...superficial electromyography (sEMG) wearable applications and electroneurography (ENG) measurement devices. Front-ends for these applications need to attain low noise, high common-mode rejection ratio, and high input impedance to measure biopotential signals and can further benefit from low power operation, a small size, and an easily adaptable output. Presently published DD amplifiers are either complex in terms of a high part count, leading to higher power consumption and size, or suffer from limited interference-rejection capabilities and require further analog processing for compatibility with single-ended systems. Therefore, in this work, second-generation current conveyors have been leveraged to obtain a simple topology combining a small active-part count, a high common-mode rejection ratio, and a flexible output stage. The current-mode DD amplifier is presented and analyzed in detail to estimate its parameters and model the effects of nonidealities in the circuit. In order to validate the proposed topology, a discrete-component implementation was realized as a proof-of-concept. The results experimentally demonstrated the properties of the proposed topology and its feasibility for measuring superficial sEMG DD signals.
We report the characterization of two planet candidates detected by the Transiting Exoplanet Survey Satellite (TESS), TOI-1199 b and TOI-1273 b, with periods of 3.7 and 4.6 days, respectively. ...Follow-up observations for both targets, which include several ground-based light curves, confirmed the transit events. High-precision radial velocities from the SOPHIE spectrograph revealed signals at the expected frequencies and phases of the transiting candidates and allowed mass determinations with a precision of 8.4% and 6.7% for TOI-1199 b and TOI-1273 b, respectively. The planetary and orbital parameters were derived from a joint analysis of the radial velocities and photometric data. We find that the planets have masses of 0.239 ± 0.020 M J and 0.222 ± 0.015 M J and radii of 0.938 ± 0.025 R J and 0.99 ± 0.22 R J , respectively. The grazing transit of TOI-1273 b translates to a larger uncertainty in its radius, and hence also in its bulk density, compared to TOI-1199 b. The inferred bulk densities of 0.358 ± 0.041 g cm −3 and 0.28 ± 0.11 g cm −3 are among the lowest known for exoplanets in this mass range, which, considering the brightness of the host stars ( V ≈11 mag), render them particularly amenable to atmospheric characterization via the transit spectroscopy technique. The better constraints on the parameters of TOI-1199 b provide a transmission spectroscopy metric of 134 ± 17, making it the better suited of the two planets for atmospheric studies.
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