We proposed a model of intergroup contact wherein contact promotes understanding of outgroup perspectives, perspective taking relates to reduced intergroup anxiety that in turn is associated with ...lessened stereotyping and more positive intergroup attitudes. Additionally, we examined if implicit attitudes followed this model or were directly impacted by contact. White undergraduates (n = 153) completed measures of contact, perspective taking, intergroup anxiety, stereotype endorsement, and implicit and explicit intergroup attitudes. Our model fitted the data well but explained explicit attitudes and stereotyping better than implicit attitudes. Supporting an environmental association interpretation, contact was the only significant predictor of implicit attitudes. Findings support a dual-process model wherein implicit and explicit attitudes represent separate constructs and support the value of contact in improving intergroup attitudes.
Two hundred seventy‐three White undergraduates participated in an investigation of how beliefs relate to support for affirmative action (AA) policies. Beliefs included belief in the fairness of AA, ...belief in merit, and belief in the value of diversity. Analyses predicted support for a general affirmative action policy, a tiebreak policy, and a policy using banding from beliefs and individual‐level variables such as future benefit from AA and demographics. For the general policy, each belief predicted support for AA. Fairness and value of diversity predicted support for a tiebreak policy. Value of diversity predicted support for aptitude testing. Individual characteristics improved prediction for AA in general but not for tiebreak policy or aptitude testing. We discuss predictions and results in terms of procedural and distributive justice, fairness heuristic theory, and models of support for AA.
Supergenes are tight clusters of loci that facilitate the co-segregation of adaptive variation, providing integrated control of complex adaptive phenotypes. Polymorphic supergenes, in which specific ...combinations of traits are maintained within a single population, were first described for 'pin' and 'thrum' floral types in Primula and Fagopyrum, but classic examples are also found in insect mimicry and snail morphology. Understanding the evolutionary mechanisms that generate these co-adapted gene sets, as well as the mode of limiting the production of unfit recombinant forms, remains a substantial challenge. Here we show that individual wing-pattern morphs in the polymorphic mimetic butterfly Heliconius numata are associated with different genomic rearrangements at the supergene locus P. These rearrangements tighten the genetic linkage between at least two colour-pattern loci that are known to recombine in closely related species, with complete suppression of recombination being observed in experimental crosses across a 400-kilobase interval containing at least 18 genes. In natural populations, notable patterns of linkage disequilibrium (LD) are observed across the entire P region. The resulting divergent haplotype clades and inversion breakpoints are found in complete association with wing-pattern morphs. Our results indicate that allelic combinations at known wing-patterning loci have become locked together in a polymorphic rearrangement at the P locus, forming a supergene that acts as a simple switch between complex adaptive phenotypes found in sympatry. These findings highlight how genomic rearrangements can have a central role in the coexistence of adaptive phenotypes involving several genes acting in concert, by locally limiting recombination and gene flow.
Could co-teaching be a mechanism to support the adoption of evidence-based teaching strategies? Co-teaching has been proposed as a lever for fostering pedagogical change and has key attributes of a ...successful change strategy, but does research indicate co-teaching effectively shifts instructional practices? Based on our review of the emerging evidence, we wrote this essay for multiple audiences, including science, technology, engineering, and mathematics (STEM) instructors, education development professionals, leaders who oversee teaching, and researchers. We define co-teaching in the context of STEM higher education and summarize what is known about the pedagogical changes that co-teaching could support and the potential mechanisms behind these changes. We share recommendations based on the available evidence for those who need productive ideas right now. We also lay out a variety of future directions for research about co-teaching as a lever for pedagogical change. Achieving widespread and impactful pedagogical change is a monumental undertaking facing STEM higher education, and multiple approaches will be needed to meet this challenge. Co-teaching has potential to shift ways of thinking and pedagogical practices among undergraduate STEM faculty, but how co-teaching is enacted is likely crucial to its impact, as is the context in which it occurs.
BackgroundPrevious research suggests that mindfulness training (MT) appears effective at improving mental health in young people. MT is proposed to work through improving executive control in ...affectively laden contexts. However, it is unclear whether MT improves such control in young people. MT appears to mitigate mental health difficulties during periods of stress, but any mitigating effects against COVID-related difficulties remain unexamined.ObjectiveTo evaluate whether MT (intervention) versus psychoeducation (Psy-Ed; control), implemented in after-school classes: (1) Improves affective executive control; and/or (2) Mitigates negative mental health impacts from the COVID-19 pandemic.MethodsA parallel randomised controlled trial (RCT) was conducted (Registration: https://osf.io/d6y9q/; Funding: Wellcome (WT104908/Z/14/Z, WT107496/Z/15/Z)). 460 students aged 11-16 years were recruited and randomised 1:1 to either MT (N=235) or Psy-Ed (N=225) and assessed preintervention and postintervention on experimental tasks and self-report inventories of affective executive control. The RCT was then extended to evaluate protective functions of MT on mental health assessed after the first UK COVID-19 lockdown.FindingsResults provided no evidence that the version of MT used here improved affective executive control after training or mitigated negative consequences on mental health of the COVID-19 pandemic relative to Psy-Ed. No adverse events were reported.ConclusionsThere is no evidence that MT improves affective control or downstream mental health of young people during stressful periods.Clinical implicationsWe need to identify interventions that can enhance affective control and thereby young people’s mental health.
Projectile components that are traditionally radiolucent can be of considerable importance in determination of weapon type and caliber, but they are often missed on evaluation of postmortem ...radiographs. We hypothesized that these components would be significantly better visualized by evaluation of computed tomography (CT) scans compared to the practice standard of radiography alone. In this project, potentially radiolucent projectile components were both pulled apart and fired, and the radiolucent components were recovered. These components were embedded in blocks of ballistics gelatin and were imaged using both radiography and CT. The scans were evaluated by three blinded, board‐certified radiologists for the presence/absence of projectile components and true‐negative regions in each block. If a radiologist indicated visualization of a projectile component, they were further requested to describe their observation. It was found that traditionally radiolucent projectile components are not significantly more often identified on CT scans than radiography (p < 0.05).
Provider: - Institution: - Data provided by Europeana Collections- We proposed a model of intergroup contact wherein contact promotes understanding of outgroup perspectives, perspective taking ...relates to reduced intergroup anxiety that in turn is associated with lessened stereotyping and more positive intergroup attitudes. Additionally, we examined if implicit attitudes followed this model or were directly impacted by contact. White undergraduates (n = 153) completed measures of contact, perspective taking, intergroup anxiety, stereotype endorsement, and implicit and explicit intergroup attitudes. Our model fitted the data well but explained explicit attitudes and stereotyping better than implicit attitudes. Supporting an environmental association interpretation, contact was the only significant predictor of implicit attitudes. Findings support a dual-process model wherein implicit and explicit attitudes represent separate constructs and support the value of contact in improving intergroup attitudes.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
ART4 (CD297) is a member of the family of toxin-related ADP-ribosyltransferases (ARTs) and is the carrier of the Dombrock blood group alloantigens (Do). Two mouse monoclonal antibodies (MIMA-52 and ...MIMA-53), and two rat monoclonal antibodies (N0NI-B4 and NONI-B63) were obtained following immunization of mice with human Do/ART4-transfected cells and of rats with human Do/ART4 cDNA, respectively. All four mAbs recognize Do/ART4-transfected Jurkat cells but not untransfected cells by FACS analysis. Staining of Do/ART4-transfected cells by these mAbs was reduced following treatment of cells with PI-PLC, confirming that Do/ART4 is anchored in the cell membrane by linkage to glycosylphosphatidylinositol as predicted from its amino acid sequence. The four mAbs did not react with Gy(a−) (Dombrock null) erythrocytes but agglutinated other red blood cells. By flow cytometric analysis, all mAbs reacted prominently with erythrocytes, and weakly with peripheral blood monocytes and splenic macrophages, but not with B-lymphocytes or T-lymphocytes. The mAbs reacted weakly also with human umbilical vein endothelial cells and the basophilic leukemia KU-812. Immunohistology revealed staining of epithelia and endothelia on sections of tonsils. In FACS analyses NONI-B4 competed with MIMA-52 for binding to Do/ART4-transfected cells and erythrocytes, whereas NONI-B63 competed with MIMA-53. Neither of the mAbs reacted with mouse ART4-transfected cells, but NONI-B63 and MIMA-53 did react with a mouse/human ART4 chimera, indicating that the epitope recognized by these mAbs lies in the C-terminal half of the protein.
PDF
