Candelilla wax (CW) is a natural plant wax derived from Euphorbia antisyphilitica Zucc., which is grown in the arid regions of northern Mexico. Notably, CW has emerged as a promising potential ...substance for use in the development of food formulations. This review provides insights into the most suitable and promising applications of CW. We specifically focus on the main wax-based formulations designed for the food industry with a particular emphasis on their properties. The field of CW research has evidenced that the physicochemical and functional properties of this wax mean that it is suitable for use in a wide range of food applications with desirable characteristics, including, but not limited to, CW-based emulsions, edible films and coatings, oleogels, among others. Furthermore, as a food additive, CW application may guarantee safe and high-quality foods. Therefore, these innovations clearly illustrate that CW can be of great value within the food field, thus potentializing its usage.
•Candelilla wax (CW) is the most commercially important wax in northern Mexico.•CW has potential functionality as a constituent of different food formulations.•Edible packaging and oleogels are feasible in the development of high-quality foods.•CW-based food products have similar technological properties to reference products.
Las cartas son un ejercicio pedagógico realizado con estudiantes y sus familias durante el aprendizaje en casa. Es una propuesta que busca llegar a las familias de los estudiantes, para animarlos y ...ofrecerles salidas, desde la lectura y la escritura, a la crisis psicosocial que los afecta. Contienen mensajes elaborados por varios maestros y mensajes emitidos por estudiantes y padres de familia de manera escrita, gráfica y en pódcast. El propósito es hacer reconocer los aprendizajes de los estudiantes en la sindemia para que los haga suyos la escuela.
To determine the efficacy of the "interpersonal influence intervention" conducted by health professionals to increase the commitment to adopt health-promoting behavior in nursing students compared to ...the usual care of a university wellness program.
A quasi-experimental study was performed. The study included 114 nursing students from a university in Cali, Colombia, who were divided into a control group (n = 57) that received usual care and an experimental group (n = 57) that received the intervention designed and validated according to Nola Pender's Health Promotion Model. The main outcome was the lifestyle measured before and after the test using the Health-Promoting Lifestyle Profile II Spanish version. The effect of the intervention was carried out through the average comparison, effect size measures were calculated using Cohen's d and analysis of the effect of possible confounding variables on the intervention (ANCOVA).
A statistically significant difference was observed between the experimental group and the control group (p = 0.015; 95% CI -0.42, -0.05). The effect size of the intervention was 0.49. The interpersonal influences exhibited by health professionals can increase the commitment to adopt health-promoting behaviors (Hypothesis 1), and the greater the commitment to a specific action plan, the more likely it is that health-promoting behaviors will be maintained over time (Hypothesis 2).
The effectiveness of the intervention interpersonal influences exerted by health professionals to increase the commitment to adopt health-promoting behavior is proven. Evidence demonstrates the practical utility of the Health Promotion Model.
Summary
The combination of fludarabine, cytarabine, idarubicin, and granulocyte colony‐stimulating factor (FLAG‐Ida) is widely used in relapsed/refractory acute myeloid leukaemia (AML). We ...retrospectively analysed the results of 259 adult AML patients treated as first salvage with FLAG‐Ida or FLAG‐Ida plus Gentuzumab‐Ozogamicin (FLAGO‐Ida) of the Programa Español de Tratamientos en Hematología (PETHEMA) database, developing a prognostic score system of survival in this setting (SALFLAGE score). Overall, 221 patients received FLAG‐Ida and 38 FLAGO‐Ida; 92 were older than 60 years. The complete remission (CR)/CR with incomplete blood count recovery (CRi) rate was 51%, with 9% of induction deaths. Three covariates were associated with lower CR/CRi: high‐risk cytogenetics and t(8;21) at diagnosis, no previous allogeneic stem cell transplantation (allo‐SCT) and relapse‐free interval <1 year. Allo‐SCT was performed in second CR in 60 patients (23%). The median overall survival (OS) of the entire cohort was 0·7 years, with 22% OS at 5‐years. Four independent variables were used to construct the score: cytogenetics, FLT3‐internal tandem duplication, length of relapse‐free interval and previous allo‐SCT. Using this stratification system, three groups were defined: favourable (26% of patients), intermediate (29%) and poor‐risk (45%), with an expected 5‐year OS of 52%, 26% and 7%, respectively. The SALFLAGE score discriminated a subset of patients with an acceptable long‐term outcome using FLAG‐Ida/FLAGO‐Ida regimen. The results of this retrospective analysis should be validated in independent external cohorts.
SARS-CoV-2 (COVID-19) has caused over 80 million infections 973,000 deaths in the United States, and mutations are linked to increased transmissibility. This study aimed to determine the effect of ...SARS-CoV-2 variants on respiratory features, mortality, and to determine the effect of vaccination status. A retrospective review of medical records (n = 55,406 unique patients) using the University of California Health COvid Research Data Set (UC CORDS) was performed to identify respiratory features, vaccination status, and mortality from 01/01/2020 to 04/26/2022. Variants were identified using the CDC data tracker. Increased odds of death were observed amongst unvaccinated individuals and fully vaccinated, partially vaccinated, or individuals who received any vaccination during multiple waves of the pandemic. Vaccination status was associated with survival and a decreased frequency of many respiratory features. More recent SARS-CoV-2 variants show a reduction in lower respiratory tract features with an increase in upper respiratory tract features. Being fully vaccinated results in fewer respiratory features and higher odds of survival, supporting vaccination in preventing morbidity and mortality from COVID-19.
La implementación de la política de planificación del Ecuador alcanzó una etapa importante en la reorganización territorial en el periodo 2007-2017. El objetivo de este documento es discutir el ...fortalecimiento de las ciudades intermedias como uno de los principales efectos de esta política. Para ello, primero se realiza un breve análisis del proceso histórico de la urbanización ecuatoriana, que muestra las dificultades causadas por la constitución de una red urbana vertical con pocas ciudades medianas. Luego, se analiza cómo los planes de descentralización y las medidas de desconcentración implementadas por la política de planificación nacional contribuyeron a reforzar la posición de Milagro en la red urbana del Ecuador. Por último, en las consideraciones finales, se señalan las contribuciones relevantes de la planificación estatal para fortalecer la red urbana en Ecuador.
La investigación realizada presentó como centro de interés el aprendizaje de la multiplicación, a partir de la implementación de una estrategia didáctica, aplicada a niños de grado tercero de Básica ...Primaria. Se tuvo en cuenta que para los niños es de vital importancia ser protagonistas de su propio conocimiento, es decir, cuando ellos se sienten involucrados en el diseño de las estrategias, se sienten motivados por el aprendizaje que viene en camino. El propósito estuvo enfocado a implementar estrategias pedagógicas mediadas por la lúdica, el juego y la cotidianidad, para contribuir en el aprendizaje de la multiplicación de los estudiantes del grado tercero de educación básica de la Institución Educativa Julius Sieber de la ciudad de Tunja. La metodología implementada estuvo enfocada en lo cualitativo, con tipo investigación acción, con el desarrollo de cuatro fases. Entre los resultados se percibe que, los niños se divirtieron con la estrategia, debido a la motivación que tuvieron con el uso del computador; los que tenían acceso a esta herramienta. Los que desarrollaron la estrategia en el cuaderno, se divirtieron, porque las situaciones problema enunciadas hicieron parte de su cotidianidad; en el mismo sentido, la reflexión docente acerca del proceso de elaboración, aplicación y reflexión de la estrategia, por parte del docente, enriquece los procesos.
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