An Essay on Names and Truth Hinzen, W; Kjøll, G
Journal of Linguistics,
03/2009, Letnik:
45, Številka:
1
Book Review
Recenzirano
An essay on names and truth stands out as a daring project which poses a major challenge to all exponents of externalism, defenders of the Language of Thought hypothesis, non-atomistic internalists, ...and generative grammarians who want to preserve the autonomy of syntax. It is, all in all, a well-structured, well-written book that succeeds in putting all the fundamental issues for a theory of meaning on the table, and as such it cannot be ignored either by opponents to Hinzen's approach or by those who are curious about the scope and limitations of syntax-driven theories of meaning.
Here we show that a new class of antibiotics-acyldepsipeptides-has antibacterial activity against Gram-positive bacteria in vitro and in several rodent models of bacterial infection. The ...acyldepsipeptides are active against isolates that are resistant to antibiotics in clinical application, implying a new target, which we identify as ClpP, the core unit of a major bacterial protease complex. ClpP is usually tightly regulated and strictly requires a member of the family of Clp-ATPases and often further accessory proteins for proteolytic activation. Binding of acyldepsipeptides to ClpP eliminates these safeguards. The acyldepsipeptide-activated ClpP core is capable of proteolytic degradation in the absence of the regulatory Clp-ATPases. Such uncontrolled proteolysis leads to inhibition of bacterial cell division and eventually cell death.
For more than ten years researchers have concentrated on the development as well as on the mechanical properties of textile reinforced concrete. The tensile load bearing behavior of this new ...composite material is generally determined with tensile specimens in most different ways. The variety of specimens and test configurations lead however to the fact that results are not always comparable. Moreover, own results with uncoated AR-glass textiles showed relatively high scattering in the past. Some influences on the load bearing behavior could already be clarified. However, many questions are still unanswered. Therefore, it is the scope of this paper to investigate a set of influencing factors with regard to the first crack strength and the load bearing behavior of textile reinforced concrete. The investigated parameters include the alignment of the textile reinforcement, the moisture content of the specimens during testing and in some cases the specimen shape. Special attention was given to the repeatability of the results.