In this work we investigate the minimal physical requirements needed for generating a speed of sound that surpasses its asymptotic conformal limit. It is shown that a peak in the speed of sound of ...homogeneous matter naturally emerges in the transition from a phase with broken chiral symmetry to one with a gapped Fermi surface. We argue that this could be relevant for understanding the peak in the speed of sound displayed by some of the current models for cold ultradense matter. A minimal model implementation of this mechanism is presented, based on the spontaneous breakdown of an approximate particle-antiparticle symmetry, and its thermodynamic properties are determined.
Statistical moments of particle multiplicities in heavy-ion collision experiments are an important probe in the exploration of the phase diagram of strongly interacting matter and, particularly, in ...the search for the QCD critical end point. In order to appropriately interpret experimental measures of these moments, however, it is necessary to understand the role of experimental limitations, as well as background contributions, providing expectations on how critical behavior should be affected by them. We here present a framework for calculating moments of particle multiplicities in the presence of correlations of both critical and spurious origins. We also include effects from resonance decay and a limited acceptance window, as well as detector efficiency. Although we focus on second-order moments, for simplicity, an extension to higher-order moments is straightforward.
Autophagy in cancer: good, bad, or both? Hippert, Melanie M; O'Toole, Patrick S; Thorburn, Andrew
Cancer research (Chicago, Ill.),
10/2006, Letnik:
66, Številka:
19
Journal Article
Recenzirano
Autophagy has been recognized as an important cellular process for at least 50 years; however, it is only with the recent identification of key regulators of autophagy (Atg genes) that we have begun ...a mechanistic exploration of its importance in cancer. Recent studies suggest that autophagy may be important in the regulation of cancer development and progression and in determining the response of tumor cells to anticancer therapy. However, the role of autophagy in these processes is complicated and may, depending on the circumstances, have diametrically opposite consequences for the tumor. In this article, we discuss recent discoveries regarding autophagy in cancer.
New class of compact stars: Pion stars Brandt, B. B.; Endrődi, G.; Fraga, E. S. ...
Physical review. D,
11/2018, Letnik:
98, Številka:
9
Journal Article
Recenzirano
Odprti dostop
We investigate the viability of a new type of compact star whose main constituent is a Bose-Einstein condensate of charged pions. Several different setups are considered, where a gas of charged ...leptons and neutrinos is also present. The pionic equation of state is obtained from lattice QCD simulations in the presence of an isospin chemical potential and requires no modeling of the nuclear force. The gravitationally bound configurations of these systems are found by solving the Tolman-Oppenheimer-Volkoff equations. We discuss weak decays within the pion condensed phase and elaborate on the generation mechanism of such objects.
The neighborhood of the QCD chiral critical point is characterized by intense fluctuations of the chiral field which could, in principle, generate pronounced experimental signatures. However, ...experimental uncertainties which are inherent to heavy-ion collisions, as well as the modest size and duration of the formed plasma, will severely attenuate these signatures. Using Monte Carlo techniques, we study second-order event-by-event moments of pions as a prototype for signatures of the chiral critical point based on the enhancement of the correlation length and event-by-event analysis. We test their viability against some realistic ingredients, similar to the ones found in the RHIC beam energy scan program.
Pions near the chiral critical point Hippert, M; S Fraga, E; Santos, E M
Journal of physics. Conference series,
04/2016, Letnik:
706, Številka:
5
Journal Article
Recenzirano
Odprti dostop
It is an exciting possibility that the QCD critical point can be found in ultrarelativistic heavy-ion collision experiments (HICs). While quantities such as some event-by-event moments of specific ...observables should display strong non-monotonic behavior near the critical point and could, hence, be used as signatures of criticality, it is not clear that this behavior could effectively be observed in the highly non-ideal scenario of HICs. We here employ Monte Carlo simulations to test second-order moments of pion observables as possible signatures of the critical point while taking into account some realistic ingredients, similar to the ones found in HICs. We make use of simplified models to introduce spurious contributions and dynamical effects.
We investigate the effects of prehydrodynamic evolution on final-state observables in heavy-ion collisions using state-of-the art event simulations coupled to different prehydrodynamic scenarios, ...which include the recently developed effective kinetic transport theory evolution model KøMPøST. Differential flow observables are found to be mostly insensitive to the details of prehydrodynamic evolution. The main effect we observe is in the pT spectra, particularly the mean transverse momentum. However, at least part of this effect is a consequence of the underlying conformal invariance assumption currently present in such approaches, which is known to be violated in the temperature regime probed in heavy-ion collisions. This assumption of early time conformal invariance leads to an artificially large out-of-equilibrium bulk pressure when switching from (conformal) prehydrodynamic evolution to hydrodynamics (using the nonconformal QCD equation of state), which in turn increases the transverse momentum. Our study indicates that a consistent treatment of prehydrodynamic evolution in heavy-ion collisions requires the use of nonconformal models of early time dynamics.
An outstanding problem in heavy-ion collisions is the inability for models to accurately describe ultra-central experimental flow data, despite that being precisely the regime where a hydrodynamic ...description should be most applicable. Here, we reassess the status of this puzzle by computing the flow in ultra-central collisions obtained from multiple recent Bayesian models that were tuned to various observables in different collision systems at typical centralities. While central data can now be described with better accuracy than in previous calculations, tension with experimental observation remains and worsens as one goes to ultra-central collisions. Tuning the model parameters cannot remove this tension without destroying the fit at other centralities. As such, new elements are likely needed in the standard modeling of heavy-ion collisions.