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zadetkov: 436
1.
  • High-throughput screening o... High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells
    Zhou, Yuexin; Zhu, Shiyou; Cai, Changzu ... Nature (London), 05/2014, Letnik: 509, Številka: 7501
    Journal Article
    Recenzirano

    Targeted genome editing technologies are powerful tools for studying biology and disease, and have a broad range of research applications. In contrast to the rapid development of toolkits to ...
Celotno besedilo
2.
  • Single-cell RNA-seq transcr... Single-cell RNA-seq transcriptome analysis of linear and circular RNAs in mouse preimplantation embryos
    Fan, Xiaoying; Zhang, Xiannian; Wu, Xinglong ... Genome Biology, 07/2015, Letnik: 16, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Circular RNAs (circRNAs) are a new class of non-polyadenylated non-coding RNAs that may play important roles in many biological processes. Here we develop a single-cell universal poly(A)-independent ...
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3.
  • Centrifugal micro-channel array droplet generation for highly parallel digital PCR
    Chen, Zitian; Liao, Peiyu; Zhang, Fangli ... Lab on a chip, 01/2017, Letnik: 17, Številka: 2
    Journal Article
    Recenzirano

    Stable water-in-oil emulsion is essential to digital PCR and many other bioanalytical reactions that employ droplets as microreactors. We developed a novel technology to produce monodisperse emulsion ...
Celotno besedilo
4.
  • Live-Cell Stimulated Raman ... Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules
    Hong, Senlian; Chen, Tao; Zhu, Yuntao ... Angewandte Chemie (International ed.), June 2, 2014, Letnik: 53, Številka: 23
    Journal Article
    Recenzirano

    Alkynes can be metabolically incorporated into biomolecules including nucleic acids, proteins, lipids, and glycans. In addition to the clickable chemical reactivity, alkynes possess a unique Raman ...
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5.
  • Single-cell triple omics se... Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas
    Hou, Yu; Guo, Huahu; Cao, Chen ... Cell research, 03/2016, Letnik: 26, Številka: 3
    Journal Article
    Recenzirano
    Odprti dostop

    Single-ceU genome, DNA methylome, and transcriptome sequencing methods have been separately developed. However, to accurately analyze the mechanism by which transcriptome, genome and DNA methylome ...
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6.
  • Study on Pain Catastrophizi... Study on Pain Catastrophizing From 2010 to 2020: A Bibliometric Analysis via CiteSpace
    Luo, Huifang; Cai, Zongliao; Huang, Yanyi ... Frontiers in psychology, 12/2021, Letnik: 12
    Journal Article
    Recenzirano
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    This study aimed to evaluate the global scientific output of research on pain catastrophizing and explore the hotspots and frontiers from 2010 to 2020 using bibliometric methods. Publications ...
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7.
  • Uniform and accurate single... Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification
    Fu, Yusi; Li, Chunmei; Lu, Sijia ... Proceedings of the National Academy of Sciences - PNAS, 09/2015, Letnik: 112, Številka: 38
    Journal Article
    Recenzirano
    Odprti dostop

    Whole-genome amplification (WGA) for next-generation sequencing has seen wide applications in biology and medicine when characterization of the genome of a single cell is required. High uniformity ...
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8.
  • Chemoproteomics reveals bai... Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
    Dai, Jianye; Liang, Kai; Zhao, Shan ... Proceedings of the National Academy of Sciences - PNAS, 06/2018, Letnik: 115, Številka: 26
    Journal Article
    Recenzirano
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    Obesity and related metabolic diseases are becoming worldwide epidemics that lead to increased death rates and heavy health care costs. Effective treatment options have not been found yet. Here, ...
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9.
  • A body map of somatic mutag... A body map of somatic mutagenesis in morphologically normal human tissues
    Li, Ruoyan; Di, Lin; Li, Jie ... Nature, 09/2021, Letnik: 597, Številka: 7876
    Journal Article
    Recenzirano
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    Somatic mutations that accumulate in normal tissues are associated with ageing and disease.sup.1,2. Here we performed a comprehensive genomic analysis of 1,737 morphologically normal tissue biopsies ...
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10.
  • Lactoferrin Alleviates Infl... Lactoferrin Alleviates Inflammation and Regulates Gut Microbiota Composition in H5N1-Infected Mice
    Huang, Yanyi; Zhang, Peiyang; Han, Shuyi ... Nutrients, 07/2023, Letnik: 15, Številka: 15
    Journal Article
    Recenzirano
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    The impact of lactoferrin, an antimicrobial peptide (AMP) with iron-binding properties, on the intestinal barrier and microflora of mice infected with highly pathogenic avian influenza A (H5N1) virus ...
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zadetkov: 436

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