Neutrino-induced coherent charged pion production on nuclei νμA→μ(±)π(∓)A is a rare, inelastic interaction in which a small squared four-momentum |t| is transferred to the recoil nucleus, leaving it ...intact in the reaction. In the scintillator tracker of MINERvA, we remove events with evidence of particles from nuclear breakup and reconstruct |t| from the final-state pion and muon. We select low |t| events to isolate a sample rich in coherent candidates. By selecting low |t| events, we produce a model-independent measurement of the differential cross section for coherent scattering of neutrinos and antineutrinos on carbon. We find poor agreement with the predicted kinematics in neutrino generators used by current oscillation experiments.
Neutrino induced coherent charged pion production on nuclei, ν¯μA→μ±π∓A, is a rare inelastic interaction in which the four-momentum squared transferred to the nucleus is nearly zero, leaving it ...intact. We identify such events in the scintillator of MINERvA by reconstructing |t| from the final state pion and muon momenta and by removing events with evidence of energetic nuclear recoil or production of other final state particles. We measure the total neutrino and antineutrino cross sections as a function of neutrino energy between 2 and 20 GeV and measure flux integrated differential cross sections as a function of Q2, Eπ, and θπ. The Q2 dependence and equality of the neutrino and antineutrino cross sections at finite Q2 provide a confirmation of Adler’s partial conservation of axial current hypothesis.
The MINERvA Collaboration reports a novel study of neutrino-nucleus charged-current deep inelastic scattering (DIS) using the same neutrino beam incident on targets of polystyrene, graphite, iron, ...and lead. Results are presented as ratios of C, Fe, and Pb to CH. The ratios of total DIS cross sections as a function of neutrino energy and flux-integrated differential cross sections as a function of the Bjorken scaling variable x are presented in the neutrino-energy range of 5-50 GeV. Based on the predictions of charged-lepton scattering ratios, good agreement is found between the data and prediction at medium x and low neutrino energy. However, the ratios appear to be below predictions in the vicinity of the nuclear shadowing region, x<0.1. This apparent deficit, reflected in the DIS cross-section ratio at high E sub(nu), is consistent with previous MINERvA observations B. Tice et al.(MINERvA Collaboration), Phys. Rev. Lett. 112, 231801 (2014). and with the predicted onset of nuclear shadowing with the axial-vector current in neutrino scattering.
The total cross sections are important ingredients for the current and future neutrino oscillation experiments. We present measurements of the total charged-current neutrino and antineutrino cross ...sections on scintillator (CH) in the NuMI low-energy beamline using an in situ prediction of the shape of the flux as a function of neutrino energy from 2–50 GeV. This flux prediction takes advantage of the fact that neutrino and antineutrino interactions with low nuclear recoil energy (ν) have a nearly constant cross section as a function of incident neutrino energy. This measurement is the lowest energy application of the low-ν flux technique, the first time it has been used in the NuMI antineutrino beam configuration, and demonstrates that the technique is applicable to future neutrino beams operating at multi-GeV energies. The cross section measurements presented are the most precise measurements to date below 5 GeV.
We studied single neutral pion production via muon antineutrino charged-current interactions in plastic scintillator (CH) using the MINERvA detector exposed to the NuMI low-energy, wideband ...antineutrino beam at Fermilab. Measurement of this process constrains models of neutral pion production in nuclei, which is important because the neutral-current analog is a background for appearance oscillation experiments. Furthermore, the differential cross sections for π0 momentum and production angle, for events with a single observed π0 and no charged pions, are presented and compared to model predictions. These results comprise the first measurement of the π0 kinematics for this process.
We present measurements of the neutrino and antineutrino total charged-current cross sections on carbon and their ratio using the MINERvA scintillator-tracker. The measurements span the energy range ...2–22 GeV and were performed using forward and reversed horn focusing modes of the Fermilab low-energy NuMI beam to obtain large neutrino and antineutrino samples. The flux is obtained using a subsample of charged-current events at low hadronic energy transfer along with precise higher energy external neutrino cross section data overlapping with our energy range between 12–22 GeV. We also report on the antineutrino-neutrino cross section ratio, RCC, which does not rely on external normalization information. Our ratio measurement, obtained within the same experiment using the same technique, benefits from the cancellation of common sample systematic uncertainties and reaches a precision of ∼5% at low energy. Our results for the antineutrino-nucleus scattering cross section and for RCC are the most precise to date in the energy range Eν<6 GeV.
We present measurements of ν(μ) charged-current cross section ratios on carbon, iron, and lead relative to a scintillator (CH) using the fine-grained MINERvA detector exposed to the NuMI neutrino ...beam at Fermilab. The measurements utilize events of energies 2<E(ν)<20 GeV, with ⟨E(ν)⟩ = 8 GeV, which have a reconstructed μ(-) scattering angle less than 17° to extract ratios of inclusive total cross sections as a function of neutrino energy E(ν) and flux-integrated differential cross sections with respect to the Bjorken scaling variable x. These results provide the first high-statistics direct measurements of nuclear effects in neutrino scattering using different targets in the same neutrino beam. Measured cross section ratios exhibit a relative depletion at low x and enhancement at large x. Both become more pronounced as the nucleon number of the target nucleus increases. The data are not reproduced by GENIE, a conventional neutrino-nucleus scattering simulation, or by the alternative models for the nuclear dependence of inelastic scattering that are considered.
Charged-current ν_{μ} interactions on carbon, iron, and lead with a final state hadronic system of one or more protons with zero mesons are used to investigate the influence of the nuclear ...environment on quasielasticlike interactions. The transferred four-momentum squared to the target nucleus, Q^{2}, is reconstructed based on the kinematics of the leading proton, and differential cross sections versus Q^{2} and the cross-section ratios of iron, lead, and carbon to scintillator are measured for the first time in a single experiment. The measurements show a dependence on the atomic number. While the quasielasticlike scattering on carbon is compatible with predictions, the trends exhibited by scattering on iron and lead favor a prediction with intranuclear rescattering of hadrons accounted for by a conventional particle cascade treatment. These measurements help discriminate between different models of both initial state nucleons and final state interactions used in the neutrino oscillation experiments.
The aim of this paper is to develop and validate an HPLC method to investigate the tissue distribution of gemifloxacin (GEM) in rats following intravenous administration and compare the penetration ...of this drug in different tissues undergoing normobaric and hyperbaric oxygen (HBO) exposure. The chromatographic conditions consisted of a C
18
column and mobile phase composition of triethylamine (0.5% v/v, pH 3.0), methanol and acetonitrile (65:28:7, v/v/v) at a flow rate of 1.0 mL min
−1
. The calibration curves were linear from 0.2 to 30 μg mL
−1
for GEM, with correlation coefficient
r
≥ 0.99. Retention times of GEM and furosemide (internal standard) were approximately 8 and 16 min, respectively. The intra-day variation was less than 5.56, 8.94 and 5.74% for lung, kidney and liver, respectively, and the inter-day variation was less than 1.58, 3.71 and 3.45% for lung, kidney and liver, respectively. The accuracy ranged from 89.0 to 112.9%. Recoveries of GEM and furosemide were up to 90%. Short-term, freeze–thaw, long-term and autosampler stability were demonstrated. The present study showed that the highest tissue concentration of GEM under normobaric exposure was obtained in the kidney (51.22 μg g
−1
), followed by liver (32.78 μg g
−1
) and lung (28.49 μg g
−1
). The
t
1/2
β obtained was 6.35, 2.83 and 2.41 h for lung, kidney and liver, respectively. Statistical difference (
p
< 0.05) was observed in rat tissues—lung, liver and kidney, when the rats were exposed to normobaric and HBO (2.5 h at 1.7 ATA).
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