Common noncommunicable diabetes mellitus disease has many complications in several parts of the human body. The oral cavity is one of the areas affected by diabetes mellitus conditions. The most ...common complications of diabetes mellitus in oral areas include increased drying of the mouth and increased oral diseases resulting from either microbial activity, such as dental caries, periodontal diseases, and oral candidiasis, or physiological problems, such as oral cancer, burning mouth syndrome, and temporomandibular disorders. Diabetes mellitus also has an impact on the diversity and quantity of oral microbiota. Oral infections promoted by diabetes mellitus mainly result from disturbance of the balance between different species of oral microbiota. Some oral species may be positively or negatively correlated with diabetes mellitus, while others may not be affected at all. The most numerous species in the presence of diabetes mellitus are those of phylum Firmicutes of bacteria such as hemolytic Streptococci, Staphylococcus spp., Prevotella spp., Leptotrichia spp., and Veillonella and species of the fungus Candida. Proteobacteria spp. and Bifidobacteria spp. are common microbiota that are negatively impacted by diabetes mellitus. In general, the effect of diabetes mellitus could include all types of oral microbiota, whether it is bacteria or fungi. The 3 types of association between diabetes mellitus and oral microbiota that will be illustrated in this review are increase, decrease, or lack of impact. As final inclusion, a great number of oral microbiota have increased in the presence of diabetes mellitus.
Rapid plasma-induced non-equilibrium electrochemistry (PiNE) at atmospheric pressure was used to prepare surfactant-free gold nanoparticles and copper oxide quantum dots. A suite of chemical and ...physical characterisation is carried out to assess the as-prepared materials. Nanofluids comprised of these nanoparticles in ethylene glycol have been prepared. The energy absorptive properties of the prepared nanofluids were investigated as a potential additive to the traditional working fluids used in solar thermal collectors. The application feasibility has been assessed by calculating a value of power which could be transferred to the thermal fluid. This work demonstrates an alternative and rapid method to produce nanofluids for solar thermal conversion.
Foam Sclerotherapy in Pelvic Congestion Syndrome Shahat, Mohammed; Hussein, Reda S.; Ahmed, Ahmed Khairy Sayed
Vascular and endovascular surgery,
07/2023, Letnik:
57, Številka:
5
Journal Article
Recenzirano
Chronic pelvic pain (CPP) is a prevalent condition in middle-aged women that represents a heavy social impact on the quality of life of those females. Treatment of pelvic congestion syndrome is a ...complex and controversial issue, but treatment can be one of 3 lines: medical therapy, endovascular treatment, and surgical intervention. The endovascular line was first introduced in 1993 and has been popular over other lines of treatment methods. This retrospective study was conducted in a tertiary university hospital over 24 months, from March 2019 to March 2021. Forty patients with PGS were managed by left ovarian vein TCFS. The Institutional Review Board waived the need for ethics approval or informed consent to use anonymized and retrospectively analyzed data. The mean age of enrolled women was 33.80 ± 6.54 years, ranging between 20 and 45 years. Trans-catheter ethanolamine foam embolization is an effective and safe method to treat pelvic and atypical lower limb varices.
Early detection of brain tumors can save precious human life. This work presents a fully automated design to classify brain tumors. The proposed scheme employs optimal deep learning features for the ...classification of FLAIR, T1, T2, and T1CE tumors. Initially, we normalized the dataset to pass them to the ResNet101 pretrained model to perform transfer learning for our dataset. This approach results in fine-tuning the ResNet101 model for brain tumor classification. The problem with this approach is the generation of redundant features. These redundant features degrade accuracy and cause computational overhead. To tackle this problem, we find optimal features by utilizing differential evaluation and particle swarm optimization algorithms. The obtained optimal feature vectors are then serially fused to get a single-fused feature vector. PCA is applied to this fused vector to get the final optimized feature vector. This optimized feature vector is fed as input to various classifiers to classify tumors. Performance is analyzed at various stages. Performance results show that the proposed technique achieved a speedup of 25.5x in prediction time on the medium neural network with an accuracy of 94.4%. These results show significant improvement over the state-of-the-art techniques in terms of computational overhead by maintaining approximately the same accuracy.
Digital image correlation (DIC) is an optical technique used to measure surface displacements and strains in materials and structures. This technique has demonstrated significant utility in ...structural examination and monitoring. This manuscript offers a comprehensive review of the contemporary research and applications that have leveraged the DIC technique in laboratory-based structural tests. The reviewed works encompass a broad spectrum of structural components, such as concrete beams, columns, pillars, masonry walls, infills, composite materials, structural joints, steel beams, slabs, and other structural elements. These investigations have underscored the efficacy of DIC as a metrological instrument for the precise quantification of surface deformation and strain in these structural components. Moreover, the constraints of the DIC technique have been highlighted, especially in scenarios involving extensive or complex test configurations. Notwithstanding these constraints, the effectiveness of the DIC methodology has been validated as a strain measurement instrument, offering numerous benefits such as non-invasive operation, full-field measurement capability, high precision, real-time surveillance, and compatibility with integration into other measurement instruments and methodologies.
We explored the factors and mechanisms of the adsorption and photocatalytic activity of iron oxide nanoparticles (Fe
2
O
3
NPs) coated with poly(sodium 4-styrenesulfonate) sodium salt (PSS), and ...poly(allylamine hydrochloride) (PAH) polyelectrolytes using the layer-by-layer technique. We synthesized Fe
2
O
3
NPs using the precipitation method at two calcination temperatures, 200 ℃ and 500 ℃. We studied the activity of bare and surface modified Fe
2
O
3
NPs toward fluorescein sodium salt (FSS) dye upon illumination with UV light compared with that under dark conditions to assess the effect of the oxidative stress because of the reactive oxygen species (ROS). The bare and surface modified Fe
2
O
3
NPs display excellent adsorption and photocatalytic activity for FSS dye. The Langmuir isotherm and the pseudo-second order kinetic model fit well with the adsorption properties of the Fe
2
O
3
NPs. The nanoparticles of the anionic surface (Fe
2
O
3
NPs/PSS) showed much lower adsorption and photocatalytic activity than the ones with a cationic surface functionality (Fe
2
O
3
NPs/PSS/PAH and bare Fe
2
O
3
NPs). The impact of the Fe
2
O
3
NPs surface coating was discovered to be much stronger than the ROS impact because of irradiation with UV light. This indicates that the nanoparticles attachment to the FSS dye is much more important for their adsorption and photocatalytic action than the ROS generation alone. This could be explained by the poor adhesion of Fe
2
O
3
NPs/PSS to the FSS dye due to electrostatic repulsion. In contrast, the particle-FSS dye electrostatic adhesion in the case of cationic Fe
2
O
3
NPs/PSS/PAH and bare Fe
2
O
3
NPs led to enhanced adsorption and photocatalytic action. Additionally, it was discovered that the Fe
2
O
3
NPs/PSS/PAH and bare Fe
2
O
3
NPs were extremely selective for anionic FSS over cationic crystal violet (CV) dye, making it simple to separate the two dyes from aqueous solutions of dye mixtures. The data also displays that bare and surface modified Fe
2
O
3
NPs have good recyclability, showing that they would be an economical material with significant potential in water treatment.
Graphical abstract
The capacity of fully grown oocytes to regulate their own microenvironment by paracrine factors secreted by the oocyte (oocyte-secreted factors, OSFs) may in turn contribute to oocyte developmental ...competence. Here, we investigated if OSFs have a direct influence on oocyte developmental competence during in vitro maturation (IVM). Bovine cumulus–oocyte complexes (COCs) were aspirated from abattoir-derived ovaries and matured in serum-free medium. COCs were either co-cultured with denuded oocytes (DOs) or treated with specific OSFs: recombinant bone morphogenetic protein 15 (BMP15) and/or growth differentiation factor 9 (GDF9). Following maturation, embryos were fertilized and cultured in vitro and blastocyst development and cell number were assessed on day 8. Co-culturing intact COCs with DOs did not affect cleavage rate, but increased (
P
<
0.001) the proportion of cleaved embryos that reached the blastocyst stage post-insemination from 39% to 51%. OSFs also altered blastocyst cell allocation as co-culture of COCs with DOs significantly increased total and trophectoderm cell numbers, compared to control COCs. BMP15 alone, GDF9 alone or the two combined all (
P
<
0.05) increased the proportion of oocytes that reached the blastocyst stage post-insemination from 41% (controls) to 58%, 50% and 55%, respectively. These results were further verified in neutralization experiments of the exogenous growth factors and of the native OSFs. Follistatin and the kinase inhibitor SB-431542, which antagonize BMP15 and GDF9, respectively, neutralized the stimulatory effects of the exogenous growth factors and impaired the developmental competence of control COCs. These results demonstrate that OSFs, and particularly BMP15 and GDF9, enhance oocyte developmental competence and provide evidence that OSF regulation of the COC microenvironment is an important determinant of oocyte developmental programming.
The automatic creation of 3D animation from natural language text is used in many fields. The main target of this paper is to produce a 3D cartoon from a text input. Therefore, we need to analyze the ...input corpus to extract useful information by employing theories and tools from linguistics and natural language processing in addition to computer graphics for human language visualization. The system operates through two phases. The NLP phase, in which input text passes first through a coreference resolution solver in order to remove pronouns and substitute them with their corresponding nouns followed by a dependency parser in order to detect subject-action-object (SAO) relations in the resolved text. The sequence of SAOs resulting from the NLP phase is passed to the graphics phase. In the graphics phase a 3D animated video cartoon is generated by visualizing each SAO extracted in the NLP phase and Storytelling using the Unity game engine platform. The main contribution of this work is that the input does not have to be a screenplay. It is also demonstrated that performing coreference resolution before dependency parsing resulted in a more compact sequence of SAOs.
Purpose To study the tomographic and pathomorphologic features of dome-shaped maculas with swept-source optical coherence tomography (OCT). Design Prospective, cross-sectional study. Methods The ...macular area of 51 highly myopic eyes (35 patients) with dome-shaped maculas was studied with swept-source OCT at 1050 nm. Three-dimensional (3-D) data sets were obtained with raster scanning covering a 12 × 8-mm2 area; 3-D images of the posterior pole were constructed by autosegmentation of the retinal pigment epithelium (RPE). Results In all reconstructed 3-D images of the RPE, 2 outward concavities were seen within the posterior staphyloma and a horizontal ridge was formed between these 2 concavities. In 42 of these eyes, this horizontal ridge was band shaped. The vertical OCT section through the fovea showed a convex configuration of RPE, but the horizontal section showed an almost flat RPE line. In 9 eyes, 3-D images showed a typical dome-shaped convexity within the staphyloma. OCT scans showed no outward protrusions in the external scleral surface, but marked scleral thinning was seen consistent with the 2 outward concavities of the RPE. The sclera of the fovea (518.6 ± 97.6 μm) was significantly thicker than that in all 4 quadrants of the parafoveal area (range, 277.2 to 360.3 μm; P < .001). Conclusions In highly myopic eyes with a dome-shaped macula, a horizontal ridge is formed within the posterior staphyloma by uneven thinning of the sclera.
Schiff bases may be a core to synthesize different new chemical ligands. They also have many biological activities by its azomethine group. Antimicrobial activities of new synthetic oxime derivatives ...against bacteria and fungi were investigated.
o
-Aminoacetophenoneoxime (
o
-AAOX) and
m
- Aminoacetophenoneoxime (
m
-AAOX) were used as precursors in the synthesis of five oxime derived ligands (L1-5). Two tridentates (L1 and L4) were derived from
o
-AAOX and three bidentates (L2, L3, and L5) were derived from
m
-AAOX. The structure of prepared ligands was confirmed using FT-IR, NMR (
1
H and
13
C), and UV-Visible spectral analysis as well as melting point and element analysis. Antimicrobial activities of five ligands were determined by the disk diffusion method. Only the
m
-AAOX ligands showed an antimicrobial action. The L2 was the most effective ligand on the tested microorganisms, especially against
Staphylococcus aureus
(MIC, 8 mg/ml) and
Candida glabrata
(MIC, 5.5 mg/ml). The L5 ligand showed only antifungal effect.
Kocuria rosea
was resistant to all ligands, while
Candida albicans
was susceptible to most of them. In conclusion; the
m
-AAOX derivatives are an active compound against bacteria and fungi than the
o
-AAOX derivatives. The ligand L2 has more inhibitory effects on bacteria, while fungi were inhibited by other
m
-AAOX derivatives. The new Schiff bases of the
m
-AAOX derivatives may be regarded as promising antimicrobial agents.
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