THIS PAPER WILL DESCRIBE a single chip CMOS 32b micro-processor supporting a smart memory hierarchy with on chip Cache and TLB (Transmission Lookaside Buffer(.
The study group was organized to evaluate the usefulness of cefmenoxime (CMX) injection, a new synthetic cephalosporin, for the treatment of infections in the field of obstetrics and gynecology. ...Fundamental and clinical studies were made by the society and the following results were obtained. 1. The peak distribution of CMX's MIC for E. coli, Klebsiella sp., Enterobacter sp., Bacteroides sp. and Peptococcus sp. isolated from obstetrical and gynecological infections with relatively high frequencies area 0.1, less than or equal to 0.05, 0.2, 3.13, 1.56 micrograms/ml, respectively, with an inoculation of 10(6) cells/ml. 2. When 1 g of CMX is administered by intravenous drip infusion for 1 hour, the maximum concentrations in various tissues of female genital organs were as follows: 14.2 and 13.2 micrograms/g in ovary and oviduct, respectively, at 1.20 hours after the start of administration, and 16.9 and 26.3 micrograms/g in corpus uteri and cervix uteri, respectively, after 1 hour. As for the transfer to the exudate in the pelvic dead cavity, the peak concentration was 15.6 micrograms/ml after 2.13 hours. 3. In the clinical studies, CMX was given to 258 cases with female genital organ infections and others. As for the clinical effects, with exclusion of 3 cases in which other antibiotics are concomitantly used, responses were excellent in 76 cases, good in 162 cases and poor in 17 cases, among 255 cases in total. The efficacy rate was 93.3%. The efficacy rates by diseases were 97.1% (68/70) for intrauterine infections, 88.8% (79/89) for intrapelvic infections, 98.4% (62/63) for adnexitis, and 100% (23/23) for infections of external genital organs. As for the clinical effects on causative bacteria, the efficacy rates were 100% (19/19) for single infections due to Gram-positive bacteria, 94.8% (55/58) for single infections due to Gram-negative bacteria, and 88.2% (15/17) for single infections due to anaerobic bacteria. And its efficacy rates were 89.6% (69/77) for mixed infection cases. Side effects were observed in 2 cases (0.8%); 1 case with eruption, and 1 case with diarrhea and vomiting. As for abnormal laboratory findings, lower white blood cell count was observed in 2 cases and elevation of the values regarding hepatic functions in 9 cases. All cases were returned to the normal after the completion of the administration. Cefmenoxime showed a satisfactory clinical efficacy and a potent bacteriological effect in treatment of the infections in the field of obstetrics and gynecology, and it has been concluded that cefmenoxime will be useful addition to the antibiotics for the therapy of these infections.
The increasing number of breast cancer patients in Japan necessitates the development of a useful screening method. Previous studies using a laser transmission photo-scanner for breast lesions showed ...its use to be feasible in screening for small lesions in small breasts. An increase in the power of the laser beam, however, is necessary to detect small tumors in larger breasts or large tumors. In cases where mammography was compared with laser transmission images, the latter were compatible with published data. More precise examination of laser transmission photo-scanning with the addition of spectro-analysis is the next step.
As a part of world-wide survey as: o the distribution of streptococcus pyogenes, present studies were carried out in our country by agglutination method. Kanagawa Prefectural Public Health Laboratory ...was requested, as an only institute in Asia, to participate in this international survey which was arranged. by Dr. Williams in Streptococcus & Staphylococcus Reference Laboratory in London. For this persecution a domestic study team was also arranged by us under the financial aid of Scientific Research Fund_ of Ministry of Health and Welfare. During the survey period from June 1964 to May 1965, 336 strains of streptococcus pyogenes from the same number of confirmed cases of streptococcal diseases (one strain from one patient) were collected from eleven collecting laboratories which located north from Hokkaido down through Tohoku- and. Kanto district to Kansai-, Chugoku- and Shikoku districts. Out of 21 types 11 were actually detected within this country. They were: T4 (48.8%), T6 (15.7%), T25, T1 (2.9%), T22 (2.7%), T3, T5, T9, T14, T23, 5/27/44 and Untypable (20.5%). The absolute predominancy of the type 4 was apparent. However, the comparison each of the: semianual data extending over one year from 1964 to 1965 revealed that in the latter half period thepercentage of type 6 remarkably gained, catching up with the level of type 4 which was absolutely predominant in the preceded period. This suggests a possibility that the alteration of the dominant type causing: a major or epidemic may actually occur within a relatively short period of time (within a year) and between limited kinds of commoner types. Present survey showed that the agglutination-typing would be a method of so expedience as well as of worth as to allow laboratories in hospitals or health centres to adopt it, provided that a route for supplying typing-sera will be set up.
