Two-phase flows in large diameter channels have a great deal of importance in a wide variety of industrial applications. Nuclear systems, petroleum refineries, and chemical processes make extensive ...use of larger systems. Flows in such channels have very different properties from flows in smaller channels which are typically used in experimental research. In this paper, the various differences between flows in large and small channels are highlighted using the results of previous experimental and analytical research. This review is followed by a review of recent experiments in and model development for flows in large diameter channels performed by the authors. The topics of these research efforts range from void fraction and interfacial area concentration measurement to flow regime identification and modeling, drift-flux modeling for high void fraction conditions, and evaluation of interfacial area transport models for large diameter channels.
► Grid spacers have a significant but not well understood effect on flow behavior and development. ► Two different length scales are present in rod bundles, which must be accounted for in modeling. ► ...An easy-to-implement empirical model has been developed for the two-phase friction multiplier.
The behavior of reactor systems is predicted using advanced computational codes in order to determine the safety characteristics of the system during various accidents and to determine the performance characteristics of the reactor. These codes generally utilize the two-fluid model for predictions of two-phase flows, as this model is the most accurate and detailed model which is currently practical for predicting large-scale systems. One of the weaknesses of this approach however is the need to develop constitutive models for various quantities. Of specific interest are the models used in the prediction of void fraction and pressure drop across the rod bundle due to their importance in new Natural Circulation Boiling Water Reactor (NCBWR) designs, where these quantities determine the coolant flow rate through the core. To verify the performance of these models and expand the existing experimental database, data has been collected in an 8×8 rod bundle which is carefully scaled from actual BWR geometry and includes grid spacers to maintain rod spacing. While these spacer grids are ’generic’, their inclusion does provide valuable data for analysis of the effect of grid spacers on the flow. In addition to pressure drop measurements the area-averaged void fraction has been measured by impedance void meters and local conductivity probes have been used to measure the local void fraction and interfacial area concentration in the bundle subchannels. Experimental conditions covered a wide range of flow rates and void fractions up to 80%.
In the two-fluid model, it is important to give an accurate prediction for the interfacial area concentration. In order to achieve this goal, the interfacial area transport equation has been ...developed. This study focuses on the benchmark of IATE performance in a rod bundle geometry. A set of interfacial area concentration source and sink term models are proposed for a rod bundle geometry based on the confined channel IATE model. This model was selected as a basis because of the relative similarity of the two geometries. Benchmarking of the new model with interfacial area concentration data in an 8×8 rod bundle test section which has been scaled from an actual BWR fuel bundle is performed. The model shows good agreement in bubbly and cap-bubbly flows, which are similar in many types of geometries, while it shows some discrepancy in churn-turbulent flow regime. This discrepancy may be due to the geometrical differences between the actual rod bundle test facility and the facility used to collect the data which benchmarked the original source and sink models.
Air-sea CO2 fluxes over the Pacific Ocean are known to be characterized by coherent large-scale structures that reflect not only ocean subduction and upwelling patterns, but also the combined effects ...of wind-driven gas exchange and biology. On the largest scales, a large net CO2 influx into the extratropics is associated with a robust seasonal cycle, and a large net CO2 efflux from the tropics is associated with substantial interannual variability. In this work, we have synthesized estimates of the net air-sea CO2 flux from a variety of products, drawing upon a variety of approaches in three sub-basins of the Pacific Ocean, i.e., the North Pacific extratropics (18-66° N), the tropical Pacific (18° S-18° N), and the South Pacific extratropics (44.5-18° S). These approaches include those based on the measurements of CO2 partial pressure in surface seawater (pCO2 sw), inversions of ocean-interior CO2 data, forward ocean biogeochemistry models embedded in the ocean general circulation models (OBGCMs), a model with assimilation of pCO2 sw data, and inversions of atmospheric CO2 measurements. Long-term means, interannual variations and mean seasonal variations of the regionally integrated fluxes were compared in each of the sub-basins over the last two decades, spanning the period from 1990 through 2009. A simple average of the long-term mean fluxes obtained with surface water pCO2 diagnostics and those obtained with ocean-interior CO2 inversions are -0.47 ± 0.13 Pg C yr-1 in the North Pacific extratropics, +0.44 ± 0.14 Pg C yr-1 in the tropical Pacific, and -0.37 ± 0.08 Pg C yr-1 in the South Pacific extratropics, where positive fluxes are into the atmosphere. This suggests that approximately half of the CO2 taken up over the North and South Pacific extratropics is released back to the atmosphere from the tropical Pacific. These estimates of the regional fluxes are also supported by the estimates from OBGCMs after adding the riverine CO2 flux, i.e., -0.49 ± 0.02 Pg C yr-1 in the North Pacific extratropics, +0.41 ± 0.05 Pg C yr-1 in the tropical Pacific, and -0.39 ± 0.11 Pg C yr-1 in the South Pacific extratropics. The estimates from the atmospheric CO2 inversions show large variations amongst different inversion systems, but their median fluxes are consistent with the estimates from climatological pCO2 sw data and pCO2 sw diagnostics. In the South Pacific extratropics, where CO2 variations in the surface and ocean interior are severely undersampled, the difference in the air-sea CO2 flux estimates between the diagnostic models and ocean-interior CO2 inversions is larger (0.18 Pg C yr-1 ). The range of estimates from forward OBGCMs is also large (-0.19 to -0.72 Pg C yr-1 ). Regarding interannual variability of air-sea CO2 fluxes, positive and negative anomalies are evident in the tropical Pacific during the cold and warm events of the El Niño-Southern Oscillation in the estimates from pCO2 sw diagnostic models and from OBGCMs. They are consistent in phase with the Southern Oscillation Index, but the peak-to-peak amplitudes tend to be higher in OBGCMs (0.40 ± 0.09 Pg C yr-1 ) than in the diagnostic models (0.27 ± 0.07 Pg C yr-1 ).
In view of the practical importance of the drift-flux model for two-phase flow analysis in general and in the analysis of nuclear-reactor transients and accidents in particular, the distribution ...parameter and the drift velocity have been studied for bubbly flow regime. The constitutive equation that specifies the distribution parameter in the bubbly flow has been derived by taking into account the effect of the bubble size on the phase distribution, since the bubble size would govern the distribution of the void fraction. A comparison of the newly developed model with various fully developed bubbly flow data over a wide range of flow parameters shows a satisfactory agreement. The constitutive equation for the drift velocity developed by Ishii has been reevaluated by the drift velocity calculated by local flow parameters such as void fraction, gas velocity and liquid velocity measured under steady fully developed bubbly flow conditions. It has been confirmed that the newly developed model of the distribution parameter and the drift velocity correlation developed by Ishii can also be applicable to developing bubbly flows.
The oceanic uptake and resulting storage of the anthropogenic CO2 (Cant) that humans have emitted into the atmosphere moderates climate change. Yet our knowledge about how this uptake and storage has ...progressed in time remained limited. Here, we determine decadal trends in the storage of Cant by applying the eMLR(C*) regression method to ocean interior observations collected repeatedly since the 1990s. We find that the global ocean storage of Cant grew from 1994 to 2004 by 29 ± 3 Pg C dec−1 and from 2004 to 2014 by 27 ± 3 Pg C dec−1 (±1σ). The storage change in the second decade is about 15 ± 11% lower than one would expect from the first decade and assuming proportional increase with atmospheric CO2. We attribute this reduction in sensitivity to a decrease of the ocean buffer capacity and changes in ocean circulation. In the Atlantic Ocean, the maximum storage rate shifted from the Northern to the Southern Hemisphere, plausibly caused by a weaker formation rate of North Atlantic Deep Waters and an intensified ventilation of mode and intermediate waters in the Southern Hemisphere. Our estimates of the Cant accumulation differ from cumulative net air‐sea flux estimates by several Pg C dec−1, suggesting a substantial and variable, but uncertain net loss of natural carbon from the ocean. Our findings indicate a considerable vulnerability of the ocean carbon sink to climate variability and change.
Plain Language Summary
The ocean takes up about 30% of the anthropogenic CO2 that is emitted to the atmosphere by human activities. The removal of this anthropogenic CO2 from the atmosphere counteracts climate change. The rate at which the ocean takes up anthropogenic CO2 is controlled by its transport from the surface to the depth of the ocean, where most of it accumulates. Thus, we can quantify and understand the oceanic uptake by keeping track of the accumulation of anthropogenic CO2 in the ocean interior. In this study, we use a global collection of measurements of CO2 in seawater to infer the temporal evolution of this accumulation between 1994 and 2014. We find that the ocean continued to act as a strong sink for CO2 over this period, removing, on average, nearly 30 billion tons of carbon per decade. However, we also detect a possible weakening of this uptake, since the accumulation of anthropogenic CO2 during the second decade was not as large as expected from the increase in atmospheric CO2. Our findings suggest that the ocean sink for CO2 might further shrink as climate change progresses.
Key Points
The global ocean storage of anthropogenic carbon grew by 29 ± 3 and 27 ± 3 Pg C dec−1 from 1994 to 2004 and 2004 to 2014, respectively
The change in oceanic storage of anthropogenic carbon relative to the atmospheric CO2 growth decreased by 15 ± 11% from the first to the second decade
This reduction is attributed to a decrease of the ocean buffer capacity and changes in ocean circulation
Controversy exists as to whether the threshold for blood pressure-lowering treatment should differ between people with and without type 2 diabetes. We aimed to investigate the effects of blood ...pressure-lowering treatment on the risk of major cardiovascular events by type 2 diabetes status, as well as by baseline levels of systolic blood pressure.
We conducted a one-stage individual participant-level data meta-analysis of major randomised controlled trials using the Blood Pressure Lowering Treatment Trialists' Collaboration dataset. Trials with information on type 2 diabetes status at baseline were eligible if they compared blood pressure-lowering medications versus placebo or other classes of blood pressure-lowering medications, or an intensive versus a standard blood pressure-lowering strategy, and reported at least 1000 persons-years of follow-up in each group. Trials exclusively on participants with heart failure or with short-term therapies and acute myocardial infarction or other acute settings were excluded. We expressed treatment effect per 5 mm Hg reduction in systolic blood pressure on the risk of developing a major cardiovascular event as the primary outcome, defined as the first occurrence of fatal or non-fatal stroke or cerebrovascular disease, fatal or non-fatal ischaemic heart disease, or heart failure causing death or requiring hospitalisation. Cox proportional hazard models, stratified by trial, were used to estimate hazard ratios (HRs) separately by type 2 diabetes status at baseline, with further stratification by baseline categories of systolic blood pressure (in 10 mm Hg increments from <120 mm Hg to ≥170 mm Hg). To estimate absolute risk reductions, we used a Poisson regression model over the follow-up duration. The effect of each of the five major blood pressure-lowering drug classes, including angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, β blockers, calcium channel blockers, and thiazide diuretics, was estimated using a network meta-analysis framework. This study is registered with PROSPERO, CRD42018099283.
We included data from 51 randomised clinical trials published between 1981 and 2014 involving 358 533 participants (58% men), among whom 103 325 (29%) had known type 2 diabetes at baseline. The baseline mean systolic/diastolic blood pressure of those with and without type 2 diabetes was 149/84 mm Hg (SD 19/11) and 153/88 mm Hg (SD 21/12), respectively. Over 4·2 years median follow-up (IQR 3·0–5·0), a 5 mm Hg reduction in systolic blood pressure decreased the risk of major cardiovascular events in both groups, but with a weaker relative treatment effect in participants with type 2 diabetes (HR 0·94 95% CI 0·91–0·98) compared with those without type 2 diabetes (0·89 0·87–0·92; pinteraction=0·0013). However, absolute risk reductions did not differ substantially between people with and without type 2 diabetes because of the higher absolute cardiovascular risk among participants with type 2 diabetes. We found no reliable evidence for heterogeneity of treatment effects by baseline systolic blood pressure in either group. In keeping with the primary findings, analysis using stratified network meta-analysis showed no evidence that relative treatment effects differed substantially between participants with type 2 diabetes and those without for any of the drug classes investigated.
Although the relative beneficial effects of blood pressure reduction on major cardiovascular events were weaker in participants with type 2 diabetes than in those without, absolute effects were similar. The difference in relative risk reduction was not related to the baseline blood pressure or allocation to different drug classes. Therefore, the adoption of differential blood pressure thresholds, intensities of blood pressure lowering, or drug classes used in people with and without type 2 diabetes is not warranted.
British Heart Foundation, UK National Institute for Health Research, and Oxford Martin School.
Microfibrillar reinforced composites (MFC) based on blends from recycled poly(ethyleneterephthalate) (PET), polypropylene (PP) and a compatibilizer (ethylene-glycidyl methacrylate (E-GMA)) were ...prepared under industry-relevant conditions by melt extrusion, followed by continuous cold drawing. The PET/PP/E-GMA weight rations amounted to 40/60/0, 40/59/1, 40/57/3, 40/54/6 and 40/51/9, respectively. Test specimens were prepared by compression- and injection molding (CM and IM) at processing temperatures either below or above the melting temperatures of PET. Samples of each stage of MFC manufacturing and processing were characterized by means of scanning electron microscopy (SEM), wide-angle X-ray scattering (WAXS), and mechanical testing. SEM and WAXS showed that the extruded blends are isotropic, but become highly oriented after drawing, and they are converted into MFC structured polymer–polymer composites during CM and IM. The MFC structures are characterized by an isotropic PP matrix, which contains reinforcing PET fibrils of different orientations after IM or of uniaxial orientation in the case of CM. The flexural modulus and the flexural strength of the IM samples are by 50% better than those of the neat PP, without expressing any clear effect of the amount of E-GMA in the blend. This was different from the CM samples, in which both the flexural modulus and the flexural strength increased with an increase of E-GMA part.