To evaluate the auditory functions and progress of speech development in children with and without cochlear anomalies who underwent cochlear implantation due to prelingual profound sensorineural ...hearing loss (SNHL).
This study was conducted at Gaziantep University Faculty of Medicine Ear-Nose-Throat Department, between October 2006 and December 2007. A total of 69 children (aged 6 to 24 months) diagnosed with profound SNHL were included. Patients were divided into two groups with respect to the presence of inner ear anomalies: Group-1 consisted of 41 children without inner ear anomaly, whereas Group-2 was composed of 28 patients with inner ear anomalies. The auditory performance was assessed using Listening Progress Profile Test (LPPT) and Monosyllabic Trochee Polysyllabic Test (MTP), the subsections of Evaluation of Auditory Responses to Speech (EARS) test battery.
Preoperative LPPT scores were 5 (12%) in both groups. Mean LPPT values after fitting in Group-1 and Group-2 on 1
, 3
and 6
months were 18.5 (44.1%) and 19 (45.6%); 27 (64.2%) and 28 (67.3%); 31 (75%) and 34 (83%), respectively. Postoperatively, MTP scores in Group-1 and Group-2 were 7.5 (62%) and 7.7 (64%) for 3-words set; 10.4 (58%) and 10.6 (59%) for 6-words set; 14.3 (60%) and 14 (59%) for 12-words set, respectively. The rate of stimulation for electrodes was 1345 q/u (quick/unit) in Group-1 and 1310 q/u in Group-2. No statistically significant difference was detected between groups for variables under investigation.
Cochlear implantation is an effective treatment in children with prelingual profound SNHL. Auditory performance and advancement of speech are similar for children with and without inner ear anomalies.
In this study the authors evaluated the outcomes of tracheal resection and anastomosis in postintubation tracheal stenosis. The authors also aimed to identify clinical and radiological factors ...associated with restenosis. Thirty-four consecutive patients were included in the study. Patients with subglottic stenosis who underwent procedures involving cricoid cartilage and patients with other etiologies were excluded from the study. Univariate analysis was performed to determine the risk factors for restenosis. Receiver operating characteristic (ROC) curves were generated for the diameter of the narrowest part of the trachea (Dst) and the distance between cricoid cartilage and stenosis (Dcs). Of the 34 patients, 31 (91.1%) patients were successfully decannulated. Nineteen (55.8%) patients had complications. After univariate analysis, Dst (P = 0.001), Dcs (P = 0.001), smoking (P = 0.007) and grade of the stenosis (P = 0.003) were significantly associated with restenosis. The sensitivity and specificity were 90.9% and 77.3%, respectively, when the cutoff value for Dst was 4 mm. Sensitivity and specificity were 72.7% and 100%, respectively, when the cutoff value for Dcs was 10 mm. Tracheal resection and anastomosis is an effective surgical method for treating postintubation tracheal stenosis. In our series, 91.1% of the patients with postintubation tracheal stenosis were successfully decannulated. Restenosis was the most common complication. The diameter of the narrowest part of the trachea (Dst), the distance between cricoid cartilage and stenosis (Dcs), smoking and grade of stenosis were significantly associated with restenosis.
BACKGROUND/AIMS In this study, it was aimed to evaluate systemic inflammatory markers as prognostic factors in patients with parotid gland tumors. MATERIAL and METHODS Between 20l4and20l9, ...retrospective analysis of 181 patients who applied to Otorhinolaryngology Clinic and operated due to parotid gland tumor was performed. Additionally, 63 patients without tumor were included in the study as a control group. According to the post-operative histopathological diagnosis, it was divided into two groups as patients with benign and malignant tumors. The patients' age, gender, pre-operative blood tests, neutrophil-lymphocyte ratio(NLR), platelet-lymphocyte ratio(PLR), MPV-platelet ratio(MPVPR), MPV-lymphocyte ratio(MPVLR) and Systemic inflammatory index(SII) parameters calculated. RESULTS RBC, hemoglobin, hematocrit and lymphocyte levels were statistically significantly lower in patients with malign tumor compared to other groups. In addition, compared to benign tumor group, NLR, PLR and Sll levels significantly increased and MPVLR level significantly decreased in patients with malign tumor. Consequently, according to ROC analysis for malign tumor, RDW, lymphocyte, NLR, PLR, MPVLR and Sll were significant prognostic factors (P = .036, P = .002, P= .033, P= .004, P= .001, P= .049, respectively). CONCLUSION RDW, lymphocyte, NLR, PLR, MPVLR and Sll parameters, which are fast, cheap and easy to use, can be used in the differential diagnosis of benign and malignant masses in patients with parotid gland tumors. Keywords: Parotid gland tumors, red cell distribution width, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, systemic inflammatory index
Abstract We present a case of synchronous bilateral carotid body tumor and vagal paraganglioma in a 49-year-old man who presented with 3 months history of tenderness and palpable neck masses ...bilaterally. An encapsulated mass which was thought to be a carotid body tumor and an incidental 3 cm × 2 cm, 5 cm × 1 cm, 5 cm mass which seemed to be originated from vagus nerve were dissected from the left side. Pathology revealed carotid body tumor and vagal paraganglioma. Six months after the first operation, the carotid body tumor on the right side was totally excised. A discussion of this case is followed by a review of the literature surrounding this rare clinic and pathological entity.
Objective: Human papillomavirus infections may have a role in the development of oral cavity and oropharynx carcinomas. Human papil lomav irus- positive oral cavity and oropharyngeal carcinomas ...differ from human papil lomav irus- negat ive in that to occur in younger, are more frequent in men, and are strongly associated with sexual behavior. These observations lead to the treatment options and outcomes in human papil lomav irus- relat ed tumors, and the questions of targeted treatment that can be performed in the coming years have come to age. Methods: This prospective study was conducted at Gaziantep University, medical faculty, otorhinolaryngology department. Patients with squamous cell carcinomas of non-lip oral cavity and oropharyngeal admitted to our department were included in the study. Samples from the cases were immun ohist ochemically stained. Sections were examined by light microscopy. Results: The 55 cases P16 (76.4%) expressions were detected to be positive, and 17 (23.6%) cases were negative. There was no statistically significant correlation between prognostic parameters and p16 expressions. However, a significant difference was detected between human papil lomav irus- positive and negative groups in regard to survival in oropharyngeal carcinoma. Conclusion: Disease management can consider human papil lomav irus- positive oral cavity and oropharyngeal carcinomas as a separate group. human papil lomav irus- positive oral cavity and oropharyngeal carcinomas respond better to chemotherapy and radiotherapy than human papilloma virus-negative cancers. The presence/absence of human papillomavirus 16 might be considered a prognostic marker, but its reliability has not yet been confirmed. In future clinical studies, cancer centers should classify head--neck patients with respect to human papillomavirus status. However, we must always emphasize that the best treatment for cancer in which the main pathogenic agent is known is protection. Keywords: Oral cavity, oropharynx, neoplasms, human papillomavirus p16, immunohistochemistry
The objectives of this study were to investigate the typical clinical presentation, diagnosis and treatment of mycobacterial cervical lymphadenitis (MCL). Medical records of 87 patients who were ...treated for MCL were retrospectively reviewed. Definitive diagnosis of MCL was made when a neck mass persisted for several weeks or months and one or more of the following was obtained: (1) positive mycobacterial cultures from biopsy material; (2) Positive mycobacterial staining of biopsy material; (3) Granulomatous inflammation and caseating necrosis on histopathological examination of biopsy material. Clinical findings were reviewed prior to treatment. The treatment included standard antituberculous medications followed by surgery in which either total excision or selective nodal dissection of the cervical lump was made. Follow-up results are presented. The chief complaint was a cervical mass that was localized mostly to the posterior cervical or submandibular regions. A fistula formation was encountered in 11.5 per cent. All patients recovered from MCL by combined antituberculous drug and surgical treatments. Clinical presentation of the disease and histopathological assessment are important in the diagnosis of MCL as well as in the differential diagnosis of tuberculous and nontuberculous MCL. Utilizing the combined medical and surgical treatment options, both tuberculous and non-tuberculous cervical adenitis can be treated successfully.
Abstract Objectives The aim of this study was to evaluate patients who underwent endoscopic sphenoid sinus surgery for isolated sphenoid sinus disease. We also investigated the impact of sphenoid ...sinus surgery on headache intensity. Material and methods Twenty-one consecutive patients who underwent endoscopic sphenoidotomy for isolated sphenoid sinus disease were included in the study. Diagnosis of isolated sphenoid sinus pathology was based on history, physical examination, and radiologic evaluation. All patients had headache with various localizations. Pre- and postoperative headache intensity of patients was scored using a visual analogue scale (VAS). Results The most common location of headache was the vertex (24%). The preoperative and postoperative mean VAS scores for headache were 8.24 ± 0.94 and 2.67 ± 1.49, respectively. Statistical comparison revealed a significant improvement in headache intensity (p < 0.01). Polyps (33.3%) were the most common pathology, followed by inflammation (23.8%). Conclusions The most common presenting symptom of isolated sphenoid sinus disease is headache. In this study, we demonstrated that headache induced by isolated sphenoid disease can be relieved by endoscopic sphenoidotomy. Sphenoid sinus disease should be considered in the differential diagnosis of patients presenting with subacute or chronic headache.
Tinnitus is described as the perception of sound without any external acoustic stimulation. Any pathology of auditory pathways or any system of the human body may result with tinnitus. The ...pathophysiology of tinnitus accompanying the disorders of auditory system is not fully understood and there is not any particular effective treatment method has been specified. Tinnitus masking therapy has been reported as an effective treatment modality in the treatment of tinnitus. In this study, the results of tinnitus masking treatment on the parameters were evaluated prospectively.
Patients with normal physical examination was enrolled in the study. Blood tests (complete blood count, biochemical analysis of lipid profile, and thyroid hormones), pure tone audiometry, tympanometric measurement of the middle ear pressure and stapedial reflexes were performed, Sixty six patients with normal results of blood tests and normal hearing thresholds with type A tympanogram were included. Tinnitus sufferers questionnaires (socio-demographics, clinical information, Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI) was filled, audiological tests were performed, tinnitus parameters (frequency, intensity, minimal masking levels, residual inhibition) were measured. After four weeks of the treatment the questionnaires were repeated.
Masking treatment for tinnitus patients resulted with significant decrease in Tinnitus Handicap Inventory and VAS scores. After four weeks of the masking treatment the questionnaire was repeated. Twenty patients did not respond to treatment.
Masking therapy is one of the most effective methods of treatment for tinnitus patients. Masking therapy, that is not invasive and cost-effective has an important place in the treatment of tinnitus. Especially in a short time provides a significant reduction in tinnitus parameters.
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