Giant Abdominal Aortic Aneurysm in Bone Scan Çayır, Derya; Bozkurt, Mehmet; Emer, Özdeş ...
Molecular imaging and radionuclide therapy,
06/2019, Letnik:
28, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Abdominal aortic aneurysm (AAA) may be incidentally detected in three-phased bone scintigraphy. AAA should be diagnosed prior to the development of symptoms to perform elective repair surgery. We ...present a rare case who presented with back pain and underwent a 3-phase bone scan with Tc-99m methylene diphosphonate, which revealed a giant AAA on blood-flow and blood-pool phases in addition to bone metastases. F-18-fluorodeoxyglucose positron emission tomography/computed tomography (CT) identified hypermetabolic liver, lung, and bone lesions, and CT component of the study confirmed the diagnosis of AAA with a maximum diameter of 92 mm. The initial two phases of a 3-phase bone scintigraphy are decisive to identify vascular pathologies that may be life-threatening, if left untreated.
Tüm kanser tiplerinde olduğu gibi, prostat ve kolorektal kanserlerin oluşma gelişme ve metastaz aşamalarında, tümör hücrelerinin, kendi aralarında, çevre stromadaki normal diğer hücreler ile ...ilişkilerinin anlaşılması, immün yanıt karşısındaki tutumları ile gen ve sinyal yolaklarında meydana gelen değişikliklerinin anlaşılması çok önemlidir. Bu nedenle deneysel araştırmalar için, tümör hücre serilerinin oluşturulması, laboratuvar ortamında dokuların oluşturulması, hayvan veya insan tümör hücre veya dokularının enjeksiyon ya da implantasyon yolu ile bilimin sessiz kahramanları olan deney hayvanlarında tümör modellerinin oluşturulması ve bunların moleküler görüntülenmesi çok önemlidir. Ancak bu şekilde bu hastalıkların etkili bir tedavisi bulunabilir ya da daha oluşmadan önlenebilir hale gelir.
Three-phase bone scintigraphy is sometimes of great value in the detection of uncharacteristic metastases and assists the management of patients in terms of primary focus detection. While evaluating ...the skeletal system with whole-body bone scintigraphy, other system pathologies may also be detected incidentally. In this case, we present the extraordinary findings on the 3-phase MDP bone scintigraphy and F-FDG PET/CT imaging of the complicated bone metastases in a patient with thyroid carcinoma.
Objectives: The current study evaluates the value of cardiac hybrid imaging (CHI), performed by the fusion of functional and anatomic cardiac images, in the detection of hemodynamically significant ...coronary stenosis in cases with multiple coronary stenosis. Methods: A total of 36 patients (10 female, 26 male) in whom ischemia or infarction was detected on gated myocardial perfusion single photon emission computed tomography (gMPS) and multiple coronary stenosis were concomitantly detected on coronary computed tomography angiography (CCTA) and undergone invasive coronary angiography (ICA) was included in this study. Statistical analyses were performed using SPSS 22 Windows software. McNemar test was applied to show concordance between coronary CT angiography, ICA and CHI in the detection of anatomically or hemodynamically significant stenosis in three major coronary arteries. Comparison results of coronary arteries responsible for perfusion defects on CHI and gMPS are presented as percentages (%). Results: There was total accordance between coronary arteries leading to perfusion defects detected by gMPS and CHI in 50% of patients. It was observed a partial accordance in 36.1% of the patients. Additionally, it was also detected perfusion defects originated from side branches in 25% of the patients. Between results of CCTA and ICA, no statistically significant difference was noted in the detection of anatomically significant stenoses in the left main coronary artery, left anterior descending artery (LAD), left circumflex artery (LCx) and right coronary artery (RCA) (p=1.000, 0.070, 0.549, and 1.000, respectively). In addition, no statistically significant difference was found in the detection of anatomically and hemodynamically significant stenoses in LAD, LCx and RCA by CCTA and CHI (p=0.344, 0.629, and 0.219, respectively). No statistically significant difference was observed in the detection of anatomically and hemodynamically significant stenoses in LAD, LCx and RCA by ICA and CHI (p=0.804, 1.000, and 0.344, respectively). Conclusion: It is possible to detect hemodynamically significant coronary stenosis directly by CHI modality in patients with multiple coronary stenosis, wide perfusion defects.
Fever of unknown origin (FUO) is defined as an illness having fever which lasts at least 3 weeks of duration and is higher than 38.3 ºC on several measurements. The causes are infections, ...malignancies, noninfectious inflammatory diseases and miscellaneous. If 18FFDG-PET/CT helps the final diagnosis, it is called contributory. The aim of the study is to evaluate the predictor variables effecting a contributory PET/CT for the diagnosis.
This is a retrospective cohort study conducted between June 2006 and May 2015 including 76 patients. The evaluated predictor variables are age, sex, ESR, CRP, fibrinogen, ferritin, albumin, haemoglobin level, platelet count, total leukocyte count, neutrophil percentage, lymphocyte percentage, ALP, LDH, ALAT, ASAT, GGT, total bilirubin, CK, RF, ANA, urinanalysis, chest radiography, abdominal US, lymphadenopathy, duration of fever, comorbid diseases and previous therapies.
ESR (P=0.001), CRP (P=0.001), fibrinogen (P=0.009), lymphopenia (P<0.001), neutrophilia (P<0.001), ferritin (P<0.001), leukocytosis (P=0.003), duration of fever before PET/CT (<3 months) were found to be statistically significant for positive contribution of PET/CT results to the diagnosis. CONCLUSİONS: 18FFDG-PET/CT is helpful and contributory for the diagnosis of FUO in patients having higher levels of CRP, ESR, ferritin, fibrinogen, leukocytosis, neutrophilia and shorter durations of fever (<3 months).
ObjectivesThe aim of this study was to analyze the systolic part of the left ventricular (LV) volume curve obtained by gated myocardial perfusion imaging with the formula used in exponential decay ...and to investigate the clinical value of the results.MethodsOne hundred fifty eight patients were retrospectively enrolled in the study. The study group was divided into three groups as normal, ischemia, and infarct. The systolic portion of the LV volume curve was also analyzed using the exponential decay formula. The scintigraphic parameter obtained using this formula is called the ejection constant (Ec).ResultsThe Ec results were 1.8±0.8, 2.7±0.9, 3.5±1 in infarct, ischemia, and normal groups, respectively, and the difference in Ec results between the groups was statistically significant (p≤0.001).ConclusionIt appears that Ec may play a clinical role as a scintigraphic parameter in the evaluation of systolic functions of the left ventricle.
One of the most important causes of death is still myocardial ischemia which is caused by myocardial oxygen demand not supplied by coronary blood flow due to coronary artery disease in increased ...workload conditions. Stable coronary artery disease due to supply-demand imbalance in the myocardium caused by progressive coronary atherosclerosis detected at coronary angiography presents itself as recurrent episodes of chest pain, called angina pectoris. Unstable coronary artery disease due to plaque rupture which is associated with plaque complications accompanied by thrombosis and thrombolysis processes causes acute coronary syndromes. Besides, there is also a group in which ischemia and infarction develop without significant obstructive atherosclerotic coronary artery disease at coronary angiography. This term, called cardiac syndrome X, is used to describe the microvascular angina caused by coronary microvascular dysfunction due to structural and functional causes. Coronary microvascular disease caused by an increased vascular contraction in microvascular structures in response to exercise or pharmacologic agents, or failure of endothelium-dependent/independent vasodilatation, or a combination of such conditions, is responsible for the clinical findings in the symptomatic cases with normal coronary angiogram. In this review, the different aspects of coronary microvascular disease are aimed to be discussed in light of the current literature.
Fibrous dysplasia (FD) is a benign fibroosseous bone disorder. It has poliostotic and monostotic patterns. Monostotic FD is frequently asymptomatic and is usually discovered incidentally by ...radiologic imaging performed for other reasons. Bone scintigraphy is valuable for identifying disease extent. Craniofacial FD (CFD) is a form of the disease where lesions are limited to contiguous bones of the craniofacial skeleton. We presented a case with monostotic CFD who was detected incidentally on bone scintigraphy single-photon emission computed tomography/computerized tomography while being investigated for inflammatory arthropaties.
Stress fractures could be classified as fatigue fractures and insufficiency fractures (IF). Fatigue fractures occur when abnormal mechanical stress is applied to a normal bone, on the other hand ...insufficiency fractures occur when normal to moderate pressure is applied to a bone that has decreased resistance (Daffner and Pavlov in Am J Radiol 159:242-245, 1992). IF have been observed mainly in patients with postmenopausal osteoporosis, and are becoming more common with the increase of elderly population (Daffner and Pavlov in Am J Radiol 159:242-245, 1992). Other systemic and metabolic conditions that can result in osteopenia and IF include osteomalacia, hyperparathyroidism, hyperthyroidism, rheumatoid arthritis, fluoride treatment, diabetes mellitus, fibrous dysplasia, Paget's disease, irradiation and mechanical factors (Daffner and Pavlov in Am J Radiol 159:242-245, 1992; Soubrier et al. in Joint Bone Spine 70:209-218, 2003; Epps et al. in Am J Orthop 33:457-460, 2004; Austin and Chrissos in Orthopedics 28:795-797, 2005). In this case report, the authors present an osteoporotic woman who developed bilateral insufficiency fracture of the femoral shaft after longstanding steroid, thyroxine replacement and alendronate therapy due to partial empty sella syndrome and osteoporosis, resulting in the treatment of the fracture by inflatable intramedullary nailing.
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