Arndt‐Gottron (S‐AG) syndrome or scleromyxedema is a scarce disease characterized by a generalized papular and sclerodermoid eruption and systemic manifestations that can lead to significant ...morbid‐mortality. Interesting, S‐AG can be associated with a paraprotein. We report an exceptional scleromyxedema case associated with a benign monoclonal gammapathy in an old woman.
Fulminant lupus pneumonitis is a rare complication of SLE. We report a case of 75 years‐old male patient with SLE who developed pneumonia and severe respiratory failure requiring mechanical ...ventilation. Refractory respiratory distress complicating noninfectious fulminant lupus pneumonitis did not respond to methylprednisolone and intravenous immunoglobulin treatment.
FLP in SLE of the elderly is a rare and severe condition. Each practitioner has to focus on respiratory failure, which is severe and life‐threatening.
Tuberculous tenosynovitis of the hand is a very rare condition. Herein, we report the case of tuberculous tenosynovitis of the hand in a 32‐year‐old woman. We highlight the success of anti ...tuberculosis drugs alone without resort to surgical treatment.
T1 weighted MRI images showed thickening of flexor sheaths (A), intensely enhanced after injection of gadolinium (B), conforming with flexor tenosynovitis of the left hand.
La panniculite est une maladie inflammatoire du tissu adipeux sous-cutané rarement associée à la dermatomyosite. Elle peut survenir avant, après ou en même temps que l'atteinte musculaire. Dans la ...plupart des cas, l’évolution de la panniculite et des autres atteintes de la dermatomyosite est favorable sous traitement corticoïde et/ou immunosuppresseur. Nous rapportons le cas d'une patiente âgée de 48 ans ayant présenté des lésions de panniculite précédant de 2 mois les signes musculaires. L'atteinte cutanée était résistante au traitement corticoïde associés aux immunosuppresseurs ce qui a nécessité le recours au traitement par Immunoglobulines polyvalentes permettant ainsi une amélioration à la fois de l'atteinte cutanée et musculaire.
Lupus erythematosus panniculitis: A case report Ben Dhaou, Besma; kefi, Asma; Aydi, Zohra ...
Journal of Dermatology & Dermatologic Surgery,
07/2017, Letnik:
21, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Lupus erythematosus panniculitis (LEP), an uncommon variant in the clinicopathological spectrum of lupus erythematosus (LE), is rare. There are only a few reported series of patients with this ...condition; none in individuals of North African ancestry. LEP is characterized by inflammation of the deep dermis and subcutaneous tissue. It usually consists of nodules and hardened subcutaneous plaques on the forehead, cheeks, proximal extremities, and buttocks. Leg involvement is rare and can lead to misdiagnosis. A case of LEP, with unusual involvement of legs, is reported in a 40-year-old woman who had the diagnosis of systemic lupus erythematosus (SLE) four years ago.
Sarcoidosis is a multisystemic disorder of unknown etiology which is characterized by the formation of non-caseating granulomas in involved tissues. Cardiac involvement is one of the least common ...manifestations and it can occur at any point of time during the course of sarcoidosis. Here we present the case of 2 patients with known sarcoidosis who develop cardiac abnormalities in the absence of known primary cardiac cause. In our report, we would like to draw attention to the importance of considering heart involvement in any case with systemic sarcoidosis especially in young age.
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•Thuya essential oil composition varied significantly with phenological stage.•Essential oil from flowering stage was the most active against Botrytis cinerea.•Thuya essential oil ...reduced fungal infection on tomato detached leaflets.•Thuya essential oil reduced Botrytis cinerea infection by 54 % on tomato fruit.•Pre-treatment of tomato plants with essential oil decreased disease severity by 66 %.
Essential oils (EOs) extracted from medicinal plants gained interest in research due to their potential effectiveness as antimicrobial compounds that can substitute chemical pesticides for treatment of plant derived foods. This study aims to use Tetraclinis articulata EO to control Botrytis cinerea pre- and post-harvest infection on tomato. Tetraclinis articulata EOs extracted at vegetative, flowering and fructification stages were rich in α-pinene (8.10–21.52%), β-caryophyllene (5.17–16.10 %) and caryophyllene oxide (5.57–6.83 %) with the main chemical classes were oxygenated monoterpenes (30.50–50.86 %) and monoterpene hydrocarbons (12.19–28.96 %). The in vitro antifungal activity of EOs against B. cinerea varied with the phenological stage, with the highest activity observed at flowering stage which used subsequently. The activity of α-pinene alone or mixed with bornyl acetate according to their natural proportions at 250 μg mL−1 totally inhibited B. cinerea conidia germination. The pulverization of EO on detached leaflets at 2 mg mL−1 reduced B. cinerea necrosis to 14.50 % in comparison to only infected leaflets 76.00 %. Tetraclinis articulata EO applied as preventive treatment on tomato plants under greenhouse conditions enhanced plants growth and reduced B. cinerea infection to 17.72 % in comparison to infected and non-treated plants 52.11 %. The EO applied at 100 μg mL-1 on tomato fruit reduced infection caused by B. cinerea by 64.01 %. Tetraclinis articulata EO constitutes a promising natural product to reduce B. cinerea infections on tomato in pre- and post-harvest conditions during storage and transport.
The present work was developed to evaluate the in vitro antioxidant, antibacterial, antileishmanial and cytotoxic activities of Echium arenarium (Guss) extracts, and to analyze their phytochemical ...composition. The highest content of total phenolic compounds was obtained in the ethyl acetate extract which showed the best DPPH scavenging activity and β-carotene bleaching inhibition (IC50 = 1.1 and 9.94 μg/mL respectively). It also exhibited the highest antibacterial activity against Gram-positive bacteria (L. monocytogenes; S. aureus; MRSA, E. faecalis and B. cereus) and antileishmanial activity against L. major (IC50 = 13.91 ± 0.43 μg/mL) and L. infantum (IC50 = 9.91 ± 0.15 μg/mL). Moreover, the active extract exhibited potent antiamastigote activity (IC50 = 22.48 ± 0.14 μg/mL and 18.59 ± 0.09 μg/mL against L. major and L. infantum respectively). Cytotoxicity studies revealed low toxicity against Raw 264.7 macrophage cell line (IC50 = 145.80 ± 0.84 μg/mL, SI < 10). Luteolin-7-O-glucoside was identified as the major flavonoid component by RP-HPLC analysis. In conclusion, Echium arenarium (Guss) extract was characterized by a wide range of biological activities and could be used as a potential natural anti-infectious drug.
•Several Echium arenarium fractions showed important biological activities.•Ethyl acetate fractions showed the highest antioxidant potential.•Ethyl acetate displayed the stronger antibacterial and antileishmanial activities.•Good selectivity index and specificity for amastigote and promastigote forms.•Activity was attributed to the high content of flavonoid and especially to the luteolin-7-O-glucoside.
Eighty endophytic bacteria were isolated from healthy tissues of roots, stems, leaves and fruits of tomato plants (Lycopersicon esculentum). Four strains, named BL1, BT5, BR8 and BF11 were selected ...for their antagonism against Botrytis cinerea, a phytopathogenic fungus responsible of gray mold in several important crops, with growth inhibitory activity ranging from 27 to 53 %. Morphological, biochemical, and molecular parameters as 16S rDNA sequencing demonstrated that the selected bacterial strains were related to Bacillus species which are known to produce and secrete a lot of lipopeptides with strong inhibitory effect against pathogen mycelial growth. Electrospray mass spectrometry analysis showed that these strains produced heterogeneous mixture of antibiotics belonging to fengycin and surfactin for BL1 and BT5, to iturin and surfactin for BR8, to bacillomycin D, fengycin and surfactin for BF11. Furthermore, these bacteria exhibited biocontrol potential by reducing the disease severity when tested on detached leaflets. Based on their antifungal activity against Botrytis cinerea, these strains could be used for biological control of plant diseases.
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