Livestock production, particularly enteric methane production, contributes to greenhouse gas emissions globally. Various mitigation strategies developed to reduce enteric emissions have limited ...success. Although in vitro studies have shown a considerable reduction in methane emissions using Asparagopsis spp., no studies have been conducted to investigate the effect of any species of Asparagopsis in dairy cattle. Our objective was to evaluate quantitatively the response of cows consuming Asparagopsis armata on methane production (g/kg), yield (g/kg feed intake) and intensity (g/kg milk yield). Twelve post-peak lactating Holstein cows were randomly assigned to three treatments (control, 0.5% and 1% inclusion levels of A. armata on organic matter basis) in a 3 × 3 Latin square design with three 21-day periods. Enteric methane emissions were measured using the GreenFeed system. Methane production by cows decreased significantly by 26.4% at the low (0.5%) level of A. armata inclusion and 67.2% at the high (1%) level of inclusion. Feed intake was reduced by 10.8 and 38.0%, in cows fed the low and high level of macroalgae inclusion, respectively. Methane yield decreased significantly by 20.3 and 42.7% in cows fed diet including 0.5% and 1% A. armata inclusion levels, respectively (P = <0.0001). Methane intensity significantly decreased by 26.8% from cows fed at 0.5% level and 60% at the 1.0% A. armata inclusion level. Bromoform concentrations in milk were not significantly different between treatments. Our in vivo results showed that A. armata has potential to be used as a feed additive to reduce enteric methane emissions.
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•Methane production by cows reduced up to 67% due to seaweed inclusion in diet.•Methane emissions reduced by up to 43% when normalized by how much cows consumed.•Adjusted for milk production methane emissions reduced by up to 60%.•Hydrogen and carbon dioxide emissions increased as methane emission decreased.
A 19-year-old man presented with a 1-year history of headache, generalised body weakness, progressive memory loss, and disorientation. One month prior to admission, there was aggravation of the ...weakness of the right upper limb, with new-onset difficulty with mastication, speech impairment, apathy, and urinary incontinence. On clinical examination, the patient had a motor aphasia and a right-sided hemiparesis with increased muscle tone and hyperreflexia. A noncontrast computed tomography (CT) scan of the brain revealed large ischaemic strokes extending beyond the classical vascular territories. Cerebrospinal fluid analysis showed a mildly increased protein level. The electrocardiogram revealed an irregular sinus bradycardia. The remainder of the cardiovascular and laboratory workup was unremarkable. Considering a working diagnosis of central nervous system vasculitis, the patient was treated with aspirin, prednisolone, and physiotherapy. However, he died suddenly a few weeks later. Based on this case, we discuss the challenges of stroke management in resource-limited settings, provide practical tips for general practitioners, reflect on the potential avenues for short- and long-term action, and introduce the budding collaboration platform between the University College London, the University of Liverpool, the Queen Elizabeth Central Hospital, and the Malawi-Liverpool-Wellcome Trust Clinical Research Programme.
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