There are two active and independent lines of research that aim at quantifying the amount of information that is disclosed by computing on confidential data. Each line of research has developed its ...own notion of confidentiality: on the one hand, differential privacy is the emerging consensus guarantee used for privacy-preserving data analysis. On the other hand, information-theoretic notions of leakage are used for characterizing the confidentiality properties of programs in language-based settings. The purpose of this article is to establish formal connections between both notions of confidentiality, and to compare them in terms of the security guarantees they deliver. We obtain the following results. First, we establish upper bounds for the leakage of every ϵ-differentially private mechanism in terms of eps and the size of the mechanism's input domain. We achieve this by identifying and leveraging a connection to coding theory. Second, we construct a class of ϵ-differentially private channels whose leakage grows with the size of their input domains. Using these channels, we show that there cannot be domain-size-independent bounds for the leakage of all ϵ-differentially private mechanisms. Moreover, we perform an empirical evaluation that shows that the leakage of these channels almost matches our theoretical upper bounds, demonstrating the accuracy of these bounds. Finally, we show that the question of providing optimal upper bounds for the leakage of ϵ-differentially private mechanisms in terms of rational functions of ϵ is in fact decidable.
Intraocular metastases, especially to the retina, are uncommon in cancer patients and generally occur in an advanced phase of the disease. In patients with lung cancer, uveal metastases, in ...particular to the choroid, are the most frequent, and are associated mainly with small cell carcinoma or undifferentiated carcinoma. We report a case of unilateral retinal detachment as first sign of a moderately differentiated lung adenocarcinoma in a 55-year-old non-smoker that was admitted to the hospital for the first time complaining of a sudden visual loss in the superior fields of the left eye. A CT revealed a slight retinal enlargement of the left eye and a solid mass of about 3 centimeters behind the right pulmonary hilus. Bronchoscopic biopsies were performed with diagnosis of adenocarcinoma of the lung. The patient died after 2 months for rapid progression of the disease despite of combined chemotherapy treatment.
The possibility of measuring the proton electromagnetic form factors in the time-like region at FAIR with the \PANDA detector is discussed. Detailed simulations on signal efficiency for the ...annihilation of $\bar p +p $ into a lepton pair as well as for the most important background channels have been performed. It is shown that precision measurements of the differential cross section of the reaction $\bar p +p \to e^++ e^-$ can be obtained in a wide angular and kinematical range. The individual determination of the moduli of the electric and magnetic proton form factors will be possible up to a value of momentum transfer squared of $q^2\simeq 14$ (GeV/c)$^2$. The total $\bar p +p\to e^++e^-$ cross section will be measured up to $q^2\simeq 28$ (GeV/c)$^2$. The results obtained from simulated events are compared to the existing data. Sensitivity to the two photons exchange mechanism is also investigated.
We verified the feasibility of a multi-cycle peripheral blood progenitor cell (PBPC)-supported high-dose chemotherapy (HDC) regimen in patients with non-small cell lung cancer (NSCLC). The HDC ...regimen consisted of a single course of high-dose epirubicin given in combination with cisplatin plus filgrastim, followed by three courses of high doses of carboplatin and paclitaxel with PBPC reinfusion and filgrastim. Of the 16 enrolled patients, 13 provided an adequate number of PBPCs by a single leukapheresis, while in the three needed two procedures, with a median number of CD34+, CD34+/CD33- and CD34+/CD38- cells collected per patient was 13.5 x 10(6), 10.9 x 10(6) and 0.9 x 10(6)/kg, respectively. No toxic death occurred, and the collected PBPCs supported a rapid hematopoietic reconstitution after HDC; however, seven patients early interrupted the treatment early due to early progressive disease (n=4) or prolonged grade 3 peripheral neurotoxicity (n=3). Despite an overall response rate of 42%, the median survival for stage IV patients has been 5 months (range: 1-25+). Of two patients with stage IIIB NSCLC, one is continuously disease-free at 71+ months, while of 14 with stage IV disease, one is currently alive with disease at 25+ months. In conclusion, the combination of high-dose epirubicin with cisplatin plus filgrastim is an effective regimen in releasing large amounts of PBPCs, which can then be safely employed to support multiple courses of HDC. Multiple cycles of PBPC-supported high-dose carboplatin and paclitaxel are ineffective in treating patients with advanced NSCLC.
Abstract
A partial wave analysis of antiproton–proton annihilation data in flight at 900
$$\mathrm {MeV/}c$$
MeV
/
c
into
$${\pi ^0\pi ^0\eta }$$
π
0
π
0
η
,
$${\pi ^0\eta \eta }$$
π
0
η
η
and
...$${K^+K^-\pi ^0}$$
K
+
K
-
π
0
is presented. The data were taken at LEAR by the Crystal Barrel experiment in 1996. The three channels have been coupled together with
$$\pi \pi $$
π
π
-scattering isospin I = 0 S- and D-wave as well as I = 1 P-wave data utilizing the K-matrix approach. Analyticity is treated using Chew–Mandelstam functions. In the fit all ingredients of the K-matrix, including resonance masses and widths, were treated as free parameters. In spite of the large number of parameters, the fit results are in the ballpark of the values published by the Particle Data Group. In the channel
$${\pi ^0\pi ^0\eta }$$
π
0
π
0
η
a significant contribution of the spin exotic
$$I^G=1^-$$
I
G
=
1
-
$$J^{PC}=1^{-+}$$
J
PC
=
1
-
+
$$\pi _1$$
π
1
-wave with a coupling to
$$\pi ^0 \eta $$
π
0
η
is observed. Furthermore the contributions of
$$\phi (1020) \pi ^0$$
ϕ
(
1020
)
π
0
and
$$K^*(892)^\pm K^\mp $$
K
∗
(
892
)
±
K
∓
in the channel
$${K^+K^-\pi ^0}$$
K
+
K
-
π
0
have been studied in detail. The differential production cross section for the two reactions and the spin-density-matrix elements for the
$$\phi (1020)$$
ϕ
(
1020
)
and
$$K^*(892)^\pm $$
K
∗
(
892
)
±
have been extracted. No spin-alignment is observed for both vector mesons. The spin density matrix elements have been also determined for the spin exotic wave.
Abstract A partial wave analysis of antiproton–proton annihilation data in flight at 900 $$\mathrm {MeV/}c$$ MeV/c into $${\pi ^0\pi ^0\eta }$$ π0π0η , $${\pi ^0\eta \eta }$$ π0ηη and $${K^+K^-\pi ...^0}$$ K+K-π0 is presented. The data were taken at LEAR by the Crystal Barrel experiment in 1996. The three channels have been coupled together with $$\pi \pi $$ ππ -scattering isospin I = 0 S- and D-wave as well as I = 1 P-wave data utilizing the K-matrix approach. Analyticity is treated using Chew–Mandelstam functions. In the fit all ingredients of the K-matrix, including resonance masses and widths, were treated as free parameters. In spite of the large number of parameters, the fit results are in the ballpark of the values published by the Particle Data Group. In the channel $${\pi ^0\pi ^0\eta }$$ π0π0η a significant contribution of the spin exotic $$I^G=1^-$$ IG=1- $$J^{PC}=1^{-+}$$ JPC=1-+ $$\pi _1$$ π1 -wave with a coupling to $$\pi ^0 \eta $$ π0η is observed. Furthermore the contributions of $$\phi (1020) \pi ^0$$ ϕ(1020)π0 and $$K^*(892)^\pm K^\mp $$ K∗(892)±K∓ in the channel $${K^+K^-\pi ^0}$$ K+K-π0 have been studied in detail. The differential production cross section for the two reactions and the spin-density-matrix elements for the $$\phi (1020)$$ ϕ(1020) and $$K^*(892)^\pm $$ K∗(892)± have been extracted. No spin-alignment is observed for both vector mesons. The spin density matrix elements have been also determined for the spin exotic wave.
A partial wave analysis of antiproton–proton annihilation data in flight at 900 MeV/c into π0π0η, π0ηη and K+K-π0 is presented. The data were taken at LEAR by the Crystal Barrel experiment in 1996. ...The three channels have been coupled together with ππ-scattering isospin I = 0 S- and D-wave as well as I = 1 P-wave data utilizing the K-matrix approach. Analyticity is treated using Chew–Mandelstam functions. In the fit all ingredients of the K-matrix, including resonance masses and widths, were treated as free parameters. In spite of the large number of parameters, the fit results are in the ballpark of the values published by the Particle Data Group. In the channel π0π0η a significant contribution of the spin exotic IG=1-JPC=1-+π1-wave with a coupling to π0η is observed. Furthermore the contributions of ϕ(1020)π0 and K∗(892)±K∓ in the channel K+K-π0 have been studied in detail. The differential production cross section for the two reactions and the spin-density-matrix elements for the ϕ(1020) and K∗(892)± have been extracted. No spin-alignment is observed for both vector mesons. The spin density matrix elements have been also determined for the spin exotic wave.
A partial wave analysis of antiproton–proton annihilation data in flight at 900
MeV
/
c
into
π
0
π
0
η
,
π
0
η
η
and
K
+
K
-
π
0
is presented. The data were taken at LEAR by the Crystal Barrel ...experiment in 1996. The three channels have been coupled together with
π
π
-scattering isospin I = 0 S- and D-wave as well as I = 1 P-wave data utilizing the K-matrix approach. Analyticity is treated using Chew–Mandelstam functions. In the fit all ingredients of the K-matrix, including resonance masses and widths, were treated as free parameters. In spite of the large number of parameters, the fit results are in the ballpark of the values published by the Particle Data Group. In the channel
π
0
π
0
η
a significant contribution of the spin exotic
I
G
=
1
-
J
PC
=
1
-
+
π
1
-wave with a coupling to
π
0
η
is observed. Furthermore the contributions of
ϕ
(
1020
)
π
0
and
K
∗
(
892
)
±
K
∓
in the channel
K
+
K
-
π
0
have been studied in detail. The differential production cross section for the two reactions and the spin-density-matrix elements for the
ϕ
(
1020
)
and
K
∗
(
892
)
±
have been extracted. No spin-alignment is observed for both vector mesons. The spin density matrix elements have been also determined for the spin exotic wave.
The photoproduction of η′-mesons off different nuclei has been measured with the CBELSA/TAPS detector system for incident photon energies between 1500–2200 MeV. The transparency ratio has been ...deduced and compared to theoretical calculations describing the propagation of η′-mesons in nuclei. The comparison indicates a width of the η′-meson of the order of Γ=15–25 MeV at ρ=ρ0 for an average momentum pη′=1050 MeV/c, at which the η′-meson is produced in the nuclear rest frame. The inelastic η′N cross section is estimated to be 3–10 mb. Parameterizing the photoproduction cross section of η′-mesons by σ(A)=σ0Aα, a value of α=0.84±0.03 has been deduced.
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