A sophisticated coupled-channel analysis is presented that combines different processes: the channels
π
0
π
0
η
,
π
0
η
η
and
K
+
K
-
π
0
from
p
¯
p
annihilations, the P- and D-wave amplitudes of the
...π
η
and
π
η
′
systems produced in
π
-
p
scattering, and data from
π
π
-scattering reactions. Hence our analysis combines the data sets used in two independent previous analyses published by the Crystal Barrel experiment and by the JPAC group. Based on the new insights from these studies, this paper aims at a better understanding of the spin-exotic
π
1
resonances in the light-meson sector. By utilizing the K-matrix approach and realizing the analyticity via Chew-Mandelstam functions the amplitude of the spin-exotic wave can be well described by a single
π
1
pole for both systems,
π
η
and
π
η
′
. The mass and the width of the
π
1
-pole are measured to be
(
1623
±
47
-
75
+
24
)
MeV
/
c
2
and
(
455
±
88
-
175
+
144
)
MeV
.
Respiratory virus infections play an important role in cystic fibrosis (CF) exacerbations, but underlying pathophysiological mechanisms are poorly understood. We aimed to assess whether an ...exaggerated inflammatory response of the airway epithelium on virus infection could explain the increased susceptibility of CF patients towards respiratory viruses. We used primary bronchial and nasal epithelial cells obtained from 24 healthy control subjects and 18 CF patients. IL-6, IL-8/CXCL8, IP-10/CXCL10, MCP-1/CCL2, RANTES/CCL5 and GRO-α/CXCL1 levels in supernatants and mRNA expression in cell lysates were measured before and after infection with rhinoviruses (RV-16 and RV-1B) and RSV. Cytotoxicity was assessed by lactate dehydrogenate assay and flow cytometry. All viruses induced strong cytokine release in both control and CF cells. The inflammatory response on virus infection was heterogeneous and depended on cell type and virus used, but was not increased in CF compared with control cells. On the contrary, there was a marked trend towards lower cytokine production associated with increased cell death in CF cells. An exaggerated inflammatory response to virus infection in bronchial epithelial cells does not explain the increased respiratory morbidity after virus infection in CF patients.
The photoproduction of omega mesons on nuclei has been investigated using the Crystal Barrel/TAPS experiment at the ELSA tagged photon facility in Bonn. The aim is to study possible in-medium ...modifications of the omega meson via the reaction gamma + A --> omega + X --> pi(0)gamma + X('). Results obtained for Nb are compared to a reference measurement on a LH2 target. While for recoiling, long-lived mesons (pi(0), eta, and eta;(')), which decay outside of the nucleus, a difference in the line shape for the two data samples is not observed, we find a significant enhancement towards lower masses for omega mesons produced on the Nb target. For momenta less than 500 MeV/c an in-medium omega meson mass of M(medium) = 722(+4)(-4)(stat)+35-5(syst) MeV/c(2) has been deduced at an estimated average nuclear density of 0.6rho(0).
Information on hadron properties in the nuclear medium has been derived from the photoproduction of omega mesons on the nuclei C, Ca, Nb, and Pb using the Crystal Barrel/TAPS detector at the ELSA ...tagged photon facility in Bonn. The dependence of the omega-meson cross section on the nuclear mass number has been compared with three different types of models: a Glauber analysis, a Boltzmann-Uehling-Uhlenbeck analysis of the Giessen theory group, and a calculation by the Valencia theory group. In all three cases, the inelastic omega width is found to be 130-150 MeV/c(2) at normal nuclear matter density for an average 3-momentum of 1.1 GeV/c. In the rest frame of the omega meson, this inelastic omega width corresponds to a reduction of the omega lifetime by a factor approximately 30. For the first time, the momentum dependent omegaN cross section has been extracted from the experiment and is in the range of 70 mb.
We conducted a prospective randomized clinical trial to assess the mobilizing efficacy of filgrastim, lenograstim and molgramostim following a disease-specific chemotherapy regimen. Mobilization ...consisted of high-dose cyclophosphamide in 45 cases (44%), and cisplatin/ifosfamide/etoposide or vinblastine in 22 (21%), followed by randomization to either filgrastim or lenograstim or molgramostim at 5 microg/kg/day. One hundred and three patients were randomized, and 82 (79%) performed apheresis. Forty-four (43%) patients were chemonaive, whereas 59 (57%) were pretreated. A median number of one apheresis per patient (range, 1-3) was performed. The median number of CD34+ cells obtained after mobilization was 8.4 x 10(6)/kg in the filgrastim arm versus 5.8 x 10(6)/kg in the lenograstim arm versus 4.0 x 10(6)/kg in the molgramostim arm (P=0.1). A statistically significant difference was observed for the median number of days of growth factor administration in favor of lenograstim (12 days) versus filgrastim (13 days) and molgramostim (14 days) (P<0.0001) and for the subgroup of chemonaive patients (12 days) versus pretreated patients (14 days) (P<0.001). In conclusion, all three growth factors were efficacious in mobilizing peripheral blood progenitor cells with no statistically significant difference between CD34+ cell yield and the different regimens, and the time to apheresis is likely confounded by the different mobilization regimens.
A sophisticated coupled-channel analysis is presented that combines different processes: the channels Formula omitted, Formula omitted and Formula omitted from Formula omitted annihilations, the P- ...and D-wave amplitudes of the Formula omitted and Formula omitted systems produced in Formula omitted scattering, and data from Formula omitted-scattering reactions. Hence our analysis combines the data sets used in two independent previous analyses published by the Crystal Barrel experiment and by the JPAC group. Based on the new insights from these studies, this paper aims at a better understanding of the spin-exotic Formula omitted resonances in the light-meson sector. By utilizing the K-matrix approach and realizing the analyticity via Chew-Mandelstam functions the amplitude of the spin-exotic wave can be well described by a single Formula omitted pole for both systems, Formula omitted and Formula omitted. The mass and the width of the Formula omitted-pole are measured to be Formula omitted and Formula omitted.
Abstract A sophisticated coupled-channel analysis is presented that combines different processes: the channels $${\pi ^0\pi ^0\eta }$$ π 0 π 0 η , $${\pi ^0\eta \eta }$$ π 0 η η and $${K^+K^-\pi ...^0}$$ K + K - π 0 from $${{\bar{p}}p}$$ p ¯ p annihilations, the P- and D-wave amplitudes of the $$\pi \eta $$ π η and $$\pi \eta ^\prime $$ π η ′ systems produced in $$\pi ^-p$$ π - p scattering, and data from $${\pi \pi }$$ π π -scattering reactions. Hence our analysis combines the data sets used in two independent previous analyses published by the Crystal Barrel experiment and by the JPAC group. Based on the new insights from these studies, this paper aims at a better understanding of the spin-exotic $$\pi _1$$ π 1 resonances in the light-meson sector. By utilizing the K-matrix approach and realizing the analyticity via Chew-Mandelstam functions the amplitude of the spin-exotic wave can be well described by a single $$\pi _1$$ π 1 pole for both systems, $$\pi \eta $$ π η and $$\pi \eta ^\prime $$ π η ′ . The mass and the width of the $$\pi _1$$ π 1 -pole are measured to be $$(1623 \, \pm \, 47 \, ^{+24}_{-75})\, \mathrm {MeV/}c^2$$ ( 1623 ± 47 - 75 + 24 ) MeV / c 2 and $$(455 \, \pm 88 \, ^{+144}_{-175})\, \mathrm {MeV}$$ ( 455 ± 88 - 175 + 144 ) MeV .
Abstract
A sophisticated coupled-channel analysis is presented that combines different processes: the channels
$${\pi ^0\pi ^0\eta }$$
π
0
π
0
η
,
$${\pi ^0\eta \eta }$$
π
0
η
η
and
$${K^+K^-\pi ...^0}$$
K
+
K
-
π
0
from
$${{\bar{p}}p}$$
p
¯
p
annihilations, the P- and D-wave amplitudes of the
$$\pi \eta $$
π
η
and
$$\pi \eta ^\prime $$
π
η
′
systems produced in
$$\pi ^-p$$
π
-
p
scattering, and data from
$${\pi \pi }$$
π
π
-scattering reactions. Hence our analysis combines the data sets used in two independent previous analyses published by the Crystal Barrel experiment and by the JPAC group. Based on the new insights from these studies, this paper aims at a better understanding of the spin-exotic
$$\pi _1$$
π
1
resonances in the light-meson sector. By utilizing the K-matrix approach and realizing the analyticity via Chew-Mandelstam functions the amplitude of the spin-exotic wave can be well described by a single
$$\pi _1$$
π
1
pole for both systems,
$$\pi \eta $$
π
η
and
$$\pi \eta ^\prime $$
π
η
′
. The mass and the width of the
$$\pi _1$$
π
1
-pole are measured to be
$$(1623 \, \pm \, 47 \, ^{+24}_{-75})\, \mathrm {MeV/}c^2$$
(
1623
±
47
-
75
+
24
)
MeV
/
c
2
and
$$(455 \, \pm 88 \, ^{+144}_{-175})\, \mathrm {MeV}$$
(
455
±
88
-
175
+
144
)
MeV
.
A partial wave analysis of antiproton-proton annihilation data in flight at 900 Formula omitted into Formula omitted, Formula omitted and Formula omitted is presented. The data were taken at LEAR by ...the Crystal Barrel experiment in 1996. The three channels have been coupled together with Formula omitted-scattering isospin I = 0 S- and D-wave as well as I = 1 P-wave data utilizing the K-matrix approach. Analyticity is treated using Chew-Mandelstam functions. In the fit all ingredients of the K-matrix, including resonance masses and widths, were treated as free parameters. In spite of the large number of parameters, the fit results are in the ballpark of the values published by the Particle Data Group. In the channel Formula omitted a significant contribution of the spin exotic Formula omitted Formula omitted Formula omitted-wave with a coupling to Formula omitted is observed. Furthermore the contributions of Formula omitted and Formula omitted in the channel Formula omitted have been studied in detail. The differential production cross section for the two reactions and the spin-density-matrix elements for the Formula omitted and Formula omitted have been extracted. No spin-alignment is observed for both vector mesons. The spin density matrix elements have been also determined for the spin exotic wave.
PDF
