This paper presents the design of a front-end circuit for monolithic active pixel sensors. The circuit operates with a sensor featuring a small, low-capacitance (< 2 fF) collection electrode and is ...integrated in the DPTS chip, a proof-of-principle prototype of 1.5 mm × 1.5 mm including a matrix of 32 × 32 pixels with a pitch of 15 μm. The chip is implemented in the 65 nm imaging technology from the Tower Partners Semiconductor Co. foundry and was developed in the framework of the EP-R&D program at CERN to explore this technology for particle detection. The front-end circuit has an area of 42 μm 2 and can operate with a power consumption as low as 12 nW. Measurements on the prototype relevant to the front-end will be shown to support its design.
Abstract
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database ...and the PubMed database of citations and abstracts for published life science journals. The Entrez system provides search and retrieval operations for most of these data from 39 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. New resources released in the past year include PubMed Data Management, RefSeq Functional Elements, genome data download, variation services API, Magic-BLAST, QuickBLASTp, and Identical Protein Groups. Resources that were updated in the past year include the genome data viewer, a human genome resources page, Gene, virus variation, OSIRIS, and PubChem. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
Microinclusions of ore minerals were found and studied in grains of native gold for characterization of the mineralogy of placer gold of the South Urals. One hundred ten unrounded and poorly rounded ...grains with a size of 1–2 mm from eight placer zones were studied. Microinclusions of ore minerals were detected in six placers of the Miass zone. The list of minerals includes sulfides, arsenides, Cu-bearing Au, and PGEs. All microinclusions show links to certain deposits of ore gold and chromite occurrences. It is suggested that the northern flanges of the Talovsky and Nurali massifs containing gold placers with PGEs require a search for PGE mineralization.
Purpose. Development of methodology and experimental studies of the layout of the active screening of technogenic power frequency magnetic fields with different control algorithms with a single coil ...magnetic executive body. Methodology. In the course of mathematical modeling to determine geometrical size of the magnetic coil executive body based on the size of the protected area, and the configuration of the coil magnetic executive body is determined based on the required uniformity of the magnetic field distribution in the protected area. Results. Experimental studies of open, closed and combined systems of active screening of technogenic power frequency magnetic fields with a single coil magnetic executive body. Originality. For the first time experimentally confirmed the possibility of reducing the level of induction of man-made power frequency magnetic fields in a given area 3-5 times with a single coil magnetic executive body.. The possibility of reducing the level of the magnetic field in a limited area of the space by 15-20 times Practical value. On the basis of the calculations the layout of active screening of technogenic power frequency magnetic fields with different control algorithms with a single coil magnetic executive body has been made.
The study was designed to assess clinical efficiency and safety of nebivolol in patients with cardiovascular problems and chronic obstructive pulmonary disease. It included 50 patients of whom 25 ...were given daily 5 and 25 mg of nebivolol and 80-100 mg of verapamil. Nebivolol was shown to significantly reduce arterial pressure, heart rate, and the number of ventricular extrasystoles. The drug was well tolerated by the patients and had no adverse effect on bronchial patiency.
Forty-five patients with coronary heart disease and various forms of ventricular arrhythmias (25 men and 20 women aged 42 to 73) were examined. The use of complex therapy with emoxipin and preductal ...in a combination with antiarrhythmic agents potentated the action of these preparations. The application of emoxipin resulted in a longer positive effect.
Antiarrhythmic therapy of patients with disturbed automatism of the sinus node and impaired atrioventricular conductance may be complicated by hemodynamically significant bradycardias and ...contraindications for implantation of a cardiac electrical stimulator This study aimed at estimating effect of antiarrhythmic therapy with allapinin on the function of sinus and atrioventricular nodes. It included 20 patients (mean age 37.5+-2.3 years) with disturbed cardiac rhythm and sinus node dysfunction treated with allapinin (37.5 - 50 mg/d per os). This therapy had well apparent antiarrhythmic effect manifest as improvement of supraventricular and ventricular ectopic activities in the absence of negative influence on the function of sinus and atrioventricular nodes.
We studied effect of the neoplastic process and surgical treatment on parameters of the oxidative system in patients with stomach cancer including serum and gastric tissue levels of malonic ...dialdehyde, lactic and pyruvic acids in stage I-IV malignancy before and after radical surgery. The development and generalization of the neoplastic process are associated with the activation of oxidative reactions leading to endotoxicosis. Specific anticarcinogenic treatments (including surgery) aggravate changes in the oxidative systems and further deteriorate quality of life and tolerance of the treatment.
Мета. Розробка методики і проведення експериментальних досліджень макета системи активного екранування техногенного магнітного поля промислової частоти з різними алгоритмами управління за допомогою ...однієї обмотки магнітного виконавчого органу. Методика. В ході математичного моделювання визначаються геометричні розміри обмотки магнітного виконавчого органу виходячи з розмірів області, в якій здійснюється захист, а конфігурація обмотки магнітного виконавчого органу визначається виходячи з необхідної рівномірності розподілу магнітного поля. Результати. Проведено експериментальні дослідження розімкнутих, замкнутих і комбінованих систем активного екранування техногенного магнітного поля промислової частоти з однією обмоткою магнітного виконуючого органу. Наукова новизна. Вперше експериментально підтверджена можливість зменшення рівня індукції техногенного магнітного поля промислової частоти в заданій зоні в 3-5 раз з однією обмоткою магнітного виконавчого органу. Показана можливість зменшення рівня індукції магнітного поля в обмеженій зоні розглянутого простору в 15-20 раз. Практична значимість. На підставі проведених розрахунків був виготовлений макет системи активного екранування техногенного магнітного поля промислової частоти з різними алгоритмами управління за допомогою однієї обмотки магнітного виконуючого органу.