Brain signals can provide the basis for a non-muscular communication and control system, a brain-computer interface (BCI), for people with motor disabilities. A common approach to creating BCI ...devices is to decode kinematic parameters of movements using signals recorded by intracortical microelectrodes. Recent studies have shown that kinematic parameters of hand movements can also be accurately decoded from signals recorded by electrodes placed on the surface of the brain (electrocorticography (ECoG)). In the present study, we extend these results by demonstrating that it is also possible to decode the time course of the flexion of individual fingers using ECoG signals in humans, and by showing that these flexion time courses are highly specific to the moving finger. These results provide additional support for the hypothesis that ECoG could be the basis for powerful clinically practical BCI systems, and also indicate that ECoG is useful for studying cortical dynamics related to motor function.
Signals from the brain could provide a non-muscular communication and control system, a brain-computer interface (BCI), for people who are severely paralyzed. A common BCI research strategy begins by ...decoding kinematic parameters from brain signals recorded during actual arm movement. It has been assumed that these parameters can be derived accurately only from signals recorded by intracortical microelectrodes, but the long-term stability of such electrodes is uncertain. The present study disproves this widespread assumption by showing in humans that kinematic parameters can also be decoded from signals recorded by subdural electrodes on the cortical surface (ECoG) with an accuracy comparable to that achieved in monkey studies using intracortical microelectrodes. A new ECoG feature labeled the local motor potential (LMP) provided the most information about movement. Furthermore, features displayed cosine tuning that has previously been described only for signals recorded within the brain. These results suggest that ECoG could be a more stable and less invasive alternative to intracortical electrodes for BCI systems, and could also prove useful in studies of motor function.
Prey responses to predator cues are graded in intensity in accordance with the degree of threat presented by the predator. In systems in which prey gather information on predators by using chemicals, ...prey often respond more to the odor of predators that have consumed conspecifics, as opposed to heterospecifics. We investigated the response of a prey species, the mud crab,
Panopeus herbstii
, to urine of blue crab,
Callinectes sapidus
, fed mud crabs or oysters. Behavioral analysis was combined with metabolomics to characterize bioactive deterrents in the urine of predators fed different diets. Urine from blue crabs fed oysters or mud crabs depressed mud crab foraging when presented singly, with the urine derived from a mud crab diet being more potent. The magnitude of foraging depression increased with urine concentration. When urine from blue crabs fed oysters or mud crabs was combined, response to the urine mixture was no different from that to urine derived only from a mud crab diet. Metabolomics analysis indicated diet-dependent differences were related to a set of shared spectral features that differed in concentration in the respective urines, likely consisting of aromatic compounds, amino acids, and lipids. Taken together, these results suggest mud crabs distinguish diet of, and therefore the risk imposed by, predators through detection of a suite of compounds that together represent what the predator has recently consumed.
Context.
As evidenced by recent survey results, the majority of asteroids are slow rotators (spin periods longer than 12 h), but lack spin and shape models because of selection bias. This bias is ...skewing our overall understanding of the spins, shapes, and sizes of asteroids, as well as of their other properties. Also, diameter determinations for large (>60 km) and medium-sized asteroids (between 30 and 60 km) often vary by over 30% for multiple reasons.
Aims.
Our long-term project is focused on a few tens of slow rotators with periods of up to 60 h. We aim to obtain their full light curves and reconstruct their spins and shapes. We also precisely scale the models, typically with an accuracy of a few percent.
Methods.
We used wide sets of dense light curves for spin and shape reconstructions via light-curve inversion. Precisely scaling them with thermal data was not possible here because of poor infrared datasets: large bodies tend to saturate in WISE mission detectors. Therefore, we recently also launched a special campaign among stellar occultation observers, both in order to scale these models and to verify the shape solutions, often allowing us to break the mirror pole ambiguity.
Results.
The presented scheme resulted in shape models for 16 slow rotators, most of them for the first time. Fitting them to chords from stellar occultation timings resolved previous inconsistencies in size determinations. For around half of the targets, this fitting also allowed us to identify a clearly preferred pole solution from the pair of two mirror pole solutions, thus removing the ambiguity inherent to light-curve inversion. We also address the influence of the uncertainty of the shape models on the derived diameters.
Conclusions.
Overall, our project has already provided reliable models for around 50 slow rotators. Such well-determined and scaled asteroid shapes will, for example, constitute a solid basis for precise density determinations when coupled with mass information. Spin and shape models in general continue to fill the gaps caused by various biases.
We often look at and sometimes reach for visible targets. Looking at a target is fast and relatively easy. By comparison, reaching for an object is slower and is associated with a larger cost. We ...hypothesized that, as a result of these differences, abrupt visual onsets may drive the circuits involved in saccade planning more directly and with less intermediate regulation than the circuits involved in reach planning. To test this hypothesis, we recorded discharge activity of neurons in the parietal oculomotor system (area LIP) and in the parietal somatomotor system (area PRR) while monkeys performed a visually guided movement task and a choice task. We found that in the visually guided movement task LIP neurons show a prominent transient response to target onset. PRR neurons also show a transient response, although this response is reduced in amplitude, is delayed, and has a slower rise time compared with LIP. A more striking difference is observed in the choice task. The transient response of PRR neurons is almost completely abolished and replaced with a slow buildup of activity, while the LIP response is merely delayed and reduced in amplitude. Our findings suggest that the oculomotor system is more closely and obligatorily coupled to the visual system, whereas the somatomotor system operates in a more discriminating manner.
The use of chemical compounds to suppress the growth of competitors is a competitive strategy known as allelopathy that can be readily observed with many phytoplankton species in laboratory studies. ...However, it is unclear how these allelopathic interactions are altered when the complexity of the system is increased to more closely mimic natural conditions. In the present study, we conducted laboratory experiments to decipher how the identity, abundance, and growth stage of competitors affect the outcome of allelopathic interactions with the red tide dinoflagellateKarenia brevis. Multiple chemical compounds produced byK. breviswere found to inhibit the growth of 4 phytoplankton competitors, although these competitors were susceptible to different combinations of compounds. We found that physiological state and cell concentration of competitors were important determinants of allelopathy, with early-stage (lag phase) cells more vulnerable to allelopathic effects than later growth stages for the diatomSkeletonema grethae. Despite being allelopathic to multiple competitors in the laboratory, in a microcosm experiment using plankton field assemblages, extracellular extracts of 2 strains ofK. brevishad no effects on some taxa although they stimulated the growth of some diatoms. This suggests that in a species-rich ecological community under oligotrophic conditions, the relative importance ofK. brevisallelopathy may not be as high as most laboratory studies predict.
The 9 month long 2011-2012 eruption of Cordón Caulle (Southern Andes, Chile) is the best instrumentally recorded rhyolitic eruption to date and the first time that the effusion of a rhyolitic flow ...has been observed in detail. We use Interferometric Synthetic Aperture Radar (InSAR), with time-lapse digital elevation models (DEMs) and numerical models to study the dynamics of coupled magma reservoir deflation and lava effusion. InSAR recorded 2.2-2.5 m of subsidence after the first three days of the eruption, which can be modeled using a spheroidal magma reservoir at a depth of ∼5 km, ∼20 km long, and with a pressure drop of 20-30 MPa. The source is elongated in the NW-SE direction and its large dimensions imply a large plumbing system active throughout the eruption and spanning neighboring volcanoes, with a slight change in the geometry halfway through the effusive phase. TanDEM-X and Pléiades DEMs record the extrusion of both the rhyolitic lava flow and the intrusion of a shallow laccolith around the eruptive vent after the third day of the eruption, with a total volume of ∼1.45 km3 DRE. The laccolith was emplaced during the first month of the eruption, during both the explosive and effusive stages of the eruption. Both the reservoir pressure drop and the extruded volume time series follow quasi-exponential trends, and can be explained by a model that couples the reservoir pressure decrease, time- and pressure-dependent variations in the magma properties inside of the reservoir, and conduit flow. This model predicts both the temporal evolution and amplitude of both time series during the effusive phase, and a magma compressibility of ∼10−10 Pa−1, half the reported compressibility of the magma of the sub-Plinian explosive phase. Further, we estimate that the reservoir contained 1-3 wt.% dissolved H2O at the onset of lava effusion, with no exsolved CO2 and H2O in the reservoir throughout the effusive phase. This implies that the magma was significantly degassed after the explosive phase. The remaining volatiles in the magma after the explosive stage might have caused magma fragmentation, consistent with the hybrid explosive-effusive style observed during the waning of the eruption.
•InSAR records deflation of a prolate spheroidal reservoir at a depth of ∼5 km.•TanDEM-X DEMs record erupted lava flow and the intrusion of a shallow laccolith with a total volume of 1.2 km3 DRE.•Time series of reservoir pressure drop and extruded volume can be modeled by a coupled reservoir - conduit flow model.•The model predicts a gas poor magma and no exsolved gas phase in the reservoir.•The temporal evolution of the eruption can be forecasted using InSAR and DEM data.
Brown seaweeds (Fucales) produce phlorotannins that are often considered chemical defenses against herbivores. The many correlative and fewer direct tests conducted have shown effects of ...phlorotannins on herbivore feeding behavior to be variable. In an attempt to clarify the roles of phlorotannins versus other metabolites in defending brown algae, we conducted bioassay-guided fractionation of herbivore-deterrent extracts from the commonly studied brown alga Fucus vesiculosus. Feeding by the amphipods Ampithoe valida and A. longimana and the sea urchin Arbacia punctulata was suppressed by crude and water-soluble extracts of F. vesiculosus, but this deterrence was lost following storage or fractionation of the active, water-soluble extract. Phlorotannins in these extracts did not decompose in parallel with the loss of feeding deterrence. F. vesiculosus phlorotannins were fed to herbivores at 3 to 12x the isolated yield (or 4.2 to 16.8% of plant dry mass). No herbivore was deterred from feeding by concentrations of 3 or 6x, but A. valida (the only test herbivore that readily consumes F. vesiculosus in the field) was deterred at 12 x isolated yield. When juvenile A. valida were raised on an artificial diet containing F. vesiculosus phlorotannins at 3 x isolated yield, the phlorotannin-rich diet significantly enhanced, rather than reduced, amphipod survivorship and growth relative to an equivalent diet without phlorotannins. Females ovulated only on the phlorotannin-rich diet. Compounds other than phlorotannins appear to defend the F. vesiculosus populations we investigated, but we were unable to identify these unstable compounds.
Interactions among microscopic planktonic organisms underpin the functioning of open ocean ecosystems. With few exceptions, these organisms lack advanced eyes and thus rely largely on chemical ...sensing to perceive their surroundings. However, few of the signaling molecules involved in interactions among marine plankton have been identified. We report a group of eight small molecules released by copepods, the most abundant zooplankton in the sea, which play a central role in food webs and biogeochemical cycles. The compounds, named copepodamides, are polar lipids connecting taurine via an amide to isoprenoid fatty acid conjugate of varying composition. The bloom-forming dinoflagellate Alexandrium minutum responds to pico- to nanomolar concentrations of copepodamides with up to a 20-fold increase in production of paralytic shellfish toxins. Different copepod species exude distinct copepodamide blends that contribute to the species-specific defensive responses observed in phytoplankton. The signaling system described here has far reaching implications for marine ecosystems by redirecting grazing pressure and facilitating the formation of large scale harmful algal blooms.
Significance We report the chemical basis for a critical question in ocean science: how do single-celled algae, which are responsible for almost half of Earth's photosynthesis, sense their environment to respond appropriately to the lethal threat of predation? The increasing frequency of toxic algal blooms, with worldwide consequences to human health, fisheries, and marine ecosystem functioning, has garnered much attention in recent years, but it has remained unclear how algal toxicity is regulated. With the current paper, we show that substantial (20×) induction of toxicity occurs when one species of algae is exposed to a family of previously unknown chemical cues from predatory zooplankton (copepods). The copepodamides represent the first discovery, to our knowledge, of chemical cues mediating interactions between marine zooplankton and their prey.
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