We investigate the transport of a Fermi gas with unitarity-limited interactions across the superfluid phase transition, probing its response to a direct current (dc) drive through a tunnel junction. ...As the superfluid critical temperature is crossed from below, we observe the evolution from a highly nonlinear to an Ohmic conduction characteristic, associated with the critical breakdown of the Josephson dc current induced by pair condensate depletion. Moreover, we reveal a large and dominant anomalous contribution to resistive currents, which reaches its maximum at the lowest attained temperature, fostered by the tunnel coupling between the condensate and phononic Bogoliubov-Anderson excitations. Increasing the temperature, while the zeroing of supercurrents marks the transition to the normal phase, the conductance drops considerably but remains much larger than that of a normal, uncorrelated Fermi gas tunneling through the same junction. We attribute such enhanced transport to incoherent tunneling of sound modes, which remain weakly damped in the collisional hydrodynamic fluid of unpaired fermions at unitarity.
In quantum fluids, the quantization of circulation forbids the diffusion of a vortex swirling flow seen in classical viscous fluids. Yet, accelerating quantum vortices may lose their energy into ...acoustic radiations
, similar to the way electric charges decelerate on emitting photons. The dissipation of vortex energy underlies central problems in quantum hydrodynamics
, such as the decay of quantum turbulence, highly relevant to systems as varied as neutron stars, superfluid helium and atomic condensates
. A deep understanding of the elementary mechanisms behind irreversible vortex dynamics has been a goal for decades
, but it is complicated by the shortage of conclusive experimental signatures
. Here we address this challenge by realizing a programmable vortex collider in a planar, homogeneous atomic Fermi superfluid with tunable inter-particle interactions. We create on-demand vortex configurations and monitor their evolution, taking advantage of the accessible time and length scales of ultracold Fermi gases
. Engineering collisions within and between vortex-antivortex pairs allows us to decouple relaxation of the vortex energy due to sound emission and that due to interactions with normal fluid (that is, mutual friction). We directly visualize how the annihilation of vortex dipoles radiates a sound pulse. Further, our few-vortex experiments extending across different superfluid regimes reveal non-universal dissipative dynamics, suggesting that fermionic quasiparticles localized inside the vortex core contribute significantly to dissipation, thereby opening the route to exploring new pathways for quantum turbulence decay, vortex by vortex.
Summary Objectives Symptomatic degenerative disc disease (DDD) is associated with neovascularization and nerve ingrowth into intervertebral discs (IVDs). Notochordal cells (NCs) are key cells that ...may lead to regeneration of IVDs. However, their activities under conditions of hypoxia, the real environment of IVD, are not well known. We hypothesized that NCs may inhibit neovascularization by interacting with endothelial cells (ECs) under hypoxia. Design Human IVDs were isolated and cultured to produce nucleus pulposus (NP) cell conditioned medium (NPCM). Immortalized human microvascular ECs were cultured in NPCM with notochordal cell-rich rabbit nucleus pulposus cells (rNC) under hypoxia. Vascular endothelial growth factor (VEGF), vascular cell adhesion molecule (VCAM), and interleukin-8 (IL-8) were analyzed by ELISA. Focal adhesion kinase (FAK), filamentous actin (F-actin), and platelet-derived growth factor (PDGF) were evaluated to investigate EC activity. Wound-healing migration assays were performed to examine EC migration. Results The VEGF level of EC cells cultured in NPCM was significantly higher under hypoxia compared to normoxia. VEGF expression was significantly decreased, and FAK, F-actin, PDGF expression were inhibited when ECs were cocultured with rNCs under hypoxia. ECs cocultured with rNC in NPCM showed significantly decreased migratory activity compared to those without rNC under hypoxia. Conclusions The angiogenic capacity of ECs was significantly inhibited by NCs under hypoxia via a VEGF-related pathway. Our results suggest that NCs may play a key role in the development of IVDs by inhibiting vascular growth within the disc, and this may be a promising novel therapeutic strategy for targeting vascular ingrowth in symptomatic DDD.
A gas junction
In superconductors, electrons form a macroscopic wave function that has a definite phase. If two superconductors with different wave function phases are placed in contact with each ...other through an insulating link, a current will flow through this so-called Josephson's junction without any external voltage. Luick
et al.
and Kwon
et al.
observed an analogous phenomenon in a setup that involved two reservoirs of superfluid Fermi gases. Both groups measured the so-called current-phase relation: the dependence of the magnitude of the current on the relative phase. By tuning an external magnetic field, they were able to study how the interactions between fermions affected the nature of the superfluid state.
Science
, this issue p.
89
, p.
84
A Josephson junction was created between two Fermi gas superfluids.
The direct-current (dc) Josephson effect provides a phase-sensitive tool for investigating superfluid order parameters. We report on the observation of dc Josephson supercurrents in strongly interacting fermionic superfluids across a tunneling barrier in the absence of any applied potential difference. For sufficiently strong barriers, we observed a sinusoidal current-phase relation, in agreement with Josephson’s seminal prediction. We mapped out the zero-resistance state and its breakdown as a function of junction parameters, extracting the Josephson critical current behavior. By comparing our results with an analytic model, we determined the pair condensate fraction throughout the Bardeen-Cooper-Schrieffer–Bose-Einstein condensation crossover. Our work suggests that coherent Josephson transport may be used to pin down superfluid order parameters in diverse atomic systems, even in the presence of strong correlations.
This paper presents multiscale-based failure criteria to predict the failure of polymer composites with any shape of defect. The multiscale technique consists of bi-directional processes called ...upscaling and downscaling processes to link two different length scales. One is the microscale at the fiber and matrix material level, and the other is the macroscale at the homogenized composite material level. Failure criteria are applied to the microscale level such as micro-stresses and/or micro-strains occurring at the fiber and matrix material level. Recently proposed unified failure criteria are applied to the micro-stresses and/or micro-strains to predict failure at a notch. The new failure criteria have two parts, and they can be applied to any shape of defect. One is the stress or strain condition, and the other is the stress or strain gradient condition. For failure to occur, both conditions must be satisfied simultaneously. The failure criteria provide not only failure locations but also directions of failure propagation.
We report on a novel method for the photoassociation of strongly polar trilobite Rydberg molecules. This exotic ultralong-range dimer, consisting of a ground-state atom bound to the Rydberg electron ...via electron-neutral scattering, inherits its polar character from the admixture of high-angular-momentum electronic orbitals. The absence of low-L character hinders standard photoassociation techniques. Here, we show that for suitable principal quantum numbers the resonant coupling of the orbital motion with the nuclear spin of the perturber, mediated by electron-neutral scattering, hybridizes the trilobite molecular potential with the more conventional S-type molecular state. This provides a general path to associate trilobite molecules with large electric dipole moments, as demonstrated via high-resolution spectroscopy. We find a dipole moment of 135(45) D for the trilobite state. Our results are compared to theoretical predictions based on a Fermi model.
Persistent currents in annular geometries have played an important role in disclosing the quantum phase coherence of superconductors and mesoscopic electronic systems. Ultracold atomic gases in ...multiply connected traps also exhibit long-lived supercurrents and have attracted much interest both for fundamental studies of superfluid dynamics and as prototypes for atomtronics circuits. Here, we report on the realization of supercurrents in homogeneous, tunable fermionic rings. We gain exquisite, rapid control over quantized persistent currents in all regimes of the BCS-BEC crossover through a universal phase-imprinting technique, attaining on-demand circulations w as high as 9. High-fidelity readout of the superfluid circulation state is achieved by exploiting an interferometric protocol, which also yields local information about the superfluid phase around the ring. In the absence of externally introduced perturbations, we find the induced metastable supercurrents to be as long-lived as the atomic sample. Conversely, we trigger and inspect the supercurrent decay by inserting a single small obstacle within the ring. For circulations higher than a critical value, the quantized current is observed to dissipate via the emission of vortices, i.e., quantized phase slips, which we directly image, in good agreement with numerical simulations. The critical circulation at which the superflow becomes unstable is found to depend starkly on the interaction strength, taking its maximum value for the unitary Fermi gas. Our results demonstrate fast and accurate control of quantized collective excitations in a macroscopic quantum system and establish strongly interacting fermionic superfluids as excellent candidates for atomtronics applications.
Background Medial ulnar collateral ligament (UCL) injuries of the elbow that require surgical management are uncommon. There is growing evidence, however, suggesting that the incidence of UCL ...reconstruction (UCLR) procedures is rapidly increasing. We sought to quantify the incidence of age-related trends for UCLR from 2003 to 2014 and subsequently to project future trends through 2025. We hypothesized that as the total number of UCLRs performed increased, a disproportionate incidence among younger patients would be observed. Methods New York State's Statewide Planning and Research Cooperative System database was queried from 2003 to 2014 to identify individuals between 10 and 40 years old undergoing UCLR. Poisson regression was used to develop future projections for UCLR and New York State population through 2025, and incidence estimates per 100,000 people were calculated. Results In New York State between 2003 and 2014, there were 890 patients who underwent UCLR, with average annual incidence per 100,000 people equaling 6.3 ± 2.8 for ages 15 to 19 years, significantly greater than for all other age groups ( P < .001). Projections from 2015 through 2025 suggest that incidence in 15- to 19-year-olds and 20- to 24-year-olds will continue to rapidly increase while rates for other age groups will remain relatively stable. Conclusions The number of UCLRs performed between 2003 and 2014 increased by 343%, and a disproportionate trend in average annual incidence for patients between 15 and 19 years old was observed. As our review of the literature questioned outcomes in adolescent athletes after UCLR, continued attempts at preventing these injuries in the young throwing athlete remain paramount.
Currently, the characteristics of carotid plaques are considered important factors for identifying subjects at high risk of stroke. This study aimed to test the hypothesis that carotid plaque ...composition assessed by CTA is associated with an increased risk of future major adverse cardiovascular events among asymptomatic subjects with moderate-to-severe carotid artery stenosis.
This single-center, retrospective cohort study included 194 carotid plaques from 176 asymptomatic subjects with moderate-to-severe carotid artery stenosis. The association of CTA-determined plaque composition with the risk of subsequent adverse cardiovascular events was analyzed.
During a median follow-up of 41 months, the adverse cardiovascular event incidence among 194 carotid plaques was 19.6%. There were significant differences in plaque Hounsfield units (
< .001) and spotty calcium presence (
< .001) between carotid plaques from subjects with and without subsequent adverse cardiovascular events. Multivariable analysis revealed carotid plaque Hounsfield unit density (
< .001) and spotty calcium (
< .001) as independent predictors of subsequent adverse cardiovascular events. In association with moderate carotid artery stenosis, the plaque Hounsfield unit values were significantly lower among carotid plaques from subjects who experienced subsequent adverse cardiovascular events (
= .002), strokes (
= .01), and cardiovascular deaths (
= .04); the presence of spotty calcium was significantly associated with the occurrence of adverse cardiovascular events (
= .001), acute coronary syndrome (
= .01), and cardiovascular death (
= .04).
Carotid plaque Hounsfield unit density and spotty calcium were independent predictors of a greater risk of adverse cardiovascular event occurrence.
This is the first report of significant energization (up to 7,000 eV) of low‐energy He+ ions, which occurred simultaneously with H‐band electromagnetic ion cyclotron (EMIC) wave activity, in a ...direction mostly perpendicular to the ambient magnetic field. The event was detected by the Arase satellite in the dayside plasmatrough region off the magnetic equator on 15 May 2019. The peak energy of the He+ flux enhancements is mostly above 1,000 eV. At some interval, the He+ ions are energized up to ∼7,000 eV. The H‐band waves are excited in a frequency band between the local crossover and helium gyrofrequencies and are close to a linear polarization state with weakly left‐handed or right‐handed polarization. The normal angle of the waves exhibits significant variation between 0° and 80°, indicating a non‐parallel propagation. We run a hybrid code with parameters estimated from the Arase observations to examine the He+ energization. The simulations show that cold He+ ions are energized up to more than 1,000 eV, similar to the spacecraft observations. From the analysis of the simulated wave fields and cold plasma motions, we found that the ratio of the wave frequency to He+ gyrofrequency is a primary factor for transverse energization of cold He+ ions. As a consequence of the numerical analysis, we suggest that the significant transverse energization of He+ ions observed by Arase is attributed to H‐band EMIC waves excited near the local helium gyrofrequency.
Key Points
Strong H‐band EMIC waves were detected in the dayside plasmatrough region off the magnetic equator by the Arase spacecraft
The H‐band waves energize cold He+ ions to levels above ∼1,000 eV in the direction perpendicular to the background magnetic field
Simulation indicates that the ratio of the wave frequency to He+ gyrofrequency is a primary factor in the strong energization of He+ ions