ACCESS Magazine, Fall 1994 Handy, Susan; Cervero, Robert; Landis, John D ...
IDEAS Working Paper Series from RePEc,
01/1994
Paper
Odprti dostop
In this issue of ACCESS, we examine how land use considerations can improve transportation planning. Transportation planners have traditionally sought to maximize mobility by supplying better roads ...and common carriers, thus making it easier to move around. Seldom have they sought to improve the characteristics of destinations. That's been the responsibility of city planners and land developers. But, say our authors, that separation of land use and transportation planning is no longer good enough.
Creationism/evolution LANDIS, WILLIAM L.; MILLER, ROBERT L.; WOOLWINE, CHARLES C. ...
The Science teacher (National Science Teachers Association),
10/1981, Letnik:
48, Številka:
7
Journal Article
The ObjectStore database system LAMB, C; LANDIS, G; ORENSTEIN, J ...
Communications of the ACM,
10/1991, Letnik:
34, Številka:
10
Magazine Article
ObjectStore is an object-oriented database management system (OODBMS) that provides a tightly integrated language interface to the traditional database management system (DBMS) features of persistent ...storage, transaction management, distributed data access, and associative queries. ObjectStore was designed for use in applications that perform complex manipulations on large databases of objects with intricate structure. Developers of these applications require high productivity through ease of use, expressive power, a reusable code base, and tight integration with the host environment. Even more important is the need for high performance. Speed cannot be sacrificed to obtain these benefits. The key to meeting these requirements is the virtual memory-mapping architecture. ObjectStore's collection, relationship, and query facilities provide support for conceptual modeling constructs, such as multivalued attributes, and many-to-many relationships can be translated directly into declarative ObjectStore constructs.
Because acne is androgen dependent, antiandrogen therapy might improve the condition. Inocoterone acetate (RU 882) is a nonsteroidal antiandrogen that binds to the androgen receptor and has ...antiandrogenic activity in animal models. To test its topical effect on acne, 126 male subjects with facial acne completed a 16-week, multi-center, double-blind study in which the twice-daily application of a 10% solution of inocoterone was compared with vehicle solution. Baseline and monthly examinations included acne lesion counts and general and endocrine laboratory tests.
Inflammatory papules and pustules showed greater reduction in the inocoterone-treated subjects than in the subjects treated with vehicle. This difference achieved statistical significance by week 12 (24% reduction vs 10%) and week 16 (26% reduction vs 13%) and, with longitudinal analysis, throughout the course of the study. Global assessments and changes in comedo counts and sebum excretion rates were not significantly different between the groups. No serious adverse reactions were encountered.
In this double-blind study of 126 male subjects with acne, a topical solution of the antiandrogen inocoterone, compared with vehicle, produced a modest but statistically significant reduction in the number of inflammatory acne lesions.
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