L’innocuité de deux vaccins commercialisés en France contre la babésiose canine – Nobivac Piro® (NP) et Pirodog® (P) – a été étudiée. Leur impact local, général et biochimique a été comparé, en ...conditions expérimentales maîtrisées, sur un groupe témoin (T) et deux groupes vaccinés deux fois à 21 jours d’intervalle. Tous les chiens ont présenté une réaction locale modérée. Cependant, le groupe NP a présenté une réaction locale significativement plus intense que le groupe P. Ceci est objectivé par les paramètres cliniques et biologiques. Aucune différence statistiquement significative n’est mise en évidence entre les évolutions des groupes P et T.
The safety of two vaccines available on the French market against canine babesiosis – Nobivac Piro® (NP) and Pirodog® (P) – have been evaluated. Their local, general and biochemical impacts have been compared in a controlled experimental study. Three groups were used: a control group (T) and two groups vaccinated twice at 21 days interval. All dogs presented moderate local reaction. However, either clinical and biological parameters showed that the NP group presented a significantly more intense reaction at the injection site compared to the P group. No statistical difference has been revealed between the groups P and T evolutions.
Efficacy of the Leptospira components of multivalent vaccine DAPPi-L was previously demonstrated against virulent challenge with three serovars of Leptospira interrogans (Canicola, ...Icterohaemorrhagiae and Grippotyphosa) carried out 14 days after primary vaccination.
In this study we demonstrate that this vaccine provides, two weeks after vaccination, an additional protection (prevention of mortality, clinical signs, renal infection, bacterial excretion, renal carriage and renal lesions) against fatal leptospirosis due to Leptospira interrogans serovar Copenhageni (serovar of major medical importance).
Résumé
L’après-cancer, phase de transition, représente pour le patient un réel travail psychique. Des difficultés, tant somatiques que psychiques, peuvent émerger très à distance de la survenue du ...cancer. Élaborées tout au long de la préparation du 29e congrès de la SFPO (Caen, octobre 2012), les recommandations de la SFPO ont pour objectif de mieux appréhender cette période et les difficultés associées, et de soutenir une évolution de l’organisation des soins psychooncologiques dans l’après-cancer, ainsi que leur intégration à la prise en charge globale et continue du patient. Cette intégration repose entre autres sur la qualité du maillage ville/hôpital (qualité des transmissions) et l’accessibilité au long cours des soins psychiques. Elle est garante de l’adaptation des soins psychiques à la réalité somatique comme de la prise en compte des facteurs émotionnels dans les symptômes physiques. Ces recommandations, ancrées sur une analyse de la littérature et l’expertise professionnelle collective, définissent: 1) l’importance de l’évaluation de l’état psychologique des patients et du contexte familial dans l’après-cancer par les équipes oncologiques hospitalières et les acteurs de soins de ville, y compris devant tout symptôme physique sévère; 2) la nécessité d’une évaluation spécialisée par un professionnel du soin psychique devant toute symptomatologie émotionnelle durable ou itérative, tout symptôme fonctionnel persistant, toute plainte cognitive ou toute difficulté de reprise des rôles familiaux et socioprofessionnels; 3) les modalités d’anticipation des difficultés de l’aprèscancer; 4) la nécessité d’accès aux soins psychiques dans le long terme; 5) la nécessité d’intégrer systématiquement dans le programme personnalisé de soins une consultation psychologique; 6) les perspectives de recherche.
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•ASAXS and electron tomography provide insight on aggregate structure and morphology.•Reduction has little effect on the cobalt particles size in Fischer-Tropsch catalysts.•Reduction ...has a significant effect on the Co aggregates morphology and structure.
Diversification of liquid fuel sources for transportation plays a key role in the energetic transition. High quality and clean diesels can be produced by Fischer-Tropsch synthesis, which interest is renewed in as much it can be performed from syngas (CO + H2) produced by conversion of natural gas or gasification of lignocellulosic biomass, leading, in this latter case, to fuels from renewable resource. Catalytic performance (activity and selectivity) of cobalt-based catalysts are related to the physico-chemical characteristics of the cobalt nanoparticles. The present study proposes a new approach to obtain a detailed and exhaustive description of the cobalt active phase in FT catalysts. We combined Anomalous Small X ray Scattering (ASAXS) and electron tomography, giving complementary insights on the microstructure and size distribution of both cobalt nanoparticles and aggregates. This approach, carried out on a cobalt/alumina-silica catalysts studied first at the oxide state and then at the reduced state, allowed to highlight the mechanisms involved at the nanoscale during the reduction step. Reduction impact is significant on aggregates morphology, causing their fragmentation and increasing their accessibility. As a perspective, a better knowledge of cobalt aggregates morphology will help to understand their impact on the catalyst performance.
Primary Spontaneous Pneumothorax (PSP) is usually considered as a benign pathology occurring in young people. In about half of cases, observation only is purposed. In case of intervention, chest tube ...drainage remains the preponderant strategy even if no studies conclude about superiority of drainage or aspiration. Re-expansion pulmonary edema (REPE) is a rare but potentially severe complication of chest tube drainage. Risk factors are not well identified, but REPE is more frequent for patients with diabetes, younger than 40 years, with large pneumothorax, lung collapse more than one week and fast re-expansion.
We report a case of a 19-year old male presenting to the Emergency Department with a first episode of PSP. He was treated by chest tube drainage with immediate suction. He developed a REPE 3 hours after chest tube drainage with suction. Conservative management and oxygen therapy led to withdrawing the chest tube 9 days later.
For the initial management of PSP, prevention of this complication is essential. In case of risk factors, prevention consist of absence of immediate suction after chest tube drainage and suction should be reserved in case of failure of initial treatment after 24 hours. Even if chest tube drainage is a common gesture, clinical presentation of REPE must alert physicians taking care of these patients.
Tubulocystic renal cell carcinoma (TC-RCC) is a recently identified renal malignancy. While approximately 100 cases of TC-RCC have been reported in the pathology literature, imaging features have not ...yet been clearly described. The purpose of this review is to describe the main radiologic features of this rare sub-type of RCC on ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective HIPAA-compliant review of pathology and imaging databases. Using a combination of sonographic and CT/MRI features, diagnosis of TC-RCC appeared to be strongly suggested in many cases.
Key Points
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Tubulocystic renal cell carcinoma is a new entity with typical imaging features
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Diagnosis of tubulocystic renal cell carcinoma can be suggested preoperatively by imaging
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Cystic renal lesions with high echogenicity may correspond to tubulocystic carcinoma
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