This paper investigates the essentially ‘Lacanian’ function of the cut in cinematic logic, arguing that the historical relationship between cinema and psychoanalysis is rooted in their shared logic ...of elision and division. However, while standard cinematic practice is to disavow the cut (through the repressive operation of ‘suture’) so as to construct and conserve the filmic ‘fantasy’ and thereby strengthen the imaginary, psychoanalysis contrarily seeks to directly attain to the real by traversing the fantasy along the lines of the cut. In examining this ‘diverging convergence’, the paper looks to the cinema of Alfred Hitchcock, whose celebrated films cut across both sides of the divide, providing the comfort of ‘imaginary resolution’ while at the same time undermining this equilibrium by directlyinvoking the real in the form and figure of the cut. In particular, the paper examines how Hitchcock’s films supplement the various cuts constitutive of cinema’s very beingwith an additional ‘foundational cut’; a cut that is equally formative of the film itself, but which simultaneously introduces a fundamentally determinativerift in this world, a central hole around which everything – plot, image, dialogue, etc. – twists and turns (and which is, moreover, intimately tied to Lacan’s formulation of the subject-object relation). The paper then goes on to address two key questions arising from this examination: what becomes of suture when cinema, like psychoanalysis, truly acknowledges the cut and traverses its own fantasy; and (following Žižek) is there really a ‘proper’ way to remake a (Hitchcock) film? Keywords: Suture; Fantasy; Real; Cinema; Hitchcock.
Purpose
Ultrasound compounding is to combine sonographic information captured from different angles and produce a single image. It is important for multi-view reconstruction, but as of yet there is ...no consensus on best practices for compounding. Current popular methods inevitably suppress or altogether leave out bright or dark regions that are useful and potentially introduce new artifacts. In this work, we establish a new algorithm to compound the overlapping pixels from different viewpoints in ultrasound.
Methods
Inspired by image fusion algorithms and ultrasound confidence, we uniquely leverage Laplacian and Gaussian pyramids to preserve the maximum boundary contrast without overemphasizing noise, speckles, and other artifacts in the compounded image, while taking the direction of the ultrasound probe into account. Besides, we designed an algorithm that detects the useful boundaries in ultrasound images to further improve the boundary contrast.
Results
We evaluate our algorithm by comparing it with previous algorithms both qualitatively and quantitatively, and we show that our approach not only preserves both light and dark details, but also somewhat suppresses noise and artifacts, rather than amplifying them. We also show that our algorithm can improve the performance of downstream tasks like segmentation.
Conclusion
Our proposed method that is based on confidence, contrast, and both Gaussian and Laplacian pyramids appears to be better at preserving contrast at anatomic boundaries while suppressing artifacts than any of the other approaches we tested. This algorithm may have future utility with downstream tasks such as 3D ultrasound volume reconstruction and segmentation.
Multi-parametric MRI (mpMRI) is widely used for prostate cancer (PCa) diagnosis. Deep learning models show good performance in detecting PCa on mpMRI, but domain-specific PCa-related anatomical ...information is sometimes overlooked and not fully explored even by state-of-the-art deep learning models, causing potential suboptimal performances in PCa detection. Symmetric-related anatomical information is commonly used when distinguishing PCa lesions from other visually similar but benign prostate tissue. In addition, different combinations of mpMRI findings are used for evaluating the aggressiveness of PCa for abnormal findings allocated in different prostate zones. In this study, we investigate these domain-specific anatomical properties in PCa diagnosis and how we can adopt them into the deep learning framework to improve the model's detection performance. We propose an anatomical-aware PCa detection Network (AtPCa-Net) for PCa detection on mpMRI. Experiments show that the AtPCa-Net can better utilize the anatomical-related information, and the proposed anatomical-aware designs help improve the overall model performance on both PCa detection and patient-level classification.
We demonstrate and characterize interference between discrete photons emitted by two separate semiconductor quantum dot states in different samples excited by a pulsed laser. Their energies are tuned ...into resonance using strain. The photons have a total coalescence probability of 18.1% and the coincidence rate is below the classical limit. Postselection of coincidences within a narrow time window increases the coalescence probability to 47%. The probabilities are reduced from unity because of dephasing and the postselection value is also reduced by the detector time response.
This book offers an in-depth examination of cinema and its philosophical significance. Alex Ling employs the philosophy of Alain Badiou to answer the question central to all serious film scholarship ...- namely, 'can cinema be thought?' - using films ranging from Hiroshima mon amour to Vertigo to The Matrix to illustrate Badiou's philosophy.
Quantum communication is a prime space technology application and offers near-term possibilities for long-distance quantum key distribution (QKD) and experimental tests of quantum entanglement. ...However, there exists considerable developmental risks and subsequent costs and time required to raise the technological readiness level of terrestrial quantum technologies and to adapt them for space operations. The small-space revolution is a promising route by which synergistic advances in miniaturization of both satellite systems and quantum technologies can be combined to leap-frog conventional space systems development. Here, we outline a recent proposal to perform orbit-to-ground transmission of entanglement and QKD using a CubeSat platform deployed from the International Space Station (ISS). This ambitious mission exploits advances in nanosatellite attitude determination and control systems (ADCS), miniaturised target acquisition and tracking sensors, compact and robust sources of single and entangled photons, and high-speed classical communications systems, all to be incorporated within a 10 kg 6 litre mass-volume envelope. The CubeSat Quantum Communications Mission (CQuCoM) would be a pathfinder for advanced nanosatellite payloads and operations, and would establish the basis for a constellation of low-Earth orbit trusted-nodes for QKD service provision.
Objective and Impact Statement.
We propose a weakly- and semisupervised, probabilistic needle-and-reverberation-artifact segmentation algorithm to separate the desired tissue-based pixel values from ...the superimposed artifacts. Our method models the intensity decay of artifact intensities and is designed to minimize the human labeling error.
Introduction.
Ultrasound image quality has continually been improving. However, when needles or other metallic objects are operating inside the tissue, the resulting reverberation artifacts can severely corrupt the surrounding image quality. Such effects are challenging for existing computer vision algorithms for medical image analysis. Needle reverberation artifacts can be hard to identify at times and affect various pixel values to different degrees. The boundaries of such artifacts are ambiguous, leading to disagreement among human experts labeling the artifacts.
Methods.
Our learning-based framework consists of three parts. The first part is a probabilistic segmentation network to generate the soft labels based on the human labels. These soft labels are input into the second part which is the transform function, where the training labels for the third part are generated. The third part outputs the final masks which quantifies the reverberation artifacts.
Results.
We demonstrate the applicability of the approach and compare it against other segmentation algorithms. Our method is capable of both differentiating between the reverberations from artifact-free patches and modeling the intensity fall-off in the artifacts.
Conclusion.
Our method matches state-of-the-art artifact segmentation performance and sets a new standard in estimating the per-pixel contributions of artifact vs underlying anatomy, especially in the immediately adjacent regions between reverberation lines. Our algorithm is also able to improve the performance of downstream image analysis algorithms.
He has been regarded with suspicion by some, as an anti-postmodernist who dared to write about unfashionable concepts such as truth and meaning. But in recent years, the philosopher Alain Badiou has ...risen in prominence, pioneering new ways to produce, conceptualise and discover art. Badiou Reframed is an original book about an original thinker which applies - for the first time - Badiou's philosophy to the visual arts. The six central concepts of this philosophy - 'being and appearing', 'event and subject' and 'truth and ethics' - are elucidated through detailed analysis of a range of visual artworks, including Marcel Duchamp's readymades, the abstract paintings of Kazimir Malevich and Mark Rothko, Banksy's contemporary street art, the sculpture of Alberto Giacometti, Stephane Mallarme's visual poetry and Victor Fleming's classic film The Wizard of Oz. In focusing on Badiou's critical relationship with the visual arts, Alex Ling reinterprets and represents not only the man, but art itself.
Familial aggregations of testicular germ cell tumor (FTGCT) have been well described, suggesting the existence of a hereditary TGCT subset. Approximately 1.4% of newly diagnosed TGCT patients report ...a positive family history of TGCT. Sons and siblings of TGCT patients have four- to sixfold and eight- to tenfold increases in TGCT risk respectively. Segregation analyses suggest an autosomal recessive mode of inheritance. Linkage analyses have identified several genomic regions of modest interest, although no high-penetrance cancer susceptibility gene has been mapped yet. These data suggest that the combined effects of multiple common alleles, each conferring modest risk, might underlie familial testicular cancer. Families display a mild phenotype: the most common number of affected families is 2. Age at diagnosis is 2-3 years younger for familial versus sporadic cases. The ratio of familial seminoma to nonseminoma is 1.0. FTGCT is more likely to be bilateral than sporadic TGCT. This syndrome is cancer site specific. Testicular microlithiasis is a newly recognized FTGCT component. Candidate gene-association studies have implicated the Y chromosome gr/gr deletion and PDE11A gene mutations as genetic modifiers of FTGCT risk. Two genomewide association studies of predominantly sporadic but also familial cases of TGCT have implicated the KIT-ligand, SPRY4, and BAK1 genes as TGCT risk modifiers. All five loci are involved in normal testicular development and/or male infertility. These genetic data provide a novel insight into the genetic basis of FTGCT, and an invaluable guide to future TGCT research.
Renal function and imaging findings have not been comprehensively and prospectively characterized in a broad age range of patients with molecularly confirmed autosomal recessive polycystic kidney ...disease (ARPKD).
Ninety potential ARPKD patients were examined at the National Institutes of Health Clinical Center. Seventy-three fulfilled clinical diagnostic criteria, had at least one PKHD1 mutation, and were prospectively evaluated using magnetic resonance imaging (MRI), high-resolution ultrasonography (HR-USG), and measures of glomerular and tubular function.
Among 31 perinatally symptomatic patients, 25% required renal replacement therapy by age 11 years; among 42 patients who became symptomatic beyond 1 month (nonperinatal), 25% required kidney transplantation by age 32 years. Creatinine clearance (CrCl) for nonperinatal patients (103 +/- 54 ml/min/1.73 m(2)) was greater than for perinatal patients (62 +/- 33) (P = 0.002). Corticomedullary involvement on HR-USG was associated with a significantly worse mean CrCl (61 +/- 32) in comparison with medullary involvement only (131 +/- 46) (P < 0.0001). Among children with enlarged kidneys, volume correlated inversely with function, although with wide variability. Severity of PKHD1 mutations did not determine kidney size or function. In 35% of patients with medullary-only abnormalities, standard ultrasound was normal and the pathology was detectable with HR-USG.
In ARPKD, perinatal presentation and corticomedullary involvement are associated with faster progression of kidney disease. Mild ARPKD is best detected by HR-USG. Considerable variability occurs that is not explained by the type of PKHD1 mutation.
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