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In this contribution we present a novel technique, called projective reference evaluation (PRE), for a reliable determination of concentrations from signals of flow injection analysis. Using this ...technique the whole measurement signal is employed for the evaluation procedure by projecting it to a reference measurement signal. Exploiting this projection, the evaluation technique uses inherently all the information about the specific analysis system under consideration. To test the PRE technique, we applied it to severely distorted measurements as well as measurements of a double injection system for the determination of sucrose in the presence of glucose. The results of this evaluation technique are compared to results obtained by partial least squares analysis. The potential of the new technique especially for the evaluation of faulty measurement signals is discussed.