A new compressive sensing (CS) scheme using the structured random matrix and the discrete periodic Radon transform (DPRT) is proposed. The new scheme first pre-randomises the sensing image and the ...DPRT is applied to the randomised samples to generate the so-called DPRT projections. They are then randomly selected to obtain the final sensing measurements. As the DPRT is friendly to hardware/optics implementation, it improves the operability and lowers the cost for real-time CS applications. Compared with other similar transforms such as the Walsh–Hadamard transform, the proposed DPRT scheme gives much better reconstructed images as shown in the simulation results.
Previous studies suggest that flood-rich and flood-poor periods are present in many flood peak discharge series around the globe. Understanding the occurrence of these periods and their driving ...mechanisms is important for reliably estimating future flood probabilities. We propose a method for detecting flood-rich and flood-poor periods in peak-over-threshold series based on scan-statistics and combine it with a flood typology in order to attribute the periods to their flood-generating mechanisms. The method is applied to 164 observed flood series in southern Germany from 1930 to 2018. The results reveal significant flood-rich periods of heavy-rainfall floods, especially in the Danube river basin in the most recent decades. These are consistent with trend analyses from the literature. Additionally, significant flood-poor periods of snowmelt-floods in the immediate past were detected, especially for low-elevation catchments in the alpine foreland and the uplands. The occurrence of flood-rich and flood-poor periods is interpreted in terms of increases in the frequency of heavy rainfall in the alpine foreland and decreases of both soil moisture and snow cover in the midlands.
Abstract Aims Surgical treatment of periacetabular tumors remains one of the most challenging problems in musculoskeletal oncology. The purpose of this study was to review the clinical and functional ...outcomes of resection hip arthroplasty and analyze its feasibility. Methods This study assesses twenty-seven patients with periacetabular tumors treated by resection hip arthroplasty between 1999 and 2010. The tumors were excised with wide margins and the residual intact femoral head placed underneath the resected ilium. Clinical, functional and oncological outcomes as well as complications were carefully evaluated. Results The average follow-up time was 55 months (range, 3–118) and the mean surgical time 170 min (range, 120–350) with an average blood loss 1200 ml (range, 600–2200). Six patients died in 6–33 months postoperatively; no other local recurrences or deaths occurred. The 1-year, 5-year, and 10-year disease-free survival rates were 96.3%, 77.8% and 77.8% respectively. The mean limb-length discrepancy was 5 cm (range, 2–7.5) and all patients required custom-made shoes with their heels heightened by 2–5 cm. At the last follow-up, the mean functional score was 75.6%. Twenty patients recovered normal ambulation function with custom-made shoes and seven had to walk with crutches. Wound healing problems were observed in nine patients and deep or superficial infection in none. Conclusions Resection hip arthroplasty is recommended as a feasible surgical protocol for periacetabular tumors because it has few complications, good functional results, short surgical time and little blood loss.
Abstract
In order to improve the identification efficiency and accuracy of distribution network ground fault identification methods, this paper proposes a distribution network ground fault ...identification method based on MMC injection detection signal strategy. Extract the fault information of distribution network grounding line, calculate the current component of three-phase current, and obtain the grounding fault data of distribution network.The detection current of distribution network is obtained by injection signal detection strategy. The fault information matrix is formed by using the detection current information, and the time-frequency characteristics of MMC injection detection signal strategy are obtained according to the actual situation.The wavelet transform is used to remove the clutter in the fault feature vector, and the normalized processing is used to obtain and process the ground fault vector.According to the wavelet function, the characteristics of the distribution network ground fault signal are determined. Cassie model and Mayr model are used to obtain the final distribution network ground fault identification model to realize the distribution network ground fault identification.The experimental results show that the accuracy of the method can reach 96.1%, and the time of fault identification is only 25s. The above results show that the method can effectively improve the effectiveness of distribution network ground fault identification.
Thalidomide pharmacokinetics in sheep Smith, SL; Singh, P; Harding, D ...
New Zealand veterinary journal,
07/2016, Letnik:
64, Številka:
4
Journal Article
Recenzirano
AIM: To determine the half life (T
1/2
), time taken to reach maximum plasma concentration (T
max
) and maximum plasma concentration (C
max
) of thalidomide in sheep following I/V, oral and topical ...treatment with a single dose of thalidomide.
METHOD: Three groups of 4-6-month-old ram lambs were treated with thalidomide dissolved in dimethylsulphoxide (DMSO). The first group (n=10) was treated I/V with 100 mg thalidomide in 2 mL DMSO; the second group (n=8) received 400 mg thalidomide in 2 mL DMSO orally, and the third group (n=8) had 400 mg thalidomide in 4 mL DMSO applied topically. Plasma samples were collected up to 36 hours after treatment, snap-frozen at −80°C and analysed for concentrations of thalidomide using high performance liquid chromatography.
RESULTS: Following I/V administration, T
1/2
was 5.0 (SEM 0.4) hours, volume of distribution was 3,372.0 (SEM 244.3) mL/kg and clearance was 487.1 (SEM 46.1) mL/hour.kg. Topical application of 400 mg thalidomide did not increase plasma concentrations. Following oral administration, thalidomide bioavailability was 89%, with T
1/2
, T
max
, and C
max
being 7.2 (SEM 0.8) hours, 3.0 (SEM 0.4) hours and 1,767.3 (SEM 178.1) ng/mL, respectively.
CONCLUSION: Topical administration using DMSO as a solvent did not increase concentrations of thalidomide in plasma. The mean pharmacokinetic parameters determined following oral treatment with 400 mg of thalidomide were similar to those reported in humans receiving a single 400 mg oral dose (T
1/2
7.3 hours; T
max
4.3 hours and C
max
2,820 ng/mL). There is potential for thalidomide to be used as a model for the treatment of chronic inflammatory conditions in sheep, such as Johne's disease, where tumour necrosis factor alpha plays a pathogenic role.
A novel vector quantisation codebook initialisation method called vector component difference is proposed for image coding using the discrete multiwavelet transform. Simulation results show that it ...is superior to the currently available methods when using with the Linde-Buzo-Gray codebook generation algorithm.
Recent studies have revealed evidence of trends in the median or mean flood discharge in Europe over the last 5 decades, with clear and coherent
regional patterns. The aim of this study is to assess ...whether trends in flood discharges also occurred for larger return periods, accounting for
the effect of catchment scale. We analyse 2370 flood discharge records, selected from a newly available pan-European flood database, with record
length of at least 40 years over the period 1960–2010 and with contributing catchment area ranging from 5 to 100 000 km2. To estimate
regional flood trends, we use a non-stationary regional flood frequency approach consisting of a regional Gumbel distribution, whose median and
growth factor can vary in time with different strengths for different catchment sizes. A Bayesian Markov chain Monte Carlo (MCMC) approach is used
for parameter estimation. We quantify regional trends (and the related sample uncertainties), for floods of selected return periods and for
selected catchment areas, across Europe and for three regions where coherent flood trends have been identified in previous studies. Results show
that in northwestern Europe the trends in flood magnitude are generally positive. In small catchments (up to 100 km2), the 100-year flood
increases more than the median flood, while the opposite is observed in medium and large catchments, where even some negative trends appear,
especially in northwestern France. In southern Europe flood trends are generally negative. The 100-year flood decreases less than the median flood,
and, in the small catchments, the median flood decreases less compared to the large catchments. In eastern Europe the regional trends are negative
and do not depend on the return period, but catchment area plays a substantial role: the larger the catchment, the more negative the trend.
Recent studies have shown evidence of increasing and decreasing trends for average floods and flood quantiles across Europe. Studies attributing observed changes in flood peaks to their drivers have ...mostly focused on the average flood behaviour, without distinguishing small and large floods. This paper proposes a new framework for attributing flood changes to potential drivers, as a function of return period (T), in a regional context. We assume flood peaks to follow a non-stationary regional Gumbel distribution, where the median flood and the 100-year growth factor are used as parameters. They are allowed to vary in time and between catchments as a function of the drivers quantified by covariates. The elasticities of floods with respect to the drivers and the contributions of the drivers to flood changes are estimated by Bayesian inference. The prior distributions of the elasticities of flood quantiles to the drivers are estimated by hydrological reasoning and from the literature.
The attribution model is applied to European flood and covariate data and aims at attributing the observed flood trend patterns to specific drivers for different return periods at the regional scale. We analyse flood discharge records from 2370 hydrometric stations in Europe over the period 1960–2010. Extreme precipitation, antecedent soil moisture and snowmelt are the potential drivers of flood change considered in this study. Results show that, in northwestern Europe, extreme precipitation mainly contributes to changes in both the median (q2) and 100-year flood (q100), while the contributions of antecedent soil moisture are of secondary importance. In southern Europe, both antecedent soil moisture and extreme precipitation contribute to flood changes, and their relative importance depends on the return period. Antecedent soil moisture is the main contributor to changes in q2, while the contributions of the two drivers to changes in larger floods (T>10 years) are comparable. In eastern Europe, snowmelt drives changes in both q2 and q100.
To observe the efficacy of the circumferential decompression with posterior transpedicular osteotomy and segmental instrumentation with interbody fusion for thoracic ossification of posterior ...Iongitudinal ligament (T-OPLL).
From May 2012 to June 2015, 16 consecutive patients underwent posterior transpedicular osteotomy and segmental instrumentation with interbody fusion.Osteotomy range was depended by length and types of OPLL.Patient's data included level, clinical presentation, blood loss, length of surgery, complications, VAS, JOA, and Frankel grading system before and after the surgery. All data were collected, retrospectively.
The follow-up period was (30±19) months (range from 12 to 50 months). The operation time was (261.6±51.3) min (range from 190 to 310 min). The blood loss was (980.3±370.5) ml (range from 600 to 2 100 ml). All patients were well treated with posterior compression and segmental instrumentation with interbody fusion.The VAS score was (4.2±0.2) in all patients at a week, improving to (2
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