Plasma and/or urine cyclic adenosine 3′,5′‐monophosphate (cAMP) and cyclic guanosine 3′,5′‐mono‐phosphate (cGMP) levels were measured in 67 normal subjects, 55 patients with nonneoplastic diseases, ...and 324 patients with ten different types of cancer. There were no significant differences in plasma and urine cyclic nucleotide levels between normal subjects and patients with non‐neoplastic diseases. In untreated cancer patients, plasma and urine cAMP levels were similar to those of normal subjects, whereas plasma and urine cGMP levels were markedly higher. This pattern was common to all the cancer groups studied. Chemotherapy per se did not seem to influence cyclic nucleotide levels in cancer patients. However, plasma and urine cGMP levels normalized in all patients who attained complete remission. Moreover, in acute leukemia patients who relapsed, plasma cGMP levels increased significantly with respect to the complete remission values, thus suggesting that this parameter may be useful in monitoring the response of cancer patients to treatment.
Prolymphocytic leukemia (PL) is a morphologically distinct disease generally characterized by unsatisfactory therapeutic response and brief survival. Aggressive chemotherapy protocols including ...doxorubicin (DX) have been successfully used as alternatives to treatments usually effective in chronic lymphocytic leukemia (CLL). A patient with typical PL, resistant to regimens containing DX, was treated with 4‐demethoxydaunorubicin (4‐dm DNR), a new anthracycline analog derived from daunorubicin (DNR). The therapeutic response was rapid and impressive; furthermore 4‐dm DNR combined with arabinosyl cytosine (Ara‐C) produced a complete remission which is unusual in PL.
Terminal deoxynucleotidyl transferase, TdT, was assayed in the mononucleate cells of blood and bone marrow from 121 patients with leukemias at the onset of disease and from 95 subjects with malignant ...lymphomas at diagnosis. This intracellular marker was also investigated by cytoimmunofluorescent tests in 17 other cases of initial leukemias and in 3 diagnosed lymphoblastic lymphomas. Generally, the TdT levels were significantly enhanced in the blasts of the following: acute undifferentiated leukemias; the more immature types of acute lymphoblastic leukemias i.e., the null, non-T non-B, common, early T and pre-B subgroups; a fraction of blastic crises in chronic myelogenous leukemias; and many lymphoblastic lymphomas. TdT might also be slightly increased in the mononucleate blood cells obtained from the most immature forms of acute myelogenous leukemias. Relapses with changes in cell phenotypes were occasionally observed in previously TdT-positive leukemias as a result of clonal evolution of the disease. The leukemias with blasts containing high levels of TdT were usually responsive to treatment with corticosteroids and vincristine. TdT is an oligoclonal marker characterizing several populations of undifferentiated or poorly differentiated blasts that tend to develop towards or along the lymphoid pathway. Together with specific immunological markers, this enzyme is useful to define the particular type of leukemic cells. It also serves to identify the quasi-lymphoblastic nature of the malignant clone, a helpful indication for the choice of therapy.
Astrophys.J.655:316-331,2007 We present the 12CO(1-0) and 13CO(2-1) line maps obtained observing with the
SEST a $\sim 1\degr \times 1\degr$ region of the Vela Molecular Ridge, Cloud D.
This cloud is ...part of an intermediate-mass star forming region that is
relatively close to the Sun. Our observations reveal, over a wide range of
spatial scales (from $\sim 0.1$ to a few parsecs), a variety of dense
structures such as arcs, filaments and clumps, that are in many cases
associated with far-IR point-like sources, recognized as young stellar objects
and embedded star clusters. The velocity field analysis highlights the presence
of possible expanding shells, extending over several parsecs, probably related
to the star forming activity of the cloud. Furthermore, the analysis of the
line shapes in the vicinity of the far-IR sources allowed the detection of 13
molecular outflows. Considering a hierarchical scenario for the gas structure,
a cloud decomposition was obtained for both spectral lines by means of the
CLUMPFIND algorithm. The CLUMPFIND output has been discussed critically and a
method is proposed to reasonably correct the list of the identified clumps. We
find that the corresponding mass spectrum shows a spectral index $\alpha\sim1.3
\div 2.0$ and the derived clump masses are below the corresponding virial
masses. The mass-radius and velocity dispersion-radius relationships are also
briefly discussed for the recovered clump population.
We present the 12CO(1-0) and 13CO(2-1) line maps obtained observing with the SEST a \(\sim 1\degr \times 1\degr\) region of the Vela Molecular Ridge, Cloud D. This cloud is part of an ...intermediate-mass star forming region that is relatively close to the Sun. Our observations reveal, over a wide range of spatial scales (from \(\sim 0.1\) to a few parsecs), a variety of dense structures such as arcs, filaments and clumps, that are in many cases associated with far-IR point-like sources, recognized as young stellar objects and embedded star clusters. The velocity field analysis highlights the presence of possible expanding shells, extending over several parsecs, probably related to the star forming activity of the cloud. Furthermore, the analysis of the line shapes in the vicinity of the far-IR sources allowed the detection of 13 molecular outflows. Considering a hierarchical scenario for the gas structure, a cloud decomposition was obtained for both spectral lines by means of the CLUMPFIND algorithm. The CLUMPFIND output has been discussed critically and a method is proposed to reasonably correct the list of the identified clumps. We find that the corresponding mass spectrum shows a spectral index \(\alpha\sim1.3 \div 2.0\) and the derived clump masses are below the corresponding virial masses. The mass-radius and velocity dispersion-radius relationships are also briefly discussed for the recovered clump population.
Reviews of Books LeDonne, John P.; Gerberding, Richard A.; Morris, Richard ...
The International History Review,
20/6/1/, Letnik:
27, Številka:
2
Book Review
Recenzirano
CHARLES KING. The Black Sea: A History. New York: Oxford University Press, 2004. Pp. xx, 276. $60.00 (CDN). Reviewed By John P. Ledonne
ANDREW GILLETT. Envoys and Political Communication in the Late ...Antique West, 411-533. New York: Cambridge University Press, 2003. Pp. xvii, 335. $65.00 (US). Reviewed by Richard A. Gerberding
TIM PESTELL and KATHARINA ULMSCHNEIDER, eds. Markets in Early Medieval Europe: Trading and 'Productive' Sites, 650-850. Macclesfield: Windgather Press, 2003. Pp. xvi, 304. £25.00. Reviewed by Richard Morris
KENNETH CHASE. Firearms: A Global History to 1700. New York: Cambridge University Press, 2003. Pp. xvii, 290. $30.00 (US). Reviewed by Bert S. Hall
OLIVIA REMIE CONSTABLE. Housing the Stranger in the Mediterranean World: Lodging, Trade, and Travel in Late Antiquity and the Middle Ages. New York: Cambridge University Press, 2003. Pp. xii, 427. $65.00 (US). Reviewed by Molly Greene
PAUL STEPHENSON. The Legend of Basil the Bulgar-Slayer. New York: Cambridge University Press, 2003. Pp. xvii, 164. $40.00 (US). Reviewed by Walter E. Kaegi
MARCUS BULL and NORMAN HOUSLEY, eds. The Experience of Crusading: I: Western Approaches. New York: Cambridge University Press, 2003. Pp. xvi, 307. $60.00 (US); PETER EDBURY and JONATHAN PHILLIPS, eds. The Experience of Crusading: II: Defining the Crusader Kingdom. New York: Cambridge University Press, 2003. Pp. xv, 311. $65.00 (US). Reviewed by Christopher Tyerman
MICHAEL ANGOLD. The Fourth Crusade: Event and Context. Harlow and New York: Pearson Longman, 2003. Pp. xxii, 281. $24.00 (US), paper. Reviewed by Jonathan Shepard
ROBERT BARTLETT. The Hanged Man: A Story of Miracle, Memory, and Colonialism in the Middle Ages. Princeton and Oxford: Princeton University Press, 2004. Pp. xi, 168. $24.95 (US). Reviewed by Michael D. Barber
ANDRE WINK. Al-Hind: The Making of the Indo-Islamic World: III: Indo-islamic Society, 14th$5th Centuries. Leiden: Brill, 2004. Pp. x, 282. €93.00. Reviewed by Sanjay Subrahmanyam
GEORGE E. BROOKS. Eurafricans in Western Africa: Commerce, Social Status, Gender, and Religious Observance from the Sixteenth to the Eighteenth Century. Athens: Ohio University Press; Oxford: James Currey, 2003. Pp. xxiii, 355. $26.95 (US). Reviewed by Allen M. Howard
FELIPE FERNÁNDEZ-ARMESTO. The Americas: The History of a Hemisphere. London: Weidenfeld and Nicolson, 2003. Pp. 199. £12.99. Reviewed by Lester D. Langley
WILLIAM B. COHEN. The French Encounter with Africans: White Response to Blacks, 1530-1880. Bloomington and Indianapolis: Indiana University Press, 2003. Pp. xxv, 360. $24.95 (US) paper. Reviewed by Martin Klein
JOSÉ C. CURTO. Enslaving Spirits: The Portuguese-Brazilian Alcohol Trade at Luanda and Its Hinterland c. 1550-1830. Leiden: Brill, 2004. Pp. xiv, 252. €74.00. Reviewed by A.J.R. RUSSELL-WOOD
EBERHARD SCHMITT and THOMAS BECK, eds. Das Leben in den Kolonien. Wiesbaden: Harrassowitz Verlag, 2003. Pp. xv, 546. €68.00. Reviewed by Hermann Wellenreuther
T. M. DEVINE. Scotland's Empire, 1600-1815. London: Allen Lane, Penguin Books, 2003. Pp. xxviii, 473. $50.00 (CDN). Reviewed By Bruce P. Lenman
GLYN REDWORTH. The Prince and the Infanta: The Cultural Politics of the Spanish Match. New Haven and London: Yale University Press, 2003. Pp. xiv, 200. $32.50 (US). Reviewed by Mark A. Kishlansky
W.J. ECCLES. Frontenac: The Courtier Governor. Lincoln and London: University of Nebraska Press, 2003, intro. Peter Moogk. Pp. xv,4o6. $24.95 (US), paper. Reviewed by Luca Codignola
DEREK BEALES. Prosperity and Plunder: European Catholic Monasteries in the Age of Revolution, 1650-1815. New York: Cambridge University Press, 2003. Pp. xviii, 395. $50.00 (US). Reviewed by Franz A.J. Szabo
JAMES CRACRAFT. The Revolution of Peter the Great. Cambridge, MA and London: Harvard University Press, 2003. Pp. ix, 192. $25.95 (US). Reviewed by Lindsey Hughes
JULIAN GWYN. Frigates and Foremasts: The North American Squadron in Nova Scotia Waters, 1745-1815. Vancouver: University of British Columbia Press, 2003. Pp. xiv, 206. $27.95 (CDN), paper. Reviewed by Paul Webb
HAROLD MAH. Enlightenment Phantasies: Cultural Identity in France and Germany, 1750-1914. Ithaca and London: Cornell University Press, 2003. Pp. x, 227. $39.95 (US). Reviewed by Margaret C.Jacob
ANTHONY J. HALL. The Bowl with One Spoon: I: The American Empire and the Fourth World. Montreal and Kingston: McGill-Queen's University Press, 2003. Pp. xlv, 683. $49.95 (CDN). Reviewed By Robin Ridington
DAVID C. HENDRICKSON. Peace Pact: The Lost World of the American Founding. Lawrence: University Press of Kansas, 2003. Pp. xiv, 402. $29.95 (US). Reviewed by ELIGA H. GOULD
LAURENT DUBOIS. A Colony of Citizens: Revolution and Slave Emancipation in the French Caribbean, 1787-1804. Chapel Hill and London: University of North Carolina Press, 2004, for the Omohundro Institute of Early American History and Culture, Williamsburg; dist. Toronto: SBS. Pp. x, 452. $37.25 (CDN), paper. Reviewed by William S. Cormack
PRADEEP P. BARUA. Gentlemen of the Raj: The Indian Army Officer Corps, 1817-1949. Westport: Praeger, 2003. Pp. xv, 180. $69.95 (US). Reviewed by Raymond A. Callahan
WILLIAM R. SUMMERHILL. Order against Progress: Government, Foreign Investment, and Railroads in Brazil, 1854-1913. Stanford: Stanford University Press, 2003. Pp. xv, 297. $60.00 (US). Reviewed by Todd A. Diacon
JAMES L. HEVIA. English Lessons: The Pedagogy of Imperialism in Nineteenth-Century China. Durham, NC and London: Duke University Press; Hong Kong: Hong Kong University Press, 2003. Pp. xviii, 387. $23.95 (US), paper. Reviewed by John E. Wills, Jr.
JAMES P. FLINT, OSB. Great Britain and the Holy See: The Diplomatic Relations Question, 1846-1852. Washington, DC: Catholic University of America Press, 2003; dist. Toronto: Scholarly Book Services. Pp. xvii, 301. $65.95 (CDN). Reviewed By Alan J. Reinerman
ROBERT J. BLYTH. The Empire of the Raj: India, Eastern Africa, and the Middle East, 1858-1947. Basingstoke and New York: Palgrave Macmillan, 2003. Pp. x, 270. $72.00 (US). Reviewed by John Darwin
GALEN ROGER PERRAS. Stepping Stones to Nowhere: The Aleutian Islands, Alaska, and American Military Strategy, 1867-1945. Vancouver: University of British Columbia Press, 2003. Pp. xiv, 274. $85.00 (CDN), cloth; $25.95 (CDN), paper. Reviewed by Terrence M. Cole
NEVILLE KIRK. Comrades and Cousins: Globalization, Workers, and Labour Movements in Britain, the USA, and Australia from the 1880s to 1914. London: Merlin Press, 2003; dist. Marshfield, MA: Paul & Co. Pp. x, 230. $29.95 (US), paper. Reviewed by William Kenefick
JOHN E. VAN SANT, ed., annotated, and intro. Mori Arinori's 'Life and Resources in America'. Lanham: Lexington Books, 2004. Pp. xli, 163. $24.95 (US), paper. Reviewed by F. G. Notehelfer
PETER WINZEN. Reichskanzler Bernhard Fürst von Bülow: Weltmachtstratege ohne Fortune - Wegbereiter der groβen Katastrophe. Göttingen and Zurich: Muster-Schmidt Verlag, 2003. Pp. 185. €14.00, paper. Reviewed by Kenneth W. Rock
IOANNA LALIOTOU. Transatlantic Subjects: Acts of Migration and Cultures of Transnationalism between Greece and America. Chicago and London: University of Chicago Press, 2004. Pp. xi, 257. $21.00 (US), paper. Reviewed by James R. Barrett
JORMA AHVENAINEN. The European Cable Companies in South America before the First World War. Helsinki: Finnish Academy of Science and Letters, 2004; dist. Helsinki: Bookstore Tiedkirja. Pp. 427. €35.00, paper. Reviewed by Daniel R. Headrick
CHRISTIAN RÖDEL. Krieger, Denker, Amateure: Alfred von Tirpitz und das Seekriegsbild vor dem Ersten Weltkrieg. Stuttgart: Franz Steiner Verlag, 2003. Pp. x, 234. €48.00, paper. Reviewed by Mark D. Karau
LILIANA SAIU. Stati Uniti e Italia nella Grande Guerra, 1914-1918. Florence: Leo S. Olschki, 2003. Pp. xiv, 255. €27.00, paper. Reviewed by Geoff Haywood
ROBIN HIGHAM. 100 Tears of Air Power and Aviation. College Station: Texas A & M University Press, 2003. Pp. xi, 435. $50.00 (US). Reviewed by Conrad C. Crane
KEN'ICHI GOTO. Tensions of Empire: Japan and Southeast Asia in the Colonial and Postcolonial World, ed. with intro. Paul H. Kratoska. Athens: Ohio University Press; Singapore: Singapore University Press, 2003. Pp. xxiv, 349. $17.95 (US), paper. Reviewed by Peter Duus
MAE M. NGAI. Impossible Subjects: Illegal Aliens and the Making of Modern America. Princeton and Oxford: Princeton University Press, 2004. Pp. xx, 377. $35.00 (US). Reviewed by David M. Reimers
GAWDAT BAHGAT. American Oil Diplomacy in the Persian Gulf and the Caspian Sea. Gainesville: University Press of Florida, 2003. Pp. xvi, 213. $39.95 (US); SHAFI ALDAMER. Saudi Arabia and Britain: Changing Relations, 1939-1953. Reading: Ithaca Press, 2003; dist. Portland: ISBS. Pp. ix, 277. $49.50 (US). Reviewed by Frederick F. Anscombe
JOAN BEAUMONT, CHRISTOPHER WATERS, DAVID LOWE, with GARRY WOODARD. Ministers, Mandarins, and Diplomats: Australian Foreign Policy Making, 1941-1969. Melbourne: Melbourne University Publishing, 2003; dist. Chicago: Paul & Company. Pp. xi, 223. $39.95 (AUS), paper; PETER EDWARDS and DAVID GOLDSWORTHY, eds. Facing North: A Century of Australian Engagement with Asia: II: 1970s to 2000. Melbourne: Melbourne University Press, 2003; dist. Chicago: Paul & Company. Pp. xxii, 467. $52.95 (US). Reviewed by David Mclean
JAMES P. LEVY. The Royal Navy's Home Fleet in World War II. New York: Palgrave Macmillan, 2003. Pp. xvii, 222. $65.00 (US). Reviewed by Christopher M. Bell
MARC MILNER. Battle of the Atlantic. St Catharines: Vanwell Publishing, 2003. Pp. 255. $39.95 (CDN). Reviewed By Joseph A. Maiolo
K. H. ADLER. Jews and Gender in Liberation France. New York: Cambridge University Press, 2003. Pp. xii, 273. $60.00 (US). Reviewed by Alice L. Conklin
SIMON C. SMITH. Britain's Revival and Fall in the Gulf: Kuwait, Bahrain, Qatar, and the Trucial States, 1950-71. London and New York: RoudedgeCurzon, 2004. Pp. vii, 210. $95.00 (US). Reviewed by Tore Tingvold Petersen
ALAN MCPHERSON. Yankee No! Anti-Ame
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