A 22;22 Robertsonian translocation was diagnosed in a husband whose wife had had six consecutive early spontaneous abortions and no normal progeny. With the new multiple-exposure photography (MEP) ...technique, an accurate, objective and documentary sperm analysis was performed. No abnormality of the essentially defective, genetically unbalanced sperms could be detected in regard to sperm count, motility, velocity and morphology. The only similar translocation previously reported in a male was associated with azoospermia. Recent literature correlating chromosomal aberrations and reproductive failure in the male is discussed in relation to the reported case. The importance of including the male partner in the cytogenetic investigation of couples with habitual abortion is stressed.
A patient who had recently received a therapeutic dose of Na131I showed no 99mTc activity on the scintillation camera when a pertechnetate brain scan was attempted. Subsequent experiments showed ...that, when even small amounts of 131I are present in the field of view of a scintillation camera equipped with a collimator designed for low-energy photons, counting rates from 99mTc are markedly affected.
In two patients exhibiting eunuchoid features in association with normal sized testes and complete spermatogenesis concommittant with only occasional Leydig cells between the tubuli, (proven by ...testicular biopsy) an attempt was made to elucidate the factors leading to this condition. Both patients responded with significant rise in both plasma FSH and LH after administration of synthetic GnRH indicating pituitary responsiveness. However, no rise in either FSH or LH could be observed after administration of clomiphene citrate during three weeks of treatment indicating hypothalamic unresponsiveness to chemical stimuli. Although plasma testosterone levels rose significantly after administration of Human Chorionic Gonadotropin, estradiol remained unchanged during three weeks of HCG administration. A hypothesis is discussed which defines this syndrome in these two cases as primary Leydig cells failure, expressed in the inability of these to transform testosterone into estrogens, thus depriving pituitary and hypothalamus from a proper steroidal milieu necessary to adequate functioning.
Building on the legacy of the Sloan Digital Sky Survey (SDSS-I and II), SDSS-III is a program of four spectroscopic surveys on three scientific themes: dark energy and cosmological parameters, the ...history and structure of the Milky Way, and the population of giant planets around other stars. In keeping with SDSS tradition, SDSS-III will provide regular public releases of all its data, beginning with SDSS DR8 (which occurred in Jan 2011). This paper presents an overview of the four SDSS-III surveys. BOSS will measure redshifts of 1.5 million massive galaxies and Lya forest spectra of 150,000 quasars, using the BAO feature of large scale structure to obtain percent-level determinations of the distance scale and Hubble expansion rate at z<0.7 and at z~2.5. SEGUE-2, which is now completed, measured medium-resolution (R=1800) optical spectra of 118,000 stars in a variety of target categories, probing chemical evolution, stellar kinematics and substructure, and the mass profile of the dark matter halo from the solar neighborhood to distances of 100 kpc. APOGEE will obtain high-resolution (R~30,000), high signal-to-noise (S/N>100 per resolution element), H-band (1.51-1.70 micron) spectra of 10^5 evolved, late-type stars, measuring separate abundances for ~15 elements per star and creating the first high-precision spectroscopic survey of all Galactic stellar populations (bulge, bar, disks, halo) with a uniform set of stellar tracers and spectral diagnostics. MARVELS will monitor radial velocities of more than 8000 FGK stars with the sensitivity and cadence (10-40 m/s, ~24 visits per star) needed to detect giant planets with periods up to two years, providing an unprecedented data set for understanding the formation and dynamical evolution of giant planet systems. (Abridged)
About 120 cases of XY gonadal dysgenesis have been reported on. We treated such a patient with bilateral gonadectomy. The gonadal tissue's capacity to respond to hormonal trophic stimulation was ...assessed. When the gonads were examined ultrastructurally, structures with the morphologic characteristics of stromal ovarian cells, Sertoli's cells and Leydig's cells were found. Because of the potential malignancy of the XY gonads, bilateral gonadectomy and hormonal substitution therapy are recommended for these patients. We prefer to use combined hormone replacement with sequential estrogen and progesterone rather than sequential unopposed estrogen because of the small but increased risk of endometrial hyperplasia and carcinoma after long-standing sequential therapy.
Multiphonon processes in a model quantum dot (QD) containing two electronic states and several optical phonon modes are considered taking into account both intra- and inter-level terms. The ...Hamiltonian is exactly diagonalized including a finite number of multi-phonon processes, large enough as to guarantee that the result can be considered exact in the physically important region of energies. The physical properties are studied by calculating the electronic Green's function and the QD dielectric function. When both the intra- and inter-level interactions are included, the calculated spectra allow for explanation of several previously published experimental results obtained for spherical and self-assembled QDs, such as enhanced 2LO phonon replica in absorption spectra and up-converted photoluminescence. An explicit calculation of the spectral line shape due to intra-level interaction with a continuum of acoustic phonons is presented, where the multi-phonon processes also are shown to be important. It is pointed out that such an interaction, under certain conditions, can lead to relaxation in the otherwise stationary polaron system.
We describe the first data release from the Spitzer-IRAC Equatorial Survey (SpIES); a large-area survey of similar to 115 deg(2) in the Equatorial SDSS Stripe 82 field using Spitzer during its "warm" ...mission phase. SpIES was designed to probe sufficient volume to perform measurements of quasar clustering and the luminosity function at z >= 3 to test various models for "feedback" from active galactic nuclei (AGNs). Additionally, the wide range of available multi-wavelength, multi-epoch ancillary data enables SpIES to identify both high-redshift (z >= 5) quasars as well as obscured quasars missed by optical surveys. SpIES achieves 5 sigma depths of 6.13 mu Jy (21.93 AB magnitude) and 5.75 mu Jy (22.0 AB magnitude) at 3.6 and 4.5 mu m, respectively-depths significantly fainter than the Wide-field Infrared Survey Explorer (WISE). We show that the SpIES survey recovers a much larger fraction of spectroscopically confirmed quasars (similar to 98%) in Stripe 82 than are recovered by WISE (similar to 55%). This depth is especially powerful at high-redshift (z >= 3.5), where SpIES recovers 94% of confirmed quasars, whereas WISE only recovers 25%. Here we define the SpIES survey parameters and describe the image processing, source extraction, and catalog production methods used to analyze the SpIES data. In addition to this survey paper, we release 234 images created by the SpIES team and three detection catalogs: a 3.6 mu m. only detection catalog containing similar to 6.1 million sources, a 4.5 mu m. only detection catalog containing similar to 6.5 million sources, and a dual-band detection catalog containing similar to 5.4 million sources.
Influence of some variables on the accuracy of sperm motility evaluation was studied by analyzing normal seminal specimens with the aid of themultiple exposure photography (MEP) method. Results of ...this study demonstrated the existence of variations in sperm motility between view areas of the same sample or between different samples of the same specimen. Variations were found even when the same view area was analyzed intermittently during a short period of time. Motility was practically unaffected when a regular sized drop was kept within the preparation for about 20 min. The light from the microscope neither stimulated nor depressed sperm motility when they were illuminated continuously for that period of time. Percent of motility and sperm velocity was directly related to the thickness of the examined drop when the latter ranged between zero and ten micrometers. According to these findings it is suggested that several view areas from various drops of the same specimen should be analyzed with each view area being inspected several times before motility of that field is assessed. Motility should be evaluated from drops of standard and constant thickness; otherwise major errors in sperm motility assessment are to be expected.
