Alcohol and drug use can have negative consequences on the health, economy, productivity, and social aspects of communities. We aimed to use data from the Global Burden of Diseases, Injuries, and ...Risk Factors Study (GBD) 2016 to calculate global and regional estimates of the prevalence of alcohol, amphetamine, cannabis, cocaine, and opioid dependence, and to estimate global disease burden attributable to alcohol and drug use between 1990 and 2016, and for 195 countries and territories within 21 regions, and within seven super-regions. We also aimed to examine the association between disease burden and Socio-demographic Index (SDI) quintiles.
We searched PubMed, EMBASE, and PsycINFO databases for original epidemiological studies on alcohol and drug use published between Jan 1, 1980, and Sept 7, 2016, with out language restrictions, and used DisMod-MR 2.1, a Bayesian meta-regression tool, to estimate population-level prevalence of substance use disorders. We combined these estimates with disability weights to calculate years of life lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 1990–2016. We also used a comparative assessment approach to estimate burden attributable to alcohol and drug use as risk factors for other health outcomes.
Globally, alcohol use disorders were the most prevalent of all substance use disorders, with 100·4 million estimated cases in 2016 (age-standardised prevalence 1320·8 cases per 100 000 people, 95% uncertainty interval 95% UI 1181·2–1468·0). The most common drug use disorders were cannabis dependence (22·1 million cases; age-standardised prevalence 289·7 cases per 100 000 people, 95% UI 248·9–339·1) and opioid dependence (26·8 million cases; age-standardised prevalence 353·0 cases per 100 000 people, 309·9–405·9). Globally, in 2016, 99·2 million DALYs (95% UI 88·3–111·2) and 4·2% of all DALYs (3·7–4·6) were attributable to alcohol use, and 31·8 million DALYs (27·4–36·6) and 1·3% of all DALYs (1·2–1·5) were attributable to drug use as a risk factor. The burden of disease attributable to alcohol and drug use varied substantially across geographical locations, and much of this burden was due to the effect of substance use on other health outcomes. Contrasting patterns were observed for the association between total alcohol and drug-attributable burden and SDI: alcohol-attributable burden was highest in countries with a low SDI and middle-high middle SDI, whereas the burden due to drugs increased with higher S DI level.
Alcohol and drug use are important contributors to global disease burden. Effective interventions should be scaled up to prevent and reduce substance use disease burden.
Bill & Melinda Gates Foundation and Australian National Health and Medical Research Council.
During the COVID-19 pandemic, excess mortality has been reported, while hospitalisations for acute cardiovascular events reduced. Brazil is the second country with more deaths due to COVID-19. We ...aimed to evaluate excess cardiovascular mortality during COVID-19 pandemic in 6 Brazilian capital cities.
Using the Civil Registry public database, we evaluated total and cardiovascular excess deaths, further stratified in specified cardiovascular deaths (acute coronary syndromes and stroke) and unspecified cardiovascular deaths in the 6 Brazilian cities with greater number of COVID-19 deaths (São Paulo, Rio de Janeiro, Fortaleza, Recife, Belém, Manaus). We compared observed with expected deaths from epidemiological weeks 12-22 of 2020. We also compared the number of hospital and home deaths during the period.
There were 65 449 deaths and 17 877 COVID-19 deaths in the studied period and cities for 2020. Cardiovascular mortality increased in most cities, with greater magnitude in the Northern capitals. However, while there was a reduction in specified cardiovascular deaths in the most cities, the Northern capitals showed an increase of these events. For unspecified cardiovascular deaths, there was a marked increase in all cities, which strongly correlated to the rise in home deaths (r=0.86, p=0.01).
Excess cardiovascular mortality was greater in the less developed cities, possibly associated with healthcare collapse. Specified cardiovascular deaths decreased in the most developed cities, in parallel with an increase in unspecified cardiovascular and home deaths, presumably as a result of misdiagnosis. Conversely, specified cardiovascular deaths increased in cities with a healthcare collapse.
We aimed to estimate trends in population-level adult body weight indicators in the 26 state capitals and the Federal District of Brazil.
Self-reported weight and height data of 572,437 adults were ...used to estimate the mean body mass index (BMI), and the prevalence of BMI categories ranging from underweight to morbid obesity, in Brazil's state capitals and Federal District, from 2006 to 2016, by sex. All estimates were standardized by age.
From 2006 to 2016, the main findings showed that: (i) the overall mean BMI increased from 25.4 kg/m2 to 26.3 kg/m2 in men, and from 24.5 kg/m2 to 25.8 kg/m2 in women; (ii) the overall prevalence of overweight increased from 48.1% to 57.5% in men, and from 37.8% to 48.2% in women; (iii) the overall prevalence of obesity increased from 11.7% to 18.1% in men, and from 12.1% to 18.8% in women; (iv) in general, the largest increases in overweight and obesity prevalence were found in state capitals located in the north, northeast, and central-west regions of Brazil; (v) the prevalence of severe obesity surpassed the prevalence of underweight in 22 and 9 state capitals among men and women, respectively; and (vi) the mean BMI trend was stable only in Vitória state capital in men.
The policies for preventing and treating obesity in Brazil over the past years were not able to halt the increase in obesity prevalence either in the state capitals or the Federal District. Thus, a revision of policies is warranted. Furthermore, although policies are necessary in all state capitals, our results suggest that policies are especially necessary in the north, northeast, and central-west regions' state capitals, where, in general, the largest increases in overweight and obesity prevalence were experienced.
To analyze the use of health services in the Brazilian population by sociodemographic factors, according to data from the 2013 Brazilian National Health Survey.
The study analyzed data from 205,000 ...Brazilian citizens in all age groups who participated in the Brazilian National Health Survey, a cross-sectional study carried out in 2013. Prevalence and confidence intervals were estimated for indicators related to access to and use of health services according to age group, level of education of head of household, and Brazilian macroregions.
Among individuals who sought health services in the two weeks prior to the survey, 95.3% (95%CI 94.9-95.8) received care in their first visit. Percentages were higher in the following groups: 60 years of age and over; head of household with complete tertiary education; living in the South and Southeast regions. In addition, 82.5% (95%CI 81.2-83.7) of individuals who received health care and prescriptions were able to obtain all the necessary medicines, 1/3 of them from SUS. Less than half the Brazilian population (44.4%; 95%CI 43.8-45.1) visited a dentist in the 12 months prior to the survey, with smaller percentages among the following groups: 60 years of age or older; head of household with no education or up to incomplete elementary; living in the North region of Brazil.
People living in the South and Southeast regions still have greater access to health services, as do those whose head of household has a higher level of education. The (re)formulation of health policies to reduce disparities should consider differences encountered between regions and social levels.
Descrever o uso de serviços de saúde na população brasileira segundo fatores sociodemográficos, de acordo com dados da Pesquisa Nacional de Saúde, 2013.
Foram analisados dados referentes a 205 mil brasileiros, de todas as faixas etárias, que participaram da Pesquisa Nacional de Saúde, estudo transversal conduzido em 2013. Calcularam-se as prevalências e seus intervalos de confiança para indicadores referentes ao acesso e a utilização dos serviços de saúde, segundo grupos de idade, nível de instrução do chefe da família e macrorregiões do país.
Dentre os indivíduos que procuraram o serviço de saúde nas duas semanas prévias à pesquisa, 95,3% (IC95% 94,9-95,8) conseguiu usá-lo na primeira vez que procurou. As proporções foram maiores: no grupo de 60 anos ou mais; cujo chefe da família tinha nível superior completo; e nas regiões Sul e Sudeste. Ainda, dos indivíduos atendidos e que tiveram medicamentos receitados, 82,5% (IC95% 81,2-83,7) conseguiram obter todos os medicamentos, sendo 1/3 pelo SUS. Menos da metade da população brasileira (44,4%; IC95% 43,8-45,1) consultou um dentista nos 12 meses anteriores à pesquisa, com proporções menores entre: indivíduos com 60 anos ou mais; cujo chefe da família não possuía nível de instrução ou tinha até o fundamental incompleto; e indivíduos que residiam na região Norte do país.
Pessoas que residem nas regiões Sul e Sudeste ainda possuem maior acesso aos serviços de saúde, bem como aquelas cujo chefe da família tem maior nível de instrução. A (re)formulação de políticas de saúde no intuito de reduzir disparidades deve considerar as diferenças regionais e entre níveis sociais encontradas.
The programme is integrated with primary care and US$150 million was invested in the first year.2,3 The objective for the health academies programme is to overcome structural barriers to physical ...activity and healthy habits, especially among vulnerable populations.2,3 The strategic plan to tackle NCDs also encourages increased provision of physical activity in schools through partnerships with the Ministry of Sports and the Ministry of Education.2,3 Furthermore, educational measures that foster healthy habits and the practice of daily physical activity are underway as part of the legacy of two major sporting events that will be held in Brazil: the 2014 World Cup and the Olympic Games in 2016.2,3 The goals of the national plan will be monitored by Brazil's system of NCD surveillance, household population surveys every 5 years, annual telephone surveys, information systems, and other studies.
The aims of this study were as follows: to estimate the mortality and years of life lost, assessed by disability-adjusted life years (DALYs), due to breast cancer attributable to physical inactivity ...in Brazilian women; to compare the estimates attributable to physical inactivity and to other modifiable risk factors; and to analyse the temporal evolution of these estimates within Brazilian states over 25 years (1990-2015), compared with global estimates. Databases from the Global Burden of Disease Study for Brazil, Brazilian states, and other parts of the world were used. Physical inactivity has contributed to a substantial number of deaths (1990: 875; 2015: 2,075) and DALYs (1990: 28,089; 2015: 60,585) due to breast cancer in Brazil. Physical inactivity was responsible for more deaths and DALYs (~12.0%) due to breast cancer than other modifiable risk factors (~5.0%). The Brazilian states with better socioeconomic indicators had higher age-standardized rates of mortality and morbidity due to breast cancer attributable to physical inactivity. From 1990 to 2015, mortality due to breast cancer attributable to physical inactivity increased in Brazil (0.77%; 95%U.I.: 0.27-1.47) and decreased (-2.84%; 95%U.I.: -4.35 - -0.10) around the world. These findings support the promotion of physical activity in the Brazilian female population to prevent and manage breast cancer.
To estimate the prevalence of bullying among Brazilian students from the aggressor's perspective and to analyze its association with individual and contextual variables.
This was a cross-sectional ...population-based study carried out with data from the National Survey on Student Health. A total of 109,104 students attending eight grade in public and private schools were included. Data were collected through a self-applied questionnaire. A model of association between bullying and variables in the following domains was tested: sociodemographics, risk behaviors, mental health, and family context. Univariate and multivariate analyses were also performed.
The prevalence of aggressors in bullying situations was 20.8%. The following variables remained associated in the final multivariate model: male gender (OR: 1.87; 95% CI: 1.79–1.94), lower participation of 16-year-old students (OR: 0.66; 95% CI: 0.53–0.82), and students from private schools (OR: 1.33; 95% CI: 1.27–1.39). Most aggressors reported feeling lonely (OR: 1.22; 95% CI: 1.16–1.28), insomnia episodes (OR: 1.21; 95% CI: 1.14–1.29), and a high prevalence of physical violence in the family (OR: 1.97 95% CI: 1.87–2.08). Aggressors missed classes more frequently (OR: 1.45; 95% CI: 1.40–1.51), and they regularly consumed more tobacco (OR: 1.21; 95% CI: 1.12–1.31), alcohol (OR: 1.85; 95% CI: 1.77–1.92), and illegal drugs (OR: 1.91; 95% CI: 1.79–2.04); they also demonstrated increased sexual intercourse (OR: 1.49 95% CI: 1.43–1.55) and regular exercise (OR: 1.20; 95% CI: 1.16–1.25).
The data indicate that bullying is an important aspect that affects the learning-teaching process and the students’ health.
Estimar a prevalência de bullying, sob a perspectiva do agressor, em escolares brasileiros, e analisar sua associação com variáveis individuais e de contexto.
Estudo transversal, de base populacional, com dados da Pesquisa Nacional de Saúde do Escolar. Participaram 109.104 estudantes do 9° ano do Ensino Fundamental de escolas públicas e privadas. A coleta de dados ocorreu por meio de um questionário autoaplicável. Foi testado modelo de associação entre o bullying e variáveis nos seguintes domínios: sociodemográfico, comportamentos de risco, saúde mental e contexto familiar, bem como realizadas analises uni e multivariada.
A prevalência de agressores em situações de bullying foi de 20,8%. No modelo final multivariado permaneceram as seguintes variáveis associadas: sexo masculino (OR: 1,87; IC 95%: 1,79-1,94), menor participação de escolares de 16 anos (OR: 0,66; IC 95%: 0,53-0,82), estudantes de escola privada (OR 1,33 IC95% 1,27-1,39). A maioria dos agressores relatou se sentir solitário (OR: 1,22; IC 95%: 1,16-1,28), com episódios de insônia (OR: 1,21; IC 95%: 1,14-1,29) e alta prevalência de sofrer violência física familiar (OR: 1,97 IC 95%: 1,87-2,08). Os agressores faltam mais às aulas (OR: 1,45; IC 95%: 1,40-1,51), consomem regularmente mais tabaco (OR: 1,21; IC 95%: 1,12-1,31), álcool (OR: 1,85; IC 95%: 1,77-1,92) e drogas ilícitas (OR: 1,91; IC 95%: 1,79-2,04), tem relação sexual OR: 1,49 IC95% 1,43-1,55) e praticam atividade física regular (OR1,20 IC95% 1,16-1,25).
Os dados indicam que a prática do bullying é aspecto relevante que interfere no processo ensino-aprendizagem e na saúde dos escolares.
To assess whether sex, education level, and health insurance affect the use of health services among the adult Brazilian population with chronic noncommunicable diseases (NCD).
Data from a ...cross-sectional survey were analyzed, the National Health Survey (PNS). Frequency of use of services in the population that referred at least one NCD were compared with the frequency from a population that did not report NCD, according to sex, education level, health insurance, and NCD number (1, 2, 3, 4, or more). The prevalence and prevalence ratios were calculated crude and adjusted for sex, age, region, and 95% confidence intervals.
The presence of a noncommunicable disease was associated with increase in hospitalizations in the last 12 months, in 1.7 times (95%CI 1.53-1.9). Failing to perform usual activities in the last two weeks for health reasons was 3.1 times higher in NCD carriers (95%CI 2.78-3.46); while the prevalence of medical consultation in the last 12 months was 1.26 times higher (95%CI 1.24-1.28). NCD carriers make more use of health services, as well as women, people with higher number of comorbidities, with health insurance, and higher education level.
NCD carriers make more use of health services, as well as women, people with higher number of comorbidities, with health insurance, and higher education level.