We present new constraints on sub-GeV dark-matter particles scattering off electrons based on 6780.0 kg d of data collected with the DarkSide-50 dual-phase argon time projection chamber. This ...analysis uses electroluminescence signals due to ionized electrons extracted from the liquid argon target. The detector has a very high trigger probability for these signals, allowing for an analysis threshold of three extracted electrons, or approximately 0.05 keVee. We calculate the expected recoil spectra for dark matter-electron scattering in argon and, under the assumption of momentum-independent scattering, improve upon existing limits from XENON10 for dark-matter particles with masses between 30 and 100 MeV/c^{2}.
Atherosclerosis is a disease of the arteries in which fatty plaques develop on the inner arterial wall, which eventually obstructs blood flow. Identified risk factors for atherosclerosis include ...genetics, diet, lifestyle, smoking, circulating lipid and cholesterol levels, and molecular and circulating signals of chronic vascular inflammation. The link between flavonoids and atherosclerosis is based partly on the evidence that some flavonoids possess antioxidant properties and have been shown to be potent inhibitors of LDL oxidation in vitro. Hypercholesterolemia, a significant cardiovascular risk factor is prevalent in the American population. Grape seed proanthocyanidin extracts are known to exhibit a broad spectrum of chemopreventive and cardioprotective properties against oxidative stress. A recent study has shown that a combination of IH636 grape seed proanthocyanidin extract (GSPE) and a niacin-bound chromium (NBC) can decrease total cholesterol, LDL and oxidized LDL levels in hypercholesterolemic human subjects. In this study, we assessed the efficacy of GSPE supplementation in hamsters, singly and in combination with NBC, since these animals have a similar lipid profile to hypercholesterolemic humans when fed a hypercholesterolemic diet of 0.2% cholesterol and 10% coconut oil (HCD). After 10 weeks of feeding HCD, these animals developed foam cells, which is a biomarker of early stages of atherosclerosis. Atherosclerosis (% of aorta covered with foam cells) was reduced by approximately 50% and 63% following supplementation of these animals with 50 mg/kg and 100 mg/kg of GSPE, respectively, in conjunction with a HCD, while approximately 32% reduction was observed following supplementation of GSPE plus NBC. A range of 7-9 animals was used in each study group. GSPE alone and in combination with NBC exerted a pronounced effect on the cholesterol, and triglyceride levels, as well as oxidative lipid damage as demonstrated by the formation of thiobarbituric acid reactive substances (TBARS). This data demonstrates that GSPE and NBC may provide significant health benefits by dramatically ameliorating the incidence of atherosclerosis as demonstrated by reducing the formation of foam cells.
.
Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid ...Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant
39
Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of
>
3
×
10
9
is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than
<
0
.
1
events (other than
ν
-induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured
in situ
, giving sensitivity to WIMP-nucleon cross sections of
1
.
2
×
10
-
47
cm
2
(
1
.
1
×
10
-
46
cm
2
) for WIMPs of 1 TeV/c
2
(10 TeV/c
2
) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.
A liquid argon time projection chamber, constructed for the Argon Response to Ionization and Scintillation (ARIS) experiment, is exposed to the highly collimated and quasimonoenergetic LICORNE ...neutron beam at the Institut de Physique Nucléaire d’Orsay (IPNO) in order to study the scintillation response to nuclear and electronic recoils. An array of liquid scintillator detectors, arranged around the apparatus, tag scattered neutrons and select nuclear recoil energies in the 7, 120 keV energy range. The relative scintillation efficiency of nuclear recoils is measured to high precision at null field, and the ion-electron recombination probability is extracted for a range of applied electric fields. Single-scattered Compton electrons, produced by gammas emitted from the deexcitation of Li*7 in coincidence with the beam pulse, along with calibration gamma sources, are used to extract the recombination probability as a function of energy and electron drift field. The ARIS results are compared with three recombination probability parametrizations (Thomas-Imel, Doke-Birks, and PARIS), allowing for the definition of a fully comprehensive model of the liquid argon response to nuclear and electronic recoils down to the few-keV range. The constraints provided by ARIS to the liquid argon response at low energy allow the reduction of systematics affecting the sensitivity of dark matter search experiments based on liquid argon.
This paper articulates the complexities of adaptively managing Delaware River water resources to meet shifting priorities of drinking water supply, drought mitigation and flood mitigation, as well as ...conflicting stakeholder interests. In particular, the paper examines the short-term and long-term programs that comprise the Delaware River Basin Commission's (DRBC) and the 1954 US Supreme Court Decree parties' successful adaptive management approach that seeks to balance the growing list of demands for water resources management, including drinking water supply, drought management, flood control and cold water fisheries protection. Review of the DRBC's adaptive governance approach reveals the critical complexities of designing experimental, yet science-driven management approaches and effectively engaging various sets of stakeholders in the associated decision-making processes.
Institutions for Interstate Water Resources Management1 Mandarano, Lynn A.; Featherstone, Jeffrey P.; Paulsen, Kurt
Journal of the American Water Resources Association,
February 2008, 20080201, Letnik:
44, Številka:
1
Journal Article
: This paper evaluates alternative approaches to management of interstate water resources in the United States (U.S.), including interstate compacts, interstate associations, federal‐state ...partnerships, and federal‐interstate compacts. These governance structures provide alternatives to traditional federalism or U.S. Supreme Court litigation for addressing problems that transcend political boundaries and functional responsibilities. Interstate compacts can provide a forum for ongoing collaboration and are popular mechanisms for allocating water rights among the states. Federal‐interstate compacts, such as the Delaware River Basin Compact and federal‐state partnerships, such as the National Estuary Program, are also effective and complementary approaches to managing water resources. However, all of these approaches can only make modest improvements in managing water resources given the complicated and fragmented nature of our federalist system of government.
DarkSide is a multi-stage program devoted to direct searches of Dark Matter particles with detectors based on double phase liquid Argon Time Projection Chamber. The DarkSide-50 setup is running ...underground at the Laboratori Nazionali del Gran Sasso. First it was operated with Atmospheric Argon and during that run (1422 ± 67) kg×d of truly background-free exposure has been accumulated. Obtained data made it possible to set a 90% C.L. upper limit on the WIMP-nucleon cross section of 6.1 × 10−44 cm2 (for a WIMP mass of 100 GeV/c2). Presently the detector is filled with Underground Argon, which is depleted in 39Ar by a factor of (1.4 ± 0.2)×103 with respect to Atmospheric Argon. Acquired so far (2616 ± 43) kg×d (71 live days) in combination with the data from the Atmospheric Argon run give us the 90% C.L. upper limit on the WIMP-nucleon spin-independent cross section of 2.0×10−44 cm2 for a WIMP mass of 100 GeV/c2. Up to date this is the best limit obtained with an argon target.
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