In this paper, we present a technique for tracking groups of partials in musical signals, based on networks of adaptive oscillators. We show how synchronization of adaptive oscillators can be ...utilized to detect periodic patterns in outputs of a human auditory model and thus track stable frequency components (partials) in musical signals. We present the integration of the partial tracking model into a connectionist system for transcription of polyphonic piano music. We provide a short overview of our transcription system and present its performance on transcriptions of several real piano recordings.
The paper presents the development of EthnoMuse: multimedia digital library of Slovenian folk music and dance culture. The main scope of the project concerns the digitization of production and ...post-production processes that relate to collecting, documenting and archiving of folk heritage and development of multimedia applications for various content types (folk song, music and dance) and formats (image, audio, video, notation, MIDI etc.). The main objective of this paper is to discuss the former, focusing on the conceptual design of a flexible data model the archive is based on. We also briefly describe the tools developed to support the workflow of researchers involved in collecting and archiving of folk music related contents.
Educational hypermedia: an evaluation study Kavcic, A.; Privosnik, M.; Marolt, M. ...
11th IEEE Mediterranean Electrotechnical Conference (IEEE Cat. No.02CH37379),
2002
Conference Proceeding
The role of computers in education has changed significantly in the last years. Educational systems have exceeded passive teaming systems and now actively participate in the teaming process. ...Web-based educational systems, for example, supported by incorporated intelligent tutoring techniques, are able to adapt information and its presentation to each individual user, and dynamically support navigation through the hypermedia material. This paper deals with the evaluation of educational hypermedia. An adaptive hypermedia system was developed and implemented for this purposes. The system is based on a concept domain model and also considers the elements of knowledge uncertainty in the process of user modelling. Both models are used for system adaptation, which builds on adaptive link insertion in addition to traditional adaptive navigation support technologies, like annotation and direct guidance. The system has been evaluated in a real environment and the results of the experiments are discussed here. In the paper, adaptive hypermedia systems in general are described first. Then our system is described, which was used in the evaluation study. In the end, the experiments are described and the results analysed in details.
On detecting note onsets in piano music Marolt, M.; Kavcic, A.; Privosnik, M. ...
11th IEEE Mediterranean Electrotechnical Conference (IEEE Cat. No.02CH37379),
2002
Conference Proceeding
This paper presents an overview of our researches in the use of connectionist systems for transcription of polyphonic piano music and concentrates on the issue of onset detection in musical signals. ...We propose a new technique for detecting onsets in a piano performance. The technique is based on a combination of a bank of auditory filters, a network of integrate-and-fire neurons and a multilayer perceptron. Such a structure introduces several advantages over the standard peak-picking onset detection approach and we present its performance on several synthesized and real piano recordings. Results show that our approach represents a viable alternative to existing onset detection algorithms.
Emergent behavior results in complex systems. Emergent behavior can be observed in various systems - a colony of ants, an economy, a brain or a large network of computers - these are all systems with ...complex emergent behavior. The behavior of a complex system as a whole emerges in a highly nonlinear manner from the behaviors of the low level constituent elementary units. This makes traditional linear analysis difficult, if not impossible. We focus on emergent properties of massive multi-agent systems. We present how these properties can be utilized to model global behavior of the system.
In patients who require venom immunotherapy (VIT), there is a need to identify underlying mast cell (MC) disorders since these may affect the risk and severity of future sting reactions and the ...long-term effectiveness of VIT.
1319 individuals with Hymenoptera venom allergy (HVA) who needed VIT from referral centers in Slovenia, Austria, Croatia, and Poland underwent examination for KIT p.D816V in peripheral blood leukocytes (PBL) using a highly sensitive PCR test and tryptase genotyping by digital droplet PCR. We also included 183 control individuals with large local reactions (LLRs) to Hymenoptera stings and with asymptomatic sensitization to Hymenoptera venoms.
285 of 1319 individuals recommended for VIT (21.6%) were positive for KIT p.D816V in PBL, preferably those who present with severe reaction (33.9% n = 207 of 610 with Ring-Messmer grade 3-4 vs. 11% n = 78 of 709 with Grade 1-2; p < .0001), whereas only 1.3% (n = 2 of 152) of controls with LLR and none with asymptomatic sensitization (n = 31) had KIT p.D816V. KIT p.D816V allelic burden was higher in those with severe reaction (median 0.018% n = 207 in Grade 3-4 vs. 0.001% n = 78 in Grade 1-2; p < .0001), and the majority had normal baseline serum tryptase levels (69% n = 196 of 285). All KIT p.D816V-positive individuals (n = 41) who underwent bone marrow (BM) biopsy were found to have underlying clonal diseases, principally BM mastocytosis. HαT was also associated with severe HVA and symptoms (p < .01), and remarkably, 31.0% (n = 31 of 100) were found to have concomitant KIT p.D816V. Concomitant HαT and KIT p.D816V showed an additive effect, and having both was associated with the highest risk for severe HVA, even higher than having either HαT or KIT p.D816V alone (OR = 3.8; p < .01).
By employing prospective universal tryptase genotyping and examination for KIT p.D816V in PBL in large HVA populations, we have demonstrated a high burden of clonal MC disorders and HαT in patients who require VIT.
Tumour necrosis factor-alpha (TNF-α) inhibitors are widely used in the management of patients with rheumatoid arthritis (RA) and spondylarthritides. However, TNF-α inhibition may lead to adverse ...events, including liver injury. The RA patients are frequently treated with several potentially hepatotoxic drugs concomitantly; hence, a causative link between TNF-α inhibitors and liver injury is usually difficult to establish. We report two cases of RA patients who developed histologically manifest liver injury shortly after the introduction of treatment with two different TNF-α inhibitors. Furthermore, we present the analysis of the laboratory data from the BioRx.si registry (the Slovenian national registry of rheumatologic patients treated with biologicals) and provide evidence that elevated levels of serum aminotransferase can be observed in patients treated with TNF-α inhibitors. Additionally, our analysis suggests no significant differences between the impact of adalimumab and etanercept on aminotransferase levels. Although the use of TNF-alpha inhibitors is safe and efficient, we suggest that continuous careful monitoring of aminotransferase levels in patients treated with these agents is probably warranted.
