The first few decades of the twenty-first century have posed various challenges to humankind such as the worldwide impact of the changing patterns of globalization processes, economic crises, the ...pandemic, the war in Ukraine, and the specter of deglobalization illustrate. The unknown and unpredictable future is a reason for utmost concern for the contemporary society that Byung-Chul Han characterizes as an “achievement society”—one that is dominated by “excessive positivity” and that has evolved into a “doping society”. This “palliative society” is such because it is unable to cope with pain, and it is marked by a kind of permanent analgesia that prevents urgent reforms from taking place. In this essay, I examine how Pope Francis’s encyclical letters Laudato Si’ (2015) and Fratelli Tutti (2020)—by calling for an integral ecology (which connects environmental, economic, political, social, cultural, and ethical issues), social friendship, solidarity, and the common good—instill hope in the burnout society that Han reflects upon, urge action toward, and encourage changes to overcome in the current environmental and human crisis, as well as to building a diverse future that is not palliative.
Recent advances in biological imaging techniques and the enormous amount of data they generate call for the development of computational tools for efficient and reliable high-throughput analysis. ...Several software applications with this functionality are available, and one of the most commonly used is ImageJ. Here, we present two independent macros (WH_NJ and SA_NJ) for automating and facilitating the analysis of images acquired from two in vitro assays frequently used in cancer studies and drug screening: the wound-healing and soft-agar assays. These two algorithms combine, in a single command, the steps required for the individual analysis of each image using ImageJ. WH_NJ and SA_NJ allow fast, reproducible data analysis without the experimental bias inherent in manual analyses, thus guaranteeing the robustness and reliability of the results.
Stressful events during prenatal and postpartum have been associated with an increase in the susceptibility to the onset of various diseases, threatening mental and physical health of mother and ...baby. The aim of this study was to synthesize and analyze the literature related to risk factors associated with stress symptoms during pregnancy and immediate postpartum by means of an integrative review. The search was conducted from January 2013 to July 2020, consulting the following databases: PubMed, PsycINFO, CINAHL, Web of Science and LILACS. In total, 1,677 studies were identified, resulting in 38 articles included in this review. The risk factors most associated with stress in pregnancy and postpartum were related to emotional factors (including mental health, traumatic events and obstetric complications); social and economic factors; mother's health conditions and life style behaviors, and social support and partner related stress. The results are discussed under the light of the biopsychosocial model, which proposes that biological, psychological, and social domains should be considered in order to minimize psychosocial risk conditions. It is concluded that strategies to promote psychological care, education, additional social support and health behaviors should be considered to prevent adverse birth outcomes and to increase maternal well-being.
•Earth-based mortars with bamboo particles (EMB) for plastering are evaluated experimentally.•The life cycle GHG emissions of EMB plastering are assessed.•The increased bamboo content reduces GHG ...emissions and improves the performance of EMB.•The plastering service life severely affects the final results of GHG emissions.•Strategies related to the CE to reduce the GHG emissions of EMB are presented.
This research aims at characterizing and evaluating the physical, mechanical, and thermal properties and the greenhouse gas (GHG) emissions in the life cycle of earth-based mortars with bamboo particles (EMB). Four EMB mixtures were developed with bamboo particles’ volume fractions of 0%, 3%, 6%, and 9%. The EMB mortars were characterized in terms of physical, mechanical and thermal properties. The Life Cycle GHG Emissions Assessment methodology was used considering a cradle-to-grave scope with the proposal of an eco-efficient indicator. Reduction in the GHG emissions for the EMB ranged from 21% to 113% depending on the chosen reference conventional mortar (made of cement and hydrated lime) and the evaluated scenario considered. It was verified that the EMB with 9% bamboo particles reached a 30% efficiency indicator improvement when compared with the EMB without bamboo. This mixture presented the most significant building plastering potential for the construction industry that seeks circular and low-carbon solutions. Finally, strategies related to Circular economy for the reduction of GHG emissions of EMB mixtures are proposed in this study.
The present study aimed to evaluate a hypothetical Leishmania amastigote-specific protein (LiHyp1), previously identified by an immunoproteomic approach performed in Leishmania infantum, which showed ...homology to the super-oxygenase gene family, attempting to select a new candidate antigen for specific serodiagnosis, as well as to compose a vaccine against VL.
The LiHyp1 DNA sequence was cloned; the recombinant protein (rLiHyp1) was purified and evaluated for its antigenicity and immunogenicity. The rLiHyp1 protein was recognized by antibodies from sera of asymptomatic and symptomatic animals with canine visceral leishmaniasis (CVL), but presented no cross-reactivity with sera of dogs vaccinated with Leish-Tec, a Brazilian commercial vaccine; with Chagas' disease or healthy animals. In addition, the immunogenicity and protective efficacy of rLiHyp1 plus saponin was evaluated in BALB/c mice challenged subcutaneously with virulent L. infantum promastigotes. rLiHyp1 plus saponin vaccinated mice showed a high and specific production of IFN-γ, IL-12, and GM-CSF after in vitro stimulation with the recombinant protein. Immunized and infected mice, as compared to the control groups (saline and saponin), showed significant reductions in the number of parasites found in the liver, spleen, bone marrow, and in the paws' draining lymph nodes. Protection was associated with an IL-12-dependent production of IFN-γ, produced mainly by CD4 T cells. In these mice, a decrease in the parasite-mediated IL-4 and IL-10 response could also be observed.
The present study showed that this Leishmania oxygenase amastigote-specific protein can be used for a more sensitive and specific serodiagnosis of asymptomatic and symptomatic CVL and, when combined with a Th1-type adjuvant, can also be employ as a candidate antigen to develop vaccines against VL.
This research paper analyzes the stability of raw cow milk in the alcohol test and seeks to understand to know the factors that influence milk stability and the occurrence of unstable non-acid milk. ...Milk samples were collected from the cooling tanks of rural farmers in the state of Paraná twice in summer and twice in winter. The farms were classified according to the production system: pasture with supplementation and feedlot. The following variables were analyzed: stability in the alcohol test, titratable acidity, ionized calcium concentration (iCa), chemical composition of milk, somatic cell count and standard plate count. The results showed that milk stability was greater in winter
summer, when the milk contained higher iCa, and in the feedlot
pasture system. The Pearson Correlation between variables (ethanol stability, milk composition, iCa, cooling tank temperature, milk volume, number of milking, number of cows milked, fat/protein ratio, distance and travel time) were analyzed. Stability was negatively correlated with iCa concentration and positively with lactose content. Logistic regression of the risk of unstable non-acid milk at 72% alcohol (UNAM
) showed that only iCa and lactose were determinants, while evaluation of the same risk at 78% alcohol revealed iCa, titratable acidity, lactose and milk urea nitrogen as risk factors. Under the dairy farming conditions of Paraná state, the frequency of UNAM
was low (12.16%) and was higher in summer and in pasture systems with supplementation. In conclusion, in dairy herds bred with high technological level, with adequate nutritional and health management, the frequency of UNAM is low and is related to nutritional management abnd, perhaps, heat stress, factors that alter iCa and lactose levels.
Previous studies on health in prison facilities have determined that imprisonment has adverse effects on both physical and emotional well-being. Therefore, the introduction of public health measures ...is encouraged. This study aimed to (a) evaluate the levels of physical activity and the health condition of a sample of Brazilian prisoners and (b) determine the predictors of low physical activity. An observational and cross-sectional study was developed following the STROBE checklist. Data collection took place between June and November 2019 in a maximum-security Brazilian prison institution. This study’s final sample included 220 people selected through convenience sampling, of which 115 (53.2%) were aged 18 to 29 years, followed by 79 (36.6%) aged 30 to 44 years and 22 (10.2%) aged 45 to 59 years old. Overall, 64.3% of participants failed to meet the World Health Organization (WHO) recommendation for physical activity at least 150–300 min of moderate-intensity or 75 min of vigorous-intensity aerobic physical activity per week. The majority reported unhealthy food consumption (116; 53.7%). Regarding body mass index (BMI), 50.2% of individuals were classified as eutrophic, 38.1% were overweight and 11.6% were obese. Older age (AOR: 0.95; CI95%: 0.92–0.99; p = 0.01) and sitting time (AOR: 0.74; CI95%: 0.65–0.85; p < 0.01) were associated with low adherence to physical activity. Our results highlight the importance of practicing physical activity within the prison context and the need for institutional programs that promote regular physical activity.
How I became what I am Bessa, Karla Adriana Martins
Estudos feministas,
2017, Letnik:
25, Številka:
1
Journal Article
Recenzirano
Odprti dostop
The article analyzes the political and theoretical potential of cinematographic language to express and rebuild the relationship between sexual and gender differences. As cultural products, the three ...films analyzed -A Casa Assassinada(1972),Sunday, bloody Sunday(1971) andLes Amities Particulières(1964) - allude to feminist issues of the time, as well as instigating a reading of gender beyond the narratives, by historicizing the visibility of the female body, heteronormativity, and the subversiveness of forbidden loves as represented through the films’ structure. The text argues, from a queer perspective, that the aesthetic nature oftwist cinema, within the limits of each style and period, was precisely the boldness to run risks in its visual grammar, not making political concessions in challenging the moral canons of current society.
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