Political sectarianism in America Finkel, Eli J; Bail, Christopher A; Cikara, Mina ...
Science (American Association for the Advancement of Science),
2020-Oct-30, 2020-10-30, 20201030, Letnik:
370, Številka:
6516
Journal Article
Recenzirano
A poisonous cocktail of othering, aversion, and moralization poses a threat to democracy
Political polarization, a concern in many countries, is especially acrimonious in the United States (see the ...first box). For decades, scholars have studied polarization as an ideological matter—how strongly Democrats and Republicans diverge vis-à-vis political ideals and policy goals. Such competition among groups in the marketplace of ideas is a hallmark of a healthy democracy. But more recently, researchers have identified a second type of polarization, one focusing less on triumphs of ideas than on dominating the abhorrent supporters of the opposing party (
1
). This literature has produced a proliferation of insights and constructs but few interdisciplinary efforts to integrate them. We offer such an integration, pinpointing the superordinate construct of political sectarianism and identifying its three core ingredients: othering, aversion, and moralization. We then consider the causes of political sectarianism and its consequences for U.S. society—especially the threat it poses to democracy. Finally, we propose interventions for minimizing its most corrosive aspects.
E-cigarette usage is increasing, especially among the young, with both the general population and physicians perceiving them as a safe alternative to tobacco smoking. Worryingly, e-cigarettes are ...commonly used by pregnant women. As nicotine is known to adversely affect children in utero, we hypothesized that nicotine delivered via e-cigarettes would negatively affect lung development. To test this, we developed a mouse model of maternal e-vapor (nicotine and nicotine-free) exposure and investigated the impact on the growth and lung inflammation in both offspring and mothers. Female Balb/c mice were exposed to e-fluid vapor containing nicotine (18 mg/ml nicotine E-cigarette E-cig18, equivalent to two cigarettes per treatment, twice daily,) or nicotine free (E-cig0 mg/ml) from 6 weeks before mating until pups weaned. Male offspring were studied at Postnatal Day (P) 1, P20, and at 13 weeks. The mothers were studied when the pups weaned. In the mothers' lungs, e-cigarette exposure with and without nicotine increased the proinflammatory cytokines IL-1β, IL-6, and TNF-α. In adult offspring, TNF-α protein levels were increased in both E-cig18 and E-cig0 groups, whereas IL-1β was suppressed. This was accompanied by global changes in DNA methylation. In this study, we found that e-cigarette exposure during pregnancy adversely affected maternal and offspring lung health. As this occurred with both nicotine-free and nicotine-containing e-vapor, the effects are likely due to by-products of vaporization rather than nicotine.
The hydrological connectivity of freshwater ecosystems in the Amazon basin makes them highly sensitive to a broad range of anthropogenic activities occurring in aquatic and terrestrial systems at ...local and distant locations. Amazon freshwater ecosystems are suffering escalating impacts caused by expansions in deforestation, pollution, construction of dams and waterways, and overharvesting of animal and plant species. The natural functions of these ecosystems are changing, and their capacity to provide historically important goods and services is declining. Existing management policies—including national water resources legislation, community‐based natural resource management schemes, and the protected area network that now epitomizes the Amazon conservation paradigm—cannot adequately curb most impacts. Such management strategies are intended to conserve terrestrial ecosystems, have design and implementation deficiencies, or fail to account for the hydrologic connectivity of freshwater ecosystems. There is an urgent need to shift the Amazon conservation paradigm, broadening its current forest‐centric focus to encompass the freshwater ecosystems that are vital components of the basin. This is possible by developing a river catchment‐based conservation framework for the whole basin that protects both aquatic and terrestrial ecosystems.
Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations’ energy growth strategies. Feasibility studies of hydropower plants typically ignore ...the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local “direct” effects (through changes in ET within the watershed) and the potential regional “indirect” effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world’s largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4–8% and 10–12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6–36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry’s own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests.
Phosphatidylinositol-3-kinases (PI3K) γ and δ are preferentially enriched in leukocytes, and defects in these signaling pathways have been shown to impair T cell activation. The effects of PI3Kγ and ...PI3Kδ on alloimmunity remain underexplored. Here, we show that both PI3Kγ
and PI3Kδ
mice receiving heart allografts have suppression of alloreactive T effector cells and delayed acute rejection. However, PI3Kδ mutation also dampens regulatory T cells (Treg). After treatment with low dose CTLA4-Ig, PI3Kγ
, but not PI3Κδ
, recipients exhibit indefinite prolongation of heart allograft survival. PI3Kδ
Tregs have increased apoptosis and impaired survival. Selective inhibition of PI3Kγ and PI3Kδ (using PI3Kδ and dual PI3Kγδ chemical inhibitors) shows that PI3Kγ inhibition compensates for the negative effect of PI3Kδ inhibition on long-term allograft survival. These data serve as a basis for future PI3K-based immune therapies for transplantation.Phosphatidylinositol-3-kinases (PI3K) γ and δ are key regulators of T cell signaling. Here the author show, using mouse heart allograft transplantation models, that PI3Kγ or PI3Kδ deficiency prolongs graft survival, but selective inhibition of PI3Kγ or PI3Kδ reveals alternative transplant survival outcomes post CTLA4-Ig treatment.
Land-use regulations are a critical component of forest governance and conservation strategies, but their effectiveness in shaping landholder behaviour is poorly understood. We conducted a spatial ...and temporal analysis of the Brazilian Forest Code (BFC) to understand the patterns of regulatory compliance over time and across changes in the policy, and the implications of these compliance patterns for the perceived costs to landholders and environmental performance of agricultural landscapes in the southern Amazon state of Mato Grosso. Landholdings tended to remain in compliance or not according to their status at the beginning of the study period. The perceived economic burden of BFC compliance on soya bean and beef producers (US$3–5.6 billion in net present value of the land) may in part explain the massive, successful campaign launched by the farm lobby to change the BFC. The ecological benefits of compliance (e.g. greater connectivity and carbon) with the BFC are diffuse and do not compete effectively with the economic benefits of non-compliance that are perceived by landholders. Volatile regulation of land-use decisions that affect billions in economic rent that could be captured is an inadequate forest governance instrument; effectiveness of such regulations may increase when implemented in tandem with positive incentives for forest conservation.
Inland fisheries underpin food security in many tropical countries. The most productive inland fisheries in tropical and subtropical developing countries occur in large river–floodplain systems that ...are often impacted by land cover changes. However, few studies to date have assessed the effects of changes in floodplain land cover on fishery yields. Here, we integrated fisheries and satellite‐mapped habitat data to evaluate the effects of floodplain deforestation on fishery yields in 68 floodplain lake systems of the lower Amazon River, representing a wide range in relative amounts of woody, herbaceous and non‐vegetated land cover. We modelled relative fish yields (fish capture per unit effort CPUE) in the floodplain lakes as a function of the relative amounts of forest, shrub, aquatic macrophyte and bare/herbaceous habitats surrounding them. We found that forest amount was positively related (p = .0003) to multispecies CPUE. The validity of these findings was supported by rejection of plausible alternative causative mechanisms involving habitat‐related differences in amount of piscivores, fishing effort, lake area, and habitat effects on CPUE of the nine taxa dominating multispecies yields. Our results provide support to the idea that removal of floodplain forests reduces fishery yields per unit effort. Increased protection of floodplain forests is necessary to maintain the food, income and livelihood security services provided by large river–floodplain fisheries.
Communities throughout the globe are increasingly being given the responsibility of resource management, making it necessary to understand the factors that lead to success in community-based ...management (CBM). Here, we assessed whether and how institutional design principles affect the ecological outcomes of CBM schemes for
Arapaima
sp., an important common-pool fishery resource of the Amazon Basin. We quantified the degree of presence of Ostrom’s (Science 325:419–422, 1990) institutional design principles in 83 communities using a systematic survey, and quantitatively linked the design principles to a measure of ecological outcome (arapaima density) in a subset of 39 communities to assess their influence. To understand regional patterns of institutional capacity for CBM, we evaluated the degree of presence of each principle in all 83 communities. The principle scores were positively related to arapaima density in the 39 CBM schemes, explaining about half of the variation. Design principles related to defined boundaries and graduated sanctions exerted the strongest influence on the capacity of CBM to increase arapaima density. The degree to which most principles were present in all 83 communities was generally low, however, with the two most influential principles (defined boundaries and graduated sanctions) being the least present of all. Although the roles of the other principles (management rules, conflict resolution, collective action, and monitoring systems) are probably important, our results indicate that efforts aimed at strengthening the presence of defined boundaries and graduated sanctions in communities hold promise to improve the effectiveness of arapaima CBM regionally.
Community-based natural resource management (CBNRM) involves a system of local practices designed to regulate access to, and use of, natural resources through rules and norms shared by a set of ...users. These institutions are usually defined through rational motivations that drive collective action and well-delimited social and spatial boundaries. We discuss the shortcomings of these premises in dynamic ecological systems where the location of resource concentrations is ephemeral. We explore four cases of community-based management of river turtle nesting sites on the lower Amazon floodplain. Despite the high ecological risks, monitoring costs, and limited material benefits, community residents remain motivated to engage in this collective activity. Based on information from numerous studies carried out over a period of two decades, we discuss how motivation to develop CBNRMs has changed over time and space and how intercommunity linkages have contributed to the endurance of this local institution.
The contribution of working forests to tropical conservation and development depends upon the maintenance of ecological integrity under ongoing land use. Assessment of ecological integrity requires ...an understanding of the structure, composition, and function and major drivers that govern their variability. Working forests in tropical river floodplains provide many goods and services, yet the data on the ecological processes that sustain these services is scant. In flooded forests of riverside Amazonian communities, we established 46 0.1âha plots varying in flood duration, use by cattle and water buffalo, and time since agricultural abandonment (30â90 yr). We monitored three aspects of ecological integrity (stand structure, species composition, and dynamics of trees and seedlings) to evaluate the impacts of different trajectories of livestock activity (alleviation, stasis, and intensification) over nine years. Negative effects of livestock intensification were solely evident in the forest understory, and plots alleviated from past heavy disturbance increased in seedling density but had higher abundance of thorny species than plots maintaining low activity. Stand structure, dynamics, and tree species composition were strongly influenced by the natural pulse of seasonal floods, such that the defining characteristics of integrity were dependent upon flood duration (3â200 d). Forests with prolonged floods â¥140 d had not only lower species richness but also lower rates of recruitment and species turnover relative to forests with short floods <70 d. Overall, the combined effects of livestock intensification and prolonged flooding hindered forest regeneration, but overall forest integrity was largely related to the hydrological regime and age. Given this disjunction between factors mediating canopy and understory integrity, we present a subset of metrics for regeneration and recruitment to distinguish forest condition by livestock trajectory. Although our study design includes confounded factors that preclude a definitive assessment of the major drivers of ecological change, we provide muchâneeded data on the regrowth of a critical but poorly studied ecosystem. In addition to its emphasis on the dynamics of tropical wetland forests undergoing anthropogenic and environmental change, our case study is an important example for how to assess of ecological integrity in working forests of tropical ecosystems.
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