Sulfoxaflor is an insecticide belonging to the recent sulfoximine class, acting as a nicotinic acetylcholine receptor (nAChRs) agonist. There are few studies regarding sulfoxaflor's toxicity to ...non-target organisms. The present study aimed to investigate the acute and sub-lethal effects of sulfoxaflor on
by addressing survival, behaviour (feed intake and motricity), and neuromuscular, detoxification and oxidative stress, and energy metabolism biomarkers. Adult male green crabs were exposed to sulfoxaflor for 96 h and an LC
of 2.88 mg L
was estimated. All biomarker endpoints were sampled after three (T3) and seven (T7) days of exposure and behavioural endpoints were addressed at T3 and day six (T6). Sulfoxaflor affected the feed intake and motricity of
at T6. From the integrated analysis of endpoints, with the increase in concentrations of sulfoxaflor, after seven days, one can notice a lower detoxification capacity (lower GST), higher LPO levels and effects on behaviour (higher motricity effects and lower feed intake). This integrated approach proved to be valuable in understanding the negative impacts of sulfoxaflor on green crabs, while contributing to the knowledge of this pesticide toxicity to non-target coastal invertebrates.
O objetivo é pensar que a interculturalidade, enquanto mecanismo entre diferentes culturas, tornou-se uma perspectiva de se pensar a educação na sua globalidade. A perspectiva da interculturalidade ...contraria o discurso etnocêntrico, evidenciando as contradições nas práticas curriculares explícitas e implícitas, operando uma “rachadura” no sistema escolar e educacional, levando os/as profissionais que nele estão envolvidos/as a uma reflexão que propõe à necessidade de mudança e de desconstrução. Cabe-nos reconhecer que a complexidade dos enunciados denuncia a necessidade do enfrentamento das relações dominantes de poder na escola, visando torná-la um lugar de encontro, de aproximação e de articulação das diferenças, a partir da incorporação das relações interculturais e da promoção do diálogo entre os padrões culturais existentes e suas múltiplas significações. Torna-se um desafio à construção de uma nova relação com o currículo entendido como processo de construção social.
Tomando como inspiração a fala de professoras nas nossas ações de formação nas escolas, vamos problematizar, neste artigo, as potencialidades e os desafios presentes no trabalho com as relações de ...gênero e sexualidade na Educação Infantil. O nosso objetivo foi desenvolver reflexões sobre os sentidos e significados das ações de “ensinar”, “aprender” e “educar”, dentro de uma perspectiva de educação para as relações de gênero e sexualidade nas escolas. Para isso, nos baseamos nas abordagens teórico-metodológicas feministas, pós-estruturalistas e foucaultianas. Todas elas nos convidam a pensar os processos de constituição dos sujeitos, como resultado das relações saber-poder, incitando-nos a uma revisão de nossas práticas enquanto professoras e professores. Pudemos perceber a necessidade de uma compreensão mais ampla dos conceitos de gênero e sexualidade, bem como da articulação entre eles, o que facilitaria a eliminação de algumas barreiras para abordá-los sem medo.
ABSTRACT Galvanic vestibular stimulation (GVS) influences body balance and has proved to be useful to improve patients’ mood, quality of life, and cognitive skills. This study aimed to present three ...cases of patients with Parkinson’s disease and postural instability who had been submitted to GVS to improve their balance, by assessing the impact of this intervention on their cognition, mood, and quality of life. Patients were assessed before and after GVS sessions concerning P300 latency and scores on the 15-item Geriatric Depression Scale (GDS-15) and the 39-item quality-of-life Parkinson’s Disease Questionnaire (PDQ-39). The three patients’ P300 latency improved, possibly indicating improved attention. Their PDQ-39 score also improved, possibly indicating a positive impact on their quality of life. Their GDS-15 score did not change before and after the intervention. None of the patients had any intervention side effects. This three-case experimental pilot study has shown that GVS is a safe method, possibly useful to improve attention and, therefore, the quality of life of patients presented with Parkinson’s disease.
RESUMO A Estimulação Vestibular Galvânica (EVG) atua no equilíbrio corporal e tem se mostrado útil na melhora do humor, da qualidade de vida e de habilidades cognitivas. O objetivo deste estudo foi apresentar três casos de pacientes com doença de Parkinson e instabilidade postural que foram submetidos à EVG para melhorar o equilíbrio e avaliar o impacto dessa intervenção na cognição, no humor e na qualidade de vida. Os pacientes foram avaliados antes e após as sessões de EVG quanto a latência do potencial evocado P300, pontuação na escala de depressão geriátrica de 15 itens (EDG-15) e pelo questionário de qualidade de vida na doença de Parkinson de 39 itens (PDQ-39). Os três pacientes apresentaram melhora na latência do P300, indicando possível melhora na atenção. Apresentaram melhora na pontuação do PDQ-39, indicando possível impacto positivo na qualidade de vida. A pontuação na EDG-15 não modificou antes e após a intervenção. Nenhum paciente apresentou efeitos colaterais decorrentes da intervenção. Com base neste estudo piloto experimental de três casos, a EVG mostrou-se um método seguro e possivelmente útil para melhorar a atenção e, consequentemente, a qualidade de vida de pacientes com doença de Parkinson.
EDUCAÇÃO, SEXUALIDADES E RELAÇÕES DE GÊNERO Consolação, Davi Reis; Carneiro Araujo, Ludmilla; Silveira Meireles, Gabriela
Revista Diversidade & Educação.,
08/2023, Letnik:
11, Številka:
1
Journal Article
Recenzirano
Essa pesquisa tem como objetivo analisar o Instagram como um Artefato Cultural produtor de currículos que contribuem para a formação sobre as questões de gênero e sexualidades. Para tanto, foi ...realizada uma pesquisa qualitativa e análise de discurso na tentativa de analisar os discursos presentes em algumas postagens em perfis do Instagram que abordam as relações de gênero e sexualidade, bem como as interações de usuários, mapeando modos de pensar produzidos a partir do contato com as páginas. Conclui-se que o Instagram, como um artefato cultural, formativo e influenciador, está presente no cotidiano dos jovens e é capaz de, através dos perfis, postagens e interações, moldar os pensamentos e comportamentos dos usuários também no tema da sexualidade e dos gêneros, sendo capaz de produzir ações
Some dyes currently used by the textile, pharmaceutical, food, cosmetic, and photographic industries have been shown to be toxic and/or mutagenic to aquatic life. Most of these dyes resist ...degradation processes available for treating wastewater, and these processes might generate even more toxic by-products. Despite the large number of available dyes and the large quantity of dyes released into the environment, studies on their toxicity are still scarce. We evaluated and compared the effects in the animal model Danio rerio (zebrafish) of environmentally relevant concentrations of Disperse Red 60 (DR 60), 73 (DR 73), and 78 (DR 78) using the fish embryo acute toxicity (FET) test, morphometric analysis, immunofluorescence imaging, and behavioral parameters. DR 60 caused ocular modifications, while the DR 73 caused non-inflation of the swim bladder (NISB), pericardial edema (PE), scoliosis (S) and abnormal yolk sac (AYS) from at 0.125 mg/L. In behavioral tests, all the dyes induced changes in velocity and time spent swimming of exposed larvae. However, these alterations in behavior seem to be caused by different factors dependent on the dye and its concentration. Nevertheless, behavior seems to add valuable information concerning the hazards analysis of dyes, since it reveals to be the most sensitive group of parameters tested in the current study. In conclusion, of the behavioral and developmental alterations caused by these dyes should be interpreted as an alert for greater attention when registering new dyes and releasing them into the environment. In the particular case of DR 60 the possibility that directly affects the eye of larvae is of great environmental concern, but also from the human health perspective.
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•Exposure to DR 60 probably induces to zebrafish larvae blindness.•DR 73 alters cholinergic activity, energy allocated and development of zebrafish.•DR 78 alters the larvae of zebrafish behavior.
Anthropogenic noise is a growing threat to marine organisms, including fish. Yet very few studies have addressed the impact of anthropogenic noise on fish reproduction, especially in situ. In this ...study, we investigated the impacts of boat noise exposure in the reproductive success of wild Lusitanian toadfish (Halobatrachus didactylus), a species that relies on advertisement calls for mate attraction, using behavioural, physiological and reproductive endpoints. Two sets of artificial nests were deployed in the Tagus estuary and exposed to either ambient sound or boat noise during their breeding season. Toadfish males spontaneously used these nests to breed. We inspected nests for occupation and the presence of eggs in six spring low tides (in two years) and assessed male vocal activity and stress responses. Boat noise did not affect nest occupation by males but impacted reproductive success by decreasing the likelihood of receiving eggs, decreasing the number of live eggs and increasing the number of dead eggs, compared to control males. Treatment males also showed depressed vocal activity and slightly higher cortisol levels. The assessment of oxidative stress and energy metabolism-related biomarkers revealed no oxidative damage in noise exposed males despite having lower antioxidant responses and pointed towards a decrease in the activity levels of energy metabolism-related biomarkers. These results suggest that males exposed to boat noise depressed their metabolism and their activity (such as parental care and mate attraction) to cope with an acoustic stressor, consistent with a freezing defensive response/behaviour. Together, our study demonstrates that boat noise has severe impacts on reproductive fitness in Lusitanian toadfish. We argue that, at least fishes that cannot easily avoid noise sources due to their dependence on specific spawning sites, may incur in significant direct fitness costs due to chronic noise exposure.
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•The effect of boat noise on toadfish fitness was assessed in situ.•Chronic noise exposure impacted calling behaviour and reproductive success.•Biomarkers and cortisol levels point to stress induced freezing behaviour.
In recent years, the need for the development of alternative test methods for the conventional acute fish toxicity test (AFT) with adult fish has often been discussed. In addition, concerns have been ...raised on the potential risks related with environmentally realistic pesticide mixtures since risk evaluations have traditionally been based on individual pesticides. The insecticide/acaricide abamectin and the fungicide difenoconazole are the main pesticides that are intensively used in Brazilian strawberry crop and are hence likely to occur simultaneously in edge-of-field waterbodies. The aim of the present study was therefore to evaluate the lethal and sublethal toxicity of single and mixture exposures of these pesticides to zebrafish early life stages (embryos and juveniles). By comparing the derived toxicity data of the individual compounds with that previously determined for zebrafish adults, the order of life stage sensitivity was juvenile > adult > embryo. The pesticide mixture revealed a dose-level dependent deviation of the independent action model, with antagonism at low dose levels and synergism at high dose levels. Sublethal parameters (especially those related with locomotion) were considerably more sensitive than lethality. Subsequently, the inclusion of sublethal parameters may greatly improve the sensitivity of FET tests and hence its suitability as a substitution of adult fish testing in risk assessment evaluations.
•The order of zebrafish life stage sensitivity was juvenile > adult > embryo.•The mixture revealed antagonism at low dose levels and synergism at high dose levels.•Sublethal parameters (related with locomotion) are more sensitive than lethality.
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