Quantitative understanding of factors driving yield increases of major food crops is essential for effective prioritization of research and development. Yet previous estimates had limitations in ...distinguishing among contributing factors such as changing climate and new agronomic and genetic technologies. Here, we distinguished the separate contribution of these factors to yield advance using an extensive database collected from the largest irrigated maize-production domain in the world located in Nebraska (United States) during the 2005-to-2018 period. We found that 48% of the yield gain was associated with a decadal climate trend, 39% with agronomic improvements, and, by difference, only 13% with improvement in genetic yield potential. The fact that these findings were so different from most previous studies, which gave much-greater weight to genetic yield potential improvement, gives urgency to the need to reevaluate contributions to yield advances for all major food crops to help guide future investments in research and development to achieve sustainable global food security. If genetic progress in yield potential is also slowing in other environments and crops, future crop-yield gains will increasingly rely on improved agronomic practices.
Is soybean yield limited by nitrogen supply? Cafaro La Menza, Nicolas; Monzon, Juan Pablo; Specht, James E. ...
Field crops research,
November 2017, 2017-11-00, Letnik:
213
Journal Article
Recenzirano
Odprti dostop
•We developed a protocol to ensure ample N supply during the soybean crop season.•The protocol was applied to field experiments that covered a wide yield range.•Seed, protein, and oil yields were ...higher in crops grown with ample N supply.•Yield difference between N treatments increased with increasing yield potential.•Yield difference was related with greater biomass and seed number and weight.
As soybean yield continues to increase, it seems critical to know if there is a yield level at which potential contribution of indigenous nitrogen (N) sources (N fixation and soil mineralization) becomes insufficient to meet crop N requirements for high yields, while still maintaining or increasing protein and oil concentration. We have hypothesized that, in absence of other limiting factors, degree of N limitation increases with increasing yield potential (Yp) of the production environment. To test this hypothesis, we developed a novel protocol to ensure an ample N supply during the entire crop season (full-N treatment). That protocol was applied to field-grown irrigated soybean in Balcarce (Argentina) and Nebraska (USA), where measured full-N seed yields were ±15% of their simulated Yp in 92% of the cases. The combination of locations, years, sowing dates, and N treatments resulted in a wide range of seed yields, from 2.5 to 6.5Mgha−1. Overall, full-N seed yield averaged 11% higher than seed yield without N addition (zero-N). However, magnitude of yield difference between full-N and zero-N depended upon Yp, ranging from no detectable yield difference in low-Yp (ca. 2.5Mgha−1) to up to 900kgha−1 in high-Yp environments (ca. 6Mgha−1). Seed yield differences were associated with higher aboveground dry matter, seed number, and seed weight in the full-N versus zero-N treatments. Seed protein (but not oil) concentration was higher in the full-N treatment, and both protein and oil yields were higher in the full-N versus zero-N treatments. Findings from this study indicate that (i) N limits soybean seed yield (as well as protein yield, and oil yield) in environments with high Yp, where indigenous N sources seem insufficient to fully satisfy crop N requirements, and (ii) yield response to N fertilizer can occur above a 2.5Mgha−1 Yp threshold and has an upper limit of 250kg seed per Mg increase in Yp.
•Cropping systems are selected prior sowing any crop and have huge impact on them.•Little is known about how cropping system decision impacts on crop yield gaps (Yg).•Cropping system-imposed yield ...gap (CSIYg) helped to explain soybean Yg causes.•Water limitation was higher in single than double-cropped soybean.•Double-cropped soybean is a competitive alternative for increasing grain production.
Favorable weather conditions prevailing on most South American Pampas allows to grow more than one crop per year. Indeed, increasing crop intensity per unit area has been highlighted as an opportunity to increase crop production in a high food demanding world scenario. Previous studies have analyzed cropping-system yield gap by aggregating crop yields either as total amount of grain or as unit of energy. However, few cropping-system yield gap analysis have made a distinction between single (i.e., soybean sown as a single crop per year) and double-cropped soybean (i.e., soybean sown immediately after harvest of a winter cereal crop), and none of them at a country level. This article focuses on the estimation of cropping system-imposed yield gap (CSIYg), which is defined as the difference of seed yield between single soybean and double-cropped soybean. The aims of the present study were: (i) to analyze yield potential (Yp), water-limited (Yw) and yield gap (Yg) spatial and interannual variability; (ii) to investigate the concept of CSIYg for soybean using cropping systems in Uruguay as a proof of concept; and (iii) to assess differences on yield variability between single and double-cropped soybean. Yp and Yw were estimated for single and double-cropped soybean in specific locations within the major soybean crop producing areas using CROPGROW model coupled with long-term good quality weather data, soil types and dominant management practices. Estimations were scaled up following the protocols of the Global Yield Gap Atlas project. We applied a boundary function analysis to assess the differences on Yw variability between single and double-cropped soybean. At country level Yp was estimated on 6.6 and 5.7 Mg ha−1 for single and double-cropped soybean, respectively. However, we found lower differences on Yw between single and double-cropped soybean (3.6 and 3.4 Mg ha−1, respectively). We estimated CSIYg due to combined effect of weather condition and water regime on 3.2 Mg ha−1. The CSIYg representing the combined effect of weather condition, water regime and management was estimated on 1.6 Mg ha−1. Double-cropped and single soybean showed the same Yw response to precipitations and a similar Yw variability (t-test P = 0.55). Our results highlight double-cropped soybean cropping systems as an alternative for increasing grain production in this main agricultural region of the world.
•Argentina has potential to increase crop production with substantial impact at a global scale.•Current yield gap represents 41% (wheat and maize) and 32% (soybean) of water-limited yield ...potential.•Yield gap variations across regions can be related to crop history.•Magnitude of yield gaps depended upon year, with larger gaps in favorable wet years.
Favorable climate and soils for rainfed crop production, together with a relatively low population density, results in 70–90% of Argentina grain production being exported. No assessment to date has tried to estimate the potential for extra grain production for soybean, wheat and maize, which account for 78% of total harvested area, by yield gap closure on existing cropland area and its impact at a global scale. The objectives of this paper are (i) to estimate how much additional grain could be produced without expanding crop area by closing yield gaps in Argentina, (ii) to investigate how this production and yield gaps varies across regions and years, and (iii) to analyze how these inter-annual variations are related to El Niño—Southern Oscillation phenomenon (ENSO). Production increase on existing crop area was assessed for soybean, wheat and maize by quantifying the yield gap (Yg), that is, the difference between water-limited yield potential (Yw) and actual yield (Ya). A bottom-up approach was followed to estimate Yw and Yg, in which these parameters were first estimated for specific locations in major crop producing areas and subsequently up-scaled to country level based on spatial distribution of crop area and climate zones. Locally-calibrated crop simulation models were used to estimate Yw at each selected location based on long-term weather data and dominant soil types and management practices. For the analyzed period, the national level Yg represented 41% of Yw for both wheat and maize and 32% of the Yw for soybean. If farmers had closed Yg from these levels to 20% of Yw, Argentina could have increased soybean, wheat and maize production by a respective 7.4, 5.2, and 9.2Mt, without expanding cropland area. This additional production would have represented an increase of 9%, 4%, and 9% of soybean, wheat, and maize global exports. This potential grain surplus was, however, highly variable because of the ENSO phenomenon: attainable soybean production was 12Mt higher in favorable “El Niño” years compared with unfavorable “La Niña” years. Interestingly, Yg tended to be higher in wet years, suggesting that farmers do not take full advantage of years with favorable conditions for rainfed crop production. Regional variation in Yg was found in Argentina highlighting the usefulness of this work as a framework to target research and, ultimately, reduce gaps in areas where current yields are well below their potential.
Background and Aims
G protein–coupled receptor (GPR) 55 is a putative cannabinoid receptor, and l‐α‐lysophosphatidylinositol (LPI) is its only known endogenous ligand. Although GPR55 has been linked ...to energy homeostasis in different organs, its specific role in lipid metabolism in the liver and its contribution to the pathophysiology of nonalcoholic fatty liver disease (NAFLD) remains unknown.
Approach and Results
We measured (1) GPR55 expression in the liver of patients with NAFLD compared with individuals without obesity and without liver disease, as well as animal models with steatosis and nonalcoholic steatohepatitis (NASH), and (2) the effects of LPI and genetic disruption of GPR55 in mice, human hepatocytes, and human hepatic stellate cells. Notably, we found that circulating LPI and liver expression of GPR55 were up‐regulated in patients with NASH. LPI induced adenosine monophosphate–activated protein kinase activation of acetyl–coenzyme A carboxylase (ACC) and increased lipid content in human hepatocytes and in the liver of treated mice by inducing de novo lipogenesis and decreasing β‐oxidation. The inhibition of GPR55 and ACCα blocked the effects of LPI, and the in vivo knockdown of GPR55 was sufficient to improve liver damage in mice fed a high‐fat diet and in mice fed a methionine‐choline–deficient diet. Finally, LPI promoted the initiation of hepatic stellate cell activation by stimulating GPR55 and activation of ACC.
Conclusions
The LPI/GPR55 system plays a role in the development of NAFLD and NASH by activating ACC.
Nitrogen (N) supply can limit the yields of soybean Glycine max (L.) Merr. in highly productive environments. To explore the physiological mechanisms underlying this limitation, seasonal changes in N ...dynamics, aboveground dry matter (ADM) accumulation, leaf area index (LAI) and fraction of absorbed radiation (fAPAR) were compared in crops relying only on biological N2 fixation and available soil N (zero‐N treatment) versus crops receiving N fertilizer (full‐N treatment). Experiments were conducted in seven high‐yield environments without water limitation, where crops received optimal management. In the zero‐N treatment, biological N2 fixation was not sufficient to meet the N demand of the growing crop from early in the season up to beginning of seed filling. As a result, crop LAI, growth, N accumulation, radiation‐use efficiency and fAPAR were consistently higher in the full‐N than in the zero‐N treatment, leading to improved seed set and yield. Similarly, plants in the full‐N treatment had heavier seeds with higher N concentration because of greater N mobilization from vegetative organs to seeds. Future yield gains in high‐yield soybean production systems will require an increase in biological N2 fixation, greater supply of N from soil or fertilizer, or alleviation of the trade‐off between these two sources of N in order to meet the plant demand.
Symbiotic nitrogen (N) fixation does not preclude N limitation in soybean grown in highly productive environments. Insufficient N supply contrains crop growth and N mobilization to the seeds. Future yield gains in high‐yield soybean production systems will require an increase in biological N2 fixation, greater supply of N from soil or fertilizer, or alleviation of the trade‐off between these two sources of N in order to meet the plant demand.
•We used two independent approaches to identify the beginning and end of the critical period for seed number determination in soybean.•Critical period for seed number determination occurs during the ...R3-R6 phase.•Seed number was related to biomass accumulation during the critical period.•Accumulated biomass is a better predictor of seed number than crop growth rate or duration alone.
Seed number (SN) is positively associated with aboveground dry matter (ADM) accumulation in most crop species. In soybean, there are discrepancies among studies relative to the start and end of the critical period for seed number determination. The objective of this study was to more precisely identify those two stages. To do so, we followed two approaches: (i) analyses of experimental data where differences in SN occurred as a result of variation in crop growth due to weather and management practices and (ii) review of published experiments where soybean was subjected to artificial stresses during specific crop phases. Following the first approach, we analyzed the relationships between SN versus ADM accumulation and its components, crop growth rate (CGR) and duration, for different reproductive phases using data from experiments that portrayed a wide range of environments and management practices. In the second approach, we compared SN values in stressed versus non-stressed treatments. Accumulated ADM during the R3 to R6 phase explained ca. 70 % of the variation in SN across experiments. The CGR during R3-R6 was also a good predictor of SN, but it had lower explanatory power compared with accumulated ADM, because CGR did not account for changes in duration of critical period across experiments. Review of published data, wherein soybean crops were subjected to artificial stresses during different reproductive phases, confirmed that the R3-R6 phase is a critical phase for SN determination in soybean. Key findings of this study were: (i) critical period for SN determination in soybean occurs during the R3-R6 phase and (ii) accumulated ADM during the critical period is a better predictor of SN compared with CGR because it accounts for differences in the duration of the critical period as a result of weather and management.
•Nitrogen (N) accumulation and use efficiency were assessed in high-yield soybean.•We compared a zero N versus a full N treatment that received ample N supply.•Yield increase in the full N treatment ...was explained by greater accumulated N.•There were no changes in N-use efficiency and/or N-harvest index between treatments.•Magnitude of N limitation was modulated by indigenous soil N supply.
Recent reviews about soybean nitrogen (N) requirement have speculated about a possible N limitation in high-yield environments (>4.5 Mg ha−1). However, these studies did not provide definitive experimental data to test that hypothesis and results from the literature are conflicting. To fill this knowledge gap, we evaluated N limitation across 13 high-yield soybean environments in Argentina and USA. Each experiment included a ‘zero-N’ treatment, which forced the crop to rely on biological N2 fixation and indigenous soil N, and a ‘full-N’ treatment, which provided an ample fertilizer N supply during the entire crop cycle based on site-specific yield potential. Accumulated N in aboveground dry matter (ADM) measured in a N-omission maize plot grown adjacent to the soybean experiments was used to determine indigenous soil N supply. Soybean seed yield, protein and oil concentration, ADM, harvest index (HI), accumulated N in ADM, N harvest index (NHI), and seed N were measured in both treatments at physiological maturity. A simple conceptual framework relating ADM with accumulated N was used to assess treatment differences in ADM, accumulated N, and N-use efficiency (NUE). To account for treatment differences in seed biomass composition, mass-based ADM was expressed in glucose equivalents (ADMe). Seed yield ranged from 4.6 to 6.7 Mg ha−1 (full-N) and 4 to 5.8 Mg ha−1 (zero-N), with the full-N treatment averaging 12% (0.6 Mg ha−1) and 3% (9 g kg−1) higher seed yield and protein concentration, respectively. The full-N treatment exhibited 18% (70 kg N ha−1) and 14% (1.6 Mg ha−1) greater accumulated N and ADM, respectively, compared with the zero N treatment, without changes in HI and NHI, but slightly lower NUE (29 versus 30 kg ADM kg−1 N in full and zero-N, respectively). However, NUE differences between treatments became indistinguishable when ADM was expressed as ADMe (45 kg glucose kg−1 N). The (full-N minus zero-N) seed yield difference and the indigenous soil N supply were negatively associated. This research documented (i) the existence of N limitation in high-yield soybean, (ii) that seed yield and protein concentration increases were physiologically associated with changes in accumulated N (but not in NUE and/or NHI), and (iii) that the degree of N limitation is modulated by indigenous soil N supply. Findings from this study can serve as a basis to identify environments with the largest N limitation and thus guide N management in soybean.
Purpose
To determine the risk factors associated with major complications in patients with histologically confirmed Xanthogranulomatous pyelonephritis (XGP) who underwent nephrectomy.
Methods
A ...multicenter retrospective study was performed including patients who underwent nephrectomy between 2018 and 2022 with histopathological diagnosis of XGP. Clinical and laboratory parameters at the initial presentation were evaluated. Data on extension of XGP was recorded as per the Malek clinical-radiological classification. Characteristics of nephrectomy and perioperative outcomes were obtained. The primary outcome was major complications, defined as a CD ≥ grade 3 and the need for intensive care unit (ICU) admission. Secondary outcomes included the comparison of complications evaluating the nephrectomy approach (transperitoneal, retroperitoneal, and laparoscopic). A sub-analysis stratifying patients who needed ICU admission and Malek classification was performed.
Results
A total of 403 patients from 10 centers were included. Major complications were reported in 98 cases (24.3%), and organ injuries were reported in 58 patients (14.4%), being vascular injuries the most frequent (6.2%). Mortality was reported in 5 cases (1.2%). A quick Sepsis-related Organ Failure Assessment (qSOFA) score ≥ 2, increased creatinine, paranephric extension of disease (Malek stage 3), a positive urine culture, and retroperitoneal approach were independent factors associated with major complications.
Conclusion
Counseling patients on factors associated with higher surgical complications is quintessential when managing this disease. Clinical-radiological staging, such as the Malek classification may predict the risk of major complications in patients with XGP who will undergo nephrectomy. A transperitoneal open approach may be the next best option when laparoscopic approach is not feasible.
Xanthogranulomatous pyelonephritis (XGP) is an uncommon chronic granulomatous infection of renal parenchyma. XGP is often associated with long-term urinary tract obstruction due to stones and ...infection. We aimed to analyze the clinical, laboratory, and microbial culture profiles from bladder and kidney urine of patients who were diagnosed with XGP. Databases of patients with histopathological diagnosis of XGP from 10 centers across 5 countries were retrospectively reviewed between 2018 and 2022. Patients with incomplete medical records were excluded. A total of 365 patients were included. There were 228 (62.5%) women. The mean age was 45 ± 14.4 years. The most common comorbidity was chronic kidney disease (71%). Multiple stones were present in 34.5% of cases. Bladder urine culture results were positive in 53.2% of cases. Kidney urine culture was positive in 81.9% of patients. Sepsis and septic shock were present in 13.4% and 6.6% of patients, respectively. Three deaths were reported.
was the most common isolated pathogen in both urine (28.4%) and kidney cultures (42.4%), followed by
in bladder urine cultures (6.3%) and
(7.6%) in kidney cultures. Extended-spectrum beta-lactamases producing bacteria were reported in 6% of the bladder urine cultures. On multivariable analysis, urosepsis, recurrent urinary tract infections, increased creatinine, and disease extension to perirenal and pararenal space were independent factors associated with positive bladder urine cultures. On multivariable analysis, only the presence of anemia was significantly more frequent in patients with positive kidney cultures. Our results can help urologists counsel XGP patients undergoing nephrectomy.
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