The preparation, chemical properties and bio-activities of polysaccharides derived from halophytes have gained an increasing interest in the past few years. Phytochemical and pharmacological reports ...have shown that carbohydrates are important biologically active compounds of halophytes with numerous biological potentials. It is believed that the mechanisms involved in these bio-activities are due to the modulation of immune system. The main objective of this summary is to appraise available literature of a comparative study on the extraction, structural characterizations and biological potentials, particularly immunomodulatory effects, of carbohydrates isolated from halophytes (10 families). This review also attempts to discuss on bioactivities of polysaccharides related with their structure-activity relationship. Data indicated that the highest polysaccharides yield of around 35% was obtained under microwave irradiation. Structurally, results revealed that the most of extracted carbohydrates are pectic polysaccharides which mainly composed of arabinose (from 0.9 to 72%), accompanied by other monosaccharides (galactose, glucose, rhamnose, mannose and xylose), significant amounts of uronic acids (from 18.9 to 90.1%) and some proportions of fucose (from 0.2 to 8.3%). The molecular mass of these pectic polysaccharides was varied from 10 to 2650 kDa. Hence, the evaluation of these polysaccharides offers a great opportunity to discover novel therapeutic agents that presented especially beneficial immunomodulatory properties. Moreover, reports indicated that uronic acids, molecular weights, as well as the presence of sulfate and unmethylated acidic groups may play a significant role in biological activities of carbohydrates from halophyte species.
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•Polysaccharides from halophytes presented potent structural and biological feature.•Polysaccharides (PS) from different species of halophytes were firstly compared.•MAE extraction of PS from halophytes provides the higher extraction yield.•The most of PS from selected halophytes are mainly pectic polysaccharides.•Polysaccharides from halophytes possess promising immunomodulatory properties.
Introductionles stomies digestives constituent l´aboutissement d´un certain nombre d´interventions chirurgicales. Elles peuvent être temporaires ou définitives. Le patient porteur de stomie se trouve ...confronté à des aléas d´ordre physique et psychologique. Il nécessite donc une adaptation aux changements et une acceptation de la situation qu´elle soit temporaire ou définitive. Le but de ce travail est d´évaluer l´impact des stomies digestives sur la qualité de vie des patients et leur retentissement professionnel.Méthodesil s´agit d´une étude rétrospective, menée de janvier 2010 à décembre 2014. Au cours de cette période 115 patients avaient eu des stomies digestives. Parmi ces patients, soixante étaient en âge d´activité professionnelle, avaient un emploi fixe et avaient repris leurs travail; ils constituent l´effectif de notre étude. Le recueil des données était réalisé par un questionnaire spécifique: le questionnaire généraliste SF-36 réalisé en post opératoire.Résultatsle score moyen pour la qualité de vie globale pour les patients stomisés était 41. Quarante patients avaient une mauvaise qualité de vie avec un score SF-36 qui était inférieur à 50. Notre étude a démontré que les patients stomisés ont éprouvé des difficultés de fonctionnement dans des situations de travail. Quarante-huit patients décrivaient une gêne directement liée à la stomie lors de l´exercice de leurs activités professionnelles. Les causes évoquées étaient d´ordre physique dans 6 cas et d´ordre psychologique dans 3 cas. Six patients étaient mutés vers des postes plus adaptés à leur situation.Conclusionl´objectif de la prise en charge des patients porteurs de stomie digestive doit être la réintégration sociale et professionnelle adéquate. Ceci ne peut se concevoir qu´en impliquant le médecin de travail, le psychologue, le stomathérapeute et les associations dans cette prise en charge.
is one of the most widespread curative plants in the world, being vastly cultivated in arid and semi-arid regions as one of the oldest spice plants. The present study explored the extraction of ...polysaccharides from Coriandrum sativum seeds and the evaluation of their antioxidant potential and hepatoprotective effects in vivo. The polysaccharide from coriander seeds was extracted, and the structural characterization was performed by FT-IR, UV-vis, DSC, NMR (1D and 2D), GC-MS, and SEC analysis. The polysaccharide extracted from
(CPS) seeds was characterized to evaluate its antioxidant and hepatoprotective capacities in rats. Results showed that CPS was composed of arabinose, rhamnose, xylose, mannose, fructose, galactose, and glucose in molar percentages of 6.2%, 3.6%, 8.8%, 17.7%, 5.2%, 32.9%, and 25.6%, respectively. Further, CPS significantly hindered cadmium-induced oxidation damage and exercised a protective effect against Cd hepatocytotoxicity, with a considerable reduction in MDA production and interesting CAT and SOD enzyme levels. Results suggest that CPS might be employed as a natural antioxidant source.
The goal of this work was to investigate the impact of the flavoring of some aromatic plants/spices, including rosemary (R), lemon (L) and orange (O) at the concentration of 5% and 35% (
/
) added by ...2 methods (conventional maceration and direct flavoring), on quality attributes, chemical changes and oxidative stability of extra virgin olive oil (EVOO). Six flavored oils were obtained (EVOO + O, O + O, EVOO + R, O + R, EVOO + L and O + L). The physicochemical parameters (water content, refractive index, acidity and peroxide value, extinction coefficient, fatty acids, volatile aroma profiles, Rancimat test, phenols and pigments composition) of the flavored oils were investigated. Based on the results obtained, it was observed that flavoring with a conventional process provided increased oxidative stability to the flavored oils, especially with rosemary (19.38 ± 0.26 h), compared to that of unflavored oil. The volatile profiles of the different flavored oils revealed the presence of 34 compounds with the dominance of Limonene. The fatty acid composition showed an abundance of mono-unsaturated fatty acids followed by poly-unsaturated ones. Moreover, a high antioxidant activity, a significant peripheral analgesic effect (77.7% of writhing inhibition) and an interesting gastroprotective action (96.59% of ulcer inhibition) have been observed for the rosemary-flavored oil. Indeed, the flavored olive oils of this study could be used as new functional foods, leading to new customers and further markets.
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•UAE of antioxidant pectic-polysaccharide yield from S. fruticosa was optimized.•BBD was suitably used to optimize the extraction conditions (YSFP and YTAC).•Optimal conditions for ...pectin extraction at pH = 2.9 was 90 °C for 37 min.•Physical and Chemical characterizations were investigated.•Extracted carbohydrates presented significant pharmacological activities.
Box-Behnken design (BBD) was performed via ultrasound-assisted system to optimize extraction yield and total antioxidant ability of polysaccharides from Suaeda fruticosa. Three independent variables were studied: temperature, time and pH with optimal settings 90 °C, 37 min and 2.9, respectively. Under these settings, isolation yield and total antioxidant activity were 34.0% and 31.8 mg ascorbic acid equivalent/g material, respectively. Furthermore, preliminary structure study was carried out using UV–vis analysis, Fourier transform infrared spectroscopy (FT-IR) and Nuclear magnetic resonance (1D (1H, 13C NMR) and 2D (1H, 1H COSY, 1H/13C HSQC)) methods Size exclusion chromatography (SEC) determination revealed that polysaccharide extracted had an average molecular weight of 240 kDa. Chemical composition analyses showed that extracted polysaccharide was a pectin-like polysaccharide with uronic acid content (47.5%) and neutral monosaccharides (52.5%) constituted mainly of arabinose, mannose, galactose, rhamnose, glucose and xylose in the molar percentage of 48.63%, 5.85%, 29.42%, 7.96%, 6.54% and 1.60%, respectively. This sugar composition was typical of that of a galactoarabinan. Importantly, the optimum polysaccharide possesses significant potentials in antioxidant activity effect. Moreover, pharmacological investigation of extracted polysaccharide revealed a good anti-inflammatory effect and interesting peripheral as well as central antinociceptive activities.
Koch’s bacillus infection is a rare cause of gastric ulcer. Gastric perforation associated with tuberculosis is extremely rarely presented as generalised peritonitis. A 39-year-old patient presented ...with epigastralgia with fever for one week. The physical examination found a generalised abdominal defense. Computed tomography evoked the diagnosis of perforated duodenal ulcer. The patient was operated and a suture excision of a perforated gastric ulcer was performed. The mesentery contained multiple lymph nodes. The small intestine was uniformly carded. The histopathological examination showed a gastric tuberculous ulcer. Acute peritonititis complicating tuberculous duodenal ulcer should be evoked especially in endemic area. Clinical history, abdominal CT scan results, and intraoperative exploration should suggest this diagnosis with therapeutic implications.
The anatomical variants of the posterior right sectoral duct of the biliary tract are frequent. They have a surgical importance involvement. We report a case of 63-year-old female patient operated by ...laparoscopy for acute cholecystitis with an intraoperative cholangiography discovery of an insertion of the posterior right sectoral duct on the bile duct below the cystic duct. The insertion of the posterior segmental canal on the bile duct could represent type A6 of the Huang classification. This biliary variation should be known to avoid posterior segmental canal injury, during cholecystectomy.
Le prolapsus rectal est un trouble de la statique du rectum, qui réalise une invagination de la paroi rectale aboutissant à son extériorisation à travers l’anus. Il touche généralement l’enfant et le ...sujet âgé. Sa survenue chez l’adulte jeune est rare. L’étranglement du rectum prolabé est également une complication rare. Nous rapportons l’observation d’un jeune de 30 ans, opéré en urgence pour un prolapsus rectal étranglé. Il a eu une recto-sigmoïdectomie périnéale (intervention d’Altemeier) en urgence avec des suites simples.
La hernie post-traumatique de la paroi abdominale antérieure peut être méconnue dans un contexte d’urgence. Nous rapportons l’observation d’un patient âgé de 32 ans, avec un BMI à 30 Kg/m2 ayant ...présenté une hernie de la paroi abdominale antérieure suite à un accident de la voie publique. Cette lésion était méconnue par l’examen clinique. La tomodensitométrie abdominale montrait un défect de 8 cm de la paroi abdominale antérieure. Le patient était opéré avec découverte d’un défect musculo-aponévrotique sur 12 cm. La réparation était réalisée par une suture par des points séparés. Les suites opératoires étaient marquées par une nécrose secondairement infectée de la peau. Elle avait bien évolué après cicatrisation dirigée. A 3 mois post-opératoire, le patient va bien avec une plaie cicatrisée et une paroi abdominale solide.
La découverte de tumeurs primitives synchrones à un cancer colorectal a fait l’objet de plusieurs publications. Cette association peut survenir de manière sporadique ou rentrer dans le cadre de ...syndromes cliniques bien définis tel que le syndrome de Lynch. L’association synchrone d’un cancer colorectal (CCR) et d’un carcinome à cellules rénales est rare. Elle est encore plus rare lorsque le carcinome à cellules rénales est de sous-type papillaire avec seulement 2 cas rapportés dans la littérature. L’association CCR et rénaux ne semble pas être liée à une anomalie des protéines du système MMR (MisMatch Repair) et n’intègre à ce jour aucun syndrome clinique. Nous rapportons le cas d’une femme âgée de 69 ans qui a simultanément présenté un adénocarcinome colique et un carcinome papillaire du rein de type 1, de découverte fortuite au cours du bilan d’extension du CCR. Nous discuterons la pathogénie ainsi que le pronostic de cette entité rarement décrite.
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