Optic nerve gliomas were diagnosed with computed tomography (CT) in 10 children. CT: (A) provides the best radiographic means of demonstrating the orbital portion of the optic nerves; (b) can ...evaluate the clinically unsuspected optic nerve for bilateral gliomas; (c) demonstrates gross intracranial involvement; and (d) can be used to follow the course of a glioma. Gliomas can present on CT as (a) a uniform thickening of the entire nerve; (b) a solitary fusiform enlargement of the nerve; or (c) an irregular solid thickening along the nerve. The authors routinely use axial CT of optic nerves as the primary diagnostic scan.
The advent of scanners with an air gap and a tilting gantry have made possible the use of the coronal view in computed tomography of the skull and brain in infants and children. Of 400 axial scans ...performed over a four-month period, 50 were supplemented by the coronal projection. Although the artifacts, uncomfortable position, and prolonged scanning time associated with coronal scanning make it impractical as the only modality, when used as an adjunct to the axial view it can provide valuable additional diagnostic information.
It is occasionally necessary in evaluating lesions around the third ventricle and posterior fossa to supplement the axial view with another projection. The authors have routinely used the coronal ...projection as a second projection. However, the Towne view for computed tomography can be used as a second projection instead of the coronal; it is technically easier and faster to perform than the coronal projection, and provided good evaluation of the posterior fossa and para third ventricular areas in children.
Coronal computed tomography is an important adjunct to the routine axial view in the evaluation of lesions of the skull and brain in infants and children. Of 400 axial scans performed over a ...four-mounth period, 50 were supplemented by coronal scans. Intracranial or cranial abnormalities were present in 39 (78%). Although the disadvantages of the coronal projection make it impractical as the only modality, when used as an adjunct to the axial view certain lesions of the skull and brain are diagnosed and delineated better.
CT-2 mouse monoclonal antibody to the E-rosette receptor was used with complement to deplete bone marrow of E-rosette-positive cells (T cells). Depletion of E-rosette-positive cells was complete and ...nontoxic to hematopoietic progenitor cells. Depletion of E-rosette-positive cells with CT-2 may decrease the severity of graft-versus-host disease following bone marrow transplantation and extend the application of bone marrow transplantation to those without HLA-identical donors.
