Upon the first publication of the fifth iteration of the Functional Annotation of Mammalian Genomes collaborative project, FANTOM5, we gathered a series of primary data and database systems into the ...FANTOM web resource (http://fantom.gsc.riken.jp) to facilitate researchers to explore transcriptional regulation and cellular states. In the course of the collaboration, primary data and analysis results have been expanded, and functionalities of the database systems enhanced. We believe that our data and web systems are invaluable resources, and we think the scientific community will benefit for this recent update to deepen their understanding of mammalian cellular organization. We introduce the contents of FANTOM5 here, report recent updates in the web resource and provide future perspectives.
Upon the first publication of the fifth iteration of the Functional Annotation of Mammalian Genomes collaborative project, FANTOM5, we gathered a series of primary data and database systems into the ...FANTOM web resource (http://fantom.gsc.riken.jp) to facilitate researchers to explore transcriptional regulation and cellular states. In the course of the collaboration, primary data and analysis results have been expanded, and functionalities of the database systems enhanced. We believe that our data and web systems are invaluable resources, and we think the scientific community will benefit for this recent update to deepen their understanding of mammalian cellular organization. We introduce the contents of FANTOM5 here, report recent updates in the web resource and provide future perspectives.
Eighty-six patients with primary nephrotic syndrome in our clinic were classified according to Burch's classification, and the relationship swas studied between histological changes and therapeutic ...effects with steroid.1) In forty-one cases (47.7%), the biopsies of the kidney revealed the minimal histopathological change. The averaged age of the onset was 24.1 years of age in this group.2) In the patients responded to steroid therapy, the proteinuria, hypoproteinemia and hypercholesterolemia were improved or normalized in this order. These laboratory data were improved or normalized more rapidly in the minimal change group than in the other groups.3) Complete remission of the minimal change group by steroid therapy was obtained in twenty-nine of thirty-nine cases (74.4%) within half a year and in twenty-one of twenty-twenty-five cases (84%) after two years.
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