The paper provides representative data on the indices of lipid metabolism and the activity of cardiospecific (lactate dehydrogenase--LDH, creatine phosphokinase--CPK) in patients with diabetes ...mellitus, Type I and II, (male inhabitants of Kaunas aged 40 to 59) which were compared with similar data on control persons randomly selected from the population during epidemiological surveys. They covered 85.3% of all detected and followed-up patients of this age with diabetes mellitus. Total and HDL cholesterol and triglycerides were determined by the enzymatic methods, LDH by the spectrophotometric method and CPK by the fluorometric method. It was shown that patients with Type II diabetes mellitus (insulin-independent) in addition to a raised concentration of glucose on an empty stomach were characterized by an increase in the level of cholesterol up to 6.34-0.51 mmol/l and especially triglycerides up to 5.98-1.78 mmol/l as compared to the control values (5.39-0.11 and 1.48-0.12 mmol, respectively). The concentration of HDL cholesterol and CPK and LDH activity in the patients did not differ from the control level.
The average concentration of malondialdehyde (MDA) in diabetes mellitus males was not higher than in the age-matched controls whereas alpha-tocopherol levels in diabetes mellitus significantly ...exceeded the normal disregarding the pattern of the disease and closely correlated with the concentration of triglycerides. Lower concentration of retinol in comparison with the control group was observed in the patients. Relative levels of alpha-tocopherol/MDA and retinol/MDA were age-dependent: in patients under 30 and above 50 the levels of alpha-tocopherol/MDA were significantly higher than in their normal age-matches while in 31-50-old ones no elevation in the above mentioned levels was observed. Retinol/MDA levels were significantly lower in the latter age group. The data are indicative of decreased levels of alpha-tocopherol and retinol in diabetes mellitus patients aged 31-50.
Certain conditions like drug use, diet, physical activity, etc., must be adhered to while running the glucose tolerance test. The Second WHO Expert Committee on Diabetes Mellitus (1979) suggested ...that the oral glucose tolerance test should be carried out with 75 g of glucose (for children 1.75 g/kg of ideal body mass but not over 75 g). During epidemiological investigations a glucose solution should be prepared by a constant concentration method using an areometer. Schematic interpretation expressed in the rectangular coordinate system reflecting diagnosis was offered for the estimation of findings.
'The revolutions of 1989' remains the standard term used to describe the onset of post-commununist transformations more than thirty years ago. Zenonas Norkus proposes a completely new perspective, ...theorising them as the next wave of modern social restorations, starting with the post-Napoleonic restorations in 1815.
The Programme on Diabetes Mellitus Control is a constituent part of Integrated Programme on Chronic Non-infectious Diseases Control. The epidemiological evidence has demonstrated the high prevalence ...of deranged carbohydrate metabolism in the republic. Registers of carbohydrate metabolism disorders were created for the children's population of the Republic and the adult population of Kaunas and two agricultural-industrial regions. A school for diabetic patients and the society 'Insula' were organised. The research-practical programme is implemented in stages.
