Oral Diseases (2012) 18, 389–395
Objective: The aim of the study was to examine whether the MBL2 C(‐290)G and G161A, MASP2 A359G, AMELX C287T and C522T, and ENAM C2452T polymorphisms are associated ...with dental caries.
Subjects and methods: Genomic DNA of 95 Polish children with ‘higher caries experience’ (HC) and 84 subjects with ‘lower caries experience’ (LC) belonging to two age‐groups (5 and 13 years old) was extracted from the buccal mucosa. SNPs were genotyped with PCR‐RFLP methods.
Results: Among 5‐year‐old children, we found significantly higher percentage of subjects carrying MBL2 (‐290)G allele in HC group compared with LC group (43.2%vs 17.6%, P = 0.023). MBL2 C(‐290)G–G161A C–G haplotype was overrepresented in LC group in 5‐year‐olds (P = 0.01), while the opposite association was observed in 13‐year‐olds, where C–G was overrepresented in HC group (P = 0.028). In 5‐year‐old children, the frequency of MBL2 G–G haplotype was higher in HC group compared with LC subjects (P = 0.045), while the opposite association (with borderline significance) was observed in 13‐year‐old children (P = 0.057). SNPs in MASP2, AMELX, and ENAM were not associated with dental caries.
Conclusion: MBL2 gene polymorphism is associated with caries experience in Polish children, but the direction of this association seems to be opposite in primary and permanent dentition.
(1) Background: In Italy, about one fourth of all schoolchildren experience a trauma to the permanent dentition. Management of avulsion trauma is challenging and requires adherence to clinical ...protocols. The aim of this study was to investigate the management knowledge of avulsed teeth among Italian dentists and to promote the guidelines' dissemination through the use of new social media. (2) Methods: The survey was carried out during the COVID-19 lockdown in Italy (March-May 2020). The questionnaire was sent anonymously to a total of 600 dentists. The questionnaire consisted of two parts. Part A-demographic and professional data and Part B-management of traumatic avulsion. (3) Results: The response rate was 50.6% and the mean fraction of correct responses was 0.524. Issues related to the therapeutic management of avulsed teeth were shown to be not well understood by the respondents. Professionals with qualifications in dentistry and those who declared to know the guidelines responded better, while other demographic and professional factors were insignificant. (4) Conclusions: Italian dentists' knowledge of the management of avulsion trauma should be improved. Educational programs and campaigns must be undertaken to improve their awareness and adherence to the Italian and international guidelines.
To assess the prevalence of sella turcica anomalies on lateral cephalograms of children with malocclusion. To describe the craniofacial morphology in patients with sella turcica anomalies.
Lateral ...cephalograms obtained at ages 8-16 years (n = 431) were assessed for good visibility of cephalometric structures, including the sella turcica, and the absence of craniofacial congenital deformities; finally, 322 cephalograms were included and analysed. Subsequently, anomalies of sella turcica have been identified. Hypertrophic posterior clinoid process, hypotrophic posterior clinoid process and oblique contour of the floor were the abnormalities found that could not be classified based on literature. The study group consisted of 151 cephalograms with abnormal sella turcica, while the control group consisted of 171 cephalograms without any sellar pathology. Data normality has been tested using Shapiro-Wilk test. Correlations with age were made using Spearman correlation coefficient and those with sex were made using independence test with Yate's correction for continuity. Mann-Whitney test was used to compare between groups and subgroups. The level of significance has been established as p < 0.05.
Sellar anomalies were found in 151 individuals (46.9%). Statistically significant differences between patients with normal and abnormal sellar morphology were found concerning: Pg:NB (p = 0.0009), 1+:NA (p = 0.0004) and 1-:NB (p = 0.012), indicating a more distal position of jaw structures in subjects with abnormal sella.
The finding that almost 50% of children with malocclusion have sellar abnormalities confirms a general aetiology of malocclusion. Sella turcica assessment should be carried out during cephalometric analysis.
The aim of this study was to examine the association of single-nucleotide polymorphisms (SNPs) in the gene encoding ficolin-2 protein (FCN2 gene) at positions -986 (rs17514136), -602 (rs3124953), and ...-4 (rs3124952) with dental caries in Polish children. Two hundred and sixty Polish Caucasian children aged 15 years were enrolled in this study: 82 with "higher" caries experience (DMFT >5) and 178 with "lower" caries experience (DMFT ≤5). In addition, subjects with caries experience (DMFT ≥1) and caries-free subjects (DMFT = 0) were compared. FCN2 SNPs were genotyped with PCR-RFLP methods. There were no significant differences in the genotype, allele, or haplotype distributions in 3 analyzed SNPs of the FCN2 gene between children with "higher" and those with "lower" caries experience as well as between children with caries experience and caries-free children. In conclusion, we did not find any association of FCN2 promoter polymorphisms at positions -986, -602, and -4 with dental caries in Polish children.
The ATLAS Forward Proton (AFP) detector consists of two forward detectors located at 205 m and 217 m on either side of the ATLAS experiment. The aim is to measure the momenta and angles of ...diffractively scattered protons. In 2016, two detector stations on one side of the ATLAS interaction point were installed and commissioned. The detector infrastructure and necessary services were installed and are supervised by the Detector Control System (DCS), which is responsible for the coherent and safe operation of the detector. A large variety of used equipment represents a considerable challenge for the AFP DCS design. Industrial Supervisory Control and Data Acquisition (SCADA) product Siemens WinCCOA, together with the CERN Joint Control Project (JCOP) framework and standard industrial and custom developed server applications and protocols are used for reading, processing, monitoring and archiving of the detector parameters. Graphical user interfaces allow for overall detector operation and visualization of the detector status. Parameters, important for the detector safety, are used for alert generation and interlock mechanisms.
Abstract Oblique facial clefts are extremely rare congenital deformities with a reported incidence of 0.24% of all facial clefts. This report presents a patient with a right-sided oblique cleft ...extending through the upper lip, the alar groove and the lower palpebra accompanied by a left-sided complete cleft lip and palate. Hypertylorism and bilateral microphthalmia as well as flexion wrist contractures were also present. Primary straight-line closure of the oblique cleft was undertaken followed by primary closure of the contralateral cleft lip. The treatment modality and 2 year follow-up results are presented.
To cite this article:
Fudalej P, Janiszewska‐Olszowska J, Wedrychowska‐Szulc B, Katsaros C: Early alveolar bone grafting has a negative effect on maxillary dental arch dimensions of pre‐school ...children with complete unilateral cleft lip and palate Orthod Craniofac Res 2011;14:51–57
Structured
Authors – Fudalej P, Janiszewska‐Olszowska J, Wedrychowska‐Szulc B, Katsaros C.
Objective – To evaluate maxillary dental arch dimensions in pre‐school children with a complete unilateral cleft lip and palate (CUCLP) after early alveolar bone grafting.
Material and Methods – Intercanine and intermolar widths, length of dental arch and mesiopalatal inclination of both maxillary segments were measured directly on the dental casts of 42 children (27 boys and 15 girls; mean age = 5.2 years, SD 0.5; Early‐grafted group), 30 children (18 boys and 12 girls; mean age = 5.8 years, SD 0.8; Non‐grafted group), and 40 children (25 boys and 15 girls, mean age = 5.8, SD 0.4; non‐cleft Control group). Children from Early‐grafted and Non‐grafted groups had a CUCLP repaired with a one‐stage closure of the entire cleft. An alveolar bone grafting was performed in the Early‐grafted group between 2 and 4 years (mean = 2.4, SD 0.6). A one‐way anova model with post hoc Tukey’s multiple comparison procedures were used to identify intergroup differences.
Results – The mesiopalatal inclination of the lesser segment in the Early‐grafted group was decreased in comparison with the Non‐grafted and Control groups. The intercanine width had a tendency to be reduced in the Early‐grafted group relative to Non‐grafted group.
Conclusions – Early bone grafting results in a larger collapse of the lesser segment than bone grafting carried out between 9 and 12 years of age.
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