In this work a new nonoverconstrained redundant decoupled robot, free of compound joints, formed from three parallel manipulators, with two moving platforms and provided with six active limbs ...connected to the fixed platform, called LinceJJP, is presented. Interesting applications such as multi-axis machine tools with parallel kinematic architectures, solar panels, radar antennas, and telescopes are available for this novel spatial mechanism.
The geometry of zwitterionic liquids (ZL) into the simulation cell, these are constituted by polyglycols derived from ethylene oxide and propylene oxide, in conjunction with two hydroxyl groups, ...alkyl amines, acrylic acid. The interaction between these structures and both calcite surface and asphaltene structure indicates changes in wettability of oil–rock–ZL system.
•We model two zwitterionic structures, ZL10 and ZL13, for enhanced oil recovery.•Geometry, stability, global reactivity indexes, and frontier orbital were calculated.•We determine the nature of the possible supramolecular interactions.•The structures studied are more stable than the cocamidopropyl betaine.•The structures studied are less reactive than the cocamidopropyl betaine.
In this work, we present a quantum chemical study pertaining to some supramolecular complexes acting as wettability modifiers of oil–water–limestone system. The complexes studied are derived from zwitterionic liquids of the types N′-alkyl-bis, N-alquenil, N-cycloalkyl, N-amyl-bis-beta amino acid or salts acting as sparkling agents. We studied two molecules of zwitterionic liquids (ZL10 and ZL13), HOMO and LUMO levels, and the energy gap between them, were calculated, as well as the electron affinity (EA) and ionization potential (IP), chemical potential, chemical hardness, chemical electrophilicity index and selectivity descriptors such Fukui indices. In this work, electrochemical comparison was realized with cocamidopropyl betaine (CPB), which is a structure zwitterionic liquid type, nowadays widely applied in enhanced recovery processes.
Acute cholangitis: a literature review Orozco, Cesár A. O.; Fuentes, Alberto B.; Gutiérrez, Félix O. ...
International Surgery Journal,
11/2022, Letnik:
9, Številka:
12
Journal Article
Odprti dostop
Acute cholangitis is a disease that occurs when a stricture or obstruction of the bile duct causes cholestasis and/or infection. Biliary stricture or obstruction elevates the pressure in the biliary ...system and causes reflux of microorganisms or endotoxins from the infected bile into the systemic circulation, which induces a systemic inflammatory response. The Charcot triad provides high specificity, however, due to its low sensitivity (50-70%), it is very limited to make a diagnosis of cholangitis alone. Therefore, the most current guidelines suggest specific criteria for diagnosis. Antibiotic treatment is a fundamental pillar in the management of patients with cholangitis. The treatment must be carried out depending on the severity (grade I-III).
A new spatial hyper-redundant manipulator Gallardo, Jaime; Orozco, Horacio; Rico, José M. ...
Robotics and computer-integrated manufacturing,
08/2009, Letnik:
25, Številka:
4
Journal Article
Recenzirano
This work presents a novel hyper-redundant manipulator. Such a manipulator is built with a variable number of tandem-assembled modules. Each module consists of a 3-dof parallel manipulator with ...asymmetric extremities in which moving platform possesses mixed motions with respect to the base platform. The manipulator's architecture is so simple that the forward position analysis is presented in closed-form solution, more specifically, in echelon-form solution. On the other hand, the velocity and acceleration analyses are carried out using the theory of screws. Finally, a case study consisting of solving the kinematic analysis of a 30-dof hyper-redundant manipulator is presented.
In this work the forward position analysis of parallel manipulators with identical limbs, type revolute-prismatic-spherical (RPS), is carried out applying recursively the Sylvester dialytic ...elimination method. Afterwards, the velocity and acceleration analyses of the mechanisms at hand are addressed using the theory of screws. A numerical example is provided to prove the efficacy of the chosen methodology for the kinematic analyses of the mechanisms under study.
Methadone and buprenorphine are the most prevalent types of opioid maintenance programs in Andalusia. The main objective is comparing the functional status of patients with pharmacological opioid ...maintenance treatments according to different socio-demographic characteristic, health and disabilities domains and sexual difficulties.
A total of 593 patients from the Andalusia community, 329 were undergoing methadone treatment and 264 were undergoing buprenorphine treatment. The patients were interviewed by socio-demographic and opioid-related variables, assessed by functioning, disability and health domains (WHODAS 2.0.) and for sexual problems (PRSexDQ-SALSEX).
We found significant differences in the socio-demographic and the opioid-related variables as the onset of opioid use, being on previous maintenance programs, opioid intravenous use, the length of previous maintenance programs, polydrug use and elevated seroprevalence rates (HCV and HIV) between the methadone group and the buprenorphine group. Regarding health and disability domains there were differences in the Understanding and communication domain, Getting around domain, Participation in society domain and in the WHODAS 2.0. simple and complex score, favoring buprenorphine-treated patients. The methadone group referred elevated sexual impairments compared with the buprenorphine group. Opioid-related variables as seroprevalence rates, other previous lifetime maintenance program, the daily opioid dosage and the daily alcohol use are the most discriminative variables between both groups. Participation in society variables and sexual problems were the most important clinical variables in distinguishing the methadone group from the buprenorphine group regarding their functional status.
The methadone group showed higher prevalence in opioid dependence-related variables, elevated disabilities in participation in society activities and sexual problems compared with the buprenorphine group. This study shows the importance of carry out a functional evaluation in the healthcare follow-up, especially in those areas related with social activity and with sexual problems.
The Caenorhabditis elegans spermatheca is a myoepithelial tube that stores sperm and undergoes cycles of stretching and constriction as oocytes enter, are fertilized, and exit into the uterus. ...FLN-1/filamin, a stretch-sensitive structural and signaling scaffold, and PLC-1/phospholipase C-epsilon, an enzyme that generates the second messenger IP.sub.3, are required for embryos to exit normally after fertilization. Using GCaMP, a genetically encoded calcium indicator, we show that entry of an oocyte into the spermatheca initiates a distinctive series of IP.sub.3-dependent calcium oscillations that propagate across the tissue via gap junctions and lead to constriction of the spermatheca. PLC-1 is required for the calcium release mechanism triggered by oocyte entry, and FLN-1 is required for timely initiation of the calcium oscillations. INX-12, a gap junction subunit, coordinates propagation of the calcium transients across the spermatheca. Gain-of-function mutations in ITR-1/ IP.sub.3R, an IP.sub.3-dependent calcium channel, and loss-of-function mutations in LFE-2, a negative regulator of IP.sub.3 signaling, increase calcium release and suppress the exit defect in filamin-deficient animals. We further demonstrate that a regulatory cassette consisting of MEL-11/myosin phosphatase and NMY-1/non-muscle myosin is required for coordinated contraction of the spermatheca. In summary, this study answers long-standing questions concerning calcium signaling dynamics in the C. elegans spermatheca and suggests FLN-1 is needed in response to oocyte entry to trigger calcium release and coordinated contraction of the spermathecal tissue.
This work analyzes a prototype of a quasi-switched boost inverter (qSBI) feeding an isolated resistive load from a DC source. The use of spatial vector pulse width modulation (SPWM) with triangular ...comparison is proposed to increase the qSBI gain factor, and its performance is contrasted with other types of spatial vector modulations, such as discontinuous modulations. To verify the validity of the method for voltage range extension in the qSBI converter, a semi-customized test platform was developed. This platform uses a DSP floating point card (Analog Devices ADSP-21369) for processing and control strategies and an interface card that includes a programmable logic array (FPGA) from Xilinx (Spartan-3), which allows to develop the synchronized modulation qSBI needs. The experimental results show improvements in the performance of the qSBI converter in terms of gain factor, voltage reduction in the capacitor, and input current profiles. Discontinuous space vector modulation strategies do not perform well when compared to continuous SVPWM or SPWM modulations, because the ripple levels in the currents taken from the PV module are approximately twice as great as in continuous modulation techniques. Finally, the usefulness of a qSBI as PV microinverter is confirmed by two practical experimental cases of a PV photovoltaic system with a maximum power point adjustment algorithm (MPPT).
The Caenorhabditis elegans spermatheca is a myoepithelial tube that stores sperm and undergoes cycles of stretching and constriction as oocytes enter, are fertilized, and exit into the uterus. ...FLN-1/filamin, a stretch-sensitive structural and signaling scaffold, and PLC-1/phospholipase C-ζ, an enzyme that generates the second messenger IP.sub.3, are required for embryos to exit normally after fertilization. Using GCaMP, a genetically encoded calcium indicator, we show that entry of an oocyte into the spermatheca initiates a distinctive series of IP.sub.3-dependent calcium oscillations that propagate across the tissue via gap junctions and lead to constriction of the spermatheca. PLC-1 is required for the calcium release mechanism triggered by oocyte entry, and FLN-1 is required for timely initiation of the calcium oscillations. INX-12, a gap junction subunit, coordinates propagation of the calcium transients across the spermatheca. Gain-of-function mutations in ITR-1/ IP.sub.3R, an IP.sub.3-dependent calcium channel, and loss-of-function mutations in LFE-2, a negative regulator of IP.sub.3 signaling, increase calcium release and suppress the exit defect in filamin-deficient animals. We further demonstrate that a regulatory cassette consisting of MEL-11/myosin phosphatase and NMY-1/non-muscle myosin is required for coordinated contraction of the spermatheca. In summary, this study answers long-standing questions concerning calcium signaling dynamics in the C. elegans spermatheca and suggests FLN-1 is needed in response to oocyte entry to trigger calcium release and coordinated contraction of the spermathecal tissue.
The Caenorhabditis elegans spermatheca is a myoepithelial tube that stores sperm and undergoes cycles of stretching and constriction as oocytes enter, are fertilized, and exit into the uterus. ...FLN-1/filamin, a stretch-sensitive structural and signaling scaffold, and PLC-1/phospholipase C-straight epsilon, an enzyme that generates the second messenger IP3, are required for embryos to exit normally after fertilization. Using GCaMP, a genetically encoded calcium indicator, we show that entry of an oocyte into the spermatheca initiates a distinctive series of IP3-dependent calcium oscillations that propagate across the tissue via gap junctions and lead to constriction of the spermatheca. PLC-1 is required for the calcium release mechanism triggered by oocyte entry, and FLN-1 is required for timely initiation of the calcium oscillations. INX-12, a gap junction subunit, coordinates propagation of the calcium transients across the spermatheca. Gain-of-function mutations in ITR-1/IP3R, an IP3-dependent calcium channel, and loss-of-function mutations in LFE-2, a negative regulator of IP3 signaling, increase calcium release and suppress the exit defect in filamin-deficient animals. We further demonstrate that a regulatory cassette consisting of MEL-11/myosin phosphatase and NMY-1/non-muscle myosin is required for coordinated contraction of the spermatheca. In summary, this study answers long-standing questions concerning calcium signaling dynamics in the C. elegans spermatheca and suggests FLN-1 is needed in response to oocyte entry to trigger calcium release and coordinated contraction of the spermathecal tissue.
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