Corporate Social Responsibility (CSR) becomes popular as big international firms gain more power than states and global issues engender concerns to people from all over the world. The pandemic of ...novel coronavirus is a current issue of global concern that threats humanity and global economy since the end of 2019. A lot of firms have announced urgent actions to support their employees and the local communities. The present study aims to examine whether the CSR activities of firms due to the pandemic could be categorized either as strategical or tactical CSR. The researcher recognizes the formation of a new kind of CSR called critical CSR as a hybrid between tactical and strategical CSR sharing characteristics from both. The examination of the case of Greece during the pandemic has provided a variety of examples of CSR activities from big Greek international firms that have been processed to support the validity of the reasoning. Finally, the paper delineates this new universal form of CSR born under the critical circumstances of the pandemic and the ensuing economic recession. That fact proves that this crisis could be transformed into a chance for corporations to realize their social role and improve their CSR footprint with the learnings of this pandemic by underlining possible advantages of these urgent CSR actions that could be incorporated into the usual CSR policy of the firms.
We explored whether radiomic features from T1 maps by cardiac magnetic resonance (CMR) could enhance the diagnostic value of T1 mapping in distinguishing health from disease and classifying cardiac ...disease phenotypes. A total of 149 patients (n = 30 with no heart disease, n = 30 with LVH, n = 61 with hypertrophic cardiomyopathy (HCM) and n = 28 with cardiac amyloidosis) undergoing a CMR scan were included in this study. We extracted a total of 850 radiomic features and explored their value in disease classification. We applied principal component analysis and unsupervised clustering in exploratory analysis, and then machine learning for feature selection of the best radiomic features that maximized the diagnostic value for cardiac disease classification. The first three principal components of the T1 radiomics were distinctively correlated with cardiac disease type. Unsupervised hierarchical clustering of the population by myocardial T1 radiomics was significantly associated with myocardial disease type (chi
= 55.98, p < 0.0001). After feature selection, internal validation and external testing, a model of T1 radiomics had good diagnostic performance (AUC 0.753) for multinomial classification of disease phenotype (normal vs. LVH vs. HCM vs. cardiac amyloid). A subset of six radiomic features outperformed mean native T1 values for classification between myocardial health vs. disease and HCM phenocopies (AUC of T1 vs. radiomics model, for normal: 0.549 vs. 0.888; for LVH: 0.645 vs. 0.790; for HCM 0.541 vs. 0.638; and for cardiac amyloid 0.769 vs. 0.840). We show that myocardial texture assessed by native T1 maps is linked to features of cardiac disease. Myocardial radiomic phenotyping could enhance the diagnostic yield of T1 mapping for myocardial disease detection and classification.
The proposed novel “BathySent” approach for coastal bathymetric mapping, using the Copernicus Sentinel-2 mission, as well as the assessment and specification of the uncertainties of the derived depth ...results, are the objectives of this research effort. For this reason, Sentinel-2 bathymetry retrieval results for three different pilot sites in Greece (islands of Kos, Kasos, and Crete) were compared with ground-truth data. These data comprised high-resolution swath bathymetry measurements, single-beam echosounder measurements at very shallow waters (1–10 m), and the EMODnet DTM 2018 release. The synthetic tests showed that the “BathySent” approach could restitute bathymetry in the range of 5–14 m depth, showing a standard deviation of 2 m with respect to the sonar-based bathymetry. In addition, a comparison with the “ratio model” multispectral technique was performed. The absolute differences between conventional Earth Observation-based bathymetry retrieval approaches (i.e., linear ratio model) and the suggested innovative solution, using the Sentinel-2 data, were mainly lower than 2 m. According to the outcome evaluation, both models were considered to provide results that are more reliable within the depth zone of 5–25 m. The “ratio model” technique exhibits a saturation at ~25 m depth and demands ground calibration. Though, the “BathySent” method provides bathymetric data at a lower spatial resolution compared to the “ratio model” technique; however, it does not require in situ calibration and can also perform reliably deeper than 25 m.
Increasing morbidity of cardiovascular diseases in modern society has made it crucial to develop artificial small-caliber cardiovascular grafts for surgical intervention of diseased natural arteries, ...as alternatives to the gold standard autologous implants. Synthetic small-caliber grafts are still not in use due to increased risk of restenosis, lack of lumen re-endothelialization and mechanical mismatch, leading sometimes either to graft failure or to unsuccessful remodeling and pathology of the distal parts of the anastomosed healthy vascular tissues. In this work, we aimed to synthesize small-caliber polymeric (polycaprolactone) tissue-engineered vascular scaffolds that mimic the structure and biomechanics of natural vessels. Electrospinning was implemented to prepare microstructured polymeric membranes with controlled axis-parallel fiber alignment. Consequently, we designed small-caliber multilayer anisotropic biodegradable nanofibrous tubular scaffolds, giving attention to their radial compliance. Polycaprolactone scaffold morphology and mechanical properties were assessed, quantified, and compared with those of native vessels and commercial synthetic grafts. Results showed a highly hydrophobic scaffold material with a three-layered tubular morphology, 4-mm internal diameter/0.25 ± 0.09-mm thickness, consisting of predominantly axially aligned thin (1.156 ± 0.447 μm), homogeneous and continuous microfibers, with adequate (17.702 ± 5.369 μm) pore size, potentially able to promote cell infiltration in vivo. In vitro accelerated degradation showed a 5% mass loss within 17–25 weeks. Mechanical anisotropy was attained as a result, almost one order of magnitude difference of the elastic modulus (18 ± 3 MPa axially/1 ± 0.3 MPa circumferentially), like that of natural arterial walls. Furthermore, a desirable radial compliance (5.04 ± 0.82%, within the physiological pressure range) as well as cyclic stability of the tubular scaffold was achieved. Finally, cytotoxicity evaluation of the polymeric scaffolds revealed that the materials were nontoxic and did not release substances harmful to living cells (over 80% cell viability achieved).
Trends in the vertical displacement (i.e. uplift or subsidence) of the Aegean Sea coastal zone have been assessed by comparing observational data with those derived from the predictive ...glacio-hydro-isostatic model of Lambeck and Purcell (2005) for a period spanning from the Mesolithic to the late Roman times. The data base comprises published studies that use both geomorphological (with associated biological material) and archaeological sea level indicators/markers. Localities demonstrating uplift of high amplitude were detected in front of the Hellenic Arc (Antikythira, Crete, Rhodes, Nisyros) and in the northeast Aegean region (Thrace), whilst areas experiencing tectonic subsidence were mainly observed in the central Aegean region which is characterized by an extensional tectonic domain. However, regional-scale tectonic particularities have caused uplift in parts of the west and east coast of central Aegean. Tectonically ‘stable’ sites can be found in the Cyclades Plateau, however, this is due to a balance between uplifting and subsiding movements. Sediment compaction and sediment loading may have affected districts with high sedimentation rates such as the Thessaloniki Plain-Thermaikos Gulf (NW Aegean). Finally, tectonic fragmentation of the coastal area in Minor Asia is responsible for localised uplifting and subsiding events.
Colon cancer is a major public health issue, affecting a growing number of individuals worldwide. Proper and early diagnosis of colon cancer is the necessary first step toward effective treatment ...and/or prevention of future disease relapse. Artificial intelligence and its subtypes, deep learning in particular, tend nowadays to have an expanding role in all fields of medicine, and diagnosing colon cancer is no exception. This report aims to summarize the entire application spectrum of deep learning in all diagnostic tests regarding colon cancer, from endoscopy and histologic examination to medical imaging and screening serologic tests.
Sediment transport processes from the slopes to the deep basins were studied in the southern Cretan margin (Eastern Mediterranean) by means of swath bathymetry, seismic reflection (airgun) profiling, ...and gravity coring. Mud/silt turbidites, developed in structureless or laminated patterns, appear to dominate the continental slope and the 2700–3600-m deep depressions of Samaria, Messara, and Gortys. These deposits are the result of successive mass transport events and turbidity currents. Over-steepening caused by strike–slip shearing associated with extensional tectonic activity in the shallow crustal levels, shaking due to significant seismic activity, and the presence of weak sediment layers are responsible for frequent triggering of slope failures and the subsequent formation of turbidity currents on the Gavdos slope. On the Cretan slope, sediments channeled as turbidity currents through canyons proved to be the major delivery mechanism, together with debris flows. Subordinate contributions of hemipelagic sediments occur only in the Messara basin. Moreover, steep non-incised slope areas and slope-confined canyons of the Gavdos slope were found to provide comparable sediment contribution with the fluvially connected canyons of the Cretan slope.
The foreseeable acceleration of global sea level rise could potentially pose a major threat to the natural charm and functional integrity of the world-renowned tourist coastal attractions of Rhodes ...Island, as a result of the anticipated increasing frequency of flooding and erosion events. Hence, this study aims to determine the most vulnerable segments (in terms of physical impact) of the Rhodes coastline through the widely accepted coastal vulnerability index (CVI), applying a combination of well-known, broadly used approaches and methods. The frequency distribution of the current CVI along the island’s coastline suggests a rather worrying high to very high vulnerability of 40%. In addition, a CVI projection to the end of the 21st century (based on the Intergovernmental Panel on Climate Change predictive scenarios) indicates an enhancement of the total vulnerability by 48%, mainly focused on the majority of the western coastline. Hence, a considerable number of popular coastal destinations in the island shall remain under unignorable threat and, therefore, coastal managers and decision-makers need to hatch an integrated plan to minimize economic and natural losses, private property damage and tourism infrastructure deterioration from flooding and erosion episodes, which will most likely be intensified in the future.
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