Resumo A membrana espermática é rica em ácidos graxos poliinsaturados, o que a torna sensível à ação de espécies reativas de oxigênio, que podem prejudicar a qualidade seminal dos cachaços. O ...objetivo do presente estudo foi avaliar o efeito da suplementação de duas fontes de selênio em diferentes doses. Trinta e cinco cachaços foram distribuídos em quatro grupos: (INOR30) 0,30 ppm de selenito de sódio; (COMP30) 0,30 ppm de metal-aminoácido de selênio; (MISTO15+15) 0,15 ppm de selenito de sódio + 0,15 ppm de metal-aminoácido de selênio e (COMP15) 0,15 ppm de metal-aminoácido de selênio. Os ejaculados dos cachaços foram avaliados durante 22 semanas, resultando em 210 amostras avaliadas para volume, motilidade, pH, presença de aglutinação e alterações morfológicas, e 140 amostras para concentração espermática. Os dados foram analisados com medidas repetidas no tempo em modelo misto, em que o tipo de suplementação de selênio, os períodos de avaliação (um período de duas semanas + cinco períodos de quatro semanas) e suas interações foram os efeitos fixos, e o animal e o funcionário que coletou os ejaculados foram os efeitos aleatórios. Os resultados obtidos demonstraram não haver diferença na suplementação de selênio com as fontes e doses utilizadas. Com isso, foi possível verificar que o metal-aminoácido de selênio na dose de 0,15 ppm promove o mesmo efeito das dietas formuladas com 0,30 ppm de selenito de sódio.
Abstract The spermatic membrane is rich in polyunsaturated fatty acids, which makes it sensitive to the action of reative species of oxygen, which can damage the seminal quality of the scraps. The purpose of this study was to evaluate the effect of the supplementation of two selenium sources at different doses. Third five scraps were allocated in four groups: (INOR30) 0.30 ppm sodium selenite; (COMP30) 0.30 ppm selenium metal-amino acid; (MIXED15+15) 0.15 ppm sodium selenite + 0.15 ppm selenium metal-amino acid and (COMP15) 0.15 ppm selenium metal-amino acid. The ejaculates of the scraps were evaluated over 22 weeks, resulting in 210 samples evaluated for volume, motility, pH, presence of agglutination and morphological changes, and 140 samples for spermatic concentration. The data was analyzed with repeated measures in time in a mixed model with type of selenium supplementation, periods of evaluation (one period of two weeks + five periods of four weeks) and their interactions as fixed effects, and animal and the worker that collected the ejaculates as random effects. Results showed no difference in selenium supplementation with the sources and doses used. In this way, it was possible to verify that the metal amino acid of selenium at the dose of 0.15 ppm promotes the same effect as the diets formulated with 0.30 ppm of sodium selenite.
Elastomer thermoplastics are a class of polymeric materials that received industry attention due to the possibility of joining the elastic of elastomers with the thermoplastics processability. The ...synergistic properties are linked to the appropriate processing. This study evaluated the effect of rotor speed during polymer mixing and the dynamic vulcanization process of polypropylene and nitrile rubber blends. Bismaleimide was employed as multipurpose agent (crosslinking coagent for peroxide and compatibilizer). Morphology, mechanical properties, compression set and oil resistance tests were evaluated for compositions containing 50 and 70 PHR of elastomer. The compatibilization of TPV was realized by infrared spectroscopy. It was shown a compatibilizer effect and better dispersion, achieving the inversion phase, only studying the effect of processing conditions (rotor speed, addition sequence, additives), without any extra interfacial agent. There is a tendency to obtain better performance with decrease speed at dynamic vulcanization or/and at torque stabilization, mainly for blends with 50 PHR of rubber.
An infectious disease caused by SARS-CoV-2, COVID-19 greatly affects the pediatric population and is 3 times more prevalent in newborns than in the general population. In newborns, the overexpression ...of immunological molecules may also induce a so-called cytokine storm. In our study, we evaluated the expression of cytokines in newborns admitted to a neonatal ICU whose mothers had SARS-CoV-2 and symptoms of SARS. The blood of newborns of infected and healthy mothers was collected to identify their Th1 and Th2 cytokine profiles, and via flow cytometry, the cytokines TNF-α, IFN-γ, IL-2, IL-6, and IL-10 were identified. Overexpression was observed in the Th1 and Th2 cytokine profiles of newborns from infected mothers compared with the control group. Statistical analysis also revealed significant differences between the cellular and humoral responses of the infected group versus the control group. The cellular versus humoral responses of the newborns of infected mothers were also compared, which revealed the prevalence of the cellular immune response. These data demonstrate that some cytokines identified relate to more severe symptoms and even some comorbidities. IL-6, TNF-α, and IL-10 may especially be related to cytokine storms in neonates of mothers with COVID-19.
The use of coconut fiber as a copper adsorbent in cachaça was optimised, and changes in the chemical quality of the beverage were observed by analytical techniques. The influence of the adsorbent ...mass and copper concentration parameters was investigated using the Central Composite Design, and the optimum condition was obtained through the use of Response Surface Methodology. The equilibrium of the adsorption reaction was obtained within 120 min. The kinetic data were better adjusted for the Elovich model (Elovich and Zhabrova
1939
) and the isotherm data for the Sips model (Sips
1948
). The maximum adsorption capacity was 1.38 mg g
−1
. Slight changes in the physicochemical quality of the beverage were observed, including a decrease in volatile acidity and alcohol content. Copper levels in cachaça decreased from 8.57 mg L
−1
to 4.97 mg L
−1
after adsorption. Therefore, the use of biomass as a metal ion adsorbent in beverages can be successfully employed.
Background
Recurrent Pregnancy Loss (RPL) and Recurrent Implantation Failure (RIF) are highly heterogeneous condition and many of the mechanisms involved still require elucidation. The aim was to ...analyze the lipidomic profile in plasma of women with RPL and RIF before and after receiving the Lipid Emulsion Therapy (LET) containing 10% fish oil (SMOFlipid® 20%).
Methods
This study included twenty‐six women with RPL or RIF from immunological or inflammatory causes, with elevated natural killer cell levels and divided into a Pregnancy Loss or a Live Birth group according to the outcome. The women received intravenous LET and sample collecting was done before the first, third and fifth dose of LET in the pregnant women. Ultra‐performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC‐QTOF MS) and multivariate statistical methods were performed to evaluate the profile of phospholipids present in the women's plasma.
Results
An increase of phosphatidylcholines (PC) 40:8 and 36:5 levels with predominance of n6 polyunsaturated fatty acids (PUFA) was observed in plasma lipids of the Pregnancy Loss Group compared to Live Birth Group. We also observed an increase in the relative abundance of n3 PUFA‐PC species (42:10 and 36:6) and LysoPC 15:0 with the long term use of LET.
Conclusion
The greater availability of n3 PUFA in plasma of the pregnant women stemming from LET use can be considered advantageous regarding the alteration of the phospholipid profile and its postulated anti‐inflammatory and immunomodulatory role.
de Paula, T, Neves, MF, da Silva Itaborahy, A, Monteiro, W, Farinatti, P, and Cunha, FA. Recovery pattern of cardiac autonomic control after aerobic and strength exercises in overweight ...prehypertensive men. J Strength Cond Res 33(10): 2743-2752, 2019-The extent to which postexercise cardiac autonomic control depends on exercise modality remains unclear, particularly among individuals with autonomic dysfunction (cardiac autonomic dysfunction CADysf). This study compared heart rate variability (HRV) and baroreflex sensitivity (BRS) responses to acute aerobic exercise (AE) and strength exercise (SE) in men with CADysf. Twenty men were assigned into control (n = 10: 33.8 ± 3.0 years; 23.7 ± 1.5 kg·m) and CADysf (n = 10: 36.2 ± 9.8 years; 28.4 ± 2.6 kg·m) groups. Cardiac autonomic dysfunction underwent AE, SE, and a nonexercise control day (control session CTL) in a randomized, counter-balanced order. Heart rate variability and BRS were assessed in a supine position during 25 minutes of recovery after AE, SE, and CTL. Both HRV indices (p ≤ 0.05; effect size Cohen's d: >1.4) and BRS at rest were significantly lower in CADysf than those in controls (p < 0.01; effect size Cohen's d: ≥1.36). In CADysf, postexercise increases in heart rate, sympathetic activity (low-frequency LF band), and sympathovagal balance (LF:high-frequency HF ratio), as well as decreases in R-R interval, parasympathetic activity (HF band), and BRS were observed in AE (p ≤ 0.05; effect size Cohen's d: ≥1.31) and SE (p ≤ 0.05; effect size Cohen's d: ≥0.79) vs. CTL, but changes were larger after AE than SE (p ≤ 0.05; effect size Cohen's d: ≥0.73). In conclusion, both AE and SE elicited postexercise changes in HRV and BRS among CADysf men, primarily reflected by lowered vagal modulation, increased sympathovagal balance, and a delayed BRS recovery pattern. However, those changes seem to be more likely to occur after AE than SE.
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•Novel yttrium metallosilicate was synthesized by sol-gel chemistry.•XRD, FT-IR, 29Si MAS-NMR, 89Y MAS-NMR data indicated a mixed framework structure.•High adsorption for Pb2+ (94 %) ...and Cd2+(74 %) from aqueous medium was observed.•Pseudo-First Order (PFO) and Pseudo-Second Order (PSO) fitted the kinetic curves.•Kinect data indicate chemisorption of lead onto the yttrium metallosilicate.
A new metallosilicate based on yttrium was synthesized and characterized by XRD, FT-IR, 29Si MAS-NMR, and 89Y MAS-NMR. The mixed framework of the material was confirmed by the detection of distinct chemical shift groups using 29Si MAS-NMR (at -82 to -87 ppm, -91 to -94 ppm, -96 to -102 ppm, and -105 to -108 ppm), as well as four distinct chemical shifts in the 89Y MAS-NMR spectrum (at -89, -142, -160, and -220 ppm). Adsorption and kinetic analyses indicated the potential of the new material for the removal of lead and cadmium from aqueous media. The adsorption results for lead indicated that dynamic equilibrium was reached after five hours, with total lead removal of around 94 %, while for cadmium it was reached in the first hour, with total cadmium removal of around 74 %. The adsorptions of lead and cadmium were modeled using pseudo-first order (PFO) and pseudo-second order (PSO) kinetic models. Although both models provided high R2 values (0.9903 and 0.9980, respectively), the PSO model presented a much lower χ2red value (4.41 × 10−4), compared to the PFO model (2.12 × 10−3), which indicated that the rate-limiting step was probably due to the chemisorption of lead from the solution onto the yttrium-based metallosilicate.
Abstract The goal of this study was to assess the effects of uniformization management, birth order (BO), birth weight (BiW) and their interactions on the performance of piglets in the maternity ...phase. Sows (n = 25) and their litters (n = 388 piglets) were distributed into two treatments, namely: UNIF - uniformization of piglets between different litters right after birth; and BIOM - piglets kept up to 12 hours after birth with their biological mothers. In both treatments, the effect of BO was assessed in three groups characterised by BO of 1-6, 7-12, and ≥13. The effect of BiW was assessed in four groups defined as ‘very light’, ‘light’, ‘medium’, and ‘heavy’. The design was completely randomised in a 2×3×4 factorial scheme, totalling 24 treatments with 16 piglets/treatment, on average. Weight gain from birth to 72 hours after birth (WG72h) was greater in the BIOM treatment. The colostrum intake (CI) was lower in piglets with BO ≥13. In general, piglet performance increased in response to the increase in BiW. There was interaction between uniformization management and BiW with respect to CI related to body weight (CIBW), which was greater in very light piglets in the UNIF treatment (27.48% BW), and lower in heavy piglets in the BIOM treatment (16.82% BW). It was possible to obtain satisfactory piglet performance by keeping the litters with their biological mothers until 12 hours after birth. The CI expressed on an absolute basis (g) was greater; however, CI expressed on relative basis with respect to body weight (% BW) was lower in heavy piglets.
Resumo O objetivo deste trabalho foi avaliar os efeitos de manejo de uniformização, ordem de nascimento (ON), peso ao nascimento (PN) e suas interações no desempenho de leitões na fase de maternidade. Porcas (n = 25) e suas leitegadas (n = 388 leitões) foram distribuídas em dois tratamentos: UNIF - uniformização de leitões entre leitegadas distintas logo após o nascimento; MBIO - leitões mantidos até 12 horas pós-parto com a mãe biológica. Nos dois tratamentos o efeito da ON foi avaliado em três grupos caracterizados pela ON de 1-6, 7-12 e ≥ 13; o efeito de PN foi avaliado em quatro grupos definidos como Muito leve, Leve, Médio e Pesado. O delineamento foi inteiramente casualizado em esquema fatorial 2 × 3 × 4, totalizando 24 tratamentos com 16 leitões/tratamento, em média. O ganho de peso do nascimento até 72 horas de vida (GP72h) foi maior em MBIO. A quantidade de colostro ingerida (QCI) foi menor em leitões de ON ≥ 13. Em geral, o desempenho dos leitões aumentou em resposta ao aumento do PN. Houve interação entre manejo de uniformização e PN para QCI em relação ao peso corporal (QCIPC), que foi maior em leitões Muito leves em UNIF (27,48% PC) e menor em leitões Pesados em MBIO (16,82% PC). É possível obter bom desempenho de leitões mantendo a leitegada com a mãe biológica até 12 horas pós-parto. A quantidade de colostro ingerida em base absoluta (g) é maior, mas relativa ao peso corporal (% PC) é menor em leitões pesados.
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•Stannosilicate was synthesized and characterized by XRD,SEM and solid-state MAS NMR.•XRD and solid-state MAS NMR revealed a structure of OPT metallosilicate.•The material was applied ...as heterogeneous catalyst for biodiesel production.•FAMEs or FAEEs yields higher than 90.0% using refined edible and non-edible oils.•FAEEs yield of 96.6% was obtained by the conversion of refined microalgae oil.
This study reports the synthesis, physicochemical characterization by X-ray powder diffraction (XRD), scanning electron microscopy (SEM) and solid-state MAS NMR (1H, 23Na, 29Si and 119Sn MAS NMR) of a metallo-stannosilicate and its application as a heterogeneous catalyst for biodiesel production via ethanolysis and methanolysis routes using edible, non-edible an waste oils as feedstocks. XRD characterization of the metallo-stannosilicate has revealed a typical structure of mixed octahedral-pentahedral-tetrahedral material with an orthorhombic unit cell (a = 14.522 Ǻ, b = 12.469 Ǻ, and c = 10.654 Ǻ). 119Sn single-pulse MAS NMR results presented two resonance lines, at δ1 = -683.8 ppm and δ2 = -690.9 ppm, which were assigned to the tin octahedrally coordinated in the metallo-stannosilicate structure. Heterogenous catalytic studies in the transesterification of refined edible, non-edible, and waste oils have resulted in high yields of FAMEs and FAEEs (fatty acid methyl and ethyl esters), nevertheless the highest FAMES (98.2%) and FAEEs (96.6%) yields were obtained for non-edible microalgae oil extracted from the genetically modified heterotrophic algal strain Prototheca moriformis. Catalytic studies also using non-edible macaw palm oil (Acrocomia aculeata) with a high content of free fatty acids (FFAs) demonstrated that the catalyst could simultaneously perform esterification and transesterification reactions. These findings indicate the potential application of this novel metallo-stannosilicate in the production of renewable and environmentally clean biofuels, like biodiesel, using different sources of lipids feedstocks, notably those that do not compete with food production.
Forage sorghum (Sorghum bicolor L.) has been grown in diverse climate variations, in warm and dry regions, or in regions with short drought periods. Thus, there is a need to select sorghum genotypes ...adapted to production systems under drought or rainy irregularities. This study evaluated the direct and indirect correlations among morphophysiological and productive characters of forage sorghum genotypes with Pearson’s correlation and path analysis. The experiment was designed under complete randomized blocks, with 25 treatments (genotypes) and three replicates. Analyzes of phenotypic correlation and the path analysis were done for plant height, panicle length, stem diameter, plant stand, green matter and dry matter yields, stem weight, plant weight, panicle weight, dry matter content, and forage mass. Plant weight presented the most significant direct effect on the forage mass (target variable), contributing to the increase in forage sorghum production. Therefore, heavier plants are more suitable to select forage sorghum genotypes indirectly, aiming to increase forage mass.
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