To identify factors associated with granting or refusing intensive care unit (ICU) admission, to analyze ICU characteristics and triage decisions, and to describe mortality in admitted and refused ...patients.
Observational, prospective, multiple-center study.
Four university hospitals and seven primary-care hospitals in France.
None.
Age, underlying diseases (McCabe score and Knaus class), dependency, hospital mortality, and ICU characteristics were recorded. The crude ICU refusal rate was 23.8% (137/574), with variations from 7.1% to 63.1%. The reasons for refusal were too well to benefit (76/137, 55.4%), too sick to benefit (51/137, 37.2%), unit too busy (9/137, 6.5%), and refusal by the family (1/137). In logistic regression analyses, two patient-related factors were associated with ICU refusal: dependency (odds ratio OR, 14.20; 95% confidence interval CI, 5.27-38.25; p < .0001) and metastatic cancer (OR, 5.82; 95% CI, 2.22-15.28). Other risk factors were organizational, namely, full unit (OR, 3.16; 95% CI, 1.88-5.31), center (OR, 3.81; 95% CI, 2.27-6.39), phone admission (OR, 0.23; 95% CI, 0.14-0.40), and daytime admission (OR, 0.52; 95% CI, 0.32-0.84). The Standardized Mortality Ratio was 1.41 (95% CI, 1.19-1.69) for immediately admitted patients, 1.75 (95% CI, 1.60-1.84) for refused patients, and 1.03 (95% CI, 0.28-1.75) for later-admitted patients.
ICU refusal rates varied greatly across ICUs and were dependent on both patient and organizational factors. Efforts to define ethically optimal ICU admission policies might lead to greater homogeneity in refusal rates, although case-mix variations would be expected to leave an irreducible amount of variation across ICUs.
Measurement-based quantum error correction relies on the ability to determine the state of a subset of qubits (ancillas) within a processor without revealing or disturbing the state of the remaining ...qubits. Among neutral-atom-based platforms, a scalable, high-fidelity approach to midcircuit measurement that retains the ancilla qubits in a state suitable for future operations has not yet been demonstrated. In this work, we perform maging using a narrow-linewidth transition in an array of tweezer-confined ^{171}Yb atoms to demonstrate nondestructive state-selective and site-selective detection. By applying site-specific light shifts, selected atoms within the array can be hidden from imaging light, which allows a subset of qubits to be measured while causing only percent-level errors on the remaining qubits. As a proof-of-principle demonstration of conditional operations based on the results of the midcircuit measurements, and of our ability to reuse ancilla qubits, we perform conditional refilling of ancilla sites to correct for occasional atom loss, while maintaining the coherence of data qubits. Looking toward true continuous operation, we demonstrate loading of a magneto-optical trap with a minimal degree of qubit decoherence.
Assembling and maintaining large arrays of individually addressable atoms is a key requirement for continued scaling of neutral-atom-based quantum computers and simulators. In this work, we ...demonstrate a new paradigm for assembly of atomic arrays, based on a synergistic combination of optical tweezers and cavity-enhanced optical lattices, and the incremental filling of a target array from a repetitively filled reservoir. In this protocol, the tweezers provide microscopic rearrangement of atoms, while the cavity-enhanced lattices enable the creation of large numbers of optical traps with sufficient depth for rapid low-loss imaging of atoms. We apply this protocol to demonstrate near-deterministic filling (99% per-site occupancy) of 1225-site arrays of optical traps. Because the reservoir is repeatedly filled with fresh atoms, the array can be maintained in a filled state indefinitely. We anticipate that this protocol will be compatible with mid-circuit reloading of atoms into a quantum processor, which will be a key capability for running large-scale error-corrected quantum computations whose durations exceed the lifetime of a single atom in the system.
Measurement-based quantum error correction relies on the ability to determine the state of a subset of qubits (ancillae) within a processor without revealing or disturbing the state of the remaining ...qubits. Among neutral-atom based platforms, a scalable, high-fidelity approach to mid-circuit measurement that retains the ancilla qubits in a state suitable for future operations has not yet been demonstrated. In this work, we perform imaging using a narrow-linewidth transition in an array of tweezer-confined \(^{171}\)Yb atoms to demonstrate nondestructive state-selective and site-selective detection. By applying site-specific light shifts, selected atoms within the array can be hidden from imaging light, which allows a subset of qubits to be measured while causing only percent-level errors on the remaining qubits. As a proof-of-principle demonstration of conditional operations based on the results of the mid-circuit measurements, and of our ability to reuse ancilla qubits, we perform conditional refilling of ancilla sites to correct for occasional atom loss, while maintaining the coherence of data qubits. Looking towards true continuous operation, we demonstrate loading of a magneto-optical trap with a minimal degree of qubit decoherence.
The book presents the state of the art and results and also includes articles pointing to future developments. Most of the articles center around the theme of linear partial differential equations. ...Major aspects are fast solvers in elastoplasticity, symbolic analysis for boundary problems, symbolic treatment of operators, computer algebra, and finite element methods, a symbolic approach to finite difference schemes, cylindrical algebraic decomposition and local Fourier analysis, and white noise analysis for stochastic partial differential equations. Further numerical-symbolic topics range from applied and computational geometry to computer algebra methods used for total variation energy minimization.
THE JULY 1960 issue of Esquire—dedicated to New York—featured consecutive essays by the writers John Cheever and James Baldwin. “Moving Out” features Cheever grappling with his decision to leave the ...city for good; he ends by proclaiming himself “crazy about the suburbs.” Baldwin’s “Fifth Avenue, Uptown,” a sobering counterpoint, sketches contained and constricted black populations: “The people in Harlem know they are living there because white people do not think they are good enough to live anywhere else.” Baldwin links Harlem’s ongoing stagnation to Cheever’s “evacuation.” Both Cheever’s and Baldwin’s cognitive maps, though, omit the small Brooklyn enclave
Christopher T. Paule is President and CEO of Jackson Products, Inc. (JPI), Chesterfield, MO, an international manufacturer and distributor of personal and highway safety products. JPI recently ...introduced the NexGen EQC welding helmet-a new line of auto-darkening helmets that was developed, based on input from JPI's customers.
Christopher T. Paule is President and CEO of Jackson Products, Inc. (JPI), Chesterfield, MO, an international manufacturer and distributor of personal and highway safety products. JPI recently ...introduced the NexGen EQC welding helmet-a new line of auto-darkening helmets that was developed, based on input from JPI's customers.