ScIrP with ZrNiAl-type Structure Pfannenschmidt, U.; Rodewald, U. Ch; Pöttgen, R.
Zeitschrift für Naturforschung. B, A journal of chemical sciences,
02/2011, Letnik:
66
Journal Article
Abstract Background NASH (non-alcoholic steatohepatitis) is considered the hepatic manifestation of the metabolic syndrome (MS). We aimed to analyze lipid, carbohydrate, and iron metabolism in NASH. ...Patients, methods 37 patients with MS (17 M/20 F, 51 +/− 15 years), elevated transaminases; 25 patients had histologically proven NASH (NAS score ≥ 5), 12 patients had toxic background (nonNASH). 37 age, sex, BMI-matched healthy controls. Lipid variables, LDL-subfractions, iron, ferritin, transferrin (T), transferrin saturation (TS), and hepcidin (H) were measured in patients/controls. Oral glucose tolerance tests were performed. Results NASH patients with steatosis gr. 2 and 3 (> 33% hepatic fat) had higher sd-LDL (mg/dl) concentrations than patients with steatosis gr. 1 (< 33%) (p = 0.002), nonNASH patients (p = 0.03) and controls (p = 0.001). Sd absolute (mg/dl) correlated directly with the steatosis grade only in patients with NASH and steatosis > 33% (p = 0.04). NASH-patients showed higher insulin, C-peptide and IRI values than nonNASH patients (p = 0.034; 0.032; 0.04). H was increased in patients versus controls (p < 0.001). H correlated with ferritin in MS-patients (p = 0.01), correlated directly with sd-LDL (mg/dl) (p = 0.017) and IRI (p < 0.001) and indirectly with HDL (p = 0.05) in NASH. No associations between hepatic inflammation/iron content on liver biopsy and variables of lipid metabolism were found but hepcidin correlated with hepatic inflammation in all patients and with NAS scores in NASH. Conclusions NASH-patients show insulin resistance and increased sd-LDL subfractions, suggesting an atherogenic profile. The correlation of H with sd-LDL and IRI, without relation to hepatic iron content suggests a putative link between inflammation, carbohydrate and lipid metabolism in NASH.
SrAu4.76In1.24 with YbMo2Al4-type Structure Muts, I.; Matar, S. F.; Rodewald, U. Ch ...
Zeitschrift für Naturforschung. B, A journal of chemical sciences,
10/2011, Letnik:
66
Journal Article
The Metal-rich Phosphide Ce4Ir13.55P9 Pfannenschmidt, U.; Rodewald, U. Ch; Pöttgen, R.
Zeitschrift für Naturforschung. B, A journal of chemical sciences,
2011, Letnik:
66
Journal Article
Synthesis and Structures of SrAuIn and SrAuIn3 Muts, Ihor R.; Pöttgen, Rainer; Zaremba, Vasyl I.
Zeitschrift für anorganische und allgemeine Chemie (1950),
November 2007, Letnik:
633, Številka:
15
Journal Article
Recenzirano
The intermetallic compounds SrAuIn and SrAuIn3 were synthesised from the elements in sealed tantalum ampoules in a high‐frequency furnace. Both indides were studied by X‐ray powder and single crystal ...diffraction: TiNiSi type, Pnma, a = 772.2(4), b = 478.6(2), c = 844.0(4) pm, wR2 = 0.0474, 748 F2 values, 20 variables for SrAuIn and BaNiSn3 type, I4mm, a = 456.97(8), c = 1243.7(3) pm, wR2 = 0.0381, 397 F2 values, 18 variables for SrAuIn3. The latter reveals a small degree of Au/In disorder. Both structures consist of three‐dimensional AuIn, respectively AuIn3 polyanionic networks with short Au–In distances (287–291 pm in SrAuIn and 268–284 pm in SrAuIn3. The latter indide reveals also In–In bonding (294–323 pm). The larger voids within the polyanionic networks of both structures are filled by the strontium cations.
