Diabetic Optical Neuropathy (DON) is the optical nerve damage induced by the Diabetes Mellitus. Optical nerve sufferings in Diabetes Mellitus were studied much less compare to the retinal changes. ...But according to the literature data, the DON has been detected in 7 to 24.3% of Diabetes Mellitus patients. That's why the investigators great interest refers to the optical nerve pathological changes pathways in Diabetes Mellitus studying. This article was focused to the up-to-date scientific views of the DON pathogenesis summarizing. Two basic ways of the DON pathogenesis were demonstrated: metabolic and vascular. The metabolic pathway was connected with the neural tissue damage induced by the diabetic changed metabolism. The vascular pathway was connected with the ischemia and endoneural blood flow malfunction.
Virtual 3D models were made on the stages of prosthodontic treatment by upper complete dentures. Anthropometric points were marked on the lower third of the face and soft tissue contour changed were ...studied. The study results showed the vestibular surface of the occlusion rim may be used for computer design of removable complete dentures.
The active development and introduction of CAD/CAM technologies in dental practice initiated the authors (of the article) to develop the algorithm of virtual set up of complete removable prostheses ...using 3D visualization system of face and dentitions. Patient's faces and individual tablespoon with occlusal rollers were scanning. Three-dimensional models ware received on. Then both models were put in correspondence with each other by software RapidForm 2006 Basis . Virtual artificial teeth were selected from computerized databank.
The clinical isolates of Staphylococcus aureus (n = 102) were analyzed on sensitivity and to gentamicin, tobramicin, netimicin and amikacin. The disc diffusing technique was applied. The technique ...ofpolymerase chain reaction was applied to analyze all strains establishing presence in their genomes genes aac (6'-Ie/aph(2"), ant1, aac, ant(6)-Ia, aph (3')-IIIa and ant(4')-Ia coding amino-glycoside-modifying enzymes. The strains sensitive to amino-glycosides had no the given genes in genome. The genome of all strains resistant to amino-glycosides included no less than two of enumerated genes. The 100% correlation was established between phenotypic resistance of analyzed strains to amino-glycosides and availability in them of gene aac(6')-Ie/aph(2").
Antiplaque/antigingivitis effect of an alcohol-free mouthrinse Parodontocid were evaluated by randomized parallel group clinical trial. Sixty patients with gingivitis were clinically examined to ...determine PHP, RMNPI and PMA indexes. After professional dental prophylaxis, subjects were randomly assigned in two groups to 10 days oral hygiene program. Group 1 patients used only toothbrush and prophylactic toothpaste while in group 2 persons used Parodontocid in conjunction with normal brushing and flossing.Parodontocid significantly reduced plaque and gingivitis compared to negative control.
Molecular analysis of Streptococcus pyogenes types emm1 and emm12 genomes on the presence of genes belonging to prophage DNA.
Thirty-one strains of S. pyogenes type emm1 and 22 strains of S. pyogenes ...type emm12 were objects of the study. Polymerase chain reaction with special primers for detection of 24 phage genes was used in the study.
Prevalence of phage genes in strains of different emm types was assessed. The following phage genes were most frequently detected: speA, speC, ssa genes for emm1 type and speC and speH for emm12 type. On the basis of the study, 19 different profiles of phage genes were identified.
The study allowed to identify not only differences but also similarities between strains of emm1 and emm12 types on prophage gene repertoire in bacterial genome. Presence of similarities allows to assume the possibility of circulation in the studied region similar or identical bacteriophages between streptococci group A (SGA) strains of different emm types.
Based upon analysis of postoperative morbidity the authors concluded that salivary glands extirpation led to considerably often development of different gastrointestinal tract diseases in comparison ...with other operative interventions. The most often (62%) these diseases appeared in patients with submandibular salivary gland removal in anamnesis and rarer (21%) - with parotid salivary gland removal. So it could be claimed that salivary glands were an important constituent part of digestive system. Salivary glands removal was only proper in case of impossibility of carrying organ preserving operative intervention.
Thirteen healthy individuals and 27 patients with diabetic retinopathy were examined (23 patients (23 eyes) with diabetic retinopathy being selected for analysis). The proposed indicator of optic ...nerve head (ONH) edema from the data of optical coherence tomography could more frequently diagnose asymptomatic ONH edema due to the detection of its early forms on 5 of the 23 eyes versus 3 eyes, as evidenced by biomicroophthalmoscopy (slit-lamp ophthalmoscopy). The patients were found to have a drastic reduction in the level of brain-derived neutrotrophic factor (BDNF) in plasma and lacrimal fluid. The most marked decrease in plasma BDNF was observed in patients with asymptomatic ONH edema. The tear content of BDNF was particularly low in patients with increased neuroretinal rim volume.
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