We investigate the relationship between colour and structure within galaxies using a large, volume-limited sample of bright, low-redshift galaxies with optical–near-infrared imaging from the Galaxy ...And Mass Assembly survey. We fit single-component, wavelength-dependent, elliptical Sérsic models to all passbands simultaneously, using software developed by the MegaMorph project. Dividing our sample by n and colour, the recovered wavelength variations in effective radius (R
e) and Sérsic index (n) reveal the internal structure, and hence formation history, of different types of galaxies. All these trends depend on n; some have an additional dependence on galaxy colour. Late-type galaxies (n
r
< 2.5) show a dramatic increase in Sérsic index with wavelength. This might be a result of their two-component (bulge–disc) nature, though stellar population gradients within each component and dust attenuation are likely to play a role. All galaxies show a substantial decrease in R
e with wavelength. This is strongest for early types (n
r
> 2.5), even though they maintain constant n with wavelength, revealing that ellipticals are a superimposition of different stellar populations associated with multiple collapse and merging events. Processes leading to structures with larger R
e must be associated with lower metallicity or younger stellar populations. This appears to rule out the formation of young cores through dissipative gas accretion as an important mechanism in the recent lives of luminous elliptical galaxies.
The antimicrobial resistance (AMR) of
recorded a steep upward trend over the last two decades, among which carbapenem-resistant
(CRKP) is one of the most concerning strains considering the ...development and spread of AMR. The aim of this study was to analyze the evolution of AMR for
and to describe the risk factors of AMR for
, including the COVID-19 pandemic.
We conducted a retrospective study on
non-duplicative isolates collected from patients admitted to a tertiary hospital in Bucharest, Romania, from January 2019 to December 2021. We evaluated AMR changes by comparing resistance between 2019 and the mean of 2020-2021.
The rates of AMR increased for third-generation cephalosporins, carbapenems, aminoglycosides, fluoroquinolones, and colistin and decreased for trimethoprim/sulfamethoxazole (TMP/SMX), 45.7% in 2019 vs. 28.3% in 2021. A longer length of hospital stay (ꭓ
= 49.68,
< 0.01); recent antibiotic consumption, RR = 1.38, 95% CI 1.21, 1.57; and recent contact with hospital settings, RR = 1.54, 95% CI 1.32, 1.8 were risk factors for multidrug-resistant (MDR)
.
The AMR of
increased during 2020-2021 for most of the potential active antibiotics; only TMP/SMX resistance decreased, and it may represent a treatment option for CRKP or MDR
infections. Decreasing the excessive use of antibiotics and the implementation of prevention and control measures in healthcare settings are mandatory for avoiding further increases in the AMR rate of
.
We provide and describe a library of diffuse stellar radiation fields in spiral galaxies derived using calculations of the transfer of stellar radiation from the main morphological components - ...discs, thin discs and bulges - through the dusty interstellar medium. These radiation fields are self-consistent with the solutions for the integrated panchromatic spectral energy distributions (SEDs) previously presented using the same model. Because of this, observables calculated from the radiation fields, such as gamma-ray or radio emission, can be self-consistently combined with the solutions for the ultraviolet/optical/submillimetre SEDs, thus expanding the range of applicability of the radiation transfer model to a broader range of wavelengths and physical quantities. We also give analytic solutions for radiation fields in optically thin stellar discs, in stellar discs with one dust disc and in stellar discs with two dust discs. The analytic solutions for the direct light are exact and can be used as benchmarks. The analytic solutions with scattering are only approximate, becoming exact only in the extreme optically thick limit. We find strongly contrasting solutions for the spatial distribution of the radiation fields for discs, thin discs and bulges. For bulges, we find a strong dependence of the radiation fields on the Sérsic index.
In order to generate credible 0.1-2 μm spectral energy distributions, the Galaxy and Mass Assembly (GAMA) project requires many gigabytes of imaging data from a number of instruments to be ...reprocessed into a standard format. In this paper, we discuss the software infrastructure we use, and create self-consistent ugrizYJHK photometry for all sources within the GAMA sample. Using UKIDSS and SDSS archive data, we outline the pre-processing necessary to standardize all images to a common zero-point, the steps taken to correct for the seeing bias across the data set and the creation of gigapixel-scale mosaics of the three 4 × 12 deg2 GAMA regions in each filter. From these mosaics, we extract source catalogues for the GAMA regions using elliptical Kron and Petrosian matched apertures. We also calculate Sérsic magnitudes for all galaxies within the GAMA sample using sigma, a galaxy component modelling wrapper for galfit 3. We compare the resultant photometry directly and also calculate the r-band galaxy luminosity function for all photometric data sets to highlight the uncertainty introduced by the photometric method. We find that (1) changing the object detection threshold has a minor effect on the best-fitting Schechter parameters of the overall population (M*± 0.055 mag, α± 0.014, ϕ*± 0.0005 h
3 Mpc−3); (2) there is an offset between data sets that use Kron or Petrosian photometry, regardless of the filter; (3) the decision to use circular or elliptical apertures causes an offset in M* of 0.20 mag; (4) the best-fitting Schechter parameters from total-magnitude photometric systems (such as SDSS modelmag or Sérsic magnitudes) have a steeper faint-end slope than photometric systems based upon Kron or Petrosian measurements; and (5) our Universe's total luminosity density, when calculated using Kron or Petrosian r-band photometry, is underestimated by at least 15 per cent.
Abundant experimental data suggest that hydrogen sulfide (H2S) is related to the pathophysiology of Diabetes Mellitus (DM). Multiple molecular mechanisms, including receptors, membrane ion channels, ...signalingmolecules, enzymes, and transcription factors, are known to be responsible for the H2S biological actions; however, H2S is not fully documented as a gaseous signaling molecule interfering with DM and vascular-linked pathology. In recent decades, multiple approaches regarding therapeutic exploitation of H2S have been identified, either based on H2S exogenous apport or on its modulated endogenous biosynthesis. This paper aims to synthesize and systematize, as comprehensively as possible, the recent literature-related data regarding the therapeutic/rehabilitative role of H2S in DM. This review was conducted following the “Preferred reporting items for systematic reviews and meta-analyses” (PRISMA) methodology, interrogating five international medically renowned databases by specific keyword combinations/“syntaxes” used contextually, over the last five years (2017–2021). The respective search/filtered and selection methodology we applied has identified, in the first step, 212 articles. After deploying the next specific quest steps, 51 unique published papers qualified for minute analysis resulted. To these bibliographic resources obtained through the PRISMA methodology, in order to have the best available information coverage, we added 86 papers that were freely found by a direct internet search. Finally, we selected for a connected meta-analysis eight relevant reports that included 1237 human subjects elicited from clinical trial registration platforms. Numerous H2S releasing/stimulating compounds have been produced, some being used in experimental models. However, very few of them were further advanced in clinical studies, indicating that the development of H2S as a therapeutic agent is still at the beginning.
This paper reports the morphological and thermal characterization of xanthan/lignin hydrogels. It has been emphasized the effect of the lignin type on the hydrogel properties. The hydrogels described ...here were obtained by chemical crosslinking, in the presence of epichlorohydrine as a cross-linker agent. The obtained materials were analyzed by AFM, TG/DTG, DSC, and FT-IR spectroscopy. It has been established that hydrogels have a porous morphology. The lignin type influences the hydrogel morphology which is either fibrilar as in case of hydrogel containing aspen wood lignin (which has the highest content of COOH groups and lowest content of phenolic OH groups) or smooth surface for other hydrogels. The specific intermolecular interactions are stronger in the case of 70 xanthan (X)/30 aspen wood lignin (AWL) hydrogel. The thermal properties of the hydrogels also depend on lignin type, the lowest thermal stability being found for the hydrogel containing lignin with the highest content of functional groups (AWL).
We describe the calculation of the stochastically heated dust emission using the 3D ray-tracing dust radiative transfer code dart-ray, which is designed to solve the dust radiative transfer problem ...for galaxies with arbitrary geometries. In order to reduce the time required to derive the non-equilibrium dust emission spectra from each volume element within a model, we implemented an adaptive spectral energy distribution library approach, which we tested for the case of axisymmetric galaxy geometries. To show the capabilities of the code, we applied dart-ray to a high-resolution N-body+SPH galaxy simulation to predict the appearance of the simulated galaxy at a set of wavelengths from the UV to the sub-mm. We analyse the results to determine the effect of dust on the observed radial and vertical profiles of the stellar emission as well as on the attenuation and scattering of light from the constituent stellar populations. We also quantify the proportion of dust re-radiated stellar light powered by young and old stellar populations, both bolometrically and as a function of infrared wavelength.
We look for correlated changes in stellar mass and star formation rate (SFR) along filaments in the cosmic web by examining the stellar masses and UV-derived SFRs of 1799 ungrouped and unpaired ...spiral galaxies that reside in filaments. We devise multiple distance metrics to characterize the complex geometry of filaments, and find that galaxies closer to the cylindrical centre of a filament have higher stellar masses than their counterparts near the periphery of filaments, on the edges of voids. In addition, these peripheral spiral galaxies have higher SFRs at a given mass. Complementing our sample of filament spiral galaxies with spiral galaxies in tendrils and voids, we find that the average SFR of these objects in different large-scale environments are similar to each other with the primary discriminant in SFR being stellar mass, in line with previous works. However, the distributions of SFRs are found to vary with large-scale environment. Our results thus suggest a model in which in addition to stellar mass as the primary discriminant, the large-scale environment is imprinted in the SFR as a second-order effect. Furthermore, our detailed results for filament galaxies suggest a model in which gas accretion from voids on to filaments is primarily in an orthogonal direction. Overall, we find our results to be in line with theoretical expectations of the thermodynamic properties of the intergalactic medium in different large-scale environments.
In the rapidly evolving field of Alzheimer’s Disease (AD) research, the intricate role of Hydrogen Sulfide (H2S) has garnered critical attention for its diverse involvement in both pathological ...substrates and prospective therapeutic paradigms. While conventional pathophysiological models of AD have primarily emphasized the significance of amyloid-beta (Aβ) deposition and tau protein hyperphosphorylation, this targeted systematic review meticulously aggregates and rigorously appraises seminal contributions from the past year elucidating the complex mechanisms of H2S in AD pathogenesis. Current scholarly literature accentuates H2S’s dual role, delineating its regulatory functions in critical cellular processes—such as neurotransmission, inflammation, and oxidative stress homeostasis—while concurrently highlighting its disruptive impact on quintessential AD biomarkers. Moreover, this review illuminates the nuanced mechanistic intimate interactions of H2S in cerebrovascular and cardiovascular pathology associated with AD, thereby exploring avant-garde therapeutic modalities, including sulfurous mineral water inhalations and mud therapy. By emphasizing the potential for therapeutic modulation of H2S via both donors and inhibitors, this review accentuates the imperative for future research endeavors to deepen our understanding, thereby potentially advancing novel diagnostic and therapeutic strategies in AD.
We explore trends in galaxy properties with Mpc-scale structures using catalogues of environment and large-scale structure from the Galaxy And Mass Assembly (GAMA) survey. Existing GAMA catalogues of ...large-scale structure, group, and pair membership allow us to construct galaxy stellar mass functions for different environmental types. To avoid simply extracting the known underlying correlations between galaxy properties and stellar mass, we create a mass matched sample of galaxies with stellar masses within 9.5 ≤ log M
*/h
−2 M⊙ ≤ 11 for each environmental population. Using these samples, we show that mass normalized galaxies in different large-scale environments have similar energy outputs, u − r colours, luminosities, and morphologies. Extending our analysis to group and pair environments, we show that galaxies that are not in groups or pairs exhibit similar characteristics to each other regardless of broader environment. For our mass controlled sample, we fail to see a strong dependence of Sérsic index or galaxy luminosity on halo mass, but do find that it correlates very strongly with colour. Repeating our analysis for galaxies that have not been mass controlled introduces and amplifies trends in the properties of galaxies in pairs, groups, and large-scale structure, indicating that stellar mass is the most important predictor of the galaxy properties we examine, as opposed to environmental classifications.