Due to their simplicity and versatility of design, straight strip or rectangular pad anode structures are frequently used with micropattern gas detectors (MPGDs) to reconstruct high-precision space ...points for various tracking applications. The particle impact point is typically determined by interpolating the charge collected by several neighboring strips. However, to effectively extract the inherent positional information, the lateral spacing of the straight strips must be comparable to or preferably smaller than the full extent of the incident charge cloud. In contrast, highly interleaved anode patterns, such as zigzags, can adequately sample the incident charge with a pitch appreciably larger than the charge cloud. This has the considerable advantage of providing the same performance while requiring far fewer instrumented channels. Additionally, the geometric parameters defining such zigzag structures may be tuned to provide a near-uniform detector response along and perpendicular to the sensitive coordinate, without the need for so-called "pad response functions," while simultaneously maintaining excellent position resolution. We have measured the position resolution of a variety of zigzag-shaped anode patterns optimized for various MPGDs, including gas electron multiplyer (GEM), Micromegas, and micro-resistive-well (<inline-formula> <tex-math notation="LaTeX">\mu </tex-math></inline-formula>RWELL) and compared this performance with the same detectors equipped with straight strips of varying pitch. We report on the performance results of each readout structure, evaluated under identical conditions in a test beam.
We have developed highly interleaved zigzag-shaped electrodes for collecting charge on the readout plane of various micropattern gaseous detectors (MPGDs), including gas electron multiplier (GEM) and ...micromega detectors. An optimized zigzag pad (or strip) anode can greatly enhance charge sharing among neighboring pads compared to traditional straight strip or rectangular pad designs and as a result can deliver excellent position resolution with minimal channel count, while exhibiting a virtually uniform response across the detector. We have systematically studied the effects of varying the parameters that define the zigzag geometry using simulations and have measured several printed circuit boards (PCBs) comprising a range of zigzag designs. Recently, we have employed laser ablation to generate zigzag patterns with pad-to-pad gaps smaller than 1 mil (or 25 <inline-formula> <tex-math notation="LaTeX">\mu \text{m} </tex-math></inline-formula>). Reducing the gap well below the 3-mil limit imposed by traditional chemical etching has allowed the production of zigzag electrodes with unprecedentedly small feature sizes. In turn, laser-etched zigzag PCBs were shown to exhibit markedly improved performance over earlier generation PCBs, with position resolutions below 50 <inline-formula> <tex-math notation="LaTeX">\mu \text{m} </tex-math></inline-formula> for a 2-mm pitch. This article will explore in detail the dependence of the position resolution on the structural parameters of a zigzag-shaped anode, specifically for the case of a quadruple GEM detector.
New design studies have been carried out for a readout plane for gas electron multiplier detectors using zigzag patterns that can significantly reduce the readout channel count while preserving ...excellent spatial resolution for tracking detectors. While zigzag patterns have been used in a number of applications, these studies were designed to investigate the fundamental limits of charge sharing between the electrodes to optimize the spatial resolution and minimize the nonuniformities across the readout plane, while exploring the limits of manufacturing capabilities for producing the readout board. Simulation studies were carried out to optimize the readout electrode structure, and readout boards were produced with similar zigzag designs that were tested in the laboratory using a scanning X-ray source. These studies were aimed at developing a readout board for the new time projection chamber for the sPHENIX experiment at relativistic heavy ion collider, but can readily be used in other applications, including various micropattern gas detectors, such as Micromegas.
The super Pioneering High Energy Nuclear Interaction eXperiment (sPHENIX) at the Relativistic Heavy Ion Collider will perform high-precision measurements of jets and heavy flavor observables for a ...wide selection of nuclear collision systems, elucidating the microscopic nature of strongly interacting matter ranging from nucleons to the strongly coupled quark-gluon plasma. A prototype of the sPHENIX calorimeter system was tested at the Fermilab Test Beam Facility as experiment T-1044 in the spring of 2016. The electromagnetic calorimeter (EMCal) prototype is composed of scintillating fibers embedded in a mixture of tungsten powder and epoxy. The hadronic calorimeter (HCal) prototype is composed of tilted steel plates alternating with the plastic scintillator. Results of the test beam reveal the energy resolution for electrons in the EMCal is <inline-formula> <tex-math notation="LaTeX">2.8\%\oplus 15.5\%/\sqrt {E} </tex-math></inline-formula> and the energy resolution for hadrons in the combined EMCal plus HCal system is <inline-formula> <tex-math notation="LaTeX">13.5\%\oplus 64.9\%/\sqrt {E} </tex-math></inline-formula>. These results demonstrate that the performance of the proposed calorimeter system satisfies the sPHENIX specifications.
A combined time projection chamber-Cherenkov (TPCC) prototype detector has been developed as part of the detector research and development program for a future electron-ion collider (EIC). The ...prototype was tested at the Fermilab test beam facility (FTBF) to provide a proof of the principle to demonstrate the ability to measure particle tracks and provide particle identification (PID) information within a common detector volume. The time projection chamber (TPC) portion consists of a <inline-formula> <tex-math notation="LaTeX">10 \times 10 \times 10 </tex-math></inline-formula> cm 3 field cage, which delivers charge from tracks to a quadruple gas electron multiplier (GEM) with zigzag-shaped charge collection anodes. The Cherenkov portion consists of a photosensitive quadruple GEM detector with a CsI photocathode. As tracks pass through the drift volume of the TPC, the generated Cherenkov light is able to escape through sparsely arranged wires making up one side of the field cage, facing the CsI photocathode. The Cherenkov detector is thus operated in a windowless, proximity focused configuration for high efficiency. Pure CF 4 is used as the working gas for both detector components, mainly due to its transparency into the deep UV, as well as its high N 0 . Results from the beam test, including the position resolution as well as the particle id capabilities of the detector, are discussed in this paper.
sPHENIX is a new experiment under construction for the Relativistic Heavy Ion Collider at Brookhaven National Laboratory which will study the quark-gluon plasma to further the understanding of ...quantum chromodynamics (QCP) matter and interactions. A prototype of the sPHENIX electromagnetic calorimeter (EMCal) was tested at the Fermilab Test Beam Facility in Spring 2018 as experiment T-1044. The EMCal prototype corresponds to a solid angle of <inline-formula> <tex-math notation="LaTeX">\Delta \eta \times \Delta \phi = 0.2 \times 0.2 </tex-math></inline-formula> centered at pseudo-rapidity <inline-formula> <tex-math notation="LaTeX">\eta = 1 </tex-math></inline-formula>. The prototype consists of scintillating fibers embedded in a mix of tungsten powder and epoxy. The fibers project back approximately to the center of the sPHENIX detector, giving 2-D projectivity. The energy response of the EMCal prototype was studied as a function of position and input energy. The energy resolution of the EMCal prototype was obtained after applying a position-dependent energy correction and a beam profile correction. Two separate position-dependent corrections were considered. The EMCal energy resolution was found to be <inline-formula> <tex-math notation="LaTeX">\sigma (E)/\langle E\rangle = 3.5(0.1) \oplus 13.3(0.2)/\sqrt {E} </tex-math></inline-formula> based on the hodoscope position-dependent correction, and <inline-formula> <tex-math notation="LaTeX">\sigma (E)/\langle E\rangle = 3.0(0.1) \oplus 15.4(0.3)/\sqrt {E} </tex-math></inline-formula> based on the cluster position-dependent correction. These energy resolution results meet the requirements of the sPHENIX physics program.
A GEM tracking detector with an extended drift region has been studied as part of an effort to develop new tracking detectors for future experiments at RHIC and for the Electron Ion Collider that is ...being planned for BNL or JLAB. The detector consists of a triple GEM stack with a 1.6 cm drift region that was operated in a mini TPC type configuration. Both the position and arrival time of the charge deposited in the drift region were measured on the readout plane which allowed the reconstruction of a short vector for the track traversing the chamber. The resulting position and angle information from the vector could then be used to improve the position resolution of the detector for larger angle tracks, which deteriorates rapidly with increasing angle for conventional GEM tracking detectors using only charge centroid information. Two types of readout planes were studied. One was a COMPASS style readout plane with 400 μm pitch XY strips and the other consisted of 2 × 10 mm 2 chevron pads. The detector was studied in test beams at Fermilab and CERN, along with additional measurements in the lab, in order to determine its position and angular resolution for incident track angles up to 45 degrees. Several algorithms were studied for reconstructing the vector using the position and timing information in order to optimize the position and angular resolution of the detector for the different readout planes. Applications for large angle tracking detectors at RHIC and EIC are also discussed.
Positron Emission Tomography is a powerful imaging technique used for humans and animals that can also be used to study plant biology. However, since many of the structures found on plants (e.g., ...leaves) are very thin, a large portion of the positrons emitted from PET isotopes escape before annihilation, leading to low efficiency and quantification inaccuracies. In this study, a gas tracking detector was used to measure escaping positrons from PET radiotracer isotopes which has the ability to reconstruct three dimensional tracks that can be used to form an image of the emitting object. This device uses a triple GEM detector with a short drift region and an XY strip readout plane to measure a vector for positrons passing through a drift gap. By projecting each particle track back to the object surface, a 2-D image of the spatial distribution of the positrons that escaped from that surface can be reconstructed. In this paper, we will describe the basic principle of the GEM detector and present results on its performance using various types of phantoms and actual plant specimens. Monte Carlo simulations are also used to better understand the detector performance and compare to actual measurements.
Summary
Background
Epidermal suction blister grafts are an effective treatment for chronic wounds or vitiligo, but this treatment is time consuming and limited to small areas.
Objectives
To compare ...two novel strategies to create fractional epidermal grafts.
Methods
Epidermal blisters were raised from fresh human skin ex vivo at 38–40 °C, with suction of 380–510 mmHg. In Strategy 1, a 1‐cm blister was micromeshed into approximately 500 pieces, transferred to elastic adhesive dressing, then pneumatically expanded to approximately nine times the original blister area. In Strategy 2, a 25‐cm2 array of 100 small blisters was raised, simultaneously harvested and captured directly onto an adhesive dressing. Measurements were taken for the pneumatic expansion limit, the release of microblisters upon hydration of the dressing adhesive, light microscopy, epidermal cell viability and positive L‐3,4 dihydroxyphenylalanine melanocyte presence in blisters.
Results
Both strategies yielded viable fractional epidermal microblister arrays, carried on a dressing for transfer to graft recipient sites. The microblisters were gradually released upon hydration of the dressing adhesive. Strategy 2 has major advantages as only small blisters are made at the donor site, skilful dissection and physical expansion are not required and the strategy can be scaled to create large‐area grafts.
Conclusions
Strategy 2 is the more practical method for fractional epidermal micrografting to treat larger lesions with less donor‐site trauma and has recently been commercialized.
What's already known about this topic?
Current treatments for vitiligo and chronic wounds are often not very effective and unsatisfying for patients.
Conventional epidermal blister grafting is one treatment option for chronic vitiligo, but is time consuming, limited to small areas and requires surgical skill.
What does this study add?
Novel fractional epidermal micrografting is a promising alternative treatment for vitiligo and chronic wounds with fewer side‐effects to donor and receptor sites and has the advantage of treating larger lesions.
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