Ecoprint is a technique for printing colors and shapes on fabric using natural materials. Ecoprint techniques have been introduced to junior high school students because they can capture the material ...and teacher's instructions independently, think critically and creatively. The purpose of the ecoprint introduction activity is to provide knowledge about ecoprint and students' skills in utilizing local potential through natural materials or plants around the school. The methods used are lectures, demonstrations, practice, and evaluation. The questionnaires and direct observations on ecoprint products were used as evaluations for this activity. Students have been able to print motifs and colors from leaves and flowers on a cloth to produce ecoprint products according to their respective creativity.
Many low-cost feedstock i.e. used-cooking oil (UCO) for the production of biodiesel fuel (BDF) has contained a large amount of water and high proportion of free fatty acids (FFAs). Therefore, a ...pre-treatment process to reduce the water content (<0.1 wt.%) and FFAs (<2.0 wt.%) were necessary in order to avoid an undesirable side reactions, such as saponification, which could lead to serious problem of product separation and low fatty acid methyl ester (FAME) yield. . In this study, a pre-treatment process of used cooking oil as a feedstock for the production of BDF by using various adsorbents such as Activated Carbon (AC) and various clay minerals, for example Smectite (S), Bentonite (B), Kaolinite (K), and Powdered Earthenware (PE) were evaluated. The oil obtained from pre-treatment was compared with oil without pre-treatment process. In this study, we reported a basic difference in material ability to the oil, depending on the adsorption condition with respect to the physico-chemical parameters, e.g. refractive index (R), density (ρ), FFAs, and water content (W). The results showed that the water content and FFAs in the oil has decreased when using AC as an adsorbent compared with clay minerals. However, the refractive index of oil has similar with the oil without pre-treatment process as well; meanwhile, the density of oil has increased after the pre-treatment process by using clay minerals.
Cervical cancer is the most common cancer in women, and ranks seventh of all cancers worldwide, with 529000 cases in 2008 and more than 85% cases occur in developing countries. One way to treat this ...cancer is through the inhibition of HDAC enzymes which play a strategic role in the regulation of gene expression. Suberoyl Anilide Hydroxamic Acid (SAHA) or Vorinostat is a drug which commercially available to treat the cancer, but still has some side effects. This research present in silico SAHA modification in Zinc Binding Group (ZBG) by organoselenium compound to get ligands which less side effect. From molecular docking simulation, and interaction analysis, there are five best ligands, namely CC27, HA27, HB28, IB25, and KA7. These five ligands have better binding affinity than the standards, and also have interaction with Zn2+ cofactor of inhibited HDAC enzymes. This research is expected to produce more potent HDAC inhibitor as novel drug for cervical cancer treatment.
Hydroxyapatite (HA) is an alloplastic material that is commonly used as a substitute for bone grafts or bone grafts because it has bioactive properties, namely osteoconduction. This study aims to ...improve or develop the function of hydroxyapatite to become a strong and resilient biological device that can withstand loads for appropriate functions such as bone implants. Therefore, it is necessary to modify the structure, among others, by the reinforcement process (composite formation) with other materials.The doping of hydroxyapatite/Al2O3 in this study was carried out using the hydrothermal method. The hydrothermal method is one of the hydroxyapatite synthesis methods carried out at high pressure and temperature to achieve equilibrium. The material used in this study was papai shrimp as a source of calcium. The temperature has an effect in this study where the higher the doping temperature used, the higher the degree of crystallinity, particle size homogeneity, and porosity value. From the doping results, it is known that a temperature of 300°C produces a degree of crystallinity of 54.32% and a crystal size of 3.75 nm with a porosity value of 99.38%. This result is much better than the undoped hydroxyapatite in the previous study.
Cervical cancer is the most common cancer in women, and ranks seventh of all cancers worldwide, with 529000 cases in 2008 and more than 85% cases occur in developing countries. One way to treat this ...cancer is through the inhibition of HDAC enzymes which play a strategic role in the regulation of gene expression. Suberoyl Anilide Hydroxamic Acid (SAHA) or Vorinostat is a drug which commercially available to treat the cancer, but still has some side effects. This research present in silico SAHA modification in Zinc Binding Group (ZBG) by organoselenium compound to get ligands which less side effect. From molecular docking simulation, and interaction analysis, there are five best ligands, namely CC27, HA27, HB28, IB25, and KA7. These five ligands have better binding affinity than the standards, and also have interaction with Zn super(2+) cofactor of inhibited HDAC enzymes. This research is expected to produce more potent HDAC inhibitor as novel drug for cervical cancer treatment.
The Use Of PjBL Integrated STEAM and Students Life Skills in Inorganic ChemistryLearning ABSTRAK Tujuan penelitian ini untuk menerapkan model pembelajaran PjBL (Project Based Learning) yang ...terintegrasi STEAM (Science, Technology, Engineering, Art, Mathematics) dan hubungannya dengan life skill Mahasiswa dalam pembelajaran Kimia Anorganik. Metode pengumpulan data dilakukan menggunakan pre-test dan post-test, project assessment pembuatan Batik serta presentasi Kelompok dari tugas Kelompok dalam LKM (Lembar Kerja Mahasiswa) pada Mata Kuliah Kimia Anorganik III. Tugas Kelompok yang berkaitan dengan Senyawa Koordinasi dan Isomer Senyawa Koordinasi yang dilustrasikan ke dalam Motif Batik Jambi. Art atau seni batik motif “Angso Duo†sebagai ilustrasi isomer levo dan dextro etilendiammintetraasetatokobaltat(III) dimana gugus etilen sebagai ilustrasi pada bagian ekor binatang Angsa. Engineering atau rekayasa dikembangkan melalui bahan pewarna Batik menggunakan bahan alami. Hasil Uji korelasi diperoleh 0,57 nilai signifikasi diperoleh F hitung sebesar 0,006 yang berarti lebih kecil dari 0,05 sebagai F teori. Uji determinasi diperoleh R2 sebesar 0,374 atau l=0,37 % yang menunjukkan bahwa kesesuaian penggunaan model pembelajaran PjBL terintegrasi STEAM dengan life skill mahasiswa pada praktikum pembuatan Batik dengan menggunakan Teori Kimia Anorganik III tergolong kuat (37.4%) dan sisanya dipengaruhi oleh variabel luar (62,6 %). Berdasarkan dari hasil penelitian bahwa diperoleh hasil yang baik, jika pembelajaran PjBL diintegrasikan dengan model STEAM dan dapat diketahui hubungannya dengan life skill yang dikembangkan mahasiswa. Batik dibuat dalam rangka Merdeka Belajar-Kampus Merdeka (MB-KM) untuk bahan baju dengan ukuran 90 x 200 cm sebagai produk karya mahasiswa. Kata Kunci: kimia anorganik, life skill, motif batik jambi, PjBL, STEAM, terintegrasi.
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