ALICE was the first experimental collaboration observing a moderate nuclear suppression down to low Bjorken- x in lead nuclei using coherent J/ ψ photoproduction. In this contribution, we present new ...results extending the studies of the photonuclear cross section by covering the Bjorken- x interval of 1.1 · 10 −5 < x < 3.3 · 10 −2 , corresponding to the photon-nuclear energies 17 < W γPb,n < 920 GeV. This is achieved by using multiple methods to extract the energy dependence, including new results on the forward neutron emission accompanying the coherent photoproduction process. These new results, combined with ALICE measurements of J/ ψ off a proton target, probe the gluonic structure of the lead nuclei at the lowest Bjorken- x possible with any current experiment, challenging both gluon saturation and shadowing models to describe the data.
Residual loads can affect the load transfer and the settlement-induced in-service loadings, although they do not alter the bearing capacity. When residual loads are present and not measured or ...evaluated, the settlement estimate is greater than predicted if these loads are known. Residual loads can be measured when the pile instrumentation is nullified before pile installation, in the case of displacement piles, or before the first loading in non-displacement piles, such as bored cast-in-place piles, continuous flight auger piles, and micro-piles. In the case of underpinning foundation and piled raft, when the loading transfer is shared by the original and new foundation, or by the piles and the raft, it is essential to know the stiffness of each foundation element to estimate the load partition. If residual loads are present, pile stiffness is greater than when not considered in the design. The paper revisits this theme of practical relevance. A historical review of the most relevant research involving pile residual load measurements, pile loading tests including the interpretation of residual loads locked at a pile toe, and a new procedure for residual loads prediction are provided. A comparison is made of the experimental residual loads observed in some of the instrumented cases and the values estimated with the suggested procedure. The development of residual loads at the pile toe as a function of the toe resistance to total capacity ratio is very similar to the variation of the soil density as a function of soil moisture content in soil compaction.
Abstract
Background
Children with cerebral palsy (CP) often have communication impairments, including speech altered intelligibility. Multiple levels of disrupted speech have been reported in CP, ...which negatively impact on participation and quality of life, with increase of care needs. Augmentative Alternative Communication (AAC) is an option, with debated benefits and limitations, in particular for its functional use. This is supported by a substantial lack of defined evidences in favor of direct speech articulation intervention in CP. Motor learning-based interventions are effective in CP and are the basis of speech motor interventions such as PROMPT (Prompts for Restructuring Oral Muscular Phonetic Targets). The PROMPT speech motor treatment provides tactile-kinesthetic inputs to facilitate articulatory movements by dynamic modelling, resulting in more efficient motor patterns that can be integrated into speech and communication. In CP, exploratory evidences support the feasibility and preliminarily advantages on intelligibility of motor speech treatments, such as PROMPT, with increased speech motor control, also documented by kinematic analyses.
Methods
A randomized waitlist-control trial will be conducted in children aged between 3- and 10-years having CP and dysarthria (estimated sample size = 60 children). Children will be allocated in the immediate intervention or in the waitlist control group. The intervention consists of an intensive 3 weeks period of twice-a-day administration of PROMPT. Standard care will be administered in the control (waitlist) group. After repeated baseline assessments (T0), the PROMPT treated group will undergo the experimental 3-week intervention period, with T1 assessment at the end. A further T2 assessment will be provided at medium term (3 months after the end of the intervention) for evaluating the stability of intervention. Primary and secondary speech clinical and kinematics outcome measures will be collected at T0, T1 and T2.
Discussion
This paper describes the study protocol consisting of a RCT with two main objectives: (1) to evaluate the or short-term benefits of an intensive speech motor intervention on speech and intelligibility in children with CP and the stability of the intervention at medium term; (2) to describe the kinematic correlates of speech motor control modifications.
Trial registration
Trial registration date 06/12/2019;
ClinicalTrials.gov
Identifier:
NCT04189159
.
Resumo: Diante do atual contexto em que o mundo se encontra, de caos, de isolamento social e de relações pessoais modificadas abruptamente, a educação foi alterada praticamente de um dia para o ...outro. O objetivo deste trabalho é refletir sobre as possibilidades que as tecnologias digitais móveis trazem para a educação em tempos de pandemia e isolamento. Assim, as tecnologias podem influenciar diretamente no cenário educacional, minimizando efeitos da pandemia para que a educação não pare completamente, para que alunos não fiquem um ano sem escolarização e para que não haja atrasos em calendários. Novos desafios são postos: professores precisam informar-se e formar-se nas tecnologias digitais móveis, alunos precisam se adaptar aos novos estilos de aprendizagem, assim como pais e responsáveis agora possuem mais encargos na educação dos filhos. Todas as esferas da sociedade foram afetadas, no entanto é preciso que tiremos algo disso tudo: novas possibilidades de interação, ensino e aprendizagem.Palavras-chave: Ensino Remoto; Tecnologias; Pandemia; Educação. Reflections and percpetions on mobility and ubiquity of digital technologies in chaotic contextAbstract: Given the current context in which the world finds itself, in a chaos, social isolation and personal relationships abruptly modified in an education was practically changed overnight. The objective of this work is to reflect on the possibilities that digital mobile technologies bring to education in times of pandemic and isolation. Thus, as technologies can directly influence the educational scenario, minimizing pandemic effects so that education does not stop completely, so that students do not go a year without schooling and so that there are no delays in calendars. New challenges are posed: teachers need to be informed and educated about mobile digital technologies, students need to adapt to new learning styles, parents and guardians now have more responsibilities in raising their children. All spheres of society were affected, but we need to get something out of it all: new possibilities for interaction, teaching and learning.Keywords: Remote Teaching; Technologies; Pandemic; Education.
The mineral structure of soft clays is extremely fragile. Sampling operations and laboratory handling cause unavoidable disturbance. Undisturbed sampling is a theoretical concept because the stress ...release imposes disturbance. Consolidation tests on disturbed samples provide one-dimensional (1D)-compression curves very different from field response, which leads to inaccurate settlement estimates. Among the approaches for curve reconstruction, Schmertmann’s method is probably the most commonly adopted in engineering practice. However, it presents difficulties in determining preconsolidation stress. The paper primarily addresses Schmertmann’s and Nagaraj et al.’s propositions and discusses their advantages and shortcomings. A new approach for reconstructing the 1D-compression curve is proposed with the main objective being its independence of the interpretation of the experimental results. The validity was examined by comparing the reconstructed curves with those obtained by other methods. Experimental results on high- and low-quality specimens have been analyzed as well. The results revealed that the reconstructed curves for the cases analyzed are almost unique and independent of specimen quality. The proposed method allows both graphical and analytical implementation and the reconstructed curves are unaffected by experimental curve interpretation.
The ALICE Collaboration has studied coherent J/ψ photoproduction in Pb-Pb ultraperipheral collisions (UPC) since Run 1. The data sample collected during the LHC Run 2 at forward rapidity, i.e. -4 < y ...< -2.5, has opened new possibilities. New differential measurements are feasible, and it is then possible to study the properties of coherent J/ψ . A symmetric collision system such as Pb-Pb has an inherent ambiguity on the sign of the rapidity of the J/ψ with respect to the ion which is emitting the photon. The analysis of coherent J/ψ photoproduction in conjuction with neutron emission provides a viable new route to solve this ambiguity, and to probe for nuclear shadowing effects down to a Bjorken-x of about 10⁻⁵. The two solutions with the forward rapidity acceptance of the ALICE detector are then sensitive to nuclear shadowing at Bjorken-x ≃ 10⁻² and 10⁻⁵. In addition, the dataset also allows for the study of the angular distributions of the decay muons of the J/ψ , thus providing a tool to assess the polarisation of coherently photopro- duced J/ψ. It is found that coherent J/ψ polarisation is measured to be consistent with transverse polarisation.
Infraorbitary artery epistaxis Ruggeri, Carlos Santiago; Zamar, Claudia Esper; Ragoni, Ana
Journal of Otolaryngology-ENT Research,
5/2022, Letnik:
14, Številka:
1
Journal Article
Odprti dostop
Epistaxis is a common complication of endoscopic sinus surgery. Bleeding occurs more frequently due to injury of the sphenopalatine artery branches. Pathologies of the maxillary sinus that produce ...bone resorption and descent from the orbital floor into the sinus, expose the orbital fat and the infraorbital artery (IOA) to an injury that can cause severe epistaxis which is difficult to treat. Two cases of epistaxis due to an injury of the infraorbital artery in the maxillary sinus are described in our study.
Background: Pharyngocutaneous fistula is the most common complication after total laryngectomy. The factors associated with its development have been studied by several authors without conclusive ...results. Objective: To evaluate the causes for the development of PCF and to describe the risk factors associated with PCF in the population studied. Material and methods: We conducted a retrospective and observational study with statistical analysis of the variables. A total of 55 patients undergoing initial or salvage total laryngectomy from January 2000 to December 2019 were included. Male-to-female ratio was 48/7. Mean age was 61.3 years. The pathological diagnosis was epidermoid carcinoma in 96.36% of the cases. Statistical analysis: (chi square test and Mann-Whitney test) of the variables related with the development of pharyngocutaneous fistula. Results: The incidence of fistula in patients with laryngectomy was 20%. Spontaneous closure occurred in 72.73% and 3 patients (27.27%) required the use of flaps. In patients with fistula, 63.64% had previous radiotherapy. In these patients, the use of nasogastric tube feeding lasted > 15 days. Mean length of hospital stay in patients with fistula with 23 days. Conclusion: In our environment, previous radiotherapy was the most significant factor associated with the development of fistula. In these patients, fistula took longer to close and required more complex reconstructions in some cases.
Ultra-peripheral collisions (UPC) are events characterised by large impact
parameters between the two projectiles, larger than the sum of their radii. In
UPCs, the protons and ions accelerated by the ...LHC do not interact via the
strong interaction and can be regarded as sources of quasireal photons.
Photoproduction of vector mesons (e.g. J/$\psi$ and $\psi$') in UPC is quite
interesting since it is sensitive to the low-$x$ gluon density. Owing to the
statistics available from Run 2 data, the ALICE Collaboration has been able to
carry out differential measurements, such as the measurement of the
rapidity-differential cross section of coherent J/$\psi$ production in Pb--Pb
UPCs and the $t$-dependence of coherent and incoherent J/$\psi$, which are
sensitive to the average of the spatial distribution of the gluons and its
variance, respectively. In addition, the ALICE Collaboration has measured the
energy dependence of the photonuclear cross section with a few different
strategies, such as by measuring the rapidity-differential cross section of
coherent J/$\psi$ production in different impact parameter ranges i.e. in
ultra-peripheral and peripheral collisions, and in neutron emission classes.
The latter two provide promising tools for the resolution of the ambiguity in
Bjorken-$x$ which arises in symmetric A--A UPCs.
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