We report results from the second and third seasons of observation with the QUaD experiment. Angular power spectra of the Cosmic Microwave Background are derived for both temperature and polarization ...at both 100 GHz and 150 GHz, and as cross frequency spectra. All spectra are subjected to an extensive set of jackknife tests to probe for possible systematic contamination. For the implemented data cuts and processing technique such contamination is undetectable. We analyze the difference map formed between the 100 and 150 GHz bands and find no evidence of foreground contamination in polarization. The spectra are then combined to form a single set of results which are shown to be consistent with the prevailing LCDM model. The sensitivity of the polarization results is considerably better than that of any previous experiment -- for the first time multiple acoustic peaks are detected in the E-mode power spectrum at high significance.
In this paper we present a parameter estimation analysis of the polarization and temperature power spectra from the second and third season of observations with the QUaD experiment. QUaD has for the ...first time detected multiple acoustic peaks in the E-mode polarization spectrum with high significance. Although QUaD-only parameter constraints are not competitive with previous results for the standard 6-parameter LCDM cosmology, they do allow meaningful polarization-only parameter analyses for the first time. In a standard 6-parameter LCDM analysis we find the QUaD TT power spectrum to be in good agreement with previous results. However, the QUaD polarization data shows some tension with LCDM. The origin of this 1 to 2 sigma tension remains unclear, and may point to new physics, residual systematics or simple random chance. We also combine QUaD with the five-year WMAP data set and the SDSS Luminous Red Galaxies 4th data release power spectrum, and extend our analysis to constrain individual isocurvature mode fractions, constraining cold dark matter density, alpha(cdmi)<0.11 (95 % CL), neutrino density, alpha(ndi)<0.26 (95 % CL), and neutrino velocity, alpha(nvi)<0.23 (95 % CL), modes. Our analysis sets a benchmark for future polarization experiments.
We describe the QUaD experiment, a millimeter-wavelength polarimeter designed to observe the Cosmic Microwave Background (CMB) from a site at the South Pole. The experiment comprises a 2.64 m ...Cassegrain telescope equipped with a cryogenically cooled receiver containing an array of 62 polarization-sensitive bolometers. The focal plane contains pixels at two different frequency bands, 100 GHz and 150 GHz, with angular resolutions of 5 arcmin and 3.5 arcmin, respectively. The high angular resolution allows observation of CMB temperature and polarization anisotropies over a wide range of scales. The instrument commenced operation in early 2005 and collected science data during three successive Austral winter seasons of observation.
QUaD is a bolometric CMB polarimeter sited at the South Pole, operating at frequencies of 100 and 150 GHz. In this paper we report preliminary results from the first season of operation (austral ...winter 2005). All six CMB power spectra are presented derived as cross spectra between the 100 and 150 GHz maps using 67 days of observation in a low foreground region of approximately 60 square degrees. This data is a small fraction of the data acquired to date. The measured spectra are consistent with the LCDM cosmological model. We perform jackknife tests which indicate that the observed signal has negligible contamination from instrumental systematics. In addition by using a frequency jackknife we find no evidence for foreground contamination.
Many studies of Ca
effects on mitochondrial respiration in intact cells have used electrical and/or chemical stimulation to elevate intracellular Ca
, and have reported increases in NADH and ...increased ADP/ATP ratios as dominant controllers of respiration. This study tested a different form of stimulation: brief temperature increases produced by pulses of infrared light (IR, 1,863 nm, 8-10°C for ∼5 s). Fluorescence imaging techniques applied to single PC-12 cells in low µM extracellular Ca
revealed IR stimulation-induced increases in both cytosolic (fluo5F) and mitochondrial (rhod2) Ca
. IR stimulation increased O
consumption (porphyrin fluorescence), and produced an alkaline shift in mitochondrial matrix pH (Snarf1), indicating activation of the electron transport chain (ETC). The increase in O
consumption persisted in oligomycin, and began during a decrease in NADH, suggesting that the initial increase in ETC activity was not driven by increased ATP synthase activity or an increased fuel supply to ETC complex I. Imaging with two potentiometric dyes tetramethyl rhodamine methyl ester (TMRM) and R123 indicated a depolarizing shift in ΔΨ
that persisted in high K
medium. High-resolution fluorescence imaging disclosed large, reversible mitochondrial depolarizations that were inhibited by cyclosporin A (CSA), consistent with the opening of transient mitochondrial permeability transition pores. IR stimulation also produced a Ca
-dependent increase in superoxide production (MitoSox) that was not inhibited by CSA, indicating that the increase in superoxide did not require transition pore opening. Thus, the intracellular Ca
release that follows pulses of infrared light offers new insights into Ca
-dependent processes controlling respiration and reactive oxygen species in intact cells.
Pulses of infrared light (IR) provide a novel method for rapidly transferring Ca
from the endoplasmic reticulum to mitochondria in intact cells. In PC12 cells the resulting ETC activation was not driven by increased ATP synthase activity or NADH. IR stimulation produced a Ca
-dependent, reversible depolarization of ΔΨ
that was partially blocked by cyclosporin A, and a Ca
-dependent increase in superoxide that did not require transition pore opening.
Mon.Not.Roy.Astron.Soc. 363 (2005) 1125-1135 We present coincident observations of the Cosmic Microwave Background (CMB)
from the Very Small Array (VSA) and Cosmic Background Imager (CBI) telescopes.
...The consistency of the full datasets is tested in the map plane and the Fourier
plane, prior to the usual compression of CMB data into flat bandpowers. Of the
three mosaics observed by each group, two are found to be in excellent
agreement. In the third mosaic, there is a 2 sigma discrepancy between the
correlation of the data and the level expected from Monte Carlo simulations.
This is shown to be consistent with increased phase calibration errors on VSA
data during summer observations. We also consider the parameter estimation
method of each group. The key difference is the use of the variance window
function in place of the bandpower window function, an approximation used by
the VSA group. A re-evaluation of the VSA parameter estimates, using bandpower
windows, shows that the two methods yield consistent results.
We present coincident observations of the Cosmic Microwave Background (CMB) from the Very Small Array (VSA) and Cosmic Background Imager (CBI) telescopes. The consistency of the full datasets is ...tested in the map plane and the Fourier plane, prior to the usual compression of CMB data into flat bandpowers. Of the three mosaics observed by each group, two are found to be in excellent agreement. In the third mosaic, there is a 2 sigma discrepancy between the correlation of the data and the level expected from Monte Carlo simulations. This is shown to be consistent with increased phase calibration errors on VSA data during summer observations. We also consider the parameter estimation method of each group. The key difference is the use of the variance window function in place of the bandpower window function, an approximation used by the VSA group. A re-evaluation of the VSA parameter estimates, using bandpower windows, shows that the two methods yield consistent results.
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